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Curriculum Vitae I. General Biographical Information A. Personal 1. Name: Nadim Nasir, Jr., M.D. 2. Place of Birth: Houston, Texas, Citizenship: United States B. Education: 1. 1977-‐1981: University of Houston, Bachelor of Science, Biology 2. 1982-‐1986: University of Texas Southwestern Medical School, Doctor Of Medicine 3. 1986-‐1989: Parkland Memorial Hospital Dallas V.A. Medical Center, Residency in Internal Medicine 4. 1989-‐1992: Baylor College of Medicine, Fellowship in Cardiovascular Disease and Electrophysiology C. Academic Appointments: 1. Faculty Positions at The Methodist Hospital System, Houston, Texas: a. 2006-‐present: 1. Deputy Chair, Department of Cardiology, The Methodist Hospital, Houston, Texas 2. Clinical Director of Electrophysiology Services, The Methodist Debakey Heart Center, Houston 3. Medical Director of Centralized Telemetry, The Methodist Hospital, Houston, Texas b. 2005-‐present: Medical Director of Electrophysiology Lab, The Methodist Hospital, Houston, Texas c. 2003-‐present: Active Staff, Cardiology and Electrophysiology, Methodist Willowbrook Hospital, Houston, Texas d. 1992-‐present: Active Staff, Cardiology and Electrophysiology, The Methodist Hospital, Houston, Texas 2. Previous Faculty Position at St. Luke’s Episcopal Hospital, Houston, Texas a. 1992-‐11/30/2009 Courtesy Staff, Cardiology and Electrophysiology 3. Faculty Appointments at Other Institutions while at The Methodist Hospital, Houston, Texas: a. 2010-‐present: Clinical Associate Professor of Medicine, Baylor College of Medicine, Houston, Texas b. 2009-‐present: Active Staff, Cardiology and Electrophysiology, MD Anderson Cancer Center, Houston, Texas c. 2006-‐present: Active Staff, Cardiology and Electrophysiology, Tomball Regional Hospital, Tomball, Texas d. 2001-‐present: Clinical Assistant Professor of Medicine, Division of Cardiology, Department of Internal Medicine, Baylor College of Medicine, Houston, Texas e. 1999-‐present: Clinical Assistant Professor of Medicine, Baylor College of Medicine, Houston, Texas f. 1999-‐present: Courtesy Staff, Cardiology and Electrophysiology, Cypress Fairbanks Medical Center, Houston, Texas g. 1992-‐present: Active Staff, Cardiology and Electrophysiology, Christus St. Joseph Hospital, Houston, Texas h. 1992-‐present: Clinical Instructor of Medicine, Baylor College of Medicine, Houston, Texas D. Experience: 1. 1992-‐present: Managing Partner, Chief Executive Officer, Willowbrook Cardiovascular Associates, P.A., (formerly Houston Cardiac Electrophysiology Associates P.A.) E. Other Information: 1. Honors: a. 1986: Elected to Membership: Alpha Omega Alpha Medical Honor Society, University of Texas Southwestern Medical School b. 1981: Graduated Cum Laude, University of Houston 2. Professional Memberships and Societies: a. 1994: Heart Rhythm Society (formerly NASPE) b. 1993: Fellow, American College of Cardiology c. 1992: Harris County Medical Society d. 1990: Houston Electrophysiology Society 08/04/2010 3. II. e. 1989: American College of Physicians f. 1987: Texas Medical Association Licensures: a. H2637: Texas State Board of Medical Examiners b. BN1028655: Drug Enforcement Administration c. ROO66361: Texas Department of Public Safety d. 1952364788: National Provider Identifier e. C19785: Unique Physician Identifier Number Research Information A. Research Support: NIH Trials 1. MUSTT Mulitcenter Unsustained Tachycardia Trial a. 1995-‐1996 b. The Methodist Hospital c. Co-‐Investigator 2. SCD-‐HeFt (Sudden Cardiac Death in Heart Failure: Randomized Trial for the Prevention of Cardiac Death) a. 1997-‐1999 b. The Methodist Hospital, St. Luke’s Episcopal Hospital, Christus St. Joseph Hospital c. Co-‐Investigator 3. DAVID Trial (Dual Chamber and VVI Implantable Defibrillator Trial: A St. Jude Photon DR Model V-‐230HV Defibrillator) a. 2000-‐2001 b. The Methodist Hospital c. Principal Investigator B. Other Mulitcenter Clinical Trials: 1. Dos-‐Ranging Study of d-‐Satalol in Patients with Life-‐Threatening Ventricular Arrythmias a. 1992-‐1995 b. The Methodist Hospital c. Co-‐Investigator 2. Model 7212 PCD Pacer-‐Cardioverter-‐Defibrillator with Non-‐Thoractomy Lead Systems (Meth) Medtronic a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator 3. AVID Study Antiarrhythmics Versus Implantable Defibrillator a. Date: 1993-‐1998 b. The Methodist Hospital c. Co-‐Investigator 4. Efficacy and Safety of Oral d-‐Sotalol in Patients with Malignant Ventricular Arryhythmias and Implanted Cardioverter Defibrillators (ICDs) a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator 5. Randomized, Double-‐Blind Study of Orally Administered Dofetilide and Placebo in Patients with Implanted Arrythmias Control Device a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator 08/04/2010 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. Double Blind, Placebo-‐Controlled, Multicenter Study Evaluating the Efficacy and Safety of Different Oral Dose Levels of Dofetilide in the Prevention of Recurrence of Atrial Fibrillation/Flutter in Patients with Chronic Persistent Atrial Fibrillation/Flutter Converted Electrically or Pharmacologically to Sinus Rhythm a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator Model 7219D PCD Pace-‐Cardioverter-‐Defibrillator with Transvene and Epicardial Lead Systems a. 1993-‐1994 b. The Methodist Hospital c. Co-‐Investigator Open Label Safety Study of I.V. Amiodarone HCL in Patients with Life-‐Threatening Ventricular Tachycardia/Fibrillation a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator D-‐Sotatlol for the Treatment of Life-‐Threatening Refractory Ventricular Arrhythmias a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator Dose-‐Ranging Study of Oral Bidisomide vs. Placebo in Reducing the Recurrence of Symptomatic Atrial Fibrillation/Flutter and Paroxysmal Supraventricular Tachycardia a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator I.V. d-‐Sotalol Ventricular Tachycardia Termination Study a. 1993-‐1995 b. The Methodist Hospital c. Co-‐Investigator An Open Label, Long-‐Term Extension Study of Orally Administered Dofetilide in Patients with an Implanted Arrhythmia Control Device a. 1993-‐2000 b. The Methodist Hospital c. Co-‐Investigator Cadence TVL (Transvenous Lead) System a. 1993-‐1994 b. The Methodist Hospital c. Co-‐Investigator Model 7202 PCD Defibrillator