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1 Excellence and Leadership in Radiation Medicine Research, Education, and Clinical Practice DEPARTMENT OF RADIATION ONCOLOGY To Advance the Science and Practice of Radiation Medicine 2 Table of Contents Chair’s Report …………………………………… 5 Faculty List …………………………………… 9 Committees …………………………………… 12 Clinical Programs …………………………………… 15 Education Report …………………………………… 18 Medical Radiation Sciences Program ………………………….. 29 Equity Report …………………………………….31 Research Report …………………………………… 32 Research Grants ……………..…………………...… 36 Publications …………………………………… 57 Peer-reviewed …………………………………… 57 Non Peer-Reviewed …………………………………. 89 Book Chapters …………………………………… 91 Abstracts …………………………………… 95 Presentations …………………………………… 131 Awards …………………………………… 161 Research Day …………………………………….164 3 Department of Radiation Oncology Executive 2007/08 Chair Mary Gospodarowicz Vice-Chair Academic Affairs Pam Catton Vice-Chair Clinical Affairs Shun Wong Vice-Chair Academic Programs David Jaffray Directors Director Research Anthony Fyles Director Postgraduate Education Barbara-Ann Millar Director Equity Officer Fei-Fei Liu Director Undergraduate May Tsao 4 Director Fellowship Program Charles Catton Chair Letter It gives me great pleasure to present to you the University of Toronto, Department of Radiation Oncology (UT DRO) Annual Report for the academic year of 2007–2008. The Department continues to strive for excellence and leadership in radiation medicine research, education, and clinical practice. We continue to provide expert clinical care to cancer patients from Toronto, other regions of Ontario, and from across Canada at the Odette Cancer Centre (OCC) and Princess Margaret Hospital (PMH). Both institutions have expanded provincial and international partnerships in clinical care research and education. It is with pride that we announce our new Master of Health Science in Medical Radiation Sciences (MHScMRS) in partnership with the Institute of Medical Sciences at the University of Toronto, which will open in January 2009. With the addition of the MHScMRS Program and our new postgraduate program in clinical physics, we now offer a full slate of professional and research training programs. We are also very proud of our large international Clinical Fellowship Program that continues to attract fellows from all over the world. Over the past couple of years, our Medical Radiation Sciences (MRS) Program underwent a major curriculum redesign, which was implemented in September 2007. The redesign included several new interprofessional courses that focused on communication professionalized collaborative patient care and leadership in health care research. UT DRO is leading the joint Ontario Ministry of Health and Cancer Care Ontario Advanced Practice in Radiation Therapy Project. The Department continues to thrive under the leadership of its three ViceChairs: Professor Pamela Catton, Professor David Jaffray, and Professor Shun Wong. They share their thoughts later in this report. Our management and infrastructure continues to expand. This spring, we welcomed our new Administrative Manager, Effie Slapnicar MBA, who joined us from the Canadian Arthritis Network. Effie’s energies will focus on facilitating our departmental programs and innovation in practice. I hope that you will find both our regular report and the new shortened version informative. Mary Gospodarowicz MD FRCPC FRCR(Hon) Professor and Chair 5 Vice-Chair Reports Academic Affairs Pamela Catton As Vice-Chair for Academic Affairs, Pam Catton is responsible for the oversight of all education and financial activities in the Department. She works to build strong educational programs that serve the professional and research training needs of all radiation professional disciplines in an environment of fiscal responsibility. The reporting period of July 1, 2007 to June 30, 2008 saw a number of important Departmental initiatives come to fruition. Peter O’Brien, the Program Director of the Medical Physics Residency Program and his team were able to fulfill the highest requirements for accreditation by the Commission on Accreditation of Medical Physics Education Programs and were awarded a six-year accreditation. This is a remarkable vote of confidence in this new program’s ability to deliver quality physics education. Nicole Harnett, Graduate Program Director, and her team received an outstanding external review for the proposal to start a two-year professional masters program in Radiation Therapy. This MHSc Medical Radiation Sciences is unique to North America and will open in January 2009. Given the significant depth and breadth of our education programs, two new leadership positions in Physics and Radiation Biology Education were established to help integrate, coordinate and enhance the teaching of these basic sciences across all programs. Jean-Pierre Bissonette for physics and Bradly Wouters for biology, have assumed these portfolios. It is a stimulating and exciting time as the education programs continue to develop, mature and evolve, informed by the richness of our academic interprofessional environment. 6 Vice-Chair – Clinical Affairs Shun Wong As Vice-Chair for Clinical Affairs, Shun Wong is responsible for policy and program issues related to relations with clinical sites and clinical faculty. In this portfolio, he oversees the appointment, 3-year review and promotions of members of the Department, and ensures that the recruitment and medical manpower plan at the clinical sites is aligned with the academic plan of the University Department. The past 12 months have witnessed continuing growth of clinical, research and educational activities at Princess Margaret Hospital-University Health Network and Odette Cancer Centre-Sunnybrook Health Sciences Centre. Both centres continued with upgrading of planning and treatment machines as well as state-of-the-art information systems. The program at both sites also benefited from strong philanthropic support by the respective hospital foundations. The Department continued to foster its regional leadership in cancer research and care. Padraig Warde on part time secondment was appointed as Acting Head of Radiation Program at the Southlake Hospital, and Juhu Kamra was appointed as Head of Radiation Oncology of the Royal Victoria Hospital. John Rowlands was appointed the inaugural Director of the Molecular Medicine Research Centre, a clinical research partnership with the Thunder Bay Regional Health Sciences Centre and Lakehead University. In addition, the Department continued to provide education and clinical support to many academic and community hospitals both within and outside the central LHIN. Congratulations are in order to Jim Brierley, Jean-Philippe Pignol and Richard Tsang who were promoted to the rank of Professor, and Joyce Nyhof-Young to the rank of Associate Professor. The following new appointments were made to the department: Arjun Sahgal, Assistant Professor; Shao Hui (Sophie) Huang, Lecturer; Andrew Hope, Assistant Professor; Bradly Wouters, Professor; and Marianne Korizinsky, Assistant Professor. 7 Academic Programs David Jaffray As Vice-Chair for Academic Programs, David Jaffray is responsible for the oversight of all research activities in the Department and works to build academic pursuits that bridge the faculty, facilities, and programs found within the Department. The reporting period of July 1, 2007 to June 30, 2008 was particularly rich with successes and endeavors. The following items of note demonstrate the scope and depth of this dynamic Department. October saw the long-awaited grand opening of the Spatio-Temporal Targeting and Amplification of Radiation Response (STTARR) Innovation Centre in the MaRS tower – a $22M facility with investments from industry, government, and philanthropy all working together to improve our understanding and application of the radiotherapeutic effect. This infrastructure provides an ideal environment for collaboration within the Department and with other fields of medical research. The building of research faculty in the Department and the engagement of other institutions in this activity is a sign of things to come. Bradly Wouters, PhD was recruited to the Department with the support of the Ontario Institute of Cancer Research (OICR) to advance our understanding of radiation response and the microenvironment. David Hodgson, MD received a Level 1 Cancer Care Ontario Research Chair in the first CCO Research Chair competition, for studies of patient and provider characteristics associated with the provision of optimal cancer care, and on identification and quantification of long-term outcomes of cancer treatment, particularly the evaluation of late toxicity among survivors. Kristy Brock, PhD was awarded a Level 2 Cancer Care Ontario Research Chair based on her international reputation for pioneering work in deformable image registration, multi-modality imaging for radiation therapy, quantification and evaluation of organ motion and deformation, and assessment of treatment response. The receipt of dedicated faculty awards creates a platform for further growth in these areas. This is demonstrated in the growth of research grants held by the Department – a number that is now approaching $20M per annum (2006-2007). Toronto was host to the combined Canadian Association of Radiation Oncologists (CARO) and Canadian Organization of Medical Physicists (COMP) annual meetings. Many of our faculty participated in administrative, educational, and scientific activities for this meeting. The meeting was a great success with joint sessions that celebrated the collaborations that make Radiation Oncology a dynamic and progressive field. The Department is clearly the place to be. The resources, the strength of our partners, and the culture of collaboration (internal and external) are world-class. 8 Faculty Radiation Oncology Professor Pamela Catton Juanita Crook Bernard Cummings Shun Wong Mary Gospodarowicz Anthony Fyles Gillian Thomas Fei-Fei Liu Brian O’Sullivan Padraig Warde Laura Dawson David Hodgson Robert Bristow Robert MacKenzie Michael Milosevic Lawrence Paszat David Payne Eileen Rakovitch Normand Laperriere Rebecca Wong Jolie Ringash Richard Tsang Robert Dinniwell Mary Doherty John Kim Anne Koch Wilfred Levin Andrew Loblaw Lee Manchul Thomas McGowan Michael McLean Cynthia Ménard Barbara-Ann Millar Gerard Morton Ian Poon Arjun Sahgal Alexander Sun Ewa Szumacher May Tsao Yee Ung John Waldron Woodrow Wells Associate Professor Ida Ackerman Andrea Bezjak Jim Brierley Charles Catton Edward Chow Cyril Danjoux Jean Philippe Pignol Assistant Professor Judith Balogh Lisa Barbera Elizabeth Barnes Andrew Bayley Anthony Brade Patrick Cheung John Cho Peter Chung Gregory Czarnota Phillip Davey Lecturer Jacqueline Spayne Radiation Physics Professor David Jaffray John Rowlands Assistant Professor Hamideh Alasti Jean-Pierre Bissonnette Stephen Breen Kristy Brock Allison Brown Young-Bin Cho James Chow Tim Craig Mostafa Heydarian Mohammad Islam Harald Keller Katherine Mah Howard Michaels Douglas Moseley 9 Peter O’Brien Geordi Pang Thomas Purdie Michael Sharpe Douglass Vines Collins Yeboah Ivan Yeung Lecturer Parminder Basran Alexander Lightstone David Beachey Robert Heaton Radiation Therapy Assistant Professor Carol Gillies Lecturer Amanda Bolderston Caroline Davey Lisa DiProspero Instructor Ruth Barker Renate Bradley Angela Cashell Martin Chai Lori Holden Tara Rosewall Cynthia Eccles Nicole Harnett Valerie Kelly Karen Moline Cathryne Palmer Patricia Charman Fiona Cherryman Marta Evans Wendy Flanagan Jane Higgins Kari Osmar Marc Potvin Aisha Sheikh Education Assistant Professor Joyce Nyhof-Young David Wiljer Cross-appointments Professor Associate Professor Richard Hill Michael Rauth Alex Vitkin Assistant Professor Alan Rawlinson Jeff Siewerdsen Milton Woo New Appointments 2007-2008 Andrew Hope Sophie Huang Marianne Koritzinsky Emily Sinclair 10 Bradly Wouters Departures 2007-2008 Juhu Kamra Robert Luke Neil McParland Promotions- Effective July 2008 Professor James Brierley Jean Philippe Pignol Richard Tsang Associate Professor Joyce Nyhof-Young Administrative Staff Administrative Manager Department Secretary Administrative Coordinators: Resident Training Program Physics Residency in Radiation Oncology Fellows Medical Radiation Sciences Program: Associate Registrar Student Services Officer Administrative Assistant 11 Mary Cunningham Rosa Da Silva Kim O’Hearn Wanita Lambert Elena Gessas Jeremy Kwan Humberto Rocha Tanya Webb Department of Radiation Oncology Committees Executive Committee Mary Gospodarowicz – Chair Mary Cunningham Pamela Catton Peter Chung Anthony Fyles Nicole Harnett David Jaffray Barbara -Ann Millar Fei-Fei Liu Peter O’Brien Cathryne Palmer John Rowlands Jacqueline Spayne Padraig Warde Shun Wong Finance Committee Pamela Catton – Chair Mary Cunningham Bernard Cummings Mary Gospodarowicz David Jaffray Shun Wong Appointments Committee Shun Wong – Chair Pamela Catton Anthony Fyles Carol Gillies Mary Gospodarowicz David Jaffray Fei-Fei Liu John Rowlands External Relations Committee Anthony Brade – Chair Kristy Brock Mary Cunningham Gregory Czarnota Rosa DaSilva Robert Dinniwell Academic Promotions Committee Shun Wong – Chair Pamela Catton Anthony Fyles Mary Gospodarowicz Research Advisory Committee Anthony Fyles – Chair Charles Catton David Jaffray Fei-Fei Liu 12 Zahra Kassam Kim O’Hearn Sarah Rauth Tanya Webb David Wiljer David Jaffray Fei-Fei Liu John Rowlands Gillian Thomas Michael Milosevic Jean-Philippe Pignol John Rowlands Teaching Effectiveness Committee Pam Catton – Chair Ida Ackerman Jean-Pierre Bissonnette Cathryne Palmer Education Committees Undergraduate Medical Education Juhu Kamra – Chair Lee Manchul Joyce Nyhof-Young Ewa Szumacher May Tsao Woodrow Wells Postgraduate Education Pam Catton / Barbera-Ann Millar – Chair Ida Ackerman Robert Bristow Charles Cho William Cho William Chu Meredith Giuliani Adrian Ishkanian Stanley Liu Fellowship Charles Catton – Chair Anthony Fyles Mary Gospodarowicz Michael Milosevic Sten Myrenhaug Peter O’Brien Kim O’Hearn Jean-Philippe Pignol Hany Soliman Eileen Rakovitch Woodrow Wells Rebecca Wong Gerard Morton Woodrow Wells Shun Wong 13 Department of Radiation Oncology Representation On University of Toronto Committees Catton, P Faculty of Medicine Education Committee, Member IMS Admissions Committee, Member Gospodarowicz, M Clinical Relations Committee, Faculty of Medicine, Member Medical Radiation Science Board of Examiners, Member Faculty Council, Faculty of Medicine, Member Harnett, N Faculty Council, Faculty of Medicine, Member Manchul, L Continuing Education Council, Faculty of Medicine, Chair Nyhof-Young, J Dean’s Advisory Committee on Gender Issues, Faculty of Medicine, Member Ringash, J Academic Board of the Governing Council, Member Faculty Council, Faculty of Medicine, Member Faculty of Medicine Research Grants Committee, Member 14 Clinical Programs Princess Margaret Hospital Mary Gospodarowicz The Princess Margaret Hospital Radiation Medicine Program (RMP) is one of the largest in the world. With modern facilities equipped with 16 linear accelerators, all IMRT and IGRT enabled, Leksell Gamma Knife 4C and Perfexxion, HDR and PDR brachytherapy programs, it is capable to handle any radiation therapy situations. The clinical expertise spans all cancer sites with large breast, lung, genitourinary, upper and lower gastrointestinal, gynecologic, head and neck, central nervous system, ocular, lymphoma, sarcoma, skin, endocrine and pediatric radiation oncology groups. In 2007 – 2008, PMH RMP continued to expand its clinical and academic programs. RMP faculty provided consultations in many collaborating institutions including St Michael’s and St. Joseph’s Hospitals in Toronto and the Southlake Cancer Centre in Newmarket. The research programs in CT PET simulation, MR simulation and Image Guided radiation therapy continued to make excellent progress with a very successful symposium “Magnetic Resonance Comes of Age” at the combined 2007 Annual Scientific Meeting of the Canadian Association of Radiation Oncology and the Canadian Organization of Medical Physicists led by Cynthia Menard. RMP PMH leadership extends well beyond radiation oncology and Toronto. Brian O’Sullivan developed the strategic plan for Princess Margaret Hospital Cancer Program. The partnership with the Aviano Cancer Centre in Italy saw faculty from Italy visit PMH. Mary Gospodarowicz joined the Aviano’s International Scientific Advisory Board led by Prof Dalla Favera from the Columbia University in New York City. Padraig Warde was appointed as Acting Head of the Radiation Medicine Program in the Southlake Cancer Centre. He has also been appointed as Chair of the Radiation Oncology Provincial Advisory Committee. Michael Milosevic became the President of the Canadian Association of Radiation Oncology for the 2007-2009 term of office. Bernard Cummings, Mary