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CONSTRICTIVE PERICARDITIS Division of Cardiology Department of Internal Medicine Tae Kyung Yu Pericardial Disease Acute pericarditis Chronic relapsing pericarditis Constrictive pericarditis Cardiac tamponade Constrictive Pericarditis Acute pericarditis나 chronic pericardial effusion이 healing 되면서 granulation tissue 가 형성되어 pericardium이 두꺼워지고 fibrosis, calcification되어 cardiac filling에 장애 를 초래 Early diastole 시에는 ventricular filling에 장애 를 받지 않으나 이후에 pericardium의 elastic limit에 도달하여 심한 ventricular filling의 장애 가 특징 Constrictive Pericarditis의 원인 NEJM 2004;350:5;469-75 Constrictive Pericarditis의 원인 JAMA 2004;43:271-5 Constrictive Pericarditis Rarely after an episode of acute idiopathic pericarditis More likely after subacute pericarditis with effusion that evolve over several weeks More frequent after purulent bacterial or tuberculous pericarditis Clinical manifestations Lung : pleural effusion Heart : diastolic pericardial knock Abdomen : ascites, pulsatile liver Extremities : peripheral edema Jugular veins Prominent X and Y descent (M shaped contour) Kussmaul’s sign Diagnosis Cardiac catheterization Square root sign or dip and plateau pattern : rapid early diastolic filling of the ventricle, followed by lack of additional filling due to compression in mid and late diastole Echocardiography Echocardiographic findings M-mode and 2D Thickened pericardium Abnormal ventricular septal motion (respiratory septal shift Rt-> Lt. in inspiration, Lt->Rt in expiration) Flattening of the LV posterior wall during diastole Respiratory variation in ventricular size Dialted IVC Thickened Pericardium Dialted IVC JAMA 2004;43:271-5 Echocardiographic findings Two hemodynamic characteristics 1) Dissociation between intrathoracic and intracardic pr 2) Exaggerated ventricular interdependence in diastolic filling Echocardiographic findings Doppler echo Respiratory variation of 25% or greater in mitral E velocity Increased diastolic flow reversal with expiration in the hepatic flow Increased mitral annulus velocity Respiratory variation of 25% or greater in mitral E velocity ↑ diastolic flow reversal with expiration in the hepatic flow JAMA 2004;43:271-5