Download The Uplink Issue 35 Citric Acid Cycle Notes

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NAD = Nicotinamide adenine dinucleotide (B-3 / Niacinamide coenzyme form)
FAD = Flavin adenine dinucleotide (B-2 / Riboflavin coenzyme form)
RAPID SCREENING: If CO2 (rebreathing) strengthens, check:
"CAC Factors:" [Thiamine (B-1), Riboflavin (B-2), Niacinamide (B-3), Manganese, Pantothenic Acid (B-5),
Lipoic Acid (Thioctic Acid)]; "B" and "G."
If none of these strengthen, check biotin (or rarely, magnesium or phosphorus.)
Note: B-6 or Pyridoxal-5-phosphate will work when no CAC nutrient is found.
In the presence of immune system stress and/or toxicity, cytokines such as IL-2 (Interleukin-2) and TNF (tumor
necrosis factor) induce the production of nitric oxide (NO). NO deactivates aconitase enzyme in the CAC and
uncouples the process of oxidative phosphorylation. This leads to lowered ATP production and a build up of
lactic acid, pyruvic acid, and other organic acids which are CAC intermediaries. These can be measured by
urine organic acid profiles.
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