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TABLE 1 2011 PHARMACEUTICAL MARKET PERFORMANCE BY SEGMENT Market Segment % Growth 2011 over 2010 Total Market -1.0 Brand Market* 0.5 Biotechnology** 12.5 Oncology 2.4 Generics Market -5.3 Source: IMS Brogan, Canadian Drug Store and Hospital Purchases, MAT December 2011. Estimated value of ethical products purchased by retail pharmacies and hospitals at invoice price. * The Brand Market segment definition includes the Biotech and Oncology segments. Numbers are NOT mutually exclusive and will not add to 100%. **Biotechnology market segment includes certain Oncology products. 1 TABLE 2 BRAND vs. GENERIC PRESCRIPTIONS DISPENSED, 2011† Canada and by province Brand (%) Generic (%) 39.7 60.3 QUEBEC 41.6 58.4 ONTARIO 39.1 60.9 ALBERTA 37.9 62.1 SASKATCHEWAN 38.2 61.8 NOVA SCOTIA 39.7 60.3 NEW BRUNSWICK 37.0 63.0 MANITOBA 35.5 64.5 BRITISH COLUMBIA 37.2 62.8 PEI 40.1 59.9 NFLD/LABRADOR 38.2 61.8 CANADA Source: IMS Brogan, Canadian CompuScript † Percentage of prescriptions dispensed through retail pharmacies. Includes new and refills. 2 TABLE 3 PRESCRIPTIONS DISPENSED IN RETAIL PHARMACIES PER CAPITA, BY PROVINCE†‡, 2011 2011 Retail spending per capita* ($) CANADA QUEBEC‡ NEW BRUNSWICK NFLD/LABRADOR NOVA SCOTIA 2011 Prescriptions per capita 690 16 850 27 855 14 835 15 816 13 PEI ONTARIO 702 12 665 13 SASKATCHEWAN 621 13 MANITOBA 604 12 ALBERTA 610 10 BRITISH COLUMBIA 533 10 Source: IMS Brogan, Canadian CompuScript Audit, and Statistics Canada † Population numbers based on Statistics Canada population estimates dated September 29, 2010. Prescriptions in Quebec are normally of a shorter duration than all other provinces; therefore, the number of retail prescriptions dispensed is higher. * Includes cost of drugs plus any mark-ups and pharmacists’ professional fees. Excludes hospitals. ‡ 3 TABLE 4 TOP 10 PHARMACEUTICAL CORPORATIONS IN CANADA, 2011 Purchases by pharmacies and hospitals† Rank 2011 Corporation1 ($ billion) % Change over 2010 1 Johnson & Johnson 1.75 6.6 2 AstraZeneca 1.68 3.0 3 Pfizer 1.57 -25.5 4 Teva Canada 1.21 -24.1 5 Apotex 1.21 -10.7 6 Merck Canada Inc 1.11 6.2 7 Novartis 0.98 1.9 8 GlaxoSmithKline 0.93 -4.2 9 Abbott 0.88 4.7 10 Roche 0.73 5.0 Source: IMS Brogan, Canadian Drugstore & Hospital Purchases Audit 1 Corporations include all divisions or subsidiaries that manufacture pharmaceutical products. Invoice price. All dollar figures in Canadian funds. Does not include purchases made by Canadian internet pharmacies for sale to U.S. customers. † 4