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Cellular Neuroscience (NB&B 207) - Winter 2017 M,W,F 10:30 – 11:50 : 2246 McGaugh Hall Instructors – Ian Parker (course coordinator) [email protected], Raju Metherate [email protected], Katumi Sumikawa [email protected] Grading Policy: Grades will be based on exams and take-home quizzes Text: There is no assigned text. Handouts and readings will be assigned during lectures. Purves et al. "Neuroscience" can be used for introductory material. The 2nd edition is available free at http://www.ncbi.nlm.nih.gov/books/NBK11103/ Date Topic Instructor Section #1 Ion channels and neuronal electrophysiology Jan 9 Jan 11 Jan 13 Jan 16 Jan 18 Jan 20 Jan 23 Jan 25 Jan 27 Jan 30 Feb 1 Introduction to electrical concepts Passive electrical properties of membranes Membrane potential, Nernst, Goldman equations Martin Luther King Holiday Ion channels – electrophysiology, patch clamping Ion channels – voltage-gated channels Ion channels – ligand-gated channels Action potentials The Hodgkin & Huxley Axon Discussion/review session Chemical synapses, quantal transmission IP IP IP IP IP IP RM RM IP/RM RM Section #2 Synaptic transmission Feb 3 Feb 6 Feb 8 Feb 10 Feb 13 Feb 15 Feb 17 Feb 20 Feb 22 Feb 24 Feb 27 March 1 March 3 EXAM #1 (not including material of Feb 1 lecture) Ca2+ and neurotransmitter release, EPSPs and IPSPs Slow synaptic potentials Neurotransmitters Molecular mechanisms of vesicular release Neurotransmitter receptors Synaptic integration Presidents Day Holiday Second messenger pathways #1 Second messenger pathways #2 Synaptic plasticity Discussion/review EXAM #2 (during lecture period – before lab class) RM RM KS KS KS RM KS KS KS KS/RM Cellular Neuroscience Lab (207L) March 6 – March 16 Lab class – full time every day I.P. / R.M. March 16 Student presentations for lab class