with Transvene and Epicardial Lead Systems a. 1994-‐1995 b. The Methodist Hospital c. Co-‐Investigator Cadence V110 a. 1994-‐1995 b. The Methodist Hospital] c. Co-‐Investigator Jewel PCD 7219C Active Can System Model 7219C a. 1994-‐1995 b. The Methodist Hospital c. Co-‐Investigator A Ramdomized, Double-‐Blind, Parallel. Placebo-‐Controlled Evaluation of Orally Administered Dofetilide in Patients with Symptomatic Paroxysmal Atrial Fibrillation/Flutter (pAP, pAFL Or Paroxysmal Supraventricular Tachycardia (pSVT) 08/04/2010 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. a. 1994-‐1996 b. The Methodist Hospital c. Co-‐Investigator A Double-‐Blind, Placebo-‐Controlled Trial of the Efficacy and Safety of Two Doses of Oral Cordarone (Amiodarone HCL) in the Treatment of Patients with Refractory, Symptomatic, Paroxysmal Atrial Fibrillation/Flutter a. 1994-‐1997 b. The Methodist Hospital c. Co-‐Investigator Efficacy and Safety of d-‐Sotalol Versus Placebo in the Maintenance of Sinus Rhythm Following Pharmacologic or Electrical Cardioversion in Subjects in Sustained Atrial Fibrillation or Atrial Flutter a. 1995 b. The Methodist Hospital c. Co-‐Investigator Cadence V112 a. 1995 b. The Methodist Hospital c. Co-‐Investigator Candence TVL System Cadet V115 and V105 Pulse Generator Pectoral Placement a. 1995 b. The Methodist Hospital c. Co-‐Investigator Pectoral Evaluation of 1720 and 1725 Ventak PRxIII Endotak Lead System a. 1995-‐1996 b. The Methodist Hospital c. Co-‐Investigator Double-‐Blind, Placebo-‐Controlled, Multicenter Study Evaluating the Efficacy and Safety of Different Oral Dose Levels of Dofetilide in the Prevention of Recurrence of Atrial Fibrillation/Flutter in Patients with Chronic Persistent Atrial Fibrillation/Flutter Converted Electrically or Pharmacologically to Sinus Rhythm a. 1995-‐1996 b. The Methodist Hospital c. Co-‐Investigator Placebo-‐Controlled Evaluation of the Efficacy and Safety or Oral Sotalol in Patients with Life-‐Threatening Ventricular Arrhythmias and Implanted Cardioverter Defibrillators a. 1995-‐1997 b. The Methodist and St. Luke’s Episcopal Hospitals c. Co-‐Investigator Cadence TVL Systems Cadet High Voltage Can Converter Defibrillator Model V105AC-‐115AC a. 1996 b. The Methodist Hospital c. Co-‐Investigator Randomized, Double-‐Blind, Parallel, Placebo-‐Controlled Evaluation or Orally Administered Dofetilide in Subjects with Symptomatic Paroxysmal Atrial Fibrillation/Flutter (pAF, pAFL) a. 1996 b. Texas Arrhythmia Institute c. Co-‐Investigator TVL Defibrillation Lead System Clinical Investigation: Addition of Contour High Voltage Can Cardioverter/Defibrillator (Model V-‐135AC/V-‐145AC) a. 1996 b. The Methodist Hospital c. Co-‐Investigator 08/04/2010 28. Clinical Evaluation of the Res-‐Q II Defibrillation System a. 1996 b. The Methodist Hospital c. Co-‐Investigator 29. Model 7219PW Biphasic Tilt-‐Study: Custom Pulse Width Software a. 1996-‐1998 b. Texas Arrhythmia Institute c. Co-‐Investigator 30. Model 7221CX System Reduced Output Study (Micro Jewel), a. 1996-‐1998 b. Texas Arrhythmia Institute c. Co-‐Investigator 31. Constellation Multiple Electrode Mapping Catheter System: Study for Mapping and Pacing of a Heart Chamber During Electrophysiologic Evaluation a. 1996-‐1998 b. The Methodist Hospital c. Co-‐Investigator 32. Arginine Infusion During Upright Tilt Test a. 1996-‐1998 b. The Methodist Hospital c. Co-‐Investigator 33. Clinical Investigation for Res-‐Q Micron ACD System with Intervene Lead System a. 1996-‐1998 b. The Methodist Hospital c. Co-‐Investigator 34. Sentinel 2000 Implantable Defibrillation System U.S. Clinical Study a. 1996-‐1999 b. Texas Arrhythmia Institute c. Co-‐Investigator 35. Effect of Proximal vs. Distal Electrode Position on Ventricular DFT Using the Model 2394 External Cardioverter Defibrillator 36. 37. 38. 39. a. 1997 b. The Methodist Hospital c. Co-‐Investigator Randomized, Double-‐Blind, Placebo-‐Controlled Trial of Weekly Azithromycin on the Incidence of Coronary Artery Disease in Subjects with Evidence of Exposure to C Pneumoniae a. 1997 b. The Methodist Hospital c. Co-‐Investigator Ventak AVII DR Acute Tachy Study a. 1997-‐1998 b. The Methodist Hospital c. Co-‐Investigator Evaluation of Efficacy of Thermister Catheter with Radiofrequency Generator for Atrial Arrhythmias a. 1997-‐1998 b. The Methodist Hospital c. Co-‐ Investigator Ventritex Contour MD/Angstrom MD Clinical Investigation a. 1997-‐1998 b. The Methodist Hospital c. Co-‐Investigator 08/04/2010 40. Automatic Atrial Defibrillation System Clinical Study a. 1997-‐1999 b. The Methodist Hospital c. Co-‐Investigator 41. Model 7250 Arrhythmia Management Device Investigational Plan a. 1996-‐present b. The Methodist Hospital c. Co-‐ Investigator 42. Clinical Investigation of Res-‐Q DR 101-‐16 a. 1998-‐1999 b. The Methodist Hospital c. Co-‐Investigator 43. A Double-‐Blind, Placebo-‐Controlled, Randomized Clinical Trial of Slow Release Propafenone (Rythmol-‐SR) in the Prevention of Symptomatic Recurrences of Atrial Fibrillation a. 1998-‐2000 b. Texas Arrhythmia Institute c. Co-‐Investigator 44. Ventak CHF AICD Biventricular Pacing Study Investigational Plan a. 1998-‐present b. The Methodist Hospital c. Co-‐Investigator 45. A Prospective, Multinational, Multicenter, Double-‐Blind, Randomized, Active-‐Controlled Trial in Patients with Essential Hypertension to Compare the Effect of Valsartan 80 and 160mg, With or Without the Addition of Hydrocholorothiazide, Once Daily to that of Amlodipine 5 and 10mg Once Daily, With or Without the Addition of Hydrochlorothiazide, on Cardiovascular Morbidity and Mortality a. 1998-‐present b. Texas Arrhythmia Institute c. Co-‐Investigator 46. Radiofrequency Ablation of Accessory Pathways, AV Nodal Reentry Tachycardia and the AV Node for Rate Control Using the Bard Ablation System (St. Jude Medical Photon DR, Model V-‐230HV) 47. 48. 49. 50. 