Gospodarowicz, and Brian O’Sullivan were named Fellows of the American Society of Therapeutic Radiology and Oncology (FASTRO). FASTRO designation is based upon meritorious service to ASTRO and to the field of radiation oncology including leadership/service, research, patient care and education. The research programs continued to expand. Last year witnessed the formal opening of the STTARR Innovation Centre in the MaRS (Medical and Related Sciences) complex in the University Health Network. Funded by the 15 Canadian Foundation for Innovation STTARR is the heart of the translational biology and technology research programs of RMP. Led by David Jaffray, Robert Bristow and Michael Milosevic, this collaborative program extends its reach well beyond radiation oncology engaging surgery, pathology, imaging, and others in collaborative research. David Hodgson was awarded a level 1 Cancer Care Ontario Research Chair in Patterns of Care, and Kristy Brock, a level 2 Cancer Care Ontario Research Chair in Cancer Imaging, in the first CCO Research Chairs competition. RMP supported unprecedented number of undergraduate MRS students (23), clinical fellows (20), and hosted 5 international IGRT courses with participants from Europe, Australia, Asia, and North America. RMP PMH was awarded a grant from Cancer Care Ontario to organize a comprehensive IMRT Course for the province to run four times over the next two years. Michael Sharpe PhD, the Course Director will lead this initiative. We welcomed many new staff to the program including Catherine Coolens PhD who joined us from the Institute of Cancer research and Royal Marsden NHS Trust and Andrew Hope MD who joined us from Washington University in St Louis. Bradly Wouters PhD joined the Ontario Cancer Institute and PMH RMP from the Department of Radiation Oncology (Maastro Lab), GROW Research Institute and Maastricht University in Netherlands. With the best staff, clinical infrastructure, education and research programs, while the Princess Margaret Hospital Cancer Program aspires to be one of the five top comprehensive cancer programs, the Radiation Medicine Program aspires to be the best. Toronto-Sunnybrook Regional Cancer Centre Shun Wong The past twelve months have witnessed continuing growth of the clinical, research and educational activities of the Radiation Treatment Program at Sunnybrook Health Sciences Centre. Just over 6100 new radiation oncology patients were seen in fiscal year 07-08, an increase of 6.5% from 06-07, and about 100,000 fractions of radiation treatment were delivered. Upgrades to the existing clinical infrastructure continued with the installation of two new linacs with image-guided radiation treatments (IGRT) capability. A CT simulator replaced the conventional simulator. Many specialized programs including Tomotherapy, IGRT using cone-beam and brachytherapy continued to expand. Stereotactic body radiation therapy was implemented, and other upgrades in technology continued. The Radiation Treatment Program benefited form a large philanthropic support from Mr. Edmond 16 Odette to enhance its academic objectives, specifically in imaging research and image-guided radiation treatments. Juhu Kamra was appointed as Head of Radiation Oncology of Royal Victoria Hospital, but will remain as consultant staff at Sunnybrook. Four radiation oncologists were successfully recruited to start over the next two academic years. The Program continued to foster its regional leadership role in cancer care. A temporary radiation treatment facility, a partnership between the Royal Victoria Hospital (RVH) and the Radiation Treatment Program at Sunnybrook began operation in April 2008.Radiation Oncologists continued to participate in peripheral clinics at RVH, Toronto East General Hospital and North York General Hospital. The Program continued to provide multidisciplinary cancer conference support to a number of community hospitals within and outside of the Toronto Central LIHN. Faculty members were successful in securing a number of multi-year external peer-reviewed grants. These research grants including a number of large awards (Poon, OICR; Czarnota, US Army; Pignol, CBCF) are detailed elsewhere in the annual report. The Rapid Response Radiation Program (Chow) was awarded the Co-op student of the year Employer Award by Education at Work Ontario for education leadership. 17 Education Report In 2007-2008, the UT DRO continued its strong commitment to high quality health professional education and research training and a number of important Departmental initiatives came to fruition. Peter O’Brien, the Program Director of the Medical Physics Residency Program and his team were able to fulfill the highest requirements for accreditation by the Commission on Accreditation of Medical Physics Education Programs and were awarded a five-year accreditation. This is a remarkable vote of confidence in this new program’s ability to deliver quality physics education. Nicole Harnett, Graduate Program Director, and her team, received an outstanding external review for their proposal to start a two-year professional masters program in Radiation Therapy. This MHSc Medical Radiation Sciences is unique to North America and will open in January 2009. A number of leadership positions changed hands in the 2007-2008 academic year. Barbara-Ann Millar became the Program Director of the Radiation Oncology Residency Program, assisted by Woodrow Wells, Associate Program Director. Pamela Catton served as Acting Program Director during Barbara-Ann Millar’s maternity leave. Juhu Kamra stepped down from the Undergraduate Medical Education portfolio in April, to be succeeded by May Tsao as Director, and Joyce Nyhof-Young as Associate Director. Given the significant depth and breadth of our education programs, two new leadership positions in Physics and Radiation Biology Education were established to help integrate, coordinate and enhance the teaching of these basic sciences across all programs. Jean-Pierre Bissonette for Physics and Bradly Wouters for biology assumed these portfolios. Graduate Education Introduction In 2007-2008, efforts to enhance our involvement in graduate education at the University of Toronto continued. Master’s of Health Science, Medical Radiation Sciences In January 2009, the Institute of Medical Science (in collaboration with UT DRO) will launch the very first radiation therapy focused master’s program in North America. After several years of development and collaboration, the program received final approval from both the University of Toronto and the Ontario government in Spring 2008. 18 For many years, radiation therapists interested in pursuing discipline specific graduate education were forced to go abroad and study primarily through distance learning formats completing module or research-based programs. This professional master’s is unique in that it prepares radiation therapists, interested in continuing their clinical work, for an academic and advanced practice. The eight credits, full time program provides an excellent complement to the research master’s program already offered through IMS to qualified radiation therapists. Curriculum development is currently underway for the nine new radiation medicine-focused courses and will draw heavily on our local expert faculty at Odette Cancer Centre and Princess Margaret Hospital. The program also requires students to complete the existing IMS courses in radiation oncology including Translation Biology applied to Radiation Science, Frontiers in Radiation Medicine Research, and Advanced Radiotherapy and Medical Physics. This will allow students to study in a more multidisciplinary environment and learn from their fellow students. With initial registration set at five students per year, it is hoped that over the following 5 years, the program will expand to accept at least ten radiation therapists annually. It is hoped that this program will become the gold standard for advanced academic preparation for expert radiation therapists around the country and beyond. In 2007-2008 the following UT DRO graduate students were enrolled in the MSc/PhD stream in the Institute for Medical Sciences: Name Degree Program Supervisor Chan, Phillip Dinniwell, Robert Bachtiary, Barbara Keller. Brian Letourneau, Daniel Franks, Kevin Koh, Eng-Siew Case, Robert Christiansen, Eva Lim, Karen Mehdizadeh, Hany MSc MSc MSc PhD PhD MSc MSc MSc MSc MSc MSc A. Fyles M. Milosevic A. Fyles J.P. Pignol D. Jaffray D. Jaffray P. Catton L. Dawson R. Bristow M. Milosevic J. Siewerdsen 19 EIRR 21 Research Training Program The Excellence in Radiation Research for the 21st Century (EIRR21) Training Program entered its fifth year (Funded by the Canadian Institute of Health Research. It has graduated six trainees, four of whom hold academic research positions either at the Princess Margaret Hospital or Europe. Currently, there are 30 active trainees in EIRR21, including four MDs, many hail from other countries such as Australia, India, Germany, and the United Kingdom. The research domains cross several disciplines, ranging from basic genetic and molecular studies on radiation response, molecular imaging, bio-informatics, novel therapeutic approaches, technical improvements in radiation delivery, and biomarker evaluations for radiation response and toxicity in cancer patients. Hence, the trainees are nurtured in an environment, which facilitates cross-pollination of scientific ideas and approaches. The EIRR21 trainees continue to be highly productive, with a total of 62 peer-reviewed publications, one research grant, and four patent-filings. There have been several significant achievements of many EIRR21 trainees, including receipt of external competitive training awards such as NCIC, NSERC, and CIHR. Nadine Kolas (supervisor Dan Durocher) published a paper in Science (Kolas et al; Science 318:1637, 2007) on the novel role of RNF8 ubiquitin ligase in mediating DNA damage response. Naomi Matsuura (supervisor John Rowlands) was awarded the John Charles Polanyi Prize from the Ontario Government, in recognition of young talented researchers in the province. Hence, this research-training program fulfils the CIHR mandate to build capacity, innovate, conduct trans-disciplinary science, and be internationally competitive. The trainees enrolled in the Program in 2007-2008 include: Trainee Status Supervisor(s) Mocanu, Joe PhD F.F. Liu Bailey, Kristy MSc K. Vallis/ R. Reilly Boutros, Paul PhD I. Jurisica/L. Penn Costantini, Danny PhD R. Reilly/K. Vallis Cai, Zhongli PDF K. Vallis Kolas, Nadine PDF D. Durocher Macrae, Chloe MSc A. Koch Matsuura, Naomi PDF J. Rowlands Moniz, Larissa PhD V. Stambolic Vlad, Roxana PhD G. Czarnota 20 Zhang, Wei PhD D. Durocher Zheng, Jinzi MSc D. Jaffray Jacks, Kellie PhD A. Koch Kumareswaran, Ramya MSc R. Bristow Lau, Priscilla PhD P. Cheung Clending, James PhD L. Penn Christensen, Eva MSc R. Bristow Franks, Kevin MD A. Bezjak/D. Jaffray McLarty, Kristen PhD R. Reilly Li, Michelle MSc B. Derry Para, Andrea MSc R.P. Hill Stroian, Gabriela PDF J. Seuntjens Medical Education Undergraduate Medical Education Program Director: May Tsao The Department of Radiation Oncology continued to provide teaching to pre-clerkship (years 1 and 2) and clerkship (years 3 and 4) medical students. Pre-clerkship teaching included tutoring students in the Determinants of Community Health (DOCH) I course and providing lectures for the Foundations of Medical Practice and Pathobiology of Disease courses. Furthermore, a few University of Toronto radiation oncologists participated in teaching the DOCH II course. Twenty-four elective students, seven ambulatory Community Experience (ACE) students and four Ivan Smith awardees rotated through the Department. Postgraduate Medical Education Radiation Oncology Residency Program Director: Barbara-Ann Millar The UT DRO had 26 residents participating in its five-year training program. PGY1’s spent most of their first year off service in a basic clinical year comprised of surgical, medical and gynecological oncology, radiology, emergency medicine, general internal medicine, pediatrics, urology, and an elective. During January and February the Academic Block was offered, consisting of eight weeks of classroom based interprofessional teaching. Modules in CanMEDS, the Fundamentals of Research, the Fundamentals of 21 Radiation Therapy and Introductory Oncology complemented the basic science teaching Radiation Oncology residents from Queen’s University Program and University of Toronto physics residents also attended. The PGY2’s spent six months off service in medicine and medical oncology and 6 months rotating in radiation oncology. PGY3 residents were based at the Odette Cancer Centre (OCC), under the supervision of Ida Ackerman, Site Residency Coordinator. Basic physics knowledge and its application in clinic are emphasized. PGY4 and PGY5 residents continued to improve sitespecific knowledge and radiation practice competencies at both the Odette Cancer Centre and the Princess Margaret Hospital. The Annual Research Day was held at the Faculty Club this year on May 10, 2008. Given the large number of radiation oncology residents, fellows, physics residents and graduate students, we accepted 49 abstracts by peer review. Eleven residents presented research projects, nine as podium presentations. Adrian Ishkanian won the W.J. Simpson Award for Academic Excellence in Research by a Resident (Supervisor: Robert Bristow) for his work “High-resolution Array CGH Identifies Novel Regions of Genomic Alteration in Intermediate-risk Prostate Cancer”. A New Award was introduced this year for overall excellence and this award went to Adrian Ishkanian, PGY2, Radiation Oncology Resident and clinician-scientist at the University of Toronto, He was also awarded a 2008 Novartis Oncology Young Investigator Award for this year's ASCO meeting in Chicago June 2008. At CARO in 2007, nine residents had their abstracts accepted for the Resident Competition. All PGY5 residents successfully passed the RCPSC national certification examination in June, 2008. Residents 2007-2008 PGY1 Eman AlDuhaiby Amanda Caissie Meredith Giuliani Eric Leung Eve-Lyne Marchand Fazilat Mohammed PGY2 Adrian Ishkanian Kathy Han Elisa Chan Ameen Al-Omair 22 PGY3 Matthew Follwell Sten Myrehaug Hany Soliman Fred Yoon PGY4 Iwa Kong Louis Fenkell Behzad Banihashemi Stanley Liu Sarah Rauth PGY5 William Chu Charles Cho Christiaan Stevens Alina Sturdza Moji Taremi Yongjin Wang Jason Wong Residency Program in Radiation Oncology Physics Program Director: Peter O’Brien Site Coordinators: Jean-Pierre Bissonnette (PMH); Milton Woo (OCC) The Residency Program in Radiation Oncology Physics started in July 2007 by combining existing long-standing medical physics residency programs at the Princess Margaret Hospital and the Odette Cancer Centre. The goal of the new joint program is to produce highly competent medical physicists who combine a comprehensive understanding of clinical radiation physics and specific knowledge of radiation therapy and radiation oncology principles and practice with enhanced leadership, research and teaching skills. The program accepts applications from qualified and highly motivated candidates with a post-graduate degree in medical physics or a related discipline. The minimum program length is 2 years and includes a mix of didactic instruction, clinical rotations and clinical projects. Each resident is assigned a mentor to act as a guide throughout the program. During the first year the residents have didactic training in Radiation Biology, Radiation Safety, Clinical Radiation Physics and Dosimetry and the Principles of Treatment Planning. There are rotations in Instrumentation, Treatment Planning and Quality Management. In the second year there are rotations in 23 Brachytherapy and Imaging Physics, Advanced Treatment Planning and a continuation of Quality Management. Residents interact with radiation oncologists and radiation therapists during the Applied Physics tutorials and the Interdisciplinary Rotation that follows specific patients from first clinic to treatment. Resident knowledge is evaluated at regular, topical resident question and answer sessions based upon the program syllabus. To complete the program the resident must successfully pass the Peer Review A oral examination, organized by a standing provincial committee of Cancer Care Ontario. Jean-Pierre Bissonnette is a member of the Peer Review A examination committee. Throughout the 2-year program the resident is expected to work one or more clinical physics projects under the supervision of a staff medical physicist. The results of this work were presented as posters during the UT DRO Research Day and also as posters and oral presentations at the meetings of the Canadian Organization of Medical Physicists, and the American Association of Physicists in Medicine. The winner of the J.R. Cunningham award for academic