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Edible Cell Mitosis Materials: 3 colours string licorice (2 strings of each) 2 Hershey’s kisses 4 Nibs 2 pairs of gummy worms Directions: 1. Place a few pieces of paper on your desk so that the candy does not come in contact with your desk. 2. IMPORTANT: At each stage take a picture the next one. before you move on to 3. Interphase: Create a cell that is in interphase. a. Use one colour of string licorice to make the cell membrane. Wrap the entire string around to make the circle. b. Use half of the other colour string licorice to make the nuclear membrane in the centre of the cell. c. Place two gummy worms inside the nucleus. These are the chromosomes. d. Add a Hersey’s kiss to the nucleus. This is your nucleolus. e. Place two nibs next to each other in the cell. This is your pair of centrioles within the centrosome. 4. In Interphase the cell grows and replicates its DNA. a. Add another piece of licorice to the cell membrane and the other half of the nuclear membrane licorice to the nuclear membrane to make each circle larger. b. Add two more gummy worms into the nucleus. Make sure that identical gummy worms are placed beside each other. Each gummy worm now represents a sister chromatid and a pair of gummy worms represents a chromosome. c. At this point the centrosome also replicates. Place another two nibs besides the first two. 5. Your cell is now going to go through Mitosis a. Prophase i. Move the centrosomes with the centriole pairs to opposite side of the cell. ii. Rip off four pieces of string licorice that are long enough to reach from the centrosomes to the middle of the cell. Place two strings beside each centrosome. These strings are now your spindle fibers. iii. Remove your nuclear membrane. iv. Separate your chromosomes into pairs of touching sister chromatids. v. Remove the nucleolus. b. Metaphase i. Tie each spindle fiber to one of the chromosomes. Two spindle fibers from the opposite centrosomes should be attached to one chromosome. The point of attachments is called the centromere. ii. Pull the chromosomes until they line up in the centre of the cell. c. Anaphase i. Separate the sister chromatids from each other. ii. Using the spindle fibers, have one person pull two of the newly formed chromosomes to one side of the cell while the other person pulls the other two chromosomes to the other side of the cell. iii. Each side of the cell should now have chromosomes that have the same appearance. d. Telophase i. Pinch the cell membrane together in the centre of the cell to make two circles. Separate the circles from each other. This is called Cytokinesis. You now have two daughter cells. ii. Reform the nuclear membrane in each daughter cell. iii. Put the chromosomes in random order inside the nucleus. iv. Place a nucleolus inside each nucleus. v. Place the centrosome with the pair of centrioles near the nucleus. vi. Remove the spindle fibers. (You may now eat them) Your cell is now finished Mitosis and each daughter cell can grow and begin the process again. You may eat the rest of the candy!!! 6. You should have collected six pictures throughout this process. Please copy these onto a computer and place them on a word document in the correct order that they occur. Label each phase and print. Remember to include the group members’ names. Hand in to Mrs. Graham.