51. a. 1999-‐2000 b. Texas Arrhythmia Institute c. Co-‐Investigator Vigor CHF Biventricular Pacing in Congestive Heart Failure a. 1999-‐2000 b. Texas Arrhythmia Institute c. Co-‐Investigator Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure (Companion Study) a. 2001-‐2004 b. The Methodist Hospital c. Co-‐Investigator Resynchronization for Hemodynamic Treatment for Heart Failure Management (Rhythm ICD) St. Jude Medical a. 2002-‐2004 b. The Methodist Hospital c. Co-‐Investigator Resynchronization for Hemodynamic Treatment for Heart Failure Management Study (Rhythm ICD) Quicksite Left Heart Lead Model 1056K St. Jude Medical a. 2004-‐2005 b. The Methodist Hospital c. Co-‐Investigator Medtronic Ensure Study a. 2004-‐2006 08/04/2010 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. b. The Methodist Hospital c. Principal Investigator Guidant CRT-‐Renewal Registry Study a. 2004-‐2006 b. The Methodist Hospital c. Principal Investigator Medtronic Trends Study a. 2004-‐2007 b. The Methodist Hospital c. Principal Investigator Medtronic Reverse Study a. 2004-‐present b. The Methodist Hospital c. Principal Investigator Evaluation of the AT/AF Patient Notification Feature in Patients with a Bradycardia Indication for Pacing Study a. 2005 b. The Methodist Hospital c. Co-‐Investigator Resynchronization for Hemodynamic Treatment for Heart Failure Management Study (Rhythm ICD) Quicksite Left Heart Lead Model 1056T St. Jude Medical a. 2005-‐2006 b. The Methodist Hospital c. Co-‐Investigator Post Approval Study (St. Jude Medical) Principal Investigator (after 11/05) a. 2005-‐present b. The Methodist Hospital c. Co-‐Investigator AF Suppression/CRT-‐D Study (St. Jude Medical) Principal Investigator (after 11/05) a. 2005-‐2006 b. The Methodist Hospital c. Co-‐Investigator Victory IDE Pacemaker Study (St. Jude Medical) a. 2006-‐2007 b. The Methodist Hospital c. Principal Investigator Rethinq Study Resynchronization Therapy in Normal QRS (St. Jude Medical) a. 2006-‐2007 b. The Methodist Hospital c. Principal Investigator Cryocor-‐ 1CE-‐PAF (Cryotherapy vs. Anti-‐Arrhythmic MEDS for Treatment for Paroxysmal AFIB) a. 2006-‐present b. The Methodist Hospital c. Principal Investigator Connect Study ( Clinical evaluation Of remote Notification to reduce Time to Clinical Decision) Medtronic a. 2007-‐present b. The Methodist Hospital c. Principal Investigator Enable Study Pivotal Clinical Study of the Cardiofocus Endoscopic Ablation System for the Treatment of Symptomatic Atrial Fibrillation a. 2007-‐present 08/04/2010 b. Cardio Focus c. Co-‐Investigator 64. Determine Defibrillators To Reduce Risk by Magnetic Resonance Imaging Evaluation St. Jude Medical a. 2008-‐Present b. The Methodist Hospital c. Investigator 65. Optimum Lead Registry Study a. 2008-‐Present b. St. Jude Medical c. Investigator 66. Game Study a. 2008-‐present b. Medtronic c. Investigator 67. SLS a. 2009-‐Present b. Sponsored by Medtronic c. Investigator 68. Predicts study a. 2009-‐Present b. Sponsored by Medtronic and Lifevest c. Co-‐Investigator 69. Culturing Cardiac Rhythm Devices a. 2009 b. The Methodist Hospital c. Co-‐Investigator 70. Longitudinal Surveillance Registry of the ACUITY Spiral Lead a. 2009-‐ Present b. Sponsored by Boston Scientific c. Co-‐Investigator 71. C. Publications 1. Full Papers Nasir N Jr, Doyle TK, Wheeler SH, Pacifico A: Usefulness of Holter Monitoring in Predicting Efficacy of Amiodarone Therapy for Sustained Ventricular Tachycardia Associated with Coronary Artery Disease. a. American Journal of Cardiology b. 1994;73:554-‐558 Nasir N Jr, Taylor A, Doyle TK and Pacifico A: Evaluation of Intravenous Lidocaine for the Termination of Sustained Monomorphic Ventricular Tachycardia in Patients with Coronary Artery Disease With or Without Healed Myocardial Infarction. a. American Journal of Cardiology, b. 1994;74:1183-‐1186. The AVID Investigators: Antiarrhythmics Versus Implantable Defibrillators (AVID)-‐Rationale, Design, and Methods a. American Journal of Cardiology b. 1994;75:470-‐475 Nasir N Jr, Swarna US, Boahene KA, Doyle TK, Pacifico A: A Therapy of Sustained Ventricular Arrhythmias with Amiodarone: Prediction of Efficacy with Serial Electrophysiologic Studies 08/04/2010 a. Journal of Cardiovascular Pharmacology and Therapeutics b. 1996; I:123-‐132. Zaim S, Zaim B, Rottman J, Mendoza I, Nasir N Jr, Pacifico A: Characterization of Spontaneous Recurrent Ventricular Arrhythmias Detected by Electrogram-‐Storing Defibrillators in Sudden Cardiac Death Survivors with No Inducible Ventricular Arrhythmias at Baseline Electrophysiologic Testing a. American Heart Journal b. 1996;132:274-‐279. Pacifico A, Wheelan KR, Nasir N Jr, Wells PJ, Doyle TK, Johnson SA, Henry PD: Long-‐Term Follow-‐Up of Cardioverter-‐ Defibrillator Implanted Under Conscious Sedation in Prepectoral Subfascial Position a. Circulation b. 1997;95:946-‐950. Nasir N Jr, Pacifico A, Doyle TK, Earle NR, Hardage ML, Henry PD and the Cadence Investigators: Spontaneous Ventricular Tachycardia Treated by Antitachycardia Pacing a. American Journal of Cardiology b. 1997;79:820-‐822. Nasir N Jr, Cedillo-‐Salazar FR, Doyle TK, Henry PD, Pacifico A: Effect of Preexisting Epicardial Patch Electrodes on Defibrillation Thresholds of Unipolar Defibrillators a. Am J Cardiol b. 1997;79:1408-‐1409. Pacifico A, Cedillo-‐Salazar FR, Nasir N Jr, Doyle TK, Henry PD: Conscious Sedation with Combined Hypnotic Agents for Implantation of Implantable Cardioverter-‐Defibrillator a. Journal of the American College of Cardiology b. 1997;30:769-‐73. Kim SG, Hallstrom A, Love JC, Rosenberg Y, Powell J, Roth J, Brodsky M, Moore R, Wilkoff B, for the AVID Investigators: Comparison of Clinical Characteristics and Frequency of Implantable Defibrillator Use Between Randomized Patients in the Antiarrythmics vs. Implantable Defibrillators (AVID) Trial and Nonrandomized Registry Patients a. American Journal of Cardiology b. 1997;80:454-‐457. The AVID Investigators: A Comparison of Antiarrhythmic Drug Therapy With Implantable Defibrillators in Patients Resuscitated from Near-‐Fatal Ventricular Arrhythmias a. New England Journal of Medicine b. 1997;337:1576-‐1583. Flaker GG, Tummala R, Wilson J for Worldwide Jewel Investigators: Comparison of Right-‐ and Left-‐Sided Pectoral Implantation Parameters with the Jewel Active Can Cardiodefibrillator a. PACE b. 1998;21:447-‐451. Pacifico A, Johnson JW, Stanton MS, Steinhaus DM, Gabler R, Church T, Henry PD for the Jewel 7219D Investigators: Comparison of Results in Two Implantable Defibrillators a. American Journal of Cardiology b. 1998;82:875-‐880. Brooks MM, Jenkins LS, Schron EB, Steinberg JS, Cross JA, Paeth DS for the AVID Investigators: Quality of Life at Baseline: Is Assessment After Randomization Valid? a. Medical Care b. 1998;36:1515-‐1519. Shusterman V, Benhur A, Gottipaty V, Weiss R, Brode S, Schwartzman D, Anderson KP for the