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The Integumentary
System
Chapter 5
SKIN STRUCTURE
SKIN FUNCTIONS
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Protection
Body temperature regulation
Cutaneous sensation
Metabolic functions
Blood reservoir
Excretion of wastes
EPIDERMIS
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Cell Types
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Keratinocytes
Melanocytes
Langerhans’ cells
Merkel cells
EPIDERMIS
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Layers
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Stratum basale
Stratum spinosum
Stratum
granulosum
Stratum lucidum
Stratum corneum
DERMIS
SKIN PIGMENTATION
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Melanin
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Carotene
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Hemoglobin
ACCESSORY OGRANS
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Sweat glands
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Eccrine
Apocrine
Ceruminous
Mammary
Sebaceous glands
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Holocrine
ACCESSORY ORGANS
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Hair
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Hair follicle receptor (root hair plexus)
Hair papilla
Connective tissue root sheath
Epithelial root sheath
Hair matrix
Arrector pili muscle
Life cycle
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Active growth phase—weeks to years
Regressive phase
Resting phase—1-3 months
ACCESSORY ORGANS
ACCESSORY ORGANS
SKIN DISORDERS
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Skin cancer
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UV radiation damages cell DNA
Disables tumor suppressor gene
Basal Cell Carcinoma
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Squamous cell carcinoma
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Least malignant
Stratum basale cells invade dermis & hypodermis
Keratinocytes of stratum spinosum
Melanoma
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Most dangerous
melanin
SKIN DISORDERS
SKIN DISORDERS
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Skin cancer
Burns
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Dehydration more danger than infection
1st degree—only epidermis
2nd degree—epidermis & part of dermis
3rd degree—epidermis, dermis, often part
of hypodermis
SKIN DISORDERS
Rule of Nines
SKIN DISORDERS
Dermatitis
 Contact dermatitis
 Acne
 Alopecia
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Skin Disorders
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Rosacea
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Seborrhea
Skin Disorders
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Hirsutism
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Impetigo
Skin Disorders
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Psoriasis
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Albinism
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