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Cellular Neuroscience (NB&B 207) - Winter 2017
M,W,F 10:30 – 11:50 : 2246 McGaugh Hall
Instructors – Ian Parker (course coordinator) [email protected], Raju Metherate [email protected],
Katumi Sumikawa [email protected]
Grading Policy: Grades will be based on exams and take-home quizzes
Text: There is no assigned text. Handouts and readings will be assigned during lectures. Purves et al.
"Neuroscience" can be used for introductory material. The 2nd edition is available free at
http://www.ncbi.nlm.nih.gov/books/NBK11103/
Date
Topic
Instructor
Section #1 Ion channels and neuronal electrophysiology
Jan 9
Jan 11
Jan 13
Jan 16
Jan 18
Jan 20
Jan 23
Jan 25
Jan 27
Jan 30
Feb 1
Introduction to electrical concepts
Passive electrical properties of membranes
Membrane potential, Nernst, Goldman equations
Martin Luther King Holiday
Ion channels – electrophysiology, patch clamping
Ion channels – voltage-gated channels
Ion channels – ligand-gated channels
Action potentials
The Hodgkin & Huxley Axon
Discussion/review session
Chemical synapses, quantal transmission
IP
IP
IP
IP
IP
IP
RM
RM
IP/RM
RM
Section #2 Synaptic transmission
Feb 3
Feb 6
Feb 8
Feb 10
Feb 13
Feb 15
Feb 17
Feb 20
Feb 22
Feb 24
Feb 27
March 1
March 3
EXAM #1 (not including material of Feb 1 lecture)
Ca2+ and neurotransmitter release, EPSPs and IPSPs
Slow synaptic potentials
Neurotransmitters
Molecular mechanisms of vesicular release
Neurotransmitter receptors
Synaptic integration
Presidents Day Holiday
Second messenger pathways #1
Second messenger pathways #2
Synaptic plasticity
Discussion/review
EXAM #2 (during lecture period – before lab class)
RM
RM
KS
KS
KS
RM
KS
KS
KS
KS/RM
Cellular Neuroscience Lab (207L)
March 6 – March 16 Lab class – full time every day
I.P. / R.M.
March 16 Student presentations for lab class
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