ESVEM Investigators: Autonomic Nervous System Activity and the Spontaneous Initiation of Ventricular Tachycardia 08/04/2010 a. Journal of the American College of Cardiology b. 1998;32:1891-‐1899. Anderson JL, Hallstrom AP, Epstein AE, Pinski SL, Rosenberg Y, Nora MO, Chilson D, Cannom DS, Moore R and the AVID Investigators: Design and Results of the Antiarrhythmics vs. Implantable Defibrillators (AVID) Registry a. Circulation b. 1999;99:1692-‐1699. Olshansky B, Hahn EA, Hartz VL, Prater SP, Mason JW and the ESVEM Investigators: Clinical Significance of Syncope in the Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) Trial a. American Heart Journal b. 1999;137:878-‐886. Pacifico A, Hohnloser SH, Williams JH, Tao B, Saksena S, Henry PD, Prystowsky EN for the d, I-‐Sotalol Implantable Cardioverter-‐Defibrillator Study Group: Prevention of Implantable Defibrillator Shocks by Treatment with Sotalol a. New England Journal of Medicine b. 1999;340:1855-‐1862. Pacifico A, Ferlic LL, Cedillo-‐Salazar F, Nasir N Jr, Doyle TK, Henry PD: Shocks as Predictors of Survival in Patients with Implantable Cardioverter-‐Defibrillators a. Journal of the American College of Cardiology b. 1999;34:204-‐210 Exner DV, Reiffel JA, Epstein AE, Ledingham R, Reiter MJ, Yao Q, Duff HJ, Follmann D, Schron E, Greene HL, Carlson MD, Brodsky MQA, Akiyama T, Baessler C, Anderson JL and the AVID Investigators: Beta-‐Blocker Use and Survival in Patients with Ventricular Fibrillation or Symptomatic Ventricular Tachycardia: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 1999:34:325-‐333. Epstein AE, Powell J, Yao Q, Ocampo C, Lancaster S, Rosenberg Y, Cannom DS, Herre JM, Greene HL, and the AVID Investigators: In-‐Hospital Versus Out-‐of-‐Hospital Presentation of Life-‐Threatening Ventricular Arrhythmias Predicts Survival: Results from the AVID Registry a. Journal of the American College of Cardiology b. 1999;34:1111-‐1116. The AVID Investigators: Causes of Death in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 1999;34: 1552-‐1559. Pinski SL, Yao Q, Epstein AE, Lancaster S, Greene HL, Pacifico A, Cook JR, Jadonath R, Marinchak RA and the AVID Investigators: Determinants of outcome in patients with sustained ventricular tachyarrhythmias: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Study a. American Heart Journal b. 2000;193:804-‐813 Connolly SJ, Hallstrom AP, Cappato R, Schron EB, Kuch K-‐H, Zipes DP, Greene HL, Boczor S, Domanski M, Follman D, Gent M, Roberts RS on behalf of the Investigators of the AVID, CASH and CIDS studies: Meta-‐analysis of the implantable cardioverter defibrillator secondary prevention trials a. European Heart Journal b. 2000;21:2071-‐2078. Raitt MH, Renfroe EG, Epstein AE, McAnulty JH, Mounsey P, Steinberg JS, Lancaster SE, Jadonath RL, Hallstrom AP for the AVID Investigators: "Stable" Ventricular Tachycardia Is Not a Benign Rhythm: Insights from the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. Circulation 08/04/2010 b. 2001;103:244-‐252. Exner DV, Pinski SL, Wyse G, Renfroe EG, Follmann D, Gold M, Beckman KJ, Coromilas J, Lancaster S, Hallstrom AP and the AVID Investigators: Electrical Storm Presages Nonsudden Death: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 2001;103:2066-‐2071. Hallstrom AP, McAnulty JH, Wilkoff BL, Follman D, Raitt MH, Carlson MD, Gillis AM, Shih H-‐ T, Powell JL, Duff H, Halperin BD and the Antiarrhythmics Versus Implantable Defibrillator (AVID) Trial Investigators: Patients at Lower Risk of Arrhythmia Recurrence: A Subgroup in Whom Implantable Defibrillators May Not Offer Benefit a. Journal of the American College of Cardiology b. 2001;37:1093-‐1099. Kron J, Herre J, Renfroe EG, Rizo-‐Patron C, Rain M, Halperin B, Gold M, Goldner B, Wathen M, Wilkoff B, Olarte A, Yao Q and the AVID Investigators: Lead-‐ and Device-‐Related Complications in the Antiarrhythmics Versus Implantable Defibrillators Trial a. American Heart Journal b. 2001;141:92-‐98 Exner DV, Sheldon RS, Pinski SL, Kron J, Hallstrom A and the AVID Investigators: Do baseline characteristics accurately discriminate between patients likely versus unlikely to benefit from implantable defibrillator therapy? a. American Heart Journal b. 2001;141:99-‐104. Hickey K, Curtis AB, Lancaster S, Larsen G, Warwick D, McAnulty J, Mitchell BL, and the AVID Investigators: Baseline factors predicting early resumption of driving after life-‐threatening arrhythmias in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. American Heart Journal b. 2001;142:99-‐104. Akiyama T, Powell JL, Mitchell LB Ehlert FA and Baessler C for the Antiarrhythmics versus Implantable Defibrillators Investigators: Resumption of Driving after Life-‐Threatening Ventricular Tachyarrhythmia a. New England Journal of Medicine b. 2001;345:91-‐397. Adler SW II, Wolpert C, Warman EN, Musley SK, Koehler JL, Euler DE for the Worldwide Jewel SF Investigators: Efficacy of Pacing Therapies for Treating Atrial Tachyarrhythmias in Patients With Ventricular Arrhythmias Receiving a Dual-‐ Chamber Implantable Cardioverter Defibrillator a. Circulation b. 2001;104:887-‐892. Friedman PA, Dijkman B, Warman EN, Zia A, Mehra R, Stanton MS, Hammill SC for the Worldwide Jewel SF Investigators: Atrial Therapies Reduce Atrial Arrhythmia Burden in Defibrillator Patients a. Circulation b. 2001;104:1023-‐1028. Hallstrom AP, Greene HL, Wilkoff BL, Zipes DP, Shron E, Ledingham RB and the Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators: Relationship Between Rehospitalization and Future Death in Patients Treated for Potentially Lethal Arrhythmia a. Journal of Cardiovascular Electrophysiology b. 2001;12:990-‐995. Steinberg JS, Beckman K, Greene HL, Marinchak R, Klein RC, Greer SG, Ehlert F, Foster P, Menchavez E, Raitt M, Wathen MS, Morris M, Hallstrom AP and the Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators: Follow-‐ Up of Patients with Unexplained Syncope and Inducible Ventricular Tachyarrhythmias: Analysis of the AVID Registry and an AVID Substudy a. Journal of Cardiovascular Electrophysiology b. 2001;12:996-‐1001. 