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Insulin Deficiency Consequences Intracellular Glucose Deficienccy Deficient A.T.P. production in C.A.C. Plasma Glucose Elevated Osmotic Diuresis Counter-regulatory Hormones stimulate Gluconeogenesis Protein catabolism Electrolyte loss in urine Fat catabolism Ketosis Polyuria Weakness Coma Wasting Acidosis Dehydration Thirst