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Tutorial_pharamcodynamics
1. What is the relationship between molecular dynamics and molecular kinetics
(pharmacodynamics and pharmacokinetics)?
2. Can the kidney perform as site of absorption, distribution, metabolism and excretion?
how?
3. Draw a scheme represent a metabolic pathway and how a drug can affect the enzyme
which catalyzes that pathway by a dissociation constant.
4. Explain by drawing the idea behind drug’s effect and side effect from
pharmacodynamics point of view.
5. What is the therapeutic index?
6. What is the relationship between therapeutic index and each of ki and kside?
7. Give three examples for drug groups which have low therapeutic index.
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