08/04/2010 Steinberg JS, Martins J, Sadanandan S, Goldner B, Menchavez E, Domanski M, Russo A, Tullo N, Hallstrom AP and the AVID Investigators: Antiarrhythmic drug use in the implantable defibrillator arm of the Antiarrhythmics Versus Implantable Defibrillators (AVID) Study a. American Heart Journal b. 2001;142:520-‐529. Ehlert FA, Cannom DS, Renfroe EG, Green HL, Ledingham R, Mitchell LB, Anderson JL, Halperin BD, Herre JM, Luceri RM, Marinchak RA, Steinberg JS and the AVID Investigators: Comparison of dilated cardiomyopathy and coronary artery disease in patients with life-‐threatening ventricular arrhythmias: Differences in presentation and outcome in the AVID registry a. American Heart Journal b. 2001;142:816-‐822. Wyse DG, Love JC, Yao Q, Carlson MD, Cassidy P, Greene HL, Martins JB, Ocampo C, Raitt MH, Schron E, Stomato NJ, Olarte A and the AVID Investigators: Atrial Fibrillation: A Risk Factor for Increased Mortality-‐-‐ An AVID Registry Analysis a. Journal of Interventional Cardiac Electrophysiology b. 2001;5:267-‐273. Wyse DG, Friedman PL, Brodsky MA, Beckman KJ, Carlson MD, Curtis AB, Hallstrom AP, Raitt MH, Wilkoff BL, Greene HL for the AVID Investigators: Life-‐Threatening Ventricular Arrhythmias Due to Transient or Correctable Causes: High Risk for Death in Follow-‐Up a. Journal of the American College of Cardiology b. 2001;38:1718-‐1724. Schoels W, Swerdlow CD, Jung W, Stein KM, Seidl K, Haffajee CI for the Worldwide Jewel AF Investigators: Worldwide Clinical Experience with a New Dual-‐Chamber Implantable Cardioverter-‐Defibrillator System a. Journal of Cardiovascular Electrophysiology b. 12:521-‐528. Schron EB, Exner DV, Yao Q, Jenkins LS, Steinberg JS, Cook JR, Kutalek SP, Friedman PL, Bubien RS, Page RL, Powell J and the AVID Investigators: Quality of Life in the Antiarrhythmics Versus Implantable Defibrillators Trial a. Circulation b. 2002;105:589-‐594. Larsen G, Hallstrom A, McAnulty J, Pinkski S, Olarte A, Sullivan S, Brodsky M, Powell J, Marchant C, Jennings C, Akiyama T and the AVID Investigators: Cost-‐Effectiveness of the Implantable Cardioverter-‐Defibrillator Versus Antiarrhythmic Drugs in Survivors of Serious Ventricular Tachyarrhythmias: Results of the Antiarrhythmics Versus Implantable Defibrillators (AVID) Economic Analysis Substudy a. Circulation b. 2002;105:2049-‐2057. Cook JR, Rizo-‐Patron C, Curtis AB, Gillis AM, Bigger JT Jr, Kutalek SP, Coromilas J, Hoter BL, Powell J, Hallstrom AP for the AVID Investigators: Effect of Surgical Revascularization in Patients with Coronary Artery Disease and Ventricular Tachycardia or Fibrillation in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. American Heart Journal b. 2002;143:821-‐826. Brodsky MA, Mitchell LB, Halperin BD, Raitt MH, Hallstrom AP and the AVID Investigators: Prognostic Value of Baseline Electrophysiology Studies in Patients with Ventricular Tachyarrhythmias: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. American Heart Journal b. 2002;144:478-‐484. Renfroe EG, Heywood G, Foreman L, Schron E, Powell J, Baessler C, Warwick D, Morris M, Hallstrom A for the AVID Coordinators and Investigators: The End-‐of-‐Study Patient Survey: Methods Influencing Response Rate in the AVID Trial a. Controlled Clinical Trials b. 2002;23:521-‐533. 08/04/2010 Mitchell LB, Powell JL, Gillis AM, Kehl V, Hallstrom AP and the AVID Investigators: Are Lipid-‐Lowering Drugs Also Antiarrhythmic Drugs? An Analysis of the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 2003;42:81-‐87. Klein RC, Raitt MH, Wilkoff BL, Beckman KJ, Coromilas J, Wyse DG, Friedman PL, Martins JB, Epstein AE, Engelstein ED, Kim SG, Belco KM, Steinberg JS, Lancaster S, Greene HL and the AVID Investigators: Analysis of Implantable Cardioverter Defibrillator Therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of Cardiovascular Electrophysiology b. 2003;14:940-‐948. Evans RW, Atriham AR, and Nasir N: QT Prolongation with Migraine Medications a. Headache b. 2003:43:809-‐810. Klein RC, Schron EB, Graham Renfroe E, Hallstrom A, Kron J, Ocampo C, Leonen A, Tullo N, and the AVID Investigators: Factors Determining ICD Implantation in Drug Therapy of Antiarrhythmics Versus Implantable Defibrillators Trial a. PACE b. 2003;26:2235-‐2240. Kulasingam SL, Akiyama T, Mounsey P, Ledingham R, Hallstrom AP, and the AVID Investigators: Lower Observed Versus Expected (Based on U.S. Age and Gender Specific Rates) Survival in Patients Treated for Near Fatal Ventricular Arrhythmias a. PACE b. 2004; 27:230-‐234. Page RL, Zipes DP, Powell JL, Luceri RM, Gold MR, Peters R, Russo AM, Bigger JT, Sung RJ, McBurnie MA, and the AVID Investigators: Seasonal variation of mortality in The Antiarrhythmics Versus Implantable Defibrillators (AVID) study registry a. Heart Rhythm b. 2004;4:435-‐440. Nasir N and Rami TG. Cardiac Resynchronization Therapy (A Review and Future Directions) a. TMH Heart Journal b. 2007 Claude Daubert, MD, Michael R.Gold, MD, PHD, William T. Abraham, MD, PJD, Stefano GHio, MD, Christian Hassager, MD, PHD, Grahame Goode, MD, Tamas Szili-‐Torok, MD, PHD: Prevention of Disease Progression by Cardiac Resynchronization Therapy in Patients With Asymptomatic or Mildly Symptomatic Left Ventricular Dysfunction a. Journal of the American College of Cardiology b. 2009:54:1837-‐1846 2. Submitted for Publication a. Pacifico A, Doyle TK, Nasir N Jr, Henry PD: Coronary Vasospasm With Incessant Ventricular Fibrillation: A Case of "Reversible Dead Heart Syndrome." b. Pacifico A, Johnson JW, Nasir N Jr, Doyle TK, Arnold DJ, Gallinghouse GJ, Henry PD: Ventricular Defibrillation with Implantable Cardioverter-‐Defibrillator: Randomized Trial of Monophasic Versus Biphasic Waveforms. c. Puleo PR, Nasir N Jr, Wathen M, Pacifico A: Absence of Myocardial Necrosis in Patients Undergoing Discharge of an Implantable Cardioverter/Defibrillator . d. Pacifico A, Bhandari AK, Ilvento JP, Johnson EE, Josephson ME, Henry PHD, for The Reduced Output Study Investigators: Comparison of First VF Therapy Efficacy in Reduced vs. Full Output Implantable Defibrillators. 