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THERAPEUTIC DRUG MONITORING SERVICE RADBOUD UNIVERSITY NIJMEGEN MEDICAL CENTRE – CLINICAL PHARMACEUTICAL LABORATORY Geert Grooteplein 10, 6525 GA Nijmegen. T: +31243614163; Attn: Dr. Roger JM Brüggemann CONTACT DETAILS (for correspondence of results) Dr: Hospital Tel. nr :………………………………………………………………… :………………………………………………………………… :………………………………………………………………… PATIENT IDENTIFICATION (add label or fill in data) Name Gender Date of Birth Weight Length :………………………………………………………………… :………………………………………………………………… :………………………………………………………………… :………………………………………………………………… :………………………………………………………………… Female O Male O dd/mm/yy kg cm ANTIFUNGAL DRUG TO BE DETERMINED O fluconazole O itraconazole O voriconazole O posaconazole O isavuconazole O liposomal amphotericin B O anidulafungin O caspofungin O micafungin DRUG DATA ON USE (must be fully completed) Start of therapy Time of last intake Time of sample O taken during meal :………………………………………………………… dd/mm/yy :………………………………………………………… dd/mm/yy ; hh:mm :………………………………………………………… dd/mm/yy ; hh:mm O taken after meal O nutritional supplement O no meal given REASON FOR TDM (must be fully completed) O sub-efficacy O toxicity O compliance DOSE OF ANTIFUNGAL DRUG O other (specify) (must be fully completed) O ……. mg ……….. times daily O other: O intravenous administration O oral administration INDICATION OF ANTIFUNGAL THERAPY O primary prophylaxis O secondary prophylaxis O primary therapy O secondary therapy FOCUS OF INFECTION O pulmonary O hepatic (multiple answers possible) O cerebral O other:………………………….……………………(please specify) CAUSATIVE MICRO-ORGANISM O Aspergillus O Mucorales O Candida O other:………………………….…………………..……… (specify) PREVIOUS ANTIFUNGAL TREATMENTS (last 30 days) O fluconazole O itraconazole O voriconazole O posaconazole O isavuconazole O liposomal amphotericin B OTHER DRUG GIVEN CONCOMITTANTLY O dexamethasone O ranitidine O anidulafungin O caspofungin O micafungin (please specify) O (es)omeprazole O rifampin O metoclopramide O PATIENT CHARACTERISTICS O pantoprazole O (multiple answers possible) O hematological malignancy: ……………………….…………………………………(please specify) O neutropenia O GvHD O HSCT O corticosteroid use O other:………………………….…………………....(please specify) Antifungal drug samples are preferably drawn in a Lithium Heparine tube without gel (dark green cap). Please sent sample together with the completed sheet to the address mentioned in the header. VERSION NUMBER 1.0