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ASSESS
Patient has ocular hypertension of
>24 mm Hg, and family history of
glaucoma. Patient wants to know if
POAG can be prevented? Question
of Therapy/Prevention
60 year old patient with myopia,
family history of glaucoma, and
cardiovascular disease. Patient
wants to know what tests should be
done?
Question of Diagnosis
ASK (PICO)
P In a patient with ocular hypertension
(IOP)
I would therapy with timolol
C versus no treatment
O decrease the risk of developing
glaucoma?
P In a patient with conditions associated
with increased risk for glaucoma
I would frequency-doubling technology
(FDT) perimetry
C be more effective than Damato
campimetry
O to screen for glaucoma?
P In a patient with wet macular
degeneration
I is Avastin
C as effective as Lucentis
O in improving visual acuity?
ACQUIRE (4 S)
1. Dynamed
2. ACP PIER
3. Cochrane DSR or other
systematic review
4. Ovid MEDLINE
APPRAISE
Randomized Controlled Trial
Filter (Level of Evidence, e.g.,
A-C, 1-3, etc.)
1. Dynamed
2. ACP PIER
3. Cochrane DSR or other
systematic review
4. Ovid MEDLINE
Prospective Cohort Study
Blind comparison to gold
standard
Filter (Level of Evidence, e.g.,
A-C, 1-3, etc.)
Patient is a retired teacher and has
1. Dynamed
Randomized Controlled Trial
wet macular degeneration. He is
2. ACP PIER
Filter (Level of Evidence, e.g.,
concerned about the cost of the
3. Cochrane DSR or other
A-C, 1-3, etc.)
treatment, Lucentis, that you have
systematic review
recommended. Is there a more cost
4. Ovid MEDLINE
effective alternative? Question of
Therapy
Patient is a broadcast news reporter, P In a patient with dry eye syndrome
1. Dynamed
Randomized Controlled Trial
wears contacts, and has dry eye
I are omega-3 or omega-6 fatty acids
2. ACP PIER
Filter (Level of Evidence, e.g.,
syndrome. Eye drops have not
effective
3. Cochrane DSR or other
A-C, 1-3, etc.)
helped and she wants to know if
C versus no treatment
systematic review
omega fatty acid supplements might O in relieving dryness?
4. Ovid MEDLINE
relieve her symptoms. Question of
Therapy
Patient has Fuch’s dystrophy with
P In a patient with early Fuch’s dystrophy
1. Dynamed
Cohort, Case Control, Case
central corneal guttae and no
I at what stage is corneal transplantation
2. ACP PIER
Series
edema. She is 37 years old and
C none
3. Cochrane DSR or other
Filter (Level of Evidence, e.g.,
wants to know how soon she might O indicated for vision loss?
systematic review
A-C, 1-3, etc.)
need surgery. Question of
4. Ovid MEDLINE
Prognosis
Evidence Based Retrieval and Appraisal Worksheet – OPT 6162. Sandra Martin, M.L.I.S., Lecture 11/22/10
APPLY
Can the results
be used in care
of this patient?