08/04/2010 3. e. Viola, George, Nasir, N Jr: Incubation Alone is Adequate for Culturing Cardiac Rhythm Management Devices ( JCM01354-‐09 Version-‐2) f. Nasir, N JR: Clinical Performance of the St. Judy Medical Riata Defibrillation Lead in a Large Patient Population (Journal of Cardiovascular Electrophysiology) Abstracts Nasir N, Wathen M, Pacifico A, Puleo PR: Absence of Myocardial Necrosis in Patients Undergoing Discharge of an Implantable Cardioverter/Defibrillator a. Circulation b. 1992;Supplement 86:I-‐59. Vybiral T, Hess KR, Knight C, Nasir N, Pacifico A: Noninvasive, Heart Rate Variability-‐Based Index Predicts Inducibility of Ventricular Tachycardia a. Journal of the American College of Cardiology b. 1993;21:459A. Pacifico A, Nasir N Jr, Doyle T, Wheeler SH, Hardage M, Rodriguez I, Lawrie G, Cadence Investigators: Safety and Efficacy of Antitachycardia Pacing with a New Third Generation Implantable Cardioverter Defibrillator a. European Heart Journal b. 1993; 14:409. Pacifico A, Nasir N Jr, Doyle TK, Wheeler SH, Lawrie G, Hardage M, and the Cadence Investigators: Efficacy of a New Implantable Cardiac Defibrillator in Patients with Elevated Defibrillation Thresholds a. Circulation b. 1993;88:Suppl:I-‐113. Pacifico A, Nasir N Jr, Doyle TK, Wheeler SH, Hardage M, Rodriguez IM, Lawrie GM, Cadence Investigators: Safety and Efficacy of Antitachycardia Pacing with a New Third-‐ Generation Implantable Cardioverter Defibrillator a. Circulation b. 1993;88:Suppl:I-‐155. Pacifico A, Nasir N Jr, Doyle TK, Wheeler SH, Lawrie G, Hardage M, and the Cadence Investigators: Incidence of Appropriate Implantable Cardiac Defibrillator Therapy in Non-‐Inducible Survivors of Sudden Cardiac Death a. Circulation b. 1993;88:Suppl:I-‐482. Pacifico A, Nasir N Jr, Doyle TK, Rodriguez IM, Wheelan KD, Wells P,Seton M: Initial Experience with the Medtronic PCD 7219D a. Circulation b. 1994;90:I-‐123. Pacifico A, Nasir N Jr, Doyle TK, Rodriguez IM, Wheelan KD, Wells P, Seton M: Technique of Cath Lab ICD Implantation Without General Anesthesia a. Circulation b. 1994;90:I-‐498 08/04/2010 The AVID Investigators: Patient Enrollment in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Study-‐ Pilot Phase a. PACE b. 1995;18:799 Bardy GH, Yee R, and the International Active Can Investigators: Worldwide Experience with the Jewel 7219C Unipolar, Single Lead Active Can Implantable Pacer-‐Cardioverter-‐ Defibrillator a. PACE b. 1995;18:806 Mattioni TA and Riggio DW for the Cadence TVL Investigators: Clinical Experience with a New Non-‐Thoracotomy Cardioverter-‐Defibrillator Lead System a. PACE b. 1995; 18:807 Gabler R, Kavaney D, Sakun V, Church T and the Jewel Investigators: Worldwide Clinical Experience with a New Biphasic Implantable Cardioverter/ Defibrillator a. PACE b. 1995:18:826. LeFeuvre C, Klein GJ, Sakun V, Sheahan R, Krahn A, Yee R for the Jewel Investigators: Is Predischarge ICD Defibrillation Threshold Testing Necessary? a. PACE b. 1995;18:827 The AVID Investigators: Characteristics of Patients Enrolled in the Pilot Phase of the Antiarrhythmics Versus Implantable Defibrillators (AVID) Study 1. PACE 2. 1995;18:900 Kavaney D, Church T, Gabler R, Sakun V and the Jewel Investigators: How Much Better is a Biphasic Compared to a Monophasic Defibrillation Waveform? a. PACE b. 1995;18:946. Zaim S, Zaim B, Rottman J, Mendoza I, Nasir N Jr, Pacifico A and the Cadence Investigators: Sudden Cardiac Death Survivors with Only Ventricular Fibrillation Induction at Baseline Electrophysiologic Testing: Subsequent Ventricular Tachyarrhythmias a. PACE b. 1995;18:1118. Kim SG, Love J, Rosenberg Y, Powell J and the AVID Investigators: Therapy in the AVID (Antiarrhythmics Versus Implantable Defibrillators) Trial is Not Significantly Different from Current Clinical Practice a. Circulation b. 1995;92:I-‐782. Curtis AB, Klein R, Nath S, Pinski SL, Epstein AE, Hallstrom A, Renfroe E for the AVID Investigators: Influence of Patient Characteristics in the Selection of Patients for Defibrillator Implantation: The AVID (Antiarrhythmics Vs. Implantable Defibrillators) Registry a. Circulation b. 1995;92:I-‐782. Domanski M, Saksena S, Schron E, Kutalek SP, Wyse G, Hallstrom A for the AVID Investigators: Clinical, Educational and Socio-‐Economic Profile of Patients with Malignant Ventricular Arrhythmias in 1993-‐95: A Prospective Study a. PACE b. 1996;19:603 08/04/2010 Pacifico A, Nasir N Jr, Doyle TK, Johnson SA, Wheelan KR, Wells PJ, Henry PD: Long-‐Term Follow-‐Up of 149 Patients Treated With Nonthoracotomy Cardioverter-‐ Defibrillator in Prepectoral Position. a. PACE b. 1996;19:733. The AVID Investigators: Bradyarrhythmias with Antiarrhythmia Drugs in VT/VF Survivors in the AVID Trial a. Circulation b. 1996;94:I-‐#1431. Kron J, Yao Q, Olarte A, Halperin BD, Raitt M, Renfroe E, Herre JM, Klevan LR, Wilkoff BL, Goldner BB, Rizo-‐ Patron C, for the AVID Investigators: Lead Complications with Nonthoracotomy Defibrillation Lead Systems in the AVID Study a. Circulation b. 1997;96:I-‐77, #421. Larsen GC, McAnulty JH, Hallstrom A, Merchant C, Shein M, Akiyama T, Brodsky M, Baessler C, Pinski SL, Jennings CA, Morris M and the AVID Investigators: Hospitalization Charges in the Antiarrhythmics versus Implantable Defibrillators (AVID) Trial: the AVID Economic Analysis Study a. Circulation b. 1997;96:I-‐77, #424. Wilkoff BL, Shih H-‐T, Friedman PL, Page RL, Klein RC, Dalamagas H, Nora M, Larsen GC, Baessler C, Morris M, Jennings C and the AVID Investigators: Multivariate Predictors of Hospital Length of Stay in Patients with Severe Ventricular Arrhythmias: Antiarrhythmics versus Implantable Defibrillators Registry Study a. Circulation b. 1997;96:I-‐78, #425. Halperin BD, Brodsky MA, Lancaster S, Raitt M, Kron J, Akiyama T, Englestein ED, Jadonath R, Mitchell LB, Daubert JP, and the AVID Investigators: Prognostic Value of Baseline Electrophysiology Studies-‐ The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1997;96:I-‐334, #1865 Beckman KJ, Klein RC, Page RL, Love JC, Follmann D, Moore RT, Kandrac J, Cannom DS, Duff HJ, Hallstrom A and the AVID Investigators: Effect of Antiarrhythmic Therapy on Survival in Patients with Ventricular Tachycardia or Fibrillation in the Antiarrhythmics vs. Implantable Defibrillators (AVID) Trial Registry a. Circulation b. 1997;96:I-‐335, #1868. Jenkins LS, Steinberg JS, Kutalek SP, Cook JR, Schron EB, Friedman PL, Cross C, Bosworth-‐Farrell S, Roth J, Yao Q and the AVID Investigators: Quality of Life in Patients Enrolled in the Antiarrhythmics versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1997;96:I-‐439, #2451. Pacifico A, Cedillo-‐Salazar FR, Doyle TK, Nasir N Jr, Ferlic LL, Henry PD: Multiple Consecutive Shocks: An Important Predictor of Long-‐Term Survival in Patients with Implantable Defibrillators. a. Circulation b. 1997;96:I-‐579, #3240. Steinberg JS, Ehlert FA, Cannom DS, Marinchak RA, Halperin BD, Herre JM, Gonzalez MD, Anderson J, Mitchell LB, Luceri R, Ledingham R, Renfroe EO for the AVID Investigators: Dilated