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The Integumentary System Chapter 5 SKIN STRUCTURE SKIN FUNCTIONS Protection Body temperature regulation Cutaneous sensation Metabolic functions Blood reservoir Excretion of wastes EPIDERMIS Cell Types Keratinocytes Melanocytes Langerhans’ cells Merkel cells EPIDERMIS Layers Stratum basale Stratum spinosum Stratum granulosum Stratum lucidum Stratum corneum DERMIS SKIN PIGMENTATION Melanin Carotene Hemoglobin ACCESSORY OGRANS Sweat glands Eccrine Apocrine Ceruminous Mammary Sebaceous glands Holocrine ACCESSORY ORGANS Hair Hair follicle receptor (root hair plexus) Hair papilla Connective tissue root sheath Epithelial root sheath Hair matrix Arrector pili muscle Life cycle Active growth phase—weeks to years Regressive phase Resting phase—1-3 months ACCESSORY ORGANS ACCESSORY ORGANS SKIN DISORDERS Skin cancer UV radiation damages cell DNA Disables tumor suppressor gene Basal Cell Carcinoma Squamous cell carcinoma Least malignant Stratum basale cells invade dermis & hypodermis Keratinocytes of stratum spinosum Melanoma Most dangerous melanin SKIN DISORDERS SKIN DISORDERS Skin cancer Burns Dehydration more danger than infection 1st degree—only epidermis 2nd degree—epidermis & part of dermis 3rd degree—epidermis, dermis, often part of hypodermis SKIN DISORDERS Rule of Nines SKIN DISORDERS Dermatitis Contact dermatitis Acne Alopecia Skin Disorders Rosacea Seborrhea Skin Disorders Hirsutism Impetigo Skin Disorders Psoriasis Albinism