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(a) 357 entries 0 50 100 150 200 250 300 350 400 Number of LGTs Amino Acid Metabolism Glycan Metabolism Energy Metabolism Carbohydrate Metabolism Cofactors and Vitamins Other Metabolic Pathways (b) 40% 35% 30% 25% 20% 15% 10% 5% 0% Nucleotide Metabolism Membrane Transport Hypothetical Proteins (c) 35% Mucosal parasites (112) E. histolytica (31) Insect transmitted blood parasites (41) p-value= 0.063 Fraction of LGTs Fraction of LGTs 45% Genetic Information Processing Lipid Metabolism Enzyme Reactions 30% D. discoideum (27) 25% 20% 15% 10% 5% 0% p-value= 0.024