excellence in research by a medical physics resident was Aaron Vandermeer. In the summer of 2007 the program committee applied for accreditation from the Committee on Accreditation of Medical Physics Education Programs (CAMPEP). A self –study and site-evaluation by a CAMPEP team were completed in the fall of 2007 leading to a full 5-year accreditation. The first graduates on the new CAMPEP accredited program were Xia Wu in December 2007, Lee Chin and Aaron Vandermeer in June 2008. The other residents, with clinical site and expected completion dates are Dylan Hunt, Rick Holly (October, 2008), Alex Karotki (September, 2009), Shahin Fattahi (January, 2010), Andrea McNiven (September, 2009, Claire McCann (February, 2010) and Alexandra Rink (January, 2010). Radiation Oncology Fellowship Programmes Program Director: Charles Catton The UT DRO Fellowship program is one of the largest in the world. Fellows spend one or two years in a Research Fellowship or a Clinical Research Fellowship. This past year 22 Fellows were involved in the program at both sites, coming from Australia (5); Canada (4); India (4), Ireland (2), UK (7). Three Fellows won travel awards to present their work, and another won second prize for best presentation at an international meeting. Five Fellows received directly to themselves over $374,000 in peerreviewed funding. This program remains successful and internationally highly regarded based upon the Fellows’ presentation and publication 24 record, positive exit interviews, and most importantly, a steadily increasing annual application rate as a consequence of referrals and recommendations from previous Fellows. Quality measures Abstracts presented: 72 Manuscripts published: 9 Manuscripts in preparation: 9 Grants: PI (n=5) $374,400 Awards: 1 ASTRO Travel award 1 Swiss League Against Cancer Travel Award 1 ISMRM Travel Award Second prize, best presentation at 4th ISV International Conference on Cancer Therapeutics 2007-2008 Fellows Supervisors Gaurav Bahl Debashis Biswas Supriya Chopra Max Dahele David Fitzpatrick Jayant Goda Asim Kamran Zahra Kassam Justin Lee Mark Lee Gerald Lim Karen Lim Chen Liu Orla McArdle Nikhilesh Patil Paul Sanghera Colin Tang Shaun Tolan Danny Vesprini Jonathan Wan Deborah Williamson Karen Wong Normand Laperriere/David Hodgson Anthony Fyles Cynthia Menard Mary Gospodarowicz/Andrea Bezjak Rebecca Wong Richard Tsang/Peter Chung Gerard Morton Jolie Ringash Gregory Czarnota Laura Dawson Andrea Bezjak Michael Milosevic/Anthony Fyles John Kim/John Waldron David Hodgson/Pamela Catton Juanita Crook Philip Davey/May Tsao Andrew Loblaw Michael Milosevic CharlesCatton/PadraigWarde/Robert Bristow Anthony Brade Anthony Fyles/Robert Dinniwell Jolie Ringash/John Waldron Continuing Education The Departmental CE activities were led by individual course directors, with oversight provided by Pamela Catton. 25 CEI³ Core Curriculum The UT DRO CEI³ is made up of a curriculum comprised of a fixed core of annual elements including UT DRO Rounds, and the Kingbrige Conference, in addition to a variable program hosted by UT DRO faculty. CEI³ complements a comprehensive continuing professional development program that takes place at PMH and TSRCC. Each program element has a Course Director, an interprofessional program and planning committee, is based on educational needs, is eligible for CE credits, intends to achieve an international profile and innovative elements, and is evaluated by standard educational criteria. UT DRO Rounds Coordinator: Anthony Fyles These twice-yearly symposia profile the academic programs of the UT DRO, share information and ideas between the two campuses, foster new research collaborations, and stimulate inquiry. Second Cancers Following Radiation. Moderator: Anthony Fyles • David Hodgson - learning from the fat man: modeling second cancer risk for clinical use • Fei- Fei Liu - Thinking outside the box.... how does breast RT induce sAML? • Jean- Philippe Pignol - Second cancers following breast radiation physics and solutions • Robert Bristow - DNA repair as a chemoprevention target following radiotherapy?" Other Continuing Education Activities All Department of Radiation Oncology faculty continued their active involvement in continuing education endeavours in a variety of capacities: course directors and invited speakers at local University of Toronto, national and international conferences, and as visiting professors. A number of faculty were involved in innovative continuing education initiatives including workshops, web-based and CD-ROM formats. For example, Ida Ackerman has developed a distance web-based collaboration with physics to teach clinical applied physics to radiation oncology residents in Australia. Patient-Centered Radiotherapy at Kingbridge April 26 – 27, 2008: King City, Ontario Course Directors: Amanda Bolderston and Ruth Barker 26 The 5th Annual Conference entitled “Global Perspectives, Local Outcomes” was held at the Kingbridge Conference Centre. Over the two days approximately 110 attendees from radiation therapy, radiation oncology, physics and pharmacy enjoyed a blend of topics in plenary, workshop and poster sessions. The program included a keynote speaker on Saturday - Gail Tomblin Murphy, Nurse and Professor at Dalhousie University, School of Nursing and Community Health and Epidemiology, who discussed driving forces and environment realities and how these impact our community of healthcare providers. Sunday’s keynote speaker was Marilyn Hammick, Radiation Therapist and Visiting Professor at the University of Central England and Anglia Ruskin University, and Chair of the UK Centre for Advancement in Interprofessional Education. Marylin Hammick’s lecture was also attended by a number of her interprofessional colleagues from George Brown College. The keynote speakers were followed by plenary sessions with afternoon concurrent workshops and oral abstract presentations. Posters were displayed throughout the conference with a formal presentation at a wine and cheese event on Saturday evening. Snapshot of evaluations: • Evaluation of the overall impression of the conference o 78% of attendees who completed the evaluation rated the conference either “good” or “excellent”. • Do you think this event will change your practice? o 61% of attendees who completed the evaluation said “yes”. • Would you recommend this conference to others? o 91% of attendees who completed the evaluation said “yes”. Next year’s conference will be held at the Old Mill, Toronto on March 6th and 7th. The conference will also incorporate the Radiation Therapist Research Symposium for the first time. The merging of these two successful events will provide a wider variety of concurrent research presentations in one convenient venue whilst also increasing the potential number of attendees. 27 IGRT Education Course The Image Guided Radiation Therapy (IGRT) Education Course is a collaborative educational course operated jointly by the UT DRO and the Radiation Medicine Program at PMH. Since its inception, 420 registrants have attended the course including 221 RMP staff and UT DRO students, residents and fellows. It is offered five times a year. The course engages over 30 faculty members, the majority of whom are UT DRO appointed faculty, and invited guest faculty from the broader radiation therapy community. This year Lei Dong, from MD Anderson in Houston, participated as a guest faculty member. The course continues to attract international participants from Europe, Asia and Australia, and many points throughout the US. It continues to be seen as the gold standard for IGRT education in radiation medicine circles. IMRT Education Course Intensity-modulated radiation therapy (IMRT) has emerged as the contemporary standard of care for patients with many forms of cancer. Given UT DRO’s reputation as a leader in radiation medicine and the academic home of many IMRT experts, CCO has sponsored the development of an IMRT Education Course in partnership with PMH and UT DRO. This course will give radiation medicine practitioners from around Ontario an opportunity to enhance their knowledge and skills in this area. The first internal offering was delivered in June 2008 to 30 internal attendees. The course and the 14 faculty members received high praise from participants. The new two-day educational program will consist of both theoretical and practical sessions to assist registrants prepare for IMRT implementation in their own centres. The course will begin in the fall of 2008 and will be run four times over the next two years. UT DRO Faculty in Continuing Education Leadership Several faculty continued to play a leadership role in the area of education administration as chairs of local and national continuing education committees and international organizations. Lee Manchul served as Chair of the Continuing Medical Education section of the Group on Educational Affairs within the American Association of Medical Colleges, Chair of the Continuing Education Council Faculty of Medicine, University of Toronto and Chair of the Education Committee for the Canadian Association of Radiation Oncology. 28 Medical Radiation Sciences Program After receiving all levels of approval at the Michener Institute and University of Toronto, the Medical Radiation Sciences Program has been actively developing and redesigning the curriculum. The first intake of students into the new curriculum commenced in September 2007. The MRS curriculum has been redesigned to include several courses that are interprofessional in nature, so that MRS students can learn with, from and about other healthcare professional students. Students entering the MRS Program in September will undertake a number of interprofessional education courses; specifically courses that focus on communication, professionalism, collaborative patient care, leadership in healthcare and research. Several of the discipline specific courses have been revised with some courses incorporating new material based on current clinical practice. For example students in all three disciplines will have as a component of their core curriculum a full course entitled “Integrated CT Imaging Theory & Practice.” No other programs in Ontario are educating their students to this level of practice. In addition, a clinical simulation semester, both interprofessional and discipline specific, will be implemented in the summer of 2009. Currently course development and approvals are underway for the academic year 2008/2009. There is representation from the MRS Program on several working committees organized through the Office of Interprofessional Education. As directed by the Council of Health Sciences Deans (CHSD), UT health professional students will participate in a longitudinal curriculum to acquire core competencies needed to provide patient-centered care, focusing on an interprofessional collaborative team approach. Program Quality: National Certification Results Radiological Nuclear Radiation Technology Medicine Therapy 68.4 (64.0) 98.3 (98.8) 2003 82.4 (88.7) 2004 92.7 (92.5) 78.9 (93.8) 96.9 (97.0) 2005 100.0 (95.0) 89.3 (87.1) 87.5 (87.0) 2006 84.0 (88.1) 90.6 (89.5) 97.1 (90.4) 2007 96.0 (94.2) 83.9 (82.8) 98.2 (89.2) Percent of students successful on the first write of the exam. National averages in brackets. 29 Each year, the Ontario Association of Medical Radiation Technologists (a provincial member of the national professional association) awards the T.B. Hurst award to the graduate who achieves the highest score on the Canadian Association of Medical Radiation Technologists certification examination in each of the disciplines. In 2007, UT/TMI Medical Radiation Sciences students, won in the disciplines of: Radiation Therapy: Iris Wong Nuclear Medicine: Melissa Roza Student Statistics: Enrolment Radiological Technology Class 2010 39 Class 2009 38 Nuclear Medicine 34 36 Radiation Therapy 63 53 Graduation Numbers: (eligible to graduate November 2008) Graduation Radiological Nuclear Radiation Technology Medicine Therapy Class 2008 31 33 62 Total 136 127 Total 126 Student Academic Awards: Overall Highest Academic Standing: Gold, Silver and Bronze awards are given to the graduates attaining the highest overall gap at the November 2007 Convocation Ceremony Gold Medallist: Silver Medallist: Bronze Medallists: Pavlo Ohorodnyk - Radiological Technology Daphne Chan - Radiation Therapy Jin Huang - Nuclear Medicine Research Awards: University of Toronto/Michener Institute Award for Excellence in Research by a Final Year Medical Radiation Sciences Student. Winner: Jaclyn Gouin - Radiation Therapy Title: The impact of daily travel on fatigue scores in a prostate cancer population at the Windsor Regional Cancer Centre Co-Supervisors: Colvin Springer & Siobhan Ozard Honourable Mention: Title: Caitlin Gillan - Radiation Therapy Radiation therapy students' teaching 30 Supervisor: Honourable Mention: Title: Supervisor: expectations of therapists over the course of clinical practicums: a longitudinal study Cate Palmer Peter Geu Machar - Nuclear Medicine PET/CT and the Attenuation Correction of PET Studies R. Glenn Wells & Donald Kuhl Clinical Project Awards: In each discipline the students who have the highest combined marks for Clinical Project I & II are recognized for their achievements. Radiological Technology: Outstanding achievement in clinical project: Honourable mention: Honourable mention: Navindra Johnie Rachel Au Dong Xu Nuclear Medicine Outstanding achievement in clinical project: Honourable mention: Roxana Fung Avelene De Souza Radiation Therapy Outstanding achievement in clinical project: Honourable mention: Allison Michelle Mills Erin Elizabeth Dwyer Equity Report Program Director: Fei-Fei Liu A new appointment has been made in 2007, for an Equity Officer in the UT DRO. The responsibilities for this position include developing, implementing and evaluating programs to maintain an inclusive learning environment, and ensuring an atmosphere of sensitivity for cultural, ethnic, and diversity issues, along with gender equality. Given the extensive intersections of UT DRO faculty and trainees with many other host institutions including hospitals, research institutes, training programs, and other schools within the larger UT environment, the Equity Officer will minimize duplication of efforts and programs, and instead, will be playing a major role in facilitating resolution of potential conflicts, and access to relevant resources at the host institutions. 