Cardiomyopathy vs. Coronary Artery 08/04/2010 Disease in Patients with VT/VF: Differences in Presentation and Outcome in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. Circulation b. 1997;96:I-‐715, #4012. Friedman PL, Yao Q, Buxton AE, Engelstein ED, Schron EB, Bishop V, Firth B, Dalamagas H, Flynn D, Torres VI, Coromilas J and the AVID Investigators: Effect of Race on Treatment Selection in Patients with Life-‐ Threatening Ventricular Arrhythmias a. Circulation b. 1997;96:I-‐719, #4032. Engelstein ED, Friedman PL, Yao Q, Coromilas J, Beckman KJ, Buxton AE, Flynn D, Firth B, Dalamagas H, Ledingham R, Schron EB and the AVID Investigators: Gender Differences in Patients with Life-‐Threatening Ventricular Arrhythmias: Impact on Treatment and Survival in the Antiarrhythmics versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1997;96:1-‐720, #4036. Kim SG, Love JC, Rosenberg Y, Powell J, Brodsky M, Moore R and the AVID Investigators: The Results of the Antiarrhythmic Versus Implantable Defibrillators (AVID) Trial Can Be Applied to the General Ventricular Tachycardia/Ventricular Fibrillation Patient Population a. Journal of the American College of Cardiology b. 1998;31:358A, #875-‐5. Pinski SL, Page RL, Mounsey JP, Shih H-‐T, Lancaster S, Graham-‐Renfroe E, Yao Q and the AVID Investigators: Absence of Prevalence-‐Incidence Bias in the Antiarrhythmic vs. Implantable Defibrillator (AVID) Trial a. Journal of the American College of Cardiology b. 1998;31:121A, #1047-‐177 Anderson JL, and the AVID Investigators: Long-‐Term Survival in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. Journal of the American College of Cardiology b. 1998;31:160A, #1073-‐175 Shih H-‐T, Wyse DG, Rizo-‐Patron C, Stamato NJ, Daubert JP, Lancaster S, Renfroe EG, Connors N, Pacifico A, Crevey B, Jennings C, Whiting D, Yao Q and the AVID Investigators: Regional Differences in Utilization of Implantable Cardioverter/ Defibrillators-‐ An Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry Study a. Journal of the American College of Cardiology b. 1998;31:435A, #1176-‐175. Epstein AE, Graham-‐Renfroe E, Powell J, Kim CH, Ocampo C, Cannom DS, Herre JM, Friedman PL, Yao Q, Lancaster S, Rosenberg Y and the AVID Investigators: In-‐Hospital vs. Out-‐of-‐Hospital Presentation of Life-‐ Threatening Ventricular Arrhythmia Predicts Survival-‐-‐ Results From the Antiarrhythmics vs. Implantable Defibrillators (AVID) Registry a. Journal of the American College of Cardiology b. 1998;31:435A, #1176-‐178 Steinberg JS, Martins JB, Domanski M, Foster P, Goldner B, Greene HL, Menchavez-‐Tan E, Rizo-‐Patron C, Russo A, Tullo N, Moore R, Hallstrom A and the AVID Investigators: Antiarrhythmic Drug Use in the Implantable Defibrillator Arm of the Antiarrhythmics vs. Implantable Defibrillators (AVID) Study a. Journal of the American College of Cardiology 08/04/2010 b. 1998;31:514A, #1229-‐177 Swerdlow CD, Sheth NV, Olson WH for the Worldwide Jewel AF Investigators: Clinical Performance of a Pattern-‐Based, Dual-‐Chamber Algorithm for Discrimination of Ventricular from Supraventricular Arrhythmias a. PACE b. 1998;21:800, #43 Lieberman RA, Bates A, for the Worldwide Jewel AF Investigators: Insights into Lead Configuration and Initial Atrial Defibrillation Thresholds in a Dual-‐Chamber Active Can Defibrillator a. PACE b. 1998;21:806, #68 Swerdlow CD, Sheth NV, Gunderson BD, Olson WH for the Worldwide Jewel AF Investigators: Rapid, Continuous Detection of Atrial Fibrillation by a Dual-‐Chamber Implantable Cardioverter-‐Defibrillator a. PACE b. 1998;21:853, #255 Lerman B, Stein K, Markowitz S for the Worldwide 7250 Clinical Investigators: Worldwide Clinical Experience with the Model 7250 Jewel AF Dual-‐Chamber Arrhythmia Management Device a. PACE b. 1998;21:872,#329. Pacifico A, Trainor K, Nasir N Jr, Doyle TK, Arnold DJ, Gallinghouse GJ Jr, Henry PD, Gorman P: Initial Clinical Experience with the Sulzer Intermedics Iridium Oxide Defibrillation Coil and the Res-‐Q Micron Lead-‐to-‐Can Defibrillator a. Arch Coeur Vaisseaux b. 1998;182, #97-‐1 Klein RC, Raitt MH, Greene HL, Beckman K, Coromilas J, Wilkoff BL, Wyse DG, Friedman PL, Martins JB, Epstein AE, Engelstein ED, and the AVID Study Investigators: Analysis of Implantable Cardioverter Defibrillator Therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1998:98:I-‐191, #988 Coromilas J, Anderson J, Hallstrom A, Klein RC, Halperin BD, Marinchak R, Greene HL, Sheldon RS, Brodsky MA, McAnulty J, Moore R, the AVID Investigators: Treatment and Outcome in Patients with "Normal Hearts" in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. Circulation b. 1998:98:I-‐191, #990 Chien WW, Kutalek SP, Moore R, Yao Q, Powell J, Daubert JP, Reiffel J, Reiter M, Belco K, the AVID Investigators: The Antiarrhythmics Versus Implantable Defibrillators Trial Exclusions Differ by Types of Index Arrhythmias a. Circulation b. 1998;98:I-‐290. #1512 Pacifico A, Nasir N Jr, Doyle TK, Arnold DJ, Gallinghouse GJ Jr, Henry PD: Rarity of Myocardial Ischemia After Appropriate Defibrillatory Shocks for Fast Ventricular Tachyarrhythmias: Evidence Against the Plaque Rupture Theory of Sudden Cardiac Death. a. Circulation 08/04/2010 b. 1998;98:I-‐290, #1513 Exner DV, Epstein AE, Reiter MJ, Yao Q, Ledingham R, Reiffel JA, Brodsky M, Akiyama T, Schron E, Follmann D, Anderson J for the AVID Investigators: Beta-‐Blocker Use and Mortality in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Cohort a. Circulation b. 1998;98:I-‐494, #2598 Renfroe EG, Raitt MH, McAnulty J, Epstein AE, Carlson MD, Powell JL, Lancaster S, Hallstrom A and the AVID Study Investigators: "Stable" Ventricular Tachycardia May Not Be Benign: Insights from the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry a. Circulation b. 1998;98:I-‐494. #2599 Raitt MH, Klein RC, Greene HL, Wilkoff BL, Wyse DG, Beckman KJ, Martins JB, Kim SG, Epstein AE, Engelstein ED, Friedman PL, AVID Investigators: Arrhythmia Recurrence in Patients Presenting With Ventricular Fibrillation Compared to Ventricular Tachycardia in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1998;98:I-‐494. #2600 Pratt CM, Greene HL, Anderson JL, Cobb LA, Ehlert F, Epstein AE, Flynn D, Kim S, Richardson DW, Schron E, Moore R, and the AVID Investigators: Causes of Death in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1998;98:I-‐494, #2602 Friedman PL, Brodsky MA, Yao