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Chapter 8: DNA & RNA DNA: deoxyribonucleic acid chromosomes are made of DNA Double helix shape Made of units called nucleotides Three parts of a nucleotide: Sugar Phosphate Base Adenine Thymine Guanine Cytosine DNA double helix Base Pairing Rule: Adenine-Thymine A-T Cytosine-Guanine C-G DNA Processes: Replication - make a copy of itself Protein Synthesis - make a protein DNA Replication DNA making a copy of itself Steps: DNA Unzips Complementary nucleotides bond to the exposed nitrogen bases RNA: Ribonucleic Acid Shorter than DNA Only one strand No helix shape* Contains the base uracil (in place of thymine) Therefore uracil pairs with adenine RNA base pairing rule Cytosine - Guanine C-G Adenine - Uracil A-U Protein Synthesis 2 Steps: Transcription - copy DNA code Translation - DNA code used to make a protein Transcription : Copying the DNA Code Steps: 1. DNA unzips 2. mRNA nucleotides pair with complementary DNA nucleotides 3. mRNA leaves nucleus & travels to a ribosome Translation - - build a protein according to mRNA code tRNA (transfer RNA) brings amino acids to mRNA and puts them in proper order TAC CGG ACC ATT DNA triplet DNA triplet DNA triplet DNA triplet GCC UGG UAA mRNA codon mRNA codon mRNA codon CGG ACC AUU tRNA anticodon tRNA anticodon tRNA anticodon Alanine Tryptophan STOP amino acid amino acid AUG mRNA codon UAC tRNA anticodon Methionine amino acid TAC CGG ACC GTT ATT DNA triplet DNA triplet DNA triplet DNA triplet DNA triplet GCC UGG CAA UAA mRNA codon mRNA codon mRNA codon mRNA codon CGG ACC GUU AUU tRNA anticodon tRNA anticodon tRNA anticodon tRNA anticodon AUG mRNA codon UAC tRNA anticodon Methionine amino acid Alanine amino acid Tryptophan Glutamine amino acid amino acid STOP TAC CGG ACC GTT TAT ATT DNA triplet DNA triplet DNA triplet DNA triplet DNA triplet DNA triplet AUG GCC UGG CAA AUA UAA mRNA codon mRNA codon mRNA codon mRNA codon mRNA codon mRNA codon UAC CGG ACC GUU UAU AUU tRNA anticodon tRNA anticodon tRNA anticodon tRNA anticodon tRNA anticodon tRNA anticodon Methionine Alanine Isoleucine STOP amino acid amino acid Tryptophan Glutamine amino acid amino acid Amino acid Worksheet Pt B Top Diagram Terms: sugar, phosphate, base (use each twice) Pg 291, 294 Terms for middle diagram: Sugar (Pg 291) (Pg 300) #1-3, 5 replication double helix sugar Bases Number of Nucleotide Strands (1 or 2) (1 or 2) hydrogen base pairing rule phosphate transcription Worksheet Part D mRNA cytoplasm DNA bases (2) triplet ribosome protein peptide bond nucleus transcription codon base pairing rule amino acid translation anticodon tRNA