31 Research Report The UT DRO research program continues to grow and consolidate its profile as one of the pre-eminent multidisciplinary radiation medicine research programs in the world. The following report summarizes the areas of progress, new initiatives, and benchmarks of success in 2007-2008. Research in UT DRO is conducted in all domains of radiation medicine; including radiation physics, therapy and nursing. The scope includes clinical research, quality of life and health services and outcomes research, basic and translational studies related to radiation response, and advanced highprecision radiation and imaging. Research is performed in collaboration with the other clinical and basic science departments, extra-departmental units including hospital research institutes, both within and outside of the University of Toronto. The UT DRO Research Committee advises regarding research priorities in DRO, fosters collaboration between research units and hospitals, advises regarding resident and fellowship research training programs, identifies mechanisms for funding, and monitors departmental research output and benchmarks. Research Highlights 2007-2008 • David Hodgson was awarded a Level 1 Cancer Care Ontario Research Chair in the first CCO Research Chair competition, for studies of patient and provider characteristics associated with the provision of optimal cancer care, and on identification and quantification of longterm outcomes of cancer treatment, particularly the evaluation of late toxicity among survivors. • Kristy Brock was awarded a Level 2 Cancer Care Ontario Research Chair based on her international reputation for pioneering work in deformable image registration, multi-modality imaging for radiation therapy, quantification and evaluation of organ motion and deformation, and assessment of treatment response. • Barbara Bachtiary was awarded the Whiteside Award, given annually to a graduating IMS Master of Science student who has made outstanding scholarly contributions. Barbara Bachtiary is a 2003-2005 PMH and UT DRO Research Fellow, and a trainee with the EIRR21 (Excellence in Radiation Research for the 21st Century) Training Program, supervised by Anthony Fyles and Fei-Fei Liu. 32 • Ian Poon, C Caldwell, J Wright, P Jager, A Pugachev, K Higgins, and D Enepekides were awarded an OICR grant to study the role of PET in head and neck cancer. "The individualization of radical radiation treatment with the use of intra-treatment 2-(F-18) Flouro-2-Deoxy-DGlucose (FDG) positron emission tomography in advanced head and neck cancer", $689,814 over 3 years. • Fei-Fei Liu and co-applicants were successful in obtaining a CBCF grant “Developing and Validating a Predictive Micro-RNA Signature for Node-Negative Breast Cancer”, $393,105 over 3 years. • Drew Hope and co-investigators Richard Hill, David Jaffray, Geoffrey Liu, Igor Jurisica, Melania Pintile, Andrea Bezjak,, Rob Bristow, and Patricia Lindsay were awarded an NCIC grant titled “Improved radiation induced lung toxicity prediction with linked preclinical/clinical models and biomarkers”. $381,099 over 3 years. • Opening of the STTARR (Spatio-Temporal Targeting and Amplification of the Radiation Response) Innovation Centre at MaRS, with clinical and translational research protocols incorporating dynamic anatomic and functional imaging, biologic targeting and high-precision radiotherapy. • Jean-Philippe Pignol awarded a CBCF grant “A Phase II Study of adjuvant Permanent Breast Seed Implant (PBSI) for Ductal Carcinoma In Situ”, $448,340 over 3 years. • Doug Vines and co-authors Harry Keller, Jeremy Hoisak, and Stephen Breen won a 1st place award for best paper of 2007 in the Journal of Nuclear Medicine Technology for "Quantitative PET Comparing Gated with Nongated Acquisitions Using a NEMA Phantom with Respiratory-Simulated Motion." • An Innovation Award from Cancer Care Ontario (CCO) and the Canadian Cancer Society for the development of Web Publishing, a secure web-based software application that provides comprehensive centralized storage of patient-specific radiation treatment information. • CBCF award to Greg Czarnota, Shun Wong, Peter Burns, and Stuart Foster for “Ultrasound analyses of vascular effects of radiation” Canadian Breast Cancer Foundation (Ontario Chapter): $428,000, 20072010 33 • Mary Gospodarowicz, Bernard Cummings and Brian O'Sullivan were elected ASTRO Fellows for 2007. This prestigious award is based on merit judged by the candidate’s service in a leadership role, research, patient care and education leading to a significant contribution within the field of radiation oncology. • Research awards have continued to increase, to a total of 388 in 20042007 (from 318 in 2003-2006), with increased total annual research funding to $19.0M in 2006-2007 (an increase from $15.7M in 20052006). • An increased number of clinical trials from 377 in 2006-2007 to 398 in 2007-2008. • 26.5% of UT DRO peer-reviewed publications were highly-cited in 2004 - 2007, comparable to peers at UBC and U Texas/MD Anderson. Indicators of Success Yearly Research Funding UHN-U of T Administered Funding: 2004- 2007 $19.0M $20 $15.7M $13.7M $15 Grant Other $16.2 $10 $11.1 $14.2 $0.4 $2.3 $0.3 $1.2 $0.6 $2.2 2004-2005 2005-2006 2006-2007 Industry $5 $0 Metric By Funding Source: N ($) By Purpose: N ($) Grant/ Agency Industry Other 2 Number of awards 310 57 1 Award per funded PI 6.8 1.3 0.5 Funding amount $41,496,712 $5,771,667 $1,243,90 $ per funded PI $922,149 $128,259 9$27,642 34 Operating 167 3.7 Traineeship 157 3.4 Other 64 1.4 $41,450,465 $2,325,525 $4,736,297 $921,121 $51,678 $105,251 Total 388 8.6 $48,512,287 $1,078,05 0 0 Papers per PI per year Cites per Paper Proportion cited 711 7147 1.9 10.1 83.0% U of T All 722 7188 1.4 10.0 82.8% MD Anderson 554 5849 3.2 10.6 84.1% UBC 155 1414 0.8 9.1 81.3% 30% Highly cited Citations U of T Core (June 2008) Institution Papers Publications: 2004-2007 28.4% 26.5% 23.5% 20% 10% 19.7% In High-Im pact Journals 10.8% 6.7% 0% 8.4% 2.0% 2004 2005 2006 2007 35 Research Grants Barbera L. The quality of palliative and end of life care in cancer patients. Ontario Ministry of Health and Long Term Care Career Scientist Award. $301,875, 2004 - 2008. Barzda V, Rowlands JA. Nonlinear microscopy imaging for clinical diagnostics. Natural Science and Research Council, Strategic Project Grant. $384,713, 2008 - 2010. Barzda V, Peshko, I, Rowlands J. Cancer tissue diagnostics with non-linear multimodal microscopy. Ontario Centres of Excellence. $149,850. 2008 2009. Bayley A, Dinniwell RE, Rosewall T, Craig T: Automatic segmentation of target organs and normal tissues for prostate cancer. ACURA $32,500, 2008. Baxter N, Del Giudice L, Paszat L, Rabeneck L, Sutradhar R, Urbach D. The young adult survivors of cancer. Canadian Institutes of Health Research, $413,088, 2008 - 2011. Bradley G, Chugh D, Nyhof-Young J. Computer assisted learning for teaching oral pathology to dental students. Information Technology Course Development Fund. $29,534. 2006 - 2009. Bristow R, Hill R, Hedley D, Milosevic M, Fyles A, Yeung I. PMH Hypoxia Program project grant section 3: Hypoxia-mediated genetic instability: The role of DNA-dsb repair. National Cancer Institute of Canada-Terry Fox Program. $ 5,262,165. 2004 - 2009. Bristow R. Basic and translational studies of DNA damage and repair as relates to p53. National Cancer Institute of Canada-Canadian Cancer Society Salary Support Award. $80,000. 2004 - 2010. Bristow R. The p53 protein and DNA damage recognition. National Cancer Institute of Canada. $687,035. 2006 - 2011. Brock KK. Investigation of the inclusion of motion and deformation in dose calculations for external beam radiotherapy. University of Toronto Dean’s Fund. $9,801. 2005 - 2010. Brock KK, Dawson LA, Sharpe MB, Jaffray DA. Biomechanical modeling for high precision radiotherapy design, adaptation, and assessment. National Cancer Institute of Canada, Terry Fox Foundation. 36 Research Grants Cont’d… $281,904. 2006 - 2009. Brock KK Dawson LA, Sharpe MB, Jaffray DA, Craig T, Bezjak A. Dynamic multi-organ anatomical models for hypofractionated RT design and delivery. NIH/NCI US $814,351. 2008 - 2012 Bryant-Lukosium D, Bradish G, Bitoni L, Burns J, Dempsy C, Green E, Luxton S, McQuestion M, Wiljer D. Ontario Oncology APN interprofessional-mentorship program. Ministry of Health and Long-Term Care. $368,700, 2007. Catton C, Lukka H, Warde P, Levine M, Julian J, Chenug P, Gafni A, Bauman G, Parliament M, Wu J, Pickles T, Souhami L, Bahary JP. A randomized trial of a shorter fractionation schedule for localized carcinoma of the prostate. Canadian Institutes of Health Research. $2,295,833. 2005 2011. Catton P, Milosevic M, Devins G, Gallie B, Hodgson D, Howell D, Jadad A, Luke R, Rodin G, Wiljer D. The electronic living laboratory for interdisciplinary cancer survivorship research: bridging the gap for chronic cancer care (ELLICSR). Canadian Foundation for Innovation (CFI) and Ontario Innovation Trust (OIT). $1,199,700 2007 - 2009. Catton, P. Breast cancer survivorship program. Princess Margaret Hospital Foundation. $2,300,000. 2004-2007. Cheung P, Morton G, Loblaw DA, Choo R, Pang G, Sixel K, DeBoer G. Hypofractionation using a concomitant intensity modulated radiotherapy (IMRT) boost for localized high risk prostate cancer. Abbott-CARO UroOncologic Radiation Award. $22,559. 2006 - 2007. Cheung P, Loblaw DA, Morton G, Pang G, Zhang L: Matched cohort study of accelerated versus conventionally fractionated radiotherapy for localized high risk prostate cancer. Sanofi-Aventis, $619,000 2007 - 2009. Chopra S, Menard C, Milosevic M Haider M, Foltz W, Bristow R. Multiparametric MRI based evaluation of hypoxia in men with prostate cancer: Abbott-CARO Uro-Oncologic Radiation Award (ACURA). $43,400, 2008. Chow E, Panzarella T, Bezjak A, Wu J. Validation of a predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic. Canadian Institutes of Health Research. $180,192. 2004 2007. 37 Research Grants Cont’d… Chow E, Clemons M, Wu J, Bezjak A, Brundage M, Yee A, Bottomley A, Velikova G, Hoskin P. Development of a Canadian-led international bone metastases module to accompany European organization for research and treatment of cancer quality of life group core questionnaire (the EORTC QLQ-C30) for future clinical trials in patients with bone metastases. National Cancer Institute of Canada. $271,483. 2005 - 2008. Classen C, Ferguson S, Barbera L, Wiljer D, Chivers M, Urowitz S. Development of an internet-based support group for sexual problems due to gynecological cancer. National Cancer Institute of Canada, $35,000, 2008 – 2009. Czarnota GJ, Burns P, Hynynen K, Foster S, Kolios M. Novel methods for detecting breast cancer responses to ultrasound and microbubblepotentiated radiation treatments. Ontario Institute for Cancer Research Seed Funding. $60,000, 2007 – 2008. Czarnota GJ, Wong CS, Burns P. Ultrasound microbubble-potentiated enhancement of breast cancer responses to radiation. CDMRP Programme, US Army Breast Concept Grant. US$102,453, 2007 – 2008. Czarnota GJ, Wong CS, Burns P. Ultrasound microbubble-potentiated enhancement of prostate cancer responses to radiation CDMRP Programme, US Army Breast Concept Grant. US$377,883, 2008 – 2011. Czarnota GJ, Martel A, Stanisz G, Foster SF. VEVO-770 for highfrequency ultrasound imaging of tumour responses to cancer therapy. Ontario Institute for Cancer Research. $225,000, 2007. Czarnota GJ. Biophysical fundamentals of ultrasound backscatter. Natural Sciences and Engineering Council of Canada. $80,000, 2007 - 2012. Czarnota GJ, Burns PN, Hynynen K. New imaging method to detect ultrasound microbubble-potentiated enhancement of breast cancer responses to radiation. Ontario Institute for Cancer Research. $60,000, 2007 - 2008. Czarnota GJ, Wong CS, Burns PN, Foster SF. Ultrasound analyses of vascular effects of radiation. Canadian Breast Cancer Foundation (Ontario Chapter). $428,000, 2007 - 2010. Czarnota GJ, Brade A, Kolios M, Burns P, Foster S, Wong S. Assessing tumour responses to radiation: Role of the vasculature examined longitudinally using high-frequency ultrasound. Cancer Imaging Network of Ontario. $132,400, 2007 - 2009. 38 Research Grants Cont’d… Dawson LA, Jaffray DA. Stereotactic radiotherapy for primary and metastatic liver cancer. Elekta. $86,667, 2005 - 2007. Dawson LA, Dinniwell RE, Kim J, Ringash J, Craig T, Lockwood G. Image guided radiotherapy for primary and metastatic liver cancer. National Cancer Institute of Canada. $159,699, 2007 - 2010. Del Guidice L, Amin P, Syed S, Barbera L. Health care utilization and location of death of patients in Ontario with end-stage chronic nonmalignant conditions. Physician Services Incorporated Foundation. $8500, 2007. DiMarco C, Bray P, Lipa J, Bray P, Covvey D, Cowan D, DiCiccio V, Harris R, Wiljer D Natural language generation tools and methodologies for personalized e-health education systems: Bell University Labs. $50,000, 2008. Done S, Rakovitch E, Pintilie M, Knight J, Bull S. Developing a molecular classification of DCIS. Canadian Breast Cancer Research Alliance. $450,385, 2005 - 2007. Fenster A, Brock KK. Medical imaging instrumentation and software platform (IPP-MIIS). Ontario Institute for Cancer Research. $382,000, 2008 - 2012. Foster FS, Duckett AS. Imaging ocular anatomy and blood flow in a mouse model of glaucoma. National Glaucoma Research, American Health Assistance Foundation. $43,530, 2006 - 2007. Foster FS, Bronskill MJ, Burns PN, Henkelman RM, Martell A, Stanisz G, Plewes DB, Rowlands JA, Yaffe MJ. Medical imaging for cancer. National Cancer Institute of Canada – Terry Fox Foundation. $7,583,990. 2006 2011. Gallinger S, Bristow R, Cotterchio M, Manno M, Bishop T. The MYH gene and colorectal cancer risk. National Cancer Institute of Canada. $423,000. 2005 - 2008. Glover M, Koch A, Durocher D, Weinfeld M. The structural biology of DNA repair. National Cancer Institute of Canada. $142,850, 2004 - 2009. Gospodarowicz M, Catton P, Jaffray D, Harnett N, Wiljer D. Accelerated Education Program: Image guided radiation therapy. Elekta, RMP. $1,000,000, 2005 - 2010. 39 Research Grants Cont’d… Gospodarowicz M, Sobin L. Collaboration for global cancer and tobacco control – UICC. Centers for Disease Control and Prevention, Department of Health and Human Services. $304,615, 2005 - 2007. Grunfeld E, Paszat L, Levine M, Julian J, Maunsell E, Beaulieu M-D, Coyle D, Sussman J, del Guidice L, Wiernikowski J, Dent S, Grenier R, Robidoux A, Schreuer D, Sisler J. A randomized trial of a patient-centred strategy to facilitate transition of breast cancer survivors’ routine follow-up from specialist to primary care. Canadian Breast Cancer Research Alliance. $594,362, 2006 - 2010. Harnett N, Catton P. Clinical specialist radiation therapist demonstration project. Ministry of Health and Long Term Care Grant. $444,320, 2006 2007. Harnett N, Catton P. Clinical specialist radiation therapist demonstration project - Ministry of Health and Long Term Care Grant: $536,376, 2008 2009. Henkelman RM, Bronskill MJ, Burns PN, Foster FS, Plewes DB, Rowlands JA, Wright GA, Yaffe MJ. Medical imaging for cancer. National Cancer Institute of Canada. $1,425,844. 2006. Hill R, Fyles A, Milosevic M, Bristow R, Yeung I, Hedley D. Hypoxia in tumours: Clinical and experimental studies. National Cancer Institute of Canada. $5,935,083. 2004-2009. Hill R, Yeung I. Radiation-induced lung damage: Volume-effects & mitigation. Canadian Institutes of Health Research. $546,796. 2005 - 2009. Hill R, Bristow R, Boreham D, Bell R. Assessing skin exposure by measuring DNA damage in skin cells. National Institute of Allergy and Infectious Diseases. $171,781 USD. 2005 - 2010. Hodgson DC, Hoch J, Krahn M, Trudeau M, Krzyzanowska M, Henry D. Looking in Pandora’s Box: Predicting the uptake, cost and outcome of new cancer drugs in Ontario. Green Shield Canada Foundation. $134,183, 2008 2010. Hodgson D, Gospodarowicz M, Tsang R, Crump M, Meyer R, Sussman J, Yu E, Pintilie M, Siu S. A population-based study of Hodgkin’s Lymphoma: Opportunities to reduce cardiac late effects (ORaCLE). Canadian Institutes for Health. $236,438. 2005 - 2008. 40 Research Grants Cont’d… Hodgson DC, Grunfeld E, Elit L, Walker H, Sussman J, del Guidice L, Rakovitch E, Imrie K, Paszat L, Law C, Coburn N, Kwon J. Patterns of follow-up care among cancer survivors in Ontario. Cancer Care Ontario. $150,000. 2006 - 2007. Hope A, Hill R, Liu G, Jurisica I, Pintilie M, Bezjak A, Jaffray DA. Improved radiation induced lung toxicity prediction with linked preclinical/clinical models and biomarkers. National Cancer Institute of Canada $430,913. 2008 - 2010. Hoskins P, Grant R, Gray J, Levack P, Loblaw A, Makin W, Stephens R, Tyler H, Yarrow S. SCORAD feasibility study: A randomised feasibility study of single fraction radiotherapy compared to multi-fraction radiotherapy in patients with metastatic spinal cord compression. National Cancer Research Institute (UK). $77,000. 2007 - 2008. Husain A, Howell D, Sussman J, Barbera L, Bezjak A. Lung cancer patients’ experince with continuity of care and unmet needs. National Cancer Institute of Canada $35,000. 2008 Husain A, Howell D, Sussman J, Barbera L, Bezjak A. Lung cancer patients’ experince with continuity of care and unmet needs. National Cancer Institute of Canada - additional funding $7,715. 2008 Hynynen K, Bronskill M, Burns P, Chopra R, Czarnota GJ, Kolios M, Kucharczyk W, Rowlands J, Tavokkoli J, Whelan W: Focused ultrasound devices for noninvasive surgery and drug delivery. Ontario Research Fund, Research Excellence Fund. $8,422,827, 2007 - 2013. Irish JC, Siewerdsen J. Guided therapeutics (GTx): Translational research image-Guided OR (TRIGOR-A) Princess Margaret Hospital Foundation Grant-Engineering for Guided Therapeutics. $800,000. 2007 - 2008. Irish JC, Siewerdsen J. Guided therapeutics (GTx): Translational research image-Guided OR (TRIGOR-A) Princess Margaret Hospital Foundation Grant-Cone-Beam CT for Image-Guided Surgery. $400,000. 2007 - 2008. Irish JC, Siewerdsen J. Guided therapeutics (GTx): Translational research image-gGuided OR (TRIGOR-A) Princess Margaret Hospital Foundation Grant- Guided Therapeutics Operational Support. $600,000. 2007 - 2008. Islam M, Jaffray DA. A novel energy fluence monitor for real time verification of intensity modulated radiation therapy. Natural Sciences and Engineering Research Council. $125,000. 2005 - 2007. 41 Research Grants Cont’d… Jadad A, Gospodarowicz M, Heller L. eToolkits: Internet-based tools for the improvement of cancer pain management worldwide. Purdue Pharma, L.P. $2,532,330. 2005 - 2007. Jaffray DA, Brock KK. An MR based simulation process for advanced radiation therapy. Varian Oncology Systems. $1,400,000. 2003 - 2007. Jaffray DA, Bezjak A. Proposal for cone-beam CT guided radiation of solitary lung lesions. Elekta Oncology Systems. $87,000. 2005 - 2007. Jaffray DA. Spatio-temporal targeting and amplification of radiation response (STTARR) innovation centre: Imaging and animal support infrastructure enhancement. Canadian Foundation for Innovation/Ontario Innovation Trust. $11,679,531. 2004 - 2007. Jaffray DA, et al. Spatio-temporal targeting and amplification of radiation response (STTARR) Innovation Centre, Canadian Foundation for Innovation /Ontario Innovation Trust. $9,824,217. 2004 - 2007. Jaffray DA, Bristow R, Milosevic M. Spatio-temporal targeting and amplification of radiation response. Canadian Foundation for Innovation. $1,167,954. 