Download RONG-SEN, YANG (楊榮森)

RONG-SEN, YANG (楊榮森)
by sharon, 2011-01-26 15:19, 人氣(434)
PROFESSOR
CANCER RESEARCH, OSTEOPOROSIS AND BONE
METABOLISM, BONE INFLAMMATION
Our group focus on the regulatory role of endocrine
factors and inflammatory factors in bone cancer, bone
tissue metabolism and joint inflammation. In cancer
research, we interest in the expression of growth factors
and angiogenic factors in bone tumor and clarifying
the mechanisms of angiogenesis and metastasis in
bone tumor (J Bone J Surg am 2005; Clin Oncol 2005;
Knee 2009). We also indentify the regulatory effects
of growth factors in bone-migrating cancer cell such
as lung cancer (Carcinogenesis 2008) and prostate
cancer (Prostate 2008). In osteoporosis, we find the
risk factors in aged women to measure the score of
osteoporosis and prevent the fracture in spine and hip
(Clin Rehab 2005; Spine 2005; BMC musculoskelet
Disord 2009; Clin Rehab 2009) Furthermore, we try
to figure out the mechanisms how bone-associated
disorder occurs, we are interested in investigating the
mechanisms regarding how endocrine factors regulates
the differentiation and maturation in bone-associated
cells including osteoblasts, osteoclasts, skeletal muscle
and adipocytes (J Biol Chem 2005; J Cell Physiol 2007;
Bone; 2007; Endocrinology 2007; J Cell Physiol 2010).
Otherwise we are interested in the application and
molecular mechanisms of therapeutic ultrasound (Bone
2005; Mol Pharmacol 2006; J Biol Chem 2007; J Cell
Physiol 2008)
The mechanism how HO-1 inhibits the differentiation
of osteoblasts.
• Lin TH, Yang RS, Tang CH, Lin CP, Fu WM, PPARγ inhibits osteogenesis
via the down-regulation of the expression of COX-2 and iNOS in rats.
Bone. 2007;41(4):562-74.
• Lin TH, Tang CH, Hung SY, Liu SH, Lin YM, Fu,WM, Yang RS.
Upregulation of Heme Oxygenase-1 Inhibits the Maturation and
Mineralization of Osteoblasts. J Cell Physiol. 2010;222(3):757-68.