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ANDREA SWEI San Francisco State University 722 Hensill Hall San Francisco, CA 94132 Department of Biology Phone: (415) 338-1753 e-mail: [email protected] CURRENT ACADEMIC APPOINTMENTS 2013-present Assistant Professor of Biology-San Francisco State University 2011-present Research Associate-Viral Diagnostics and Discovery Center, UC San Francisco EDUCATION 2009 2000 University of California, Berkeley, PhD Department of Integrative Biology University of California, Berkeley, B.A. Department of Integrative Biology with Honors, May 2000 PROFESSIONAL EXPERIENCE 2011-2012 Ruth L. Kirschstein Postdoctoral Fellow: UC San Francisco, Department of Laboratory Medicine, San Francisco, CA. Investigating the pathogenicity of tickborne pathogens and developing diagnostic techniques for emerging diseases. • Development of the first high-density pan-tick pathogen microarray • Development of metagenomic analyses to identify pathogens and host biomarkers in the largest longitudinal dataset of acute Lyme disease patients • Identifying the etiological agent of the newly emerging tick-borne disease, Southern Tick-Associated Rash illness (STARi) using microarray and deep sequencing analyses 2009-2011 Postdoctoral Associate on NSF funded grant: UC Berkeley and Cary Institute of Ecosystem Studies, Millbrook, NY. Investigated the dynamics of Lyme disease through mathematical models and genetic diagnostic analyses. Development of deterministic models of Lyme disease risk as measured by the density of infected ticks Phylogenetic and population genetic analyses of the Lyme disease bacterium 2008-2009 Graduate Student Researcher on NSF Ecology of Infectious Disease (EID) grant: UC Berkeley, Department of Integrative Biology. Developed a 5-year NSF EID grant and led the project in the field and lab. Designed protocols and experiments for field and lab experiments to study the ecology of Lyme disease Oversaw all field and lab data collection and processing Andrea Swei 2 Managed all personnel including lab assistants, undergraduates, and volunteers Responsible for data collection, molecular analysis, data analysis, and interpretation and presentation of results 2005-2008 NSF Predoctoral Research Fellow: UC Berkeley, Department of Integrative Biology. Developed a research project examining the impact of habitat fragmentation from an invasive plant species on the dynamics of Lyme disease ecology. Developed protocols for field and lab experiments to study the interaction of a plant pathogen and a vector-borne zoonotic disease Designed a quantitative real-time PCR assay for the Lyme disease bacterium PUBLICATIONS Swei, A., R.S. Lane, V.L. Bowie, R.C.K. Bowie. In review. Comparative genetic diversity of Lyme disease bacteria in ticks and their vertebrate hosts. Ticks and Tick-borne diseases. Swei, A., Russell, B.J., Naccache, S., Kabre, B., Veeraraghaan, N., Pilgard, M., Johnson, B.J.B., Chiu, C.Y. 2013. The genome sequence of Lone Star virus, a highly divergent bunyavirus found in the Amblyomma americanum tick. PlosOne 8(4): e62083. doi:10.1371/journal.pone.0062083 Swei, A., R.S. Ostfeld, R.S. Lane, C.J. Briggs. 2012. Impacts of an introduced forest pathogen on risk of Lyme disease in California. Vector Borne Zoonotic Diseases 12(8): 623-632. Swei, A., J.J.L. Rowley, D. Rödder, M.L.L. Diesmos, A.C. Diesmos, C.J. Briggs, R. Brown, T.T. Cao, T.L. Cheng, R.A. Chong, B. Han, J.-M. Hero, H.D. Hoang, M.D. Kusrini, D.T.T. Le, J.A. McGuire, M. Meegaskumbura, M.S. Min, D.G. Mulcahy, T. Neang, S. Phimmachak, D.Q. Rao, N.M. Reeder, S.D. Schoville, N. Sivongxay, N. Srei, M. Stöck, B.L. Stuart, L.S. Torres, D.T.A. Tran, , T.S. Tunstall, D. Vieites, V.T. Vredenburg. 2011. Is chytridiomycosis an emerging infectious disease in Asia? PLoS ONE 6(8): e23179. doi:10.1371/journal.pone.0023179 Swei, A., C.J. Briggs, R.S. Lane, R.S. Ostfeld. 2011a. Impact of lizard removal on the abundance and infection prevalence of a Lyme disease vector. Proceedings of the Royal Society B, 278 (1720): 2970-2978 *Faculty of 1000 recommended article Swei, A., R. Meentemeyer, C.J. Briggs. 