Q, Lancaster SE, Greene HL, Beckman K, Carlson MD, Curtis AB, Raitt MH, Wilkoff BL and the AVID Investigators: Survival After Ventricular Arrhythmias Due to A Transient, Correctable Cause in the Antiarrhythmics vs. Implantable Defibrillators (AVID) Trial Registry a. Circulation b. 1998;98:I-‐495, #2604 Cook JR, Rizo-‐Patron C, Domanski M, Kim SG, Coromilas J, Curtis AB, Kutalek S, Gillis AM, Berns E, Powell J, Hallstrom A for the AVID Investigators: The Effect of Myocardial Revascularization in Patients with VT/VF and Coronary Artery Disease: Relationship to Outcome in the Antiarrhythmics versus Implantable Defibrillators (AVID) Registry a. Circulation b. 1998;98:I-‐496,#2608 Wyse DG, Love JC, Yao Q, Carlson MD, Cassidy P, Greene HL, Martins JB, Ocampo C, Raitt MH, Schron E, Stamato NJ and the AVID Investigators: A Risk Factor for Increased Mortality in Patients with Ventricular Tachyarrhythmias-‐ An AVID Registry Analysis a. Circulation b. 1998;98:I-‐633,#3329 c. Klein RC, Schron E, Renfroe EG, Rizo-‐Patron C, Tullo N, Lancaster S, the AVID Investigators: Factors Determining Implantation of Defibrillators Following Trial Termination in Patients Randomized to Drug Therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 1999;33:114A, #801-‐1 08/04/2010 Hohnloser SH, Pacifico A, Williams JH, Prystowsky EN for the Sotalol-‐ICD Investigators: Efficacy and Safety of Oral d, I-‐Sotalol in Patients with Implanted Defibrillators: Results of a Prospective, Double-‐Blind, Randomized, Placebo-‐Controlled Multicenter Trial a. Journal of the American College of Cardiology b. 1999;33:115A,#801-‐3 Steinberg JS, Tullo NG, Anderson JL, Beckman K, Crevey BJ, Friedman PL, Greene HL, Larsen GC, Rizo-‐Patron C, Russo AM, Zipes DP, Moore RT, Hallstrom AP, the AVID Investigators: Relationship of Coronary Perfusion and Stensosis to Arrhythmic Events in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 1999;33:119A, #1085-‐182 Martins J, Herre J, Gillis A, Marinchak R, Carlson MD, Beckman K, Olarte A, Powell J, Yao Q, the AVID Investigators: Does Type of Prior Revascularization Predict Mode of Presentation with Malignant Ventricular Arrhythmias a. Journal of the American College of Cardiology b. 1999;33:120A,#1085-‐183 Jodonath R, Singer I, Payne V, Crevey B, Suri R, Omar A, Pacifico A, Rizo-‐Patron C, Kutalek S, Goldner B, Harari D and the Intervene & Endotak Clinical Trial Investigators: Is a Dual-‐Coil Defibrillator Lead Necessary? a. PACE b. 1999;22:700, #6 McAnulty J, Wilkoff B, Akiyama T, Raitt M, Renfroe EG, Hallstrom A, Kron J, and the AVID Investigators: Bradyarrhythmias-‐ a Possible Cause of Death in Patients on Antiarrhythmic Drugs in the AVID Trial a. PACE b. 1999;22:706, #28 Page RL, Luceri RM, Gold MR, Peters R, Follmann DA, Russo AM, Powell JL, Bigger Jr JT, Kim CH, Sung RJ, Zipes DP, Yao Q, Lancaster S and the AVID Investigators: Patterns of Mortality in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Study Registry: Evidence for Increased Mortality Related to the Winter Holidays a. PACE b. 1999;22:712, #53 Marinchak RA, Jadonath R, Renfroe EG, Martins J, Page RL, Reiffel JA, Menchavez E, Russo R, Zilo P, Ledingham R and the AVID Investigators: Efficacy of and Tolerance to Sotalol and Amiodarone in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. PACE b. 1999;22:770, #280 Anderson KP, Shusterman V, Beigel A, Aysin B, Brode S, Gottipaty V and Weiss R for the ESVEM Investigators: Changes in Ventricular Repolarization Preceding the Onset of Spontaneous Sustained Ventricular Tachycardia a. PACE b. 1999;22:837, #548 Shusterman V, Aysin B, Flanigan S, Usiene I, Brode S, Gottipaty V, Weiss R, Anderson KP for the ESVEM Investigators: Intermediate-‐Term Predictors of Ventricular Tachyarrhythmias a. PACE b. 1999;22:837, #549 08/04/2010 Shusterman V, Aysin B, Chaparro LF, Grave I, Brode S, Gottipaty V, Weiss R, Anderson KP for the ESVEM Investigators: On-‐Line Prediction of Ventricular Tachyarrhythmias Using Short-‐Term RR-‐Interval Perturbations: Comparative Analysis of Different Signal Processing Techniques a. PACE b. 1999;22:837, #550 Exner DV, Reiffel JA, Epstein AE, Ledingham R, Reiter MJ, Yao Q, Duff HJ, Follmann D, Schron E, Green HL, Carlson MD, Brodsky MA, Akiyama T, Baessler C, Anderson JL and the AVID Investigators: Beta-‐Blocker Use and Survival in Patients with Ventricular Fibrillation or Symptomatic Ventricular Tachycardia: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Journal of the American College of Cardiology b. 1999;34:325-‐333 Exner DV, Lancaster SE, Pinski SL, Graham-‐Renfroe E, Wyse DG, Coromilas J, Follman D, Gold MR, Beckman KJ, Karagounis L, Hallstrom A, and the AVID Investigators: Electrical Storm is an Independent Risk Factor for Early Death: The Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1999;100:18:I-‐366,#921 Steinberg JS, Vloka ME, Yao Q, Shron E, Dorian P, Powell J, and the AVID Investigators: Relationship of Baseline Quality of Life Scores to Long-‐Term Survival in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial a. Circulation b. 1999; 100:18:I-‐367,#1925 McAnulty JH, Hallstrom A, Wilkoff BL, Follmann D, Shih T, Carlson M, Powell J and the AVID Investigators: The Low Arrhythmia Frequency Sextile: A Subgroup That Doesn't Need an Implanted Defibrillator a. Circulation b. 1999;100:I-‐367,#1926 4. Tullo NG, Stamato NJ, Reiter M, Reiffel J, Goldner B, Bigger JT, Rosenberg Y, Whiting D, Graham-‐Renfroe E, Jedingham RB, Hallstrong A, and the AVID Investigators: Prior Antiarrhythmic Drug Use Does Not Predict Survival but Does Affect Impact of Cardioverter-‐Defibrillators: An Analysis of the Antiarrhythmics Versus Implantable Defibrillators (AVID) Study a. Circulation b. 1999;100:18:I-‐570,#3004. Poster Presentations Nasir, Nadim: Absence of Myocardial Necrosis Following Cardioversion by Implantable Cardioverter/Defibrillator Discharge a. American Heart Assn, New Orleans b. November 16-‐19, 1992. Pacifico A, Nasir N, Doyle TK, Rodriguez IM, Wheelan KD, Wells P, Seton M: Technique of Cath Lab ICD Implantation Without General Anesthesia a. American Heart Assn, Dallas, Texas b. November 14-‐17, 1994 Nadim Nasir Jr., MD, FACC, May Achi, Pharm D, BCPS, Janet Hudkins, RN, ACNP: Thrombophlebitis Associated with Peripheral Amoidarone Infusions a. The Methodist Hospital, Houston, Texas • Pending Additional Publications and Research Studies 08/04/2010