2006 - 2009. Jaffray, DA. Image Analyses for Adaptive Prostate Radiotherapy. National Institute of Health /NIBIB. $197,106. USD, 2005 - 2009 Jaffray DA. Automated image registration for prostate radiotherapy. National Institutes of Health/NIBIB. $197,106 USD. 2005 - 2009. Jaffray DA. Multimodal contrast agents for therapy guidance. Canadian Institutes of Health Research. $364,719. 2005 - 2007. Jaffray DA. Technology Research Agreement (TRA) cone-beam CT Guided Radiation of Solitary Lung Lesions. Elekta $1,311,089, 2006 - 2008. Jaffray DA., Wong R. A prospective study to elevate cone-beam CT in the planning of patients for palliative radiotherapy. Elekta. $87,000. 2005 - 2007. Jaffray DA et al. Image Science for the new X ray: taking NEQ to task. NIH $ 295,000. 2006 - 2010. Jaffray DA. Treatment design and response monitoring in the head and neck using multimodal imaging. Philips Medical Systems. $1,142,480. 2006 2011. 42 Research Grants Cont’d… Jaffray DA. Development of auto-segmentation and online planning tools for palliative process. Philips Medical Systems. $174,128. 2006 - 2008. Jaffray DA. Quantification of deformation response. Philips Medical Systems. $174,128. 2006 - 2008. Jaffray DA. UHN RaySearch Corporation research collaboration. RaySearch Research. $555,165. 2006 - 2009. Jaffray DA. On-line perfusion measurement with contrast enhanced conebeam CT in radiation therapy. Canadian Institute of Health Research. $166,087. 2006 - 2009 Jaffray DA et al. The Cardiac Regeneration CARE Project: New therapies for CV. CIHR. $ 2,500,000. 2007 - 2011. Jaffray DA et al. The Regenerative Medicine Project (REMEDI). Canadian Institute of Health Research. $18,050,000. 2007 – 2011. Jaffray DA et al. Partial breast irradiation reduces the risk of cardiac injury in left-side patients compared to whole breast irradiation. Canadian Breast Cancer Research Alliance. $56,441. 2007 - 2009 Jaffray DA. Development of a framework to standardize acquisition and analysis of PET images for clinical trials. Ontario Institute for Cancer Research. $80,000. 2007. Jaffray DA. Lung cancer biomarker imaging. Ontario Institute for Cancer Research. $80,000. 2007. Jaffray DA. et al. Multi-Scalar, multi –modal imaging agent for detection and targeting. Ontario Institute for Cancer Research. $80,000, 2007. Jaffray DA, Keller H, Breen S. PET imaging for imaging pipeline platform. Ontario Institute of Cancer Research (OICR), 2007. Jiang R, Pignol JP. Specialized softward tool for breast cancer brachytherapy. Canadian Breast Cancer Foundation-Ontario Chapter. $123,000. 2006 - 2008 Karim K, Reznik A, Caldwell C, Pignol JP. Selective Photon Counting Semiconductor Pixel Array for Real- Time Imaging of 103- Palladium Seed in Permanent Breast Seed Implantation. NSERC $140.720. 2007 - 2009. 43 Research Grants Cont’d… Keller B, Pignol JP. A penumbra measurement optical bench. Head and Neck Foundation. $40,000. 2007. Knox J, Wong R, Darling G. Adjuvant sutent following chemoradiotherapy and surgery for esophageal cancer, phase II trial (ASSET). Bristol Meyers Squibb. $233,000. 2006. Koch A. Functional characterization of Xrcc4 phosphorylation in nonhomologus end joining. University of Toronto Dean’s Fund. $7,950. 2004 - 2009. Koch A. Functional characterization of a novel FHA-containing protein in the nonhomologous end joining pathway. Cancer Research Society (CRS). $55,000. 2007 - 2008. Kohandel M, Milosevic M, Sivaloganathan S, Oza A, Jaffray D, Hill R, Yeung I. Dynamics of multi-modal anti-angiogenic, anti-vascular and cytotoxic therapies: Potential for significant clinical impact. Canadian Institutes of Health Research/ Natural Sciences and Engineering Research Council. $425,973. 2007 - 2009. Kolios MC, Czarnota GJ, Kumaradas JC, Hunt JW. High-frequency ultrasound tissue characterization for cancer classification and treatment monitoring. Canadian Institutes of Health Research. $187,284. 2006 - 2009. Kolios MC, Czarnota GJ. Simultaneous acoustic and optical flourescence microscopy for monitoring single cell responses to chemotherapeutic exposure. Canadian Institutes of Health Research. $14,920. 2006 - 2007. Kolios MC, Whelan B, Czarnota GJ. Optoacoustic-imaging of cancer responses to therapy. Natural Sciences and Engineering Research Council. $336,000. 2006 - 2009. Krahn M, Naglie G, Shabbir S, Warde P, Tomlinson G, Laporte A, Trachtenberg J. Development and applications of the prostate cancer policy model. Canadian Institutes of Health Research. $45,000. 2006 - 2009. Krahn M, Alibhai S, Ritvo P, Laporte A, Tomlinson G, Naglie G, Trachtenberg J, Pham B, Warde P. Androgen deprivation therapy in prostate cancer patients: patterns of care, lifetime costs, and cost effectiveness of ADT treatment. CCS Research Grant. $326,774. 2007 2010. Levinson W, Laupacis A, Redelmeier D, Deber R, Hux J, Manuel D, Paszat L. An integrated training program in health and social science research to 44 Research Grants Cont’d… improve the health of marginalized populations. Canadian Institutes of Health Research. $1,350,000. 2003 - 2009. Lipscombe L, Paszat L. Diabetes risk following breast cancer. Canadian Diabetes Association. $82,206. 2007 - 2009 Liu G, Jurisica I, Narod S, Wong R. Molecular Epidemiology of esophageal cancer survival. Canadian Institutes of Health Research. $414,844. 2007 2012. Liu FF, Reilly R, Jurisica I. The next generation of gene transfer therapy for human nasopharyngeal cancer. Canadian Institutes of Health Research. $560,525. 2004 - 2008. Liu FF, Bezjak A, Bristow R, Catton P, Fyles A, Gospodarowicz M, Jaffray D, Jurisica I, Koch A, Paszat L, Roberts T, Vallis K, Wong CS. Excellence in radiation research for the 21st century (EIRR21). Canadian Institutes of Health Research. $1,800,000. 2003 - 2009. Liu F-F, Fyles A, McCready D, Miller N, Pintilie M, Hui A, Shi W. Developing a predictive micro-RNA profile for breast cancer. Weekend to End Breast Cancer IDEA Grant. $72,250. 2007. Liu F-F, Alajez N, Bastianutto C. Quest for the “stem cell” in nasopharyngeal carcinoma. Canadian Institutes of Health Research. $110,553. 2007 - 2008. Luke R, Wiljer D, Catton P et al. Stepping stones: A blended learning program for the breast cancer survivorship. Transition to employment project (STEP). Canadian Council on Learning (CCL) Work and Learning $70,000. 2006 - 2008. Luke R, Attack, L, Catton P, Friedman A, Neil S, Nyhof-Young J, O’Grady L, Secord S, Treviranus, J, Urowitz S, Wathen N, Wiljer D. Advanced patient education for cancer survivorship APEXS. Social Sciences and Humanities Research Council. $142,900. 2007 - 2009. Loblaw DA, Faria S, Lukka H, Pickles T, Klotz L, Cheung P, Pritchard K. Koru-Sengul T, Levine M. A randomized comparison of immediate versus deferred androgen deprivation therapy using goserelin for recurrent prostate cancer after radical radiotherapy (ELAAT). AstraZeneca. $5,650,000. 2006 - 2020. Loblaw DA, Cheung P, Morton G, Sahgal A, Tang C, Pang G, Tirona R, Basran P. Hypofractionated accelerated post-operative radiotherapy for 45 Research Grants Cont’d… prostate cancer. CARO-ACURA Award $20,775, 2008 – 2009. Loblaw DA, Dayes I. Educational grant for CME Event, Urology Conversations, Mississauga, AstraZeneca $15,000, 2007 Loblaw DA, Fleshner N: Educational grant for CME event, new insights into old controversies in prostate cancer, Toronto. AstraZeneca. $15,500, 2007 Maamoun J, Fitch M, Robson S, Barker R, Lange-Mechlen I. Sangha A, Turner A, Gillies C. Identifying, measuring and addressing radiation therapy patients supportive care needs at TSRCC, practice based research. Sunnybrook Health Sciences Centre. $13,500. 2007. Mabbott D, Laperriere N, Sharpe M, Bouffet E. Retrospective study of changes in white matter integrity and cognitive function following cranial radiation for pediatric brain tumors. C17 Research Network Grant $94,000 2007 - 2009. Mabbott D Laperriere N, Sharpe M, Bouffet E. Prospective changes in white matter integrity and cognitive function following cranial radiation for pediatric brain tumors. NCIC, $700,000 2007 - 2012. Mandelis, Vitkin A. Facility for advanced bio-acousto-photonics, infrastructure grant. Canadian Foundation for Innovation. $1,682,421, 2007. Martin J, Catton C. A randomized trial of a shorter radiation fractionation schedule for the treatment of localized prostate cancer (PROFIT: Prostate fractionated irradiation trial). (AUS) $100,000. 2007 Martel A, Stanisz G, Yaffe M, Czarnota G. Platform for histopathological correlation of ultrasound and MRI detected tumour data. Ontario Institute for Cancer Research. $85,000. 2007 - 2008 Matsuura M, Rowlands JA. Novel nanostructure assemblies. The Ontario Cancer Institute for Research, Imaging Platform Seed Fund. $66,350. 2007 MacKillop W, O’Brien P: Improving cancer outcomes by optimizing the accessibility and quality of radiotherapy in Canada. Canadian Institutes of Health Research. $1,492,329, 2006 - 2011. Ménard C, Brock K. Integration of diagnostic and interventional MRI for the study of persistent prostate cancer after external beam radiotherapy. Department of Defense Prostate Cancer Research Program. $294,600 USD, 2005 - 2008. 46 Research Grants Cont’d… Ménard C, Chung P, Catton C, Bayley A, Haider M, Craig T, Rosewall T. Advanced image guidance will improve toxicity outcomes for patients with prostate cancer: A prospective study. Abbott-CARO Uro-Oncologic Radiation Award. $19, 300. 2007. Ménard C. Exploring the role of 3T MRI in gamma knife radiosurgery: A pilot study. Ontario Cancer Research Network Junior Investigator Award Program. $40,000. 2006 - 2007. Ménard C. IG-IMRT after radical prostatectomy. Royal Victoria Hospital Foundation – Motorcycle Ride for Dad Grant Competition: $40,000D. 2007 - 2009 Ménard C, Yeung I, Chung P, Crook J, Damyanovich A, Haider M, Jaffray D, Lockwood G, Milosevic M. MRI Guided and Tumor Targeted HDR brachytherapy for recurrent prostate cancer. Natural Institute of Health. $272,240. 2007 - 2009. Ménard C, Sun A. Hippocampal Radiation Exposure and Memory: A Pilot Study. Brain Tumour Foundation, $ 25,000. 2007 - 2008 Milosevic M, Fyles A. Biologically-targeted, image-guided radiotherapy for cervix cancer. Giovanni and Concetta Guglietti Family Cancer Fund and the Princess Margaret Hospital Foundation. $250,000. 2005 - 2007. Milosevic M, Oza A, Brade A, Knox J. A phase I/II study of Sorafenib and palliative radiotherapy in patients with advanced renal cell carcinoma and symptomatic bony metastases. Bayer. $114,000, 2008. Morton G, Loblaw DA, Sankreacha R, Gardner S: Phase II study of single fraction High Dose-Rate (HDR) brachytherapy and hypofractionated external beam radiotherapy in men with intermediate risk carcinoma of the prostate. Royal Victoria Hospital Foundation “Motorcycle Ride for Dad”. $60,000, 2007 Moulder J, Hill R. Mitigating and treating the effects of radiation in lung tissue. National Institute of Allergy and Infectious Diseases. $1,259,165. 2005 - 2010. Nathan A, Rowlands JA, Kasap SO, Karim K. Novel approaches to flat panel detectors. Natural Sciences and Engineering Research Council. $162,000. 2004 - 2007. Nyhof-Young J, Johnson I. Promoting research excellence: The DOCH 2 47 Research Grants Cont’d… website for medical students. Information Technology Course Development Fund, University of Toronto. $20,000. 2006 - 2009. Okunieff P, Hill R. Assessing skin exposure by measuring DNA damage in skin cells. National Institute of Allergy and Infectious Diseases. $1,240,210. 2005 - 2010. O’Sullivan, B, Bell RS, Bristow R, Catton C, Davis AM, Ferguson PC, Hill RP, Jaffray DA, Kandel RA, Sharpe M, White L, Wunder JS. A phase II study of pre-operative Intensity Modulated Radiation Therapy for lower limb soft tissue Sarcoma. Ontario Cancer Research Network. $228,235. 2005 - 2008. Oza A, Milosevic M et al. Early therapeutics development with a phase II emphasis. NIH/NCI Investigational New Drug Phase II Consortium. National Cancer Institute, Cancer Therapy Evaluations, Division of Cancer Treatment and Diagnosis. $1,495,000 USD per year. 2006 - 2008. Pang G. Development of a novel Cerenkov x-ray detector for image-guided radiotherapy. Natural Sciences and Engineering Research Council. $100,000. 2005 - 2011. Pang G. Cerenkov X-ray detector for portal imaging. IPM MTCC Seed Grant. $13,333. 2007. Pang G, Rowlands JA, O’Brien P. Near real time cone beam digital tomosynthesis. Siemens Oncology Care Systems. US$50,000. 2007 -2008. Pang G, Kasap S. A rapid and low dose megavoltage x-ray topographic imaging system for image-guided radiotherapy of lung cancer. Canadian Institutes of Health Research. Operating grant. $87,376. Pignol JP. A phase IV trial of a permanent breast seed implant. Sunnybrook Health Sciences Centre Foundation. $93,000. 2008 - 2009. Pignol JP, Caldwell C, Keller B, Beachey D, Reznik A: Online gammacamera imaging of 103-palladium seeds (OGIPS) form permanent breast seed implantation. Canadian Breast Cancer Foundation – Ontario Chapter, $297,300. 2006 - 2009. Pignol JP, Rakovitch E, Caudrielier JM, Paszat L, Keller B, Cygler J. A Phase II study of adjuvant permanent breast seed implant (PBSI) for ductal carcinoma in situ (DCIS). Canadian Breast Cancer Foundation, Ontario Chapter. $448,340, 2008 - 2011. 48 Research Grants Cont’d… Pignol JP, Caldwell C, Czarnota GJ, Burns P, Mah K, Morton G, Rakovitch E, Rowlands J, Thomas G, Wong CS. Image guided brachytherapy. Sunnybrook Health Sciences Foundation. $1,892,980. 20072011. Penniment M, Wong R, Harvey J, Walpole E, Ngan S, Kneebone A, Beller E, Shakespeare T, Byram D. What is the value of radiotherapy in improving the quality of life of patients with advanced esophageal cancer? Does chemotherapy add value? A phase III international randomized trial. National Health & Medical Research Council Australia. $222,877. 2004 2008. Poon I, Enepekides D, Higgins K, Rosewell C. RAD51 Expression predicts radio sensitivity in squamous cell carcinoma of the head and neck and can be down-regulated by vitamin D3. RAZCER Award Grant. $16,873, 2007. Pritchard K, Paszat L, Seth A, Sutherland D, Zubovits J, Lyons-Weiler J. Gene profiling for prognostic and predictive factors in a breast cancer cohort. Canadian Breast Cancer Research Alliance. $898,860. 2004 - 2007. Rabeneck L, Paszat L. Risk of colorectal neoplasia following negative Nurse performed flexible sigmoidoscopy. American Society for Gastrointestinal Endoscopy. $44,875. 2004 - 2006. Rabeneck L, Paszat L, Bondy S, Stukel T, Law C, Hsieh E, Marshall D, McLaughlin J, Kim YI. Risk of advanced proximal neoplasia of the colon in asymptomatic adults. Canadian Institutes of Health Research. $932,659. 2005 - 2009. Rabeneck L, Paszat L. New or missed colorectal cancer after colonoscopy. American College of Gastroenterology. $176,000. 2007 - 2008. Rabeneck L, Paszat L. CIHR Team in population-based colorectal cancer screening. Canadian Institutes of Health Research. $2,443,467. 2007 - 2012 Rakovitch E, Paszat L, Hanna W, Pignol JP, Kahn H, Quan M, Wong J, Ackerman I. Lobular carcinoma in situ: A population-based analysis. National Cancer Institute of Canada. $585,545. 2006 - 2009. Rakovitch E, Paszat L, Hanna W, Pignol JP, Done S, Kahn H, Wong J, Goodwin P, Holloway C, Tuck A, Elavathil L, Gravel D, SenGupta S, Escott N, Bonin M, Quan ML, Zhang L. Predictors of local recurrence in ductal carcinoma in situ: a population based outcomes analysis. Canadian Breast Cancer Research Alliance. $1,284,373. 2007 - 2012. 49 Research Grants Cont’d… Reilly R, Pignol JP, Cai Z Allen C. X-ray activated and trastuzumabtargeted gold nanoparticles for radiotherapy of locally advanced breast cancer. Canadian Breast Cancer Research Alliance. $408,866. 2008 – 2011. Reznik A, Liu B, Rowlands JA. SHARP camera for positron emission mammography. Susan G. Komen Breast Cancer Foundation. $82,333 USD. 2004 - 2008. Reznik A, Rowlands JA. A novel high gain detector for breast cancer dedicated PET imager. Cancer Imaging Network of Ontario (CINO). $209,825. 2007 - 2009. Ritvo PG, Rabeneck L, Paszat L, Ferris L, Del Giudice L, Upshur R, Klar N, Katz J, Weitzman E. Addressing gender differences in colorectal cancer screening. Canadian Institutes of Health Research. $188,583. 2005 - 2008. Robert N, Rowlands JA. Image guided optimization of X-ray cardiac angiography. Canadian Institutes of Health Research. $76,258. 2005-2008. Robson S, Barker R, Barnes T. developing an advance practice radiation therapy role in palliative care: demonstration phase funding. Ministry of Health/via Advanced Practice for Radiation Therapy Project Oversight Committee. $72,000. 2007. Robson S, Barker R, Danjoux C. Developing an advance practice radiation therapy role in skin cancer: demonstration phase funding. Ministry of Health/via Advanced Practice for Radiation Therapy Project Oversight Committee. $72,000. 