2011b. Influence of abiotic and environmental factors on the density and infection prevalence of Ixodes pacificus (Acari:Ixodidae) with Borrelia burgdorferi. Journal of Medical Entomology, 48 (1): 20-28. Swei, A., Ostfeld, R.S., Lane, R.S., Briggs, C.J. 2011c. Effects of an invasive forest pathogen on abundance of vertebrate hosts in a California Lyme disease focus. Oecologia, 166 (1): 91100. Killilea, M. E., Swei, A., Lane, R.S., Briggs, C.J., and Ostfeld, R.S. 2008. Spatial dynamics of Lyme disease: A review. EcoHealth, 5(2): 167-195. Andrea Swei 3 Lloyd-Smith, J.O., Cross, P.C., Briggs, C.J., Daugherty, M., Getz, W.M., Latto, J., Sanchez, M.S., Smith, A.B., Swei, A. 2005. Should we expect population thresholds in wildlife disease? Trends in Ecology and Evolution 20 (9); 511-519. Swei, A., Brylski, P.V., Spencer, W.D., Dodd, S.C., Patton, J.L. 2003. Hierarchical genetic structure in fragmented populations of the little pocket mouse (Perognathus longimembris) in Southern California. Conservation Genetics 4; 501-514. GRANTS AND AWARDS 5/2011-current Principal Investigator-QB3 award, Swartz foundation: “Improved Diagnostics for Acute and Chronic Lyme Disease”, $200,000 2/2012-current Principle Investigator-National Research Fund for Tick-borne diseases pilot project grant: “Using Pan-Pathogen Microarrays and Deep Sequencing to Search for the Cause of Southern Tick-Associated Rash Illness (STARI)”, $50,000 10/2011-10/2012 Principle Investigator-Rufford Foundation Grant: “Conservation of montane forest anurans in southeastern Peru”, $10,000 2011 NIH Ruth L. Kirschstein Postdoctoral fellowship, $45,000 2007, 2011 Burroughs Wellcome Travel Scholarship recipient, $2,000 2005 National Science Foundation, Graduate Research Fellowship recipient, $90,000 2005 Graduate Researcher: National Science Foundation Ecology of Infectious Diseases grant, $800,000 2005 American Society of Mammalogists, Grants in Aid of Research recipient, $1,000 2004 Sigma Xi, Grants in Aid of Research recipient, $1,000 2000 Received B.A. with honors from the department of Integrative Biology, UC Berkeley. 2000 Undergraduate research honors thesis: Historic and ongoing population genetics of the pacific pocket mouse (Perognathus longimembris pacificus) TEACHING EXPERIENCE 2013 Disease Ecology – Instructor of record for developing new course of the ecology of infectious diseases 2010-2011 Lecturer for UC Berkeley’s Fall Program for Freshman – The Biosphere (ESPM 2) – Course instructor – Developed course curriculum and lectured a freshman course for two terms 2007 Graduate Student Instructor: Biology and Geomorphology of Tropical Islands (IB158), Moorea French Polynesia research station, UC Berkeley – Key instructor in a full-immersion, study abroad program. 2004-2005 Graduate Student Instructor: Natural History of the Vertebrates (IB104), UCB 2003-2004 Graduate Student Instructor: Biology-Field ecology section (Bio 1B), UCB SCIENTIFIC CONFERENCES 2014 Interscience Conference on Antimicrobial Agents and Chemotherapy, Poster presentation: “Human Transcriptome Profiling for the Diagnosis of Acute Lyme Disease” Washington D.C. Andrea Swei 2013 2011 2011 2011 2011 4 International Conference on Lyme Borreliosis and other Tick-borne Diseases, Boston, MA-Oral presentation:”Development and validation of metagenomicsbased diagnostics for targeting Lyme disease and associated tick-borne diseases” Ecological Society of America, Austin, TX-Oral presentation: “The dual-role of lizards in the ecology of Lyme disease in the far-western United States” Ecology and Evolution of Infectious Diseases, Santa Barbara, CA - Oral presentation: “Community interactions in Lyme disease ecology: forests and hosts as habitat islands” Ecology and Evolution of Infectious Diseases, Principal Investigators meeting, Madison, WI - Oral presentation: “Experimental removal of lizards from a Lyme disease system” Ecology and Evolution of Infectious Diseases, Principal Investigators meeting, Atlantic City, NJ- Oral presentation: “Dual role of lizards in Lyme disease ecology” INVITED RESEARCH SEMINARS 2014 University of California, Santa Barbara Department of Ecology, Evolution, and Marine Biology: “Tick-borne diseases in ecological communities” 2013 Emory University, Department of Population Biology, Ecology, and Evolution: “Scaling from ecological communities to genomes: understanding emerging tickborne pathogens” 2013 California Academy of Sciences Seminar Series “Utilizing metagenomics in the study of emerging tick-borne diseases” 2008 Stanford University, Department of Human Biology 2008 Cary Institute for Ecosystem Studies ACADEMIC SERVICE Reviewer for scientific journals including: American Naturalist, Journal of Theoretical Biology, Herpetological Review, PlosOne, Ecology Letters