2007. Rosewall T, Catton C, Bayley A, Kelly V, Kong V. A prospective quantification of patient-reported adverse events following marker insertion and therapists matching variability within an established intra-prostatic marker program. Abbott-CARO Uro-Oncologic Radiation Award $12000, 2007. Rowlands JA, Zhao W, Pang G, Fahrig R. Low cost X-ray imaging using liquid crystals. National Institutes of Health. $225,000 USD. 2003 - 2008. Rowlands JA, Reznik A, Kasap SO. A novel solid-state PET detector for simultaneous PET and MR imaging. Canadian Institutes of Health Research. $341,256. 2006 -2009. 50 Research Grants Cont’d… Rowlands JA, Wright G, Cohen E, Fremes S, Fort S, Stewart D, Foster S, Burns P, Chauhan V, Wilson B. Imaging Research Centre for Cardiac Interventions. Canada Foundation for Innovation. $6,109,294. 2002 - 2008. Rowlands JA et al. Imaging research centre for cardiac interventions. Infrastructure Operating Fund. $1,800,000. 2006 - 2011. Sampson H, Brierley J, Heslegrave R, Jadad A, Michaelson T, NyhofYoung J, Panzarella T, Short D, Upshur T, Wiljer D. A study to assess the utility of a Canadian web-based research ethics board (REB) protocol and consent review template. Canadian Institutes of Health Research. $303,193. 2004 - 2007. Sanche L, Paquette B, Pignol JP. Investigations of low energy electron damage to cellular constituents: Application to radiotherapy. Canadian Institute of Health Research. $673,864. 2006 - 2010. Sewitch M, Barkun A, Rabeneck L, Paszat L, Hilsden R, Joseph L. Development and validation of a method to differentiate screening from surveillance and diagnostic colonoscopy in health administrative databases in three Canadian provinces. Canadian Institutes of Health Research. $100,000. 2006 - 2007. Shabbir A, Duff Canning S, Fleshner N, Krahn M, Naglie G, Tannock I, Tomlinson G, Warde P. A 2-year follow-up study of the health effects of androgen deprivation therapy in men with non-metastatic prostate cancer. CIHR and NCIC $120,000. 2007 - 2010. Siewerdsen JH, Brock KK. High-Performance cone-beam CT guidance of head and neck surgery. National Institutes of Health (NIH), R01 $760,000 (USD) 2007 - 2011. Siewerdsen J, Hamstra SJ, Jaffray DA. Investigation of imaging task and performance in fully 3-D volume computed tomography. University of Toronto, Dean’s Fund. $10,000. 2003 - 2008. Siewerdsen JH, Dawson LA, Paul PN, Jaffray DA, Burgess A, Fahrig R. Image science for the new X-ray: Taking NEQ to task. National Cancer Institute. $295,000. 2006 - 2010. Siewerdsen J. Development of advanced imaging applications with flatpanel detectors. Kodak Health Imaging. $300,000 USD. 2005 - 2007. Siewerdsen J. 3D cone-beam CT reconstruction. AAPM – Imaging Research Subcommittee Grant. $5,000 USD. 2007 - 2008. 51 Research Grants Cont’d… Siewerdsen J. High-Performance dual-energy imaging for diagnostic and image-guided procedures. Canadian Institutes of Health Research New Investigator Award $300,000. 2007 - 2012. Siewerdsen J. High-Performance dual-energy X-Ray imaging with flatpanel detectors – II. Industry Research Partnership – Kodak Health Imaging (Carestream Health Inc.) $500,000 USD (direct) $200,000 (capital) 2007 2009. Singh S, Paszat L. Waiting times for radiation therapy in Ontario and associated cancer outcomes. National Cancer Institute of Canada, $392,373, 2007 - 2010. Siu L, Fyles A, Milosevic M et al. Early clinical trials of new anti-cancer agents with phase I emphasis (U01). US National Cancer Institute. USD $3,141,916, 2007 - 2013. Solomon P, Orchard C, Hall, P, Baptiste S, Rukholm E, Luke R, Doucette S, Harrington M, Donio J. Institute of interprofessional health sciences education. Health Canada’s Pan-Canadian Health Human Resource Strategy for Interprofessional Education for Collaborative Patient-Centred Practice. $1,192,958. 2005 - 2008. Spayne JA, Holloway C, Pritchard K. Concurrent neoadjuvant chemoradiation for locally advanced breast cancer. Sanofi-Aventis, $400,000, 2006. Sullivan T, Paszat L. Improving continuity of care in the Ontario cancer care system: monitoring cancer services integration. Canadian Health Services Research Foundation. $100,000. 2004 - 2007. Sun A, Breen SL. A pilot prospective study of FDG-PET-CT imaging utility in radiotherapy treatment planning and assessment in all stages and histological types of lung cancer. Philips Medical Systems Canada. $124,000. 2006 - 2008. Szumacher E. Veronique Benk Professorship Grant – Education Sanofi Aventis $2,500, 2007. Szumacher E. Alon Dembo Professorship Grant–Education. Astra Zeneca. $16,000. 2007. Szumacher E. Education Grant. Abbott. $2500. 2007 52 Research Grants Cont’d… Szumacher E. Canadian patterns of practice in adjuvant radiotherapy for elderly women with stage I breast cancer survey. Astra Zeneca. $7,500. 2007. Szumacher E. Touch Pads Interactive Technology to improve interactivity at CME at the Radiation Program Odette Cancer Centre. Abbot Laboratories. $4000. 2007 Tang C, Loblaw DA, Klotz L The role of bound prostate specific antigen in predicting risk of progression in the active surveillance population with low risk localized prostate cancer. CUOG - AstraZeneca Fellowship Award. $9,940 2007 - 2008. Tinmouth J, Paszat L, Rabeneck L. Esophageal adenocarcinoma in Ontario: Trends, risk factors and health services utilization. Canadian Institutes of Health Research, $120,000. 2007 - 2009 Tinmouth J, Paszat L. Mortality from epidermoid anal cancer in the Province of Ontario. University of Toronto Dean’s Fund. $10,000. 2005 2010. Tsao MS, Bristow R, Done S, Hedley D, Hill R, Ikura M, Khokha R, Squire J, Wilson B, Wong CS, Bradley G. Equipment maintenance support for oncologic molecular micro-imaging. Canadian Institutes of Health Research. $400,000. 2005 - 2010. Tullio-Pow S, Barnwell S, Moore K, Nyhof-Young J. A victim of fashion? Investigating the apparel and accessories needs of female breast cancer patients at Princess Margaret Hospital. Ryerson University. $9,721. 2006 2008. Tullio-Pow S, Barnwell S, Moore K, Nyhof-Young J. Lymphedema lines: Designing functional apparel and accessories for female breast cancer patients at Princess Margaret Hospital. Ryerson University. $3,000. 2006 2007. Vallis, K Done S, Leong W, Woodgett J, McCready D, Knight J, MacGregor P, Broerner S. Breast cancer clinical research program. University Health Network. $800,000. 2004 - 2008. Vallis K, Rakovitch E, Bristow R, Koch A, Siminovitch K, Ozcelik H, Briollais L. Genetic polymorphisms and radiation sensitivity in breast cancer patients. Canadian Institutes of Health Research. $361,893. 2005 - 2008. van der Kooy D, Brown AS. Retinal stem cells for transplant in a glaucoma 53 Research Grants Cont’d… model. National Glaucoma Research, American Health Assistance Foundation. $90,000 USD. 2006 - 2008. Vitkin A. Towards cellular and microvascular subsurface tissue imaging invivo using optical coherence tomography. Premier’s Research Excellence Award. $150,000. 2003 - 2008. Shabbir A, Duff Canning S, Fleshner N, Krahn M, Naglie G, Tannock I, Tomlinson G, Warde P. A 2-year follow-up study of the health effects of androgen deprivation therapy in men with non-metastatic prostate cancer. CIHR/NCIC, $120,000. 2007 - 2010. Krahn M, Alibhai S, Ritvo P, Laporte A, Tomlinson G, Naglie G, Trachtenberg J, Pham B, Warde P. Androgen deprivation therapy in prostate cancer patients: patterns of care, lifetime costs, and cost effectiveness of ADT treatment. CCS Research Grant, $326,774, 2007 – 2010. Whelan T, Levine M, O’Malley F, Andrulis I, Pritchard K, Lytwyn A, Elavathil L, Koru-Sengal T, Pignol JP, Hayes D. Identification of biomarkers that predict response to accelerated hypo fractionated radiation therapy in breast cancer. Canadian Breast Cancer Foundation Ontario Chapter. $445,454. 20072010. Weisel R, Vitkin A. The Regenerative Medicine Project (REMEDI) Infrastructure Grant. Canadian Foundation for Innovation $7,200,000, 2007 2010 Whelan T, Vitkin A. Optical monitoring and control of focal laser thermal therapy of prostate cancer. National Cancer Institute of Canada. $274,000 2007- 2010. Wiljer D, Urowitz S, Jadad A, Catton P. From populous to policy. Canadian Institutes of Health Research. $8,000. 2006 - 2007. Wiljer D, Urowitz S, Jadad A, Catton P. From populous to policy. Canada Health Infoway - Funding Program Workshop. $10,000. 2006 - 2007. Wiljer D, Catton P, Luke R, Urowitz S, Moore K. A feasibility study for online lymphedema care. Canadian Breast Cancer Research Alliance (DEX Grant). $47,550.64. 2006 - 2008. Wiljer D, Appatu E, Downey S, Fraser H, Leung M, Nyhof-Young J, Urowitz S, Weinstock S. Systemic therapy redesign: Patient engagement project, 2007. Princess Margaret Hospital Foundation and UHN Health Chair. $30,000. 2007- 2009. 54 Research Grants Cont’d… Wong CS. Tissue protective peptide in radiation–induced brain injury. Ariam Pharmaceuticals Inc. $10,6654. 2007 - 2008 Wong CS. Research Support. Sunnybrook Health Sciences Centre. $635,000. 2002 - 2007. Wong CS. Mechanisms of radiation injury in the central nervous system. National Cancer Institute of Canada. $749,546. 2005 - 2010. Wong CS, Hill RP. Mitigation of brain injury after radiation. National Institute of Health. $110,000 USD. 2006 - 2007. Wong CS. The neuroprotective role of erythropoietin in radiation-induced CNS Injury. Ontario Cancer Research Network. $175,631. 2005 - 2008. Wright G, Hetherington CR, Lupea D, Nicholas DB, Nyhof-Young J, Willan AR. Improving education and coping of scoliosis patients undergoing surgery and their families using e-health. $240,363. 2006 - 2009. Wright G, Rowlands J et al. Imaging for cardiovascular therapeutics. Ontario Research Fund (ORF), Research Excellence. $14,490,484. 2008 2013. Yaffe M, Brock KK. Pathology Validation. Ontario Institute for Cancer Research. $702,092, 2008 – 2012. Yeboah C. Development of magnetically-confined very high energy laseraccelerated electron beam therapy. University of Toronto Dean’s Fund. $10,000. 2006 - 2010. Yeung I, Cho YB. On-line perfusion measurement with contrast enhanced cone-beam CT in radiation therapy. Canadian Institute of Health Research. $109,628, 2007 - 2009. Yeung I, Siewerdsen J. Dynamic contrast enhanced cone-beam CT imaging for the breast. Princess Margaret Hospital Foundation Weekend Walkers Breast Cancer Innovation Fund Grant. $72,250, 2007. Yeung I, Dawson LA, Cho YB, Jaffray DA. On-line perfusion measurement with contrast enhanced cone-beam CT in radiation therapy. Canadian Institutes of Health Research. $110,000. 2007 - 2008. Zhao W, Rowlands JA, Pang. SAPPHIRE: A new flat-panel digital mammography detector with avalanche photoconductor and high-resolution field emitter readout. US Army. $300,000 USD. 2004 - 2007. 55 Research Grants Cont’d… Zhao W, Rowlands JA, Street R. Flat panel x-ray imaging detector with avalanche gain. National Institutes of Health (NIH) USA. $750,000 USD. 2003 - 2008. Zimmermann C, Moore M, Oza A, Leighl N, Krzyzanowska M, Bezjak A, Donner A, Rydall A, Rodin G. Randomized controlled trial of an early palliative care team intervention for patients with metastatic cancer. National Cancer Institute of Canada. $415,856. 2006 - 2009. 56 Publications Peer Reviewed Publications Aalders JG and Thomas G. Endometrial cancer - revisiting the importance of pelvic and para-aortic lymph nodes. Gyn Onc 104(1);222-231, 2007. Akbarpour R, Friedman SN, Siewerdsen JH, Neary JD, and Cunningham IA. Signal and noise transfer in spatiotemporal quantum-based imaging systems. J Opt Soc Am A 24(12): B151-64, 2007. Allen AM, Elshaikh M, Worden FP, Bradford CR, Teknos TN, Chepeha DB, Hogikyan ND, Dawson LA, Urba S, Wolf GT, Normolle D, Eisbruch A. Acceleration of hyperfractionated chemoirradiation Regimen for Advanced Head and Neck Cancer. Head Neck 29(2);137-42, 2007. Al-Mayah, Moseley J, Brock KK. Contact surface and material nonlinearity modeling of human lungs. Phys Med Biol 53: 305-17, 2008. Ahn H, Mousavi P, Chin LCL, Roth S, Finkelstein J, Vitkin IA, Whyne C. The effect of pre-vertebroplasty tumor ablation using laser-induced thermotherapy on biomechanical stability and cement fill in the metastatic spine. Eur Spine J 16 1171-8, 2007. Andrade-Souza YM, Ramani M, Beachey DJ, Scora D, Tsao MN, terBrugge K, Schwartz ML. Liquid embolisation material reduces the delivered radiation dose: a physical experiment. 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Canadian 99 Abstracts Cont’d… Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2: Suppl 2): 32 S9, 2007. Cho YB, Lim K, Lundin A, Kelly V, Xie J, Rehbinder H, Brock K, Moseley J, Stewart J, Fyles A, Milosevic M. Optimal adaptive IMRT strategy for cervix cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2: Suppl 2): 69, S20, 2007. Choo R, Danjoux C, Morton G, Szumacher E, Sugar L, Gardner S, Loblaw A, Cheung P, Choow C, Klotz . Comparing Gleason Scores (GS) between initial and following-up (F/F) biopsy in untreated, low to intermediate grade, clinically localized prostate adenocarcinoma (CLPA). Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S11-12, 2007. Choo R, Danjoux C, Morton G, Szumacher E, Sugar L, Gardner S, Loblaw A, Cheung P, Klotz L. How much does histological grade of follow-up biopsy differ from that of initial biopsy in untreated low to intermediate grade, clinically localized prostate cancer? American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3): S348, 2007. Chow E, Harris K, Fan G, Tsao M, Sze WM, Wu J. Meta-analysis of palliative radiotherapy trials for bone metastases. Clin Oncol 19(3): S26, 2007. Chow JCL, Grigorov G. Dosimetric uncertainty of small cutouts in electron radiotherapy: Monte Carlo dosimetry evaluation. American Association of Physicists in Medicine Minneapolis 2007. Med Phys 34:2443, 2007. Chow JCL, Grigorov G. Evaluation of the effect of electron beam obliquity in the lateral buildup ratio using Monte Carlo simulation. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84/2:S52, 2007. Chow JCL, Grigorov G, Jiang R. Dosimetry along edges of an irregular MLC field with different stepping angles. American Association of Physicists in Medicine Minneapolis, 2007. Med Phys 34:2443, 2007. Chow JCL, Leung M. Verification of a Monte Carlo-based treatment planning tool. Canadian Association of Radiation Oncology – Canadian 100 Abstracts Cont’d… Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84:S92, 2007. Chu W, Kolios MC, and Czarnota GJ. Functional imaging of apoptosis in human tumours with high-frequency ultrasound imaging and spectroscopy. Proceedings American Institute of Ultrasound in Medicine Annual Meeting, New York, 2007. Chu W, Craig T, Moseley D, Brock K, Bayley A, Catton C, Chung P, Gospodarowicz M, Milosevic M, Warde P, Ménard C. Evaluating daily cone-beam CT image-guided radiotherapy after prostatectomy: can we reduce the PTV margin? Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2) (Suppl 2): S44, A 151, 2007. Chung A, Ng D, Garraway C, Nyhof-Young J, Wong R. Evaluating the use of fact versus story based educational resources for patients and caregivers with brain metastases. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): Abstract 213 S61, 2007. Craig T, Ménard C, Keller H, Brock K, Sharpe M, Jaffray DA. MRI target definition requirements for radiation therapy of dominant intraprostatic lesions. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S1, 2007. Craig T, Ménard C, Keller H, Brock K, Rehbinder H, Lundin A, Eriksson K, Sharpe M, Jaffray DA. Targeting dominant intraprostatic lesions in the radiation therapy of prostate cancer. XVth International Conference on the Use of Computers in Radiotherapy Conference Proceedings Vol II p.423427, 2007. Craig T, Mornex F, Kubas A, Maillard E, Tse R, Eccles C, Kim J, Dawson LA. Change in child-pugh liver function following conformal radiation for patients with hepatocellular carcinoma. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3): S290, 2007. Crook JM, Fleshner N, Roberts C, Pond G. Long term sequelae following iodine 125 prostate brachytherapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): 54, 2007. 101 Abstracts Cont’d… Crook JM, Gillan C, Yeung I, Austen L, McLean M, Lockwood G. PSA kinetics and PSA bounce following permanent seed prostate brachytherapy.29th Congress of the Societé Internationale d’Urologie, Paris, France. Urol 70(Suppl 3A): 135-MP 18.01, 2007. Crook JM, Grimard L, Esche B, Pond G. Penile brachytherapy: results for 60 patients. 29th Congress of the Societé Internationale d’Urologie, Paris, France. Urol 70(Suppl 3A): 161 MP 21.03, 2007. Crook JM, Ludgate C, Malone S, Lim J, Eapen L, Bowen J, Lockwood G. Report of a multicentre Canadian phase III randomized trial of three months versus eight months neoadjuvant androgen deprivation prior to standard dose radiotherapy for clinically localized prostate cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): 36, 2007. Crook JM, Neill M, Le L, Studer G, McLean M, Pond G. The nature and extent of urinary morbidity in relation to prostate brachytherapy urethral dosimetry. 29th Congress of the Societé Internationale d’Urologie, Paris, France. Urol 70(Suppl 3A): 135-POS 03.96, 2007. Crook JM, Neill M, Le L, Studer G, McLean M, Pond G. The nature and extent of urinary morbidity in relation to prostate brachytherapy urethral dosimetry. CARO-COMP 2007 Annual Scientific Meeting Toronto. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): 22, 2007. Crook JM, Patil N, Zhou D, Eng B, Wallace K. A phase III randomized trial of meloxicam started either 1 week prior to or concurrent with iodine125 prostate brachytherapy to reduce post implant edema, catheterization rates and the severity of lower urinary tract symptoms. World Congress of Brachytherapy Annual Scientific Meeting, Boston. Brachytherapy 7(2) OR66, 115, 2008. Crook JM, Roberts C, Fleshner N. Long-term urinary outcome after Iodine 125 prostate brachytherapy. 29th Congress of the Societé Internationale d’Urologie, Paris, France. Urol 70 (Suppl 3A):302-POS-03.95, 2007. Crook JM, Roberts C, Fleshner N. Long term urinary outcome after Iodine 125 prostate brachytherapy. ABS 28th Annual Meeting, Chicago. Brachytherapy 6(2) OR-36, 90, 2007. 102 Abstracts Cont’d… Crook JM, Sabishkumar EP, Pond G, Aneja M. Association of rectal dose dosimetry and toxicity with body mass index after permanent brachytherapy for low risk prostate cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int Radiat Oncol Biol Phys 69(3):S329, 2228, 2007. Crook JM, Saibishkumar E, Pond G. Is body mass index a predictor for rectal dosimetry and toxicity in Iodine 125 prostate brachytherapy. Embracing Excellence in Prostate and Kidney Cancer 1st Multidisciplinary Meeting on Urological Cancers, Barcelona, Spain 2007. EMUC p43:P17, 2007 Crook JM, Sabishkumar E, Yeung I, Borg J., Beiki-ardakani A., Cumminsholder C., Landon A. Comparison of rectal wall dosimetry of loose seeds and stranded seeds in Iodine 125 prostate brachytherapy. Embracing Excellence in Prostate and kidney Cancer 1st Multidisciplinary Meeting on Urological Cancers, Barcelona, Spain. EMUC, p102:P76, 2007. De Silva S, Waldron J, Norman, A., Cummings B, Dawson L., Keller A, Ringash J, Yu E, O'Sullivan B. Does contrast aid delineation of targets for radiotherapy in head and neck cancer (HNC)? 9th Biennial ESTRO Meeting on Physics and Radiation Technology for Clinical Radiotherapy. Radiother Oncol 84(Suppl 1): S263, 610, 2007. de Perrot M, Feld R, Anraku M, Bezjak A, Burkes R, Hoberts H, Cho J, Visbal A, Leighl N, Keshavjee S, Johnston M. Impact of induction chemotherapy and adjuvant radiation therapy on outcome after extrapleural pneumonectomy for malignant pleural mesothelioma. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. J Clin Oncol 25(18S):436S, A7708, 2007. Dahele M, Hwang D, Peressotti C, Sun L, Kusano M, Okhai S, Darling G, Yaffe M, Caldwell C, Mah K, Hornby J, Ehrlich L, Raphael S, Tsao M, and Ung Y Radiological-pathological correlation in non-small cell lung cancer: developing 3D methodologies for examining radiation target delineation. Radiother Oncol 84(Suppl 2):S57, 2007. Dahele M, Hwang D, Peressotti C, Sun L, Kusano M, Okahi S, Darling G, Yaffe M, Caldwell C, Mah M, Hornby J, Ehrlich L, Raphael S, Tsao M, Ung, Y. Radiological-Pathological Correlation (RPC) in non-small cell lung cancer, (NSCLC): developing three-dimensional (3-D) methodologies for examining radiation target volume delineation. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. 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Dawson L, Brock KK, Moulton C, Moseley J, Ahmed S, Guindi M, Gallinger S, Haider MA. Comparison of liver metastases volumes on CT, MR and FDG PET imaging to pathological resection using deformable image registration. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3): S68, 2007. Damyanovitch A, Kirilova A, Crook JM. Magnetic resonance spectroscopyobserved metabolic activity in prostate during PSA bounce following iodine125 brachytherapy. World Congress of Brachytherapy Annual Scientific Meeting, Boston. Brachytherapy 7(2) PL-1, 91, 2008. Desai S, Vanderberg A, Nyhof Young J. Looking beyond: an assessment of the spiritual needs of breast cancer patients undergoing treatment at Princess Margaret Hospital. U of T Med J 84(Suppl): S32 (HC6), 2007. Dickie CI, Parent AL, Griffin AM, Chung PW, Catton CN, Wunder JS, Ferguson PC, Sharpe MB, O'Sullivan B. Bone fractures following external beam radiotherapy and limb preservation surgery for extremity soft tissue sarcoma: relationship to irradiated bone length, volume and dose. American 105 Abstracts Cont’d… Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69, 3, S745-S746, 2007 Di Prospero L, Palmer C Innovative curriculum in a Canadian undergraduate medical radiation sciences program: self-driven learning supporting interdisciplinary education and training for clinical practice. 4th Annual Toronto Radiation Medicine Conference: Interprofessional Working Practices and Adoption of Innovation King City. Can J Med Rad Tech, summer 38 (2): 45, 2007. Divanbeigi L, Studer G, Huang SH, Cummings BJ, Dawson LA, Kim J, Ringash J, O’Sullivan B, Jaffray DA. Correlating radiation-induced volumetric and DWI-ADC changes in major salivary glands using CT/MR. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2) (Suppl 1): S4, 2007. Eccles CL, Brock KK, Moseley J, Moseley D, Jaffray DA, Dawson LA. Variability in liver shape and impact on GTV position during liver stereotactic radiotherapy with abdominal compression. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3),S186, 2007. Eccles CL, Brock KK, Moseley DJ, Jaffray DA, Dawson LA. Reproducibility of liver position using abdominal compression to reduce breathing motion during radiotherapy. Can J Med Rad Tech 38(2):43, 2007. Eccles CL, Craig T, Dawson L. Estimated dosimetric impact of IGRT in liver SBRT with ABC. European Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Barcelona. EJC Supp 5(4) p 125-126, 2007. Eccles C, Haider E, Haider M, Dawson L. Preliminary evaluation of diffusion MRI to assess liver radiotherapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2):S4, A15, 2007. Eccles CL, Haider M, Dawson LA. Preliminary evaluation of diffusion MRI to assess liver radiotherapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S4, A15, 2007. Eccles CL, Marshall A, Bissonnette JP, Kim J, Dinniwell R, Tse R, Dawson L. IV Contrast 4DCT scans for treatment planning of liver 106 Abstracts Cont’d… metastases. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting Toronto. Radiother Oncol 84(2): S62, A217, 2007. Eccles C, White E, Moseley DJ, Bissonnette JP, Dawson LA. A dynamic multimodality image guidance process for liver cancer radiotherapy. Can J Med Rad Tech 38(2):41, 2007. Evans WK, Smith CA, Ung Y. Lung cancer guideline development in Ontario: impact on policy and practice. 12th World Conference on Lung Cancer, Seoul, Korea. J Thor Oncol 2(8), (Suppl 4): S837, 2007. Fahrig R, Siewerdsen J, Jaffray DA, Boone J. Cone beam CT workshop. American Association of Physicists in Medicine Minneapolis, 2007. Med Phys 34(6): 2605-2605, 2007. Fairchild A, Chow E, Goh P, Ghosh S, Barnes TE, Sinclair E, Barbera L, Tsao M, Danjoux C. Has the pattern of practice in the prescription of palliative thoracic radiotherapy changed between 1999 and 2006 at the Rapid Response Radiotherapy Program? Supportive Care in Cancer. 20th International Anniversary Symposium, St Gallen, Switzerland. Supportive Care in Cancer 15(6): 745, #P-136, 2007. Fairchild A, Harris K, Wong R, Barnes T, Cheung P, Lutz S, Bezjak A, Chow E. Palliative thoracic radiotherapy for lung cancer: a systematic review. Annual Scientific Meeting, American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3S): S32, A56, 2007. Franks KN, Bezjak A, Higgins J, Li W, Purdie TG, Brade AM, Cho J, Payne D, Jaffray DA, Bissonnette JP. Image-guided lung radiotherapy: bringing technology into routine clinical practice. American Society of Clinical Oncology Annual Scientific Meeting, Orlando. J Clin Oncol 25(18S): 691S, A18093. 2007 Franks KN, Bezjak A, Purdie TG, Bissonnette JP, Pearson S, Payne D, Cho J, Kane G, Sun A, Brade A, Jaffray DA. Early results of imageguided radiation therapy in lung stereotactic body radiotherapy (SBRT). Clin Oncol 19(3 Suppl): S10, 2007. Franks K, Pearson S, Purdie TG, Bissonnette JP, Payne D, Cho J, Kane G, Sun A, Brade AM, Jaffray DA, Bezjak A. Image-guided lung stereotactic body radiation therapy (SBRT): a short, safe, and effective treatment for inoperable early stage lung cancer. Canadian Association of 107 Abstracts Cont’d… Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84/2(Suppl 2): S36, A123. 2007. Franks KN, Bezjak A, Purdie TG, Bissonnette JP, Pearson S, Payne D, Cho J, Kane G, Sun A, Brade A, Jaffray DA. Early results of image-guided radiation therapy in lung stereotactic body radiotherapy (SBRT). SBRT Lung Meeting UK Clin Oncol 19(3l): S10, 2007. Franks KN, Purdie TG, Bezjak A, Moseley D, Pearson S, Jaffray DA, Bissonnette JP. Quantifying inter and intra-fraction tumor motion using respiration-correlated cone beam CT in lung stereotactic body radiotherapy (SBRT). American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3S):S489S490, A2519, 2007. Garraway C, Damaraju D, Ng D, Chung A, Bezjak A, Nyhof-Young J, Wong R. What we should say and how: evaluating a combined story and fact-based educational booklet for patients with brain metastases and their caregivers. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists. Annual Scientific Meeting Toronto. Radiat Onc 84(Suppl 2): Abstract 212 S61, 2007. Georg M, Souvenir R, Hope A, Pless R. Manifold Learning for 4D CT Reconstruction of the Lung. IEEE Computer Society workshop on mathematical methods in biomedical image analysis (MMBIA), Anchorage, 2008. Gillies C, Moline K. An instructional strategy to improve inter-rater reliability in the assessment and evaluation of student clinical performance. Teaching & Learning Symposium, University of Toronto, Toronto, 2007. Grigorov G, Barnett R, Chow JCL. Dosimetry limitations and a dose profile correction methodology for sliding window IMRT. American Association of Physicists in Medicine Minneapolis, 2007 Med Phys 34:2444, 2007 Grigorov G, Barnett R, Chow JCL. Prostate IMRT: Calculation of dynamic rectal NTCP based on motion of the rectum, rectal wall variability and rectum deformation. Proceedings in Xth EFOMP Congress, Pisa, Italy. First European Conference on Medical Physics P1-2, 2007. Grigorov G, Chow JCL. A novel algorithm for calculation of dynamic rectal NTCP. Radiother Oncol 84/2:S30, 2007. 108 Abstracts Cont’d… Grigorov G, Kron T, Bauman G, Chow JCL, Grigorov L, Rodrigues G, Yu E, Battista JJ, Van Dyk J. Helical tomotherapy: QA program for prostate total treatment time. Proceedings in Xth EFOMP Congress, Pisa, Italy. First European Conference on Medical Physics T3#1-1, 2007. Grigorov G, Yazdani N, Markel D, Chow JCL, Grigorov L, Barnett R. Sliding window IMRT: Dose rate and leaf velocity limitations. Proceedings in Xth EFOMP Congress, Pisa, Italy. First European Conference on Medical Physics, T3#2-4, 2007. Harnett N, Bolderston A, Catton P, Gospodarowicz M, Lewis DD, Smoke M, Wenz J, Whitton A. Developing advanced practice roles in radiation therapy: letting the evidence speak. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S14, A46, 2007. Harnett N, Wiljer D, Catton P, Jaffray D, Gospodarowicz M. What comes first: Interprofessional practice or interprofessional education? The 13th Ottawa International Conference on Clinical Competence, Melbourne, Australia. 2008 Herrera F, Lunt SJ, Fyles A, Milosevic M, Supiot S, Ran H, Bristow R, Hill RP. Sorafenib (BAY 43-9006) protects normal murine gut from radiation damage. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3: Suppl): S124, 2007. Hererra F, Fyles A, Maheshwari E, Milosevic M, Levin W, Manchul L, Pintilie M, Haider M. A prospective study of MR imaging prognostic factors in women with cervix cancer treated with chemo-radiation. ECCO Meeting, Eur J Cancer 5(4) 315, 2007. Herrera F, Lunt SJ, Fyles A, Milosevic M, Supiot S, Ran J, Zhao H, Bristow R, Hill RP. Sorafenib (BAY 43-9006) protects normal murine gut from radiation (RT) damage. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2: Suppl 2), S83, 2007. Herrera FG, Lunt SJ, Fyles A, Milosevic M, Supiot S, Ran J, Zhao H, Bristow R, Hill RP. Sorafenib (BAY 43-9006) protects normal murine gut grom radiation (RT) damage. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S293, 2007. 109 Abstracts Cont’d… Herrera F, Lunt SJ, Fyles A, Milosevic M, Supiot S, Ran J, Zhao H, Bristow R, Hill RP. Sorafenib (BAY 43-9006) protects normal murine gut from radiation (RT) damage. Int J Radiat Oncol Biol Phys 69(3 Suppl):226, S125, 2007. Heydarian M, van-Prooijen M, Islam M, et al. Determination of treatment margin for the CBCT-based intracranial stereotactic radiosurgery / radiotherapy. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys, 69:S683, 2007. Higgins J, Bezjak A, Franks K, Payne D, Cho J, Le L, Bissonnette JP. A retrospective comparison of carina and bone as registration landmarks for volumetric image-guided lung radiotherapy (RT). Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84/2(Suppl 2): S35-S36, A122, 2007. Higgins J, Bezjak A, Franks K, Payne D, Cho J, Le L, Bissonnette JP. Feasibility and reproducibility of cone-beam CT guided lung radiotherapy using registration to bone, carina, and tumor. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3S): S520, A2570, 2007. Hird A, Hadi S, Loblaw A, Wong R, Wu J, Chow E. Pain flare following radiotherapy for painful bone metastases: a joint effort of three cancer centers to determine the incidence. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): Abstract 209 S60, 2007 Hird A, Hadi S, Loblaw A, Wong R, Wu J, Chow E. Pain flare following radiotherapy for painful bone metastases: a joint effort of three cancer centres to determine the incidence. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3): S32 Abstract 57 2007. Hoisak JDP, Koh ES, Laperriere N, Ménard C, Jaffray DA. Multiparametric MR tissue classification of glioblastoma multiforme: identification of spatio-temporal patterns of tumour progression and treatment response. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(S2): S5, 2007. 110 Abstracts Cont’d… Hoisak JDP, Breen SL, Jaffray DA. Identification of image features contributing to a reduction in inter-observer target definition variation with FDG PET-CT of nasopharyngeal carcinoma. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Biol Oncol Phys 69(3): S644-S645, 2007. Huang SH, Hwang D, Lockwood G, O’Sullivan B. The predictive value of tumor thickness for cervical metastasis in squamous cell carcinoma of oral cavity: a meta-analysis of reported studies. 14th Annual European Cancer Organization (ECCO) Meeting, Barcelona, Spain. European Journal of Cancer Supplements 5(4): 325, 2007. Huang SH, Lockwood G, Irish, J. Ringash J, Kim J, Waldron J, Dawson L, Bayley A, Cummings B, O’Sullivan B. Management of verrucous carcinoma of larynx: a reappraisal of the role of primary radiation. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists (CARO-COMP) Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S-64, 225, 2007. Huang S, Lockwood G, Irish J, Ringash J, Kim J, Waldron J, Dawson L., Bayley A, Cummings B, O’Sullivan B. The truths and myths of radiotherapy for verrucous carcinoma of larynx. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3): S198, 1107, 2007. Hui B, Catton P, Nyhof-Young J. Telling our stories: an evaluation of Oncology Interactive™ Education Series (OIES) survivor stories by breast cancer patients at Princess Margaret Hospital. U of T Medical Student Research Day, U of T Med J 84(Suppl):S34(HC12), 2007. Hwang D, Vakilha M, Breen S, Thomas C, Dawson L. Bayley A, Ringash J, Kim J, Cummings B, O’Sullivan B, Waldron J. Determination of PTV margins for enlarged cervical lymph nodes based on changes observed in volume and location with daily on-line cone-beam CT during a course of radiation therapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2):S-24, 82, 2007. Hwang D, Vakilha M, Breen S, Thomas C, Dawson L, Ringash J, Kim J, Cummings B, O’Sullivan B, Waldron J. Temporo-spatial changes of enlarged cervical lymph nodes during head and neck cancer IMRT imaged with daily on-line cone-beam CT. American Society of Therapeutic Radiology and Oncology 49th Annual Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(Suppl 3):S420, 2007. 111 Abstracts Cont’d… Ishkanian A, Mallof CA, Ho J, Syed A, van der Kwast T, Milosevic M, Lam W, Bristow RG. High-resolution array CGH of intermediate-risk prostate cancer genomes. American Society of Clinical Oncology Annual Scientific Meeting, Chicago. J Clin Oncol 26 (suppl): abstr 5158. 2008. Islam M, Norrlinger B, Fan C, Smale J, Galbraith D, Heaton R, Jaffray DA. A novel quality assurance monitor for real-time verification of IMRT and IGART. American Association of Physicists in Medicine, Minneapolis, 2007. Med Phys, 34 (6):2559, 2007. Jiang R, Barnett R, Chow JCL, Chen J. Estimating rectal complication in prostate IMRT treatment planning using maximum dose gradient. American Association of Physicists in Medicine Minneapolis, 2007. Med Phys 34:2447, 2007. Jiang R, Barnett R, Chow JCL, Chen JZY. Evaluation of prostate IMRT treatment planning incorporating internal organ motion using a dose gradient analysis. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84/2: S68, 2007. Johnson L, Waldron J, Dawson L, Bayley A, Cummings B, Kim J, O’Sullivan B, Ringash J, Breen SL. The effect of registration volumes on positional residual errors assessed using cone-beam computed tomography in radiation treatment of head and neck cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiation Oncol Biol Phys 69(Suppl 3):S418, 2007. Johnson L, Waldron J, Dawson L, Bayley A, Cummings B, Kim J, O’Sullivan B, Ringash J, Pintilie M, Breen SL. The effect of registration volumes on residual errors assessed using cone-beam computed tomography in radiation treatment of head and neck cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2):S-65, 228, 2007. Johnson L, Waldron J, Dawson L, Bayley A, Cummings B, Kim J, O’Sullivan B, Ringash J, Breen SL. The effect of registration volumes on positional residual errors assessed using cone-beam computed tomography in radiation treatment of head and neck cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Biol Oncol Phys 69(3):S418, 2007. Kaminsky I, Breen SL Waldron JN, Bayley A J, Cummings BJ, Dawson LA, Kim JJ, O'Sullivan B, Ringash J. Frequency and predictors of parotid sparing in a cohort of patients managed with bilateral neck IMRT 112 Abstracts Cont’d… for head and neck cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3):S450, 2445, 2007. Kaminsky I, Breen SL, Waldron JN, Bayley AJ, Cummings BJ, Dawson LA, Kim JJ, O'Sullivan B, Ringash J. Frequency and predictors of parotid sparing in a cohort of patients managed with bilateral neck IMRT for head and neck cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 8(1)S66, A227, 2007. Kassam Z, Brierley J, Hughes R, Tsang Y, Hirji A, Ringash J, Harrison M. Dosimetric implications of elective nodal irradiation in adenocarcinoma of the pancreas head. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiation Oncol Biol Phys 69(Suppl 3):S310, 2007. Kassam Z, Mackay H, Buckley C, Brierley J, Kim J, Siu L, Swallow C, Fung S, Oza A, Ringash J. Adjuvant chemoradiation for gastric adenocarcinoma with infusional 5-fluorouracil and cisplatin: Update of a phase I study. American Society of Clinical Oncology. GI Cancer Symposium Proceedings, 2008. Kassam Z, Wysocka B, Brierley J, Dawson L, Gospodarowicz M, Catton C, Lockwood G, Ringash J. Late adverse events following abdominal radiation. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2)S37, A129, 2007. Keller H, Tsang R, Vines D, Breen SL, Lockwood G. Quantification of local tumor response to fractionated radiation therapy for non-Hodgkin's lymphoma using weekly 18F-FDG PET imaging. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Biol Oncol Phys 69(3):S538-539, 2007. Keller H, Vines DC, Breen S. Quantification of uptake volumes in PET images for treatment response monitoring: challenges and solutions. Med Phys 6: 2394-5, 2007. Kim JJ, Breen SL, Waldron JN, Bayley AJ, Cummings BJ, Ringash J, Dawson LA, Liu C, Huang S, O'Sullivan BA. Standardized nomenclature system for head and neck (H&N) IMRT contouring, planning and quality assurance. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3):S473, 2490, 2007. 113 Abstracts Cont’d… Kirilova A, Bana N, Choi P, Brock K, Haider MA, Lockwood G, Eccles C, Dawson LA. Three dimensional motion of liver tumours using cine-MRI compared to liver motion assessed at fluoroscopy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2)S1, A4, 2007. Koh ES, Hodgson DC, Nyhof-Young J, Milosevic M, Le L, Lau A, Catton P. Improving study design to enhance the success of longitudinal survivorship research studies. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2: Suppl 2):S51, 2007. Koh E, Hodgson DC, Nyhof-Young J, Milosevic M, Le L, Catton P. Undertaking longitudinal research studies with cancer survivors: Can these studies succeed long-term? American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. J Radiat Oncol Biol Phys 69(3:Suppl),S577, 2007. Koh ES, Hodgson DC, Nyhof-Young J, Milosevic M, Le LW, Lau A, Catton PA. Undertaking longitudinal research studies with cancer survivors: Can these studies succeed long-term? Royal Australian and New Zealand College of Radiologists 58th Annual Scientific Meeting, Melbourne, Australia. Australasian Radiology 51 Supp3:A88, 2007. Koh ES, Ménard C, Koisak J, Brock K, Moseley J, Yu E, Millar BA, Kassner A, Damyanovich A, Kirilova A, Keller A, Laperriere N. Utility of standard MRI in differentiating therapeutic response versus pseudoprogression during chemoradiation for Glioblastoma Multiforme. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(S2):S5, 2007. Kong V, Catton C, Rosewall T. Relationship between prostate volume and normal tissue dosimetric parameters in prostate hypofractionated radiotherapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S69, 2007. Kong V, Chung P, Rosewall T, Bristow R, Milosevic M. The use of XVI during Bladder radiotherapy–bony anatomy or soft tissue match? Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S42, 2007. 114 Abstracts Cont’d… Kong F, West B, Bonner J, Choy H, Gaspar LE, Komaki R, Sun A, Morris D, Wang L, Sandler HM, Movsas B. To investigate the dominant pattern of current practice in radiation therapy (RT) for lung cancer among members of American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting. 2007. Larson D., Ma L., Ames C., Chou D., Chuang C., Petti P., Huang K., Weinstein P., Sahgal A. Safe Spinal Cord and Cauda Equina Partial volume tolerances for spinous/paraspinous radiosurgery. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Rad Oncol Bio Phys 69(3):S1, 2007. Lau M, Laperriere N, Hodgson D, Millar BA. Salivary gland sparing in pediatric patients receiving radiotherapy for tumours arising within the posterior fossa: optimization of treatment technique to minimize parotid dose. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(S2): S85-86, 2007. Lebel S, Bezjak A, Irish J, Devins G. The psychosocial impact of stigma in lung cancer patients. Psycho-Oncology 17(Suppl 3): 1-5, 2008. Lee CW, Peter J, Martin J, MacRae R, Laurie S, Ung Y, Willman C, Soroka LD, Shepherd FA. A survey of Canadian practice in management of malignant pleural mesothelioma. 12th World Conference on Lung Cancer in Seoul, Korea. J Thor Oncol. 2(8)(Suppl 4): S606, 2007. Laperriere N, O’Callaghan C, Ding K, Roa W, Mason W, Cairncross G, Brandes A, Menten J, Phillips C, Fay M, Nishikawa R, Nomikos D, Winch C, Perry J. Rationale and design for a phase III randomized controlled trial in elderly patients with glioblastoma multiforme: NCIC CTG CE.6. 13th Biannual Canadian Neuro-Oncology Meeting, Banff, Alberta, 2008. Laperriere N, Sahgal A, Heydarian M, McGowan H, Payne D, Xu W, Michaels H, Simpson ER, Somani S. Fractionated stereotactic treatment of choroidal melanoma. Canadian Radiosurgery Society Meeting, MontTremblant, 2008. The Canadian Journal of Neurological Sciences 35, Number 3 386, 2008. Letourneau D, Vloet A, Wong R, Sie F, Bootsma G, Gospodarowicz M, Jaffray DA. Assessment of intra-fraction motion for on-line planning and delivery of radiotherapy for patients with spinal metastases. 9th Biennial ESTRO Meeting on Physics and Radiation Technology for Clinical 115 Abstracts Cont’d… Radiotherapy, Barcelona, Spain. Radiat Oncol 84 Suppl 1: Abst 98 S45, 2007. Li W, Moseley DJ, Bissonnette JP, Le L, Purdie T, Bezjak A, Kim J, Jaffray DA. Retrospective evaluation of setup reproducibility for thoracic and upper gastrointestinal radiotherapy through volumetric imaging: stability and dependence on immobilization. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(Suppl 3): S507-S508, 2007. Lim K, Chan P, Dinniwell R, Fyles A, Haider M, Cho YB, Jaffray DA, Manchul L, Levin W, Hill RP, Milosevic M. Cervix cancer regression measured using weekly MR imaging during fractionated radiotherapy: radiobiologic modeling and correlation with tumor hypoxia. American Society of Clinical Oncology, Chicago. J Clin Oncol, 25(18S): 285S, 2007. Lim K, Fyles A, Cho YB, Kelly V, Moseley J, Stewart J, Brock K, Xie J, Lundin A, Rehbinder H, Milosevic M. Impact of inter-fraction motion and dose accumulation in adaptive whole pelvic IMRT for cervix cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto, 2007. Radiother Oncol 84(2: Suppl 2): 124 S36, 2007. Lim K, Fyles A, Lundin A, Cho YB, Kelly V, Moseley J, Brock K, Stewart J, Rehbinder H, Milosevic M. Dose impact of inter-fraction motion on whole pelvis IMRT in cervix cancer. 14th Annual European Cancer Organization (ECCO) Meeting, Barcelona, Spain. Eur J Cancer 5: 319, 2007. Lim K, Fyles A, Lundin A, Cho YB, Kelly V, Moseley J, Brock K, Stewart J, Rehbinder H, Milosevic M. Adaptive whole pelvis intensity modulate radiotherapy for cervix cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Bio Phys 69(3: Suppl):S385, 2007. Lim K, Kelly V, Stewart J, Fyles A, Cho YB, Brock K, Xie J, Moseley J, Lundin A, Rehbinder H, Milosevic M. Impact of inter-fraction motion and dose accumulation in adaptive whole pelvis IMRT for cervix cancer. 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J Nucl Med 48:450P, 2007. Vlad R, Giles A, Kolios MC, and Czarnota GJ. Developing ultrasound techniques to monitor tumour response to radiotherapy. Proceedings American Institute of Ultrasound in Medicine (AIUM), Annual Meeting, New York, 2007. Vloet A, Letourneau D, Moledina S, Vavda A, Wong R, Jaffray DA, Gospodarowicz G. Feasibility testing of a quality assurance process for a cone-beam CT enabled online planning and treatment model for palliative radiotherapy. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting (poster presentation), Toronto. Radiother Oncol 84(Suppl 2): Abstract 216 S62, 2007. Vu T, Bosnic S, Mitera G, Paszat L, Rakovitch E, Spayne J, Pignol JP. Clinical and treatment-related factors associated with acute toxicity in postmastectomy radiation. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting. Int J Radiat Oncol Biol Phys 69(3): S226, 2007. Vu TTT, Olivotto I, Rakovitch E, Bezjak A, Gardner S, Pignol JP. The impact of acute skin toxicity and breast radiation technique on quality of life: results of a phase III trial. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S23, 2007. 128 Abstracts Cont’d… Waldron J, Ringash J, Bayley A, Cummings B, Irish J, Kim J, Pintilie M, Sellmann S, Warde P, O’Sullivan B. High incidence of prolonged percutaneous tube feeding in patients treated with hyperfractionated accelerated radiation therapy for advanced head and neck cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S64: A224, 2007. Waldron J, Ringash J, Bayley A, Cummings B, Irish J, Kim J, Pintilie M, Sellmann S, Warde P, O’Sullivan B. Factors predicting prolonged percutaneous tube feeding in patients treated with hyperfractionated accelerated radiation therapy for advanced head and neck cancer. 14th Annual European Cancer Organization (ECCO) Meeting, Barcelona, Spain. Eur J Cancer 5(4): 326, 2007. Wong J, Basran P, Tirona R, Lee CT, Loblaw DA, Cheung P: Interfraction motion of pelvic iliac blood vessels in men undergoing radical radiotherapy for prostate cancer. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69(3) Suppl: S377, 2007. Wong J, Fleshner N, Yeung I, McLean M, Crook JM. TURP and prostate brachytherapy: effect on urinary function. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): 147, 2007. Wong J, Basran P, Tirona R, Lee CT, Loblaw DA, Cheung P. Interfraction motion of pelvic iliac blood vessels in men undergoing radical radiotherapy for prostate cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2): S45 (Abstract 154), 2007. Wu X, Bissonnette JP, Eccles C, Taremi M, Craig T, Dawson L. The use of normal tissue equivalent uniform dose (EUD) objective in IMRT optimization for liver cancer treatment. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting Toronto. Radiother Oncol 84(Suppl 2): S31, 2007. Wysocka BA, Kassam Z, Lockwood G, Brierley J, Dawson L, Ringash J. Assessment of intra and interfractional organ motion during adjuvant radiochemotherapy in gastric cancer. J Clin Oncol 25(18S); 644S, 2007. Wysocka B, Moseley J, Lockwood G, Wilson G, Kirilova A, Haider M, Ménard C, Bissonnette JP, Brock K, Dawson LA, Ringash J. 129 Abstracts Cont’d… Assessment of non-respiratory stomach motion in fasting and postprandial states. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84 (Suppl 2): S2, 2007. Wysocka B, Moseley J, Lockwood G, Wilson G, Kirilova A, Haider M, Ménard C, Bissonnette JP, Brock K, Ringash J. Non-respiratory stomach motion in healthy volunteers. Eur J Cancer 5(4):125, 2007. Yan J, Bayley AJ, Kelly V, Chung P, Catton CN, Warde P, Rosewall T. Clinical validation of PTV margins used during dose escalated loco-regional IMRT to prostate, SV & pelvic lymph nodes. European Society for Therapeutic Radiology and Oncology ESTRO, 9th Biennial meeting on Physics & Radiation Technology. Barcelona, Spain, 2007 Yan, J, Rosewall T, Chung P, Catton CN, Warde P, Kelly V, Bayley AJ. A strategy for image guidance during loco-regional IMRT to prostate, SV & pelvic lymph nodes. American Society for Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles, 2007. Int J Radiat Oncol Bio Phys 69(3): 2007. Yu H, Caldwell C, Mah K, Mozeg D, Chong R, Poon I. Co-registered PET/CT based 3-D texture classification of head and neck cancer. Canadian Association of Radiation Oncology – Canadian Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(Suppl 2); S88, 2007. Yu H, Caldwell C, Mah K FDG PET/CT based feature analysis head Abstractsof Cont’d… and neck cancer for radiation targeting. SNM Meeting, J Nucl Med 49(Suppl 1): p382P, 2008. Yan J, Bayley AJ, Kelly V, Chung P, Catton CN, Warde P, Rosewall T. Clinical validation of PTV margins used during dose escalated loco-regional IMRT to prostate, SV & pelvic lymph nodes. 14th Annual European Cancer Organization (ECCO) Meeting, Barcelona, Spain. ECCO 14 - EJC Supp 5(4): P295, 2007. Yan J, Rosewall T, Chung P, Catton CN, Warde P, Kelly V, Bayley AJ.A strategy for image guidance during loco-regional IMRT to prostate, SV & pelvic lymph nodes. American Society of Therapeutic Radiology and Oncology Annual Scientific Meeting, Los Angeles. Int J Radiat Oncol Biol Phys 69, 3 Supplement, S345: 2256, 2007. Zhang B, Damyanovich AZ, StainsbyJ, Mikulis, D, Ménard C. Addressing the geometric integrity of 3T MRI for gamma knife stereotactic radiosurgery. Canadian Association of Radiation Oncology – Canadian 130 Abstracts Cont’d… Organization of Medical Physicists Annual Scientific Meeting, Toronto. Radiother Oncol 84(2): S2, 2007. Zwahlen D, Jezioranski, J, Chan P, Cho YB, Yeung I, Manchul L, Levin W, Fyles A, Milosevic, M. MRI-based brachytherapy treatment planning for cervix cancer. American Brachytherapy Society Annual Meeting. Brachytherapy 6(2), 83, 2007. Presentations Balogh, Judith Management of Head and Neck Cancer. OAMRT Central Section Education Day, Odette Cancer Centre / Sunnybrook Health Sciences Centre, Toronto. 2007 Barker, Ruth Deciphering Statistics – A Refresher for Radiation Science Professionals. Canadian Association of Medical Radiation Technologists Annual General Conference. Moncton. 2008 Statistics Refresher for Radiation Science Professionals. American Society of Radiologic Technologists Radiation Therapy Conference. Los Angeles, USA. 2007 Barnes, Elizabeth Palliative Radiotherapy. 3rd National Oncology Conference, Nicaraguan Oncology Association, Managua, Nicaragua. 2007 Bayley, Andrew Prostate IMRT/IGRT. IGRT Education Course, Princess Margaret Hospital, Toronto. 2007 Bezjak, Andrea Lung Radiation Planning – Heterogeneity Corrections or Not? CARO Workshop on Lung Radiation Planning, Toronto. 2007 Case Study – Locally Advanced Lung Cancer. The Joint Meeting of the 4th ISC International Conference on Cancer Therapeutics and the 7th Princess Margaret Hospital Conference: New Developments in Cancer Management. Toronto. 2007 Introducing IGRT: A Site-Based Approach – Lung Cancer. IGRT Education Course, Princess Margaret Hospital, Toronto. 2008 131 Presentations Cont’d… PMH experience with Image Guidance in conventional lung RT; PMH experience with Image Guidance in lung SBRT. Elekta/Synergy Research Meeting. Crawley, UK. 2008 Palliative Whole Brain Radiotherapy for Patients with Brain Metastases - A Decade of Research. Canadian Palliative Radiation Oncology Group (CPROG) monthly video-conference rounds. Toronto. 2008 Case Study – NCIC CTG MA.8. QOL Educational Workshop on Value Added of QOL analysis in NCIC CTG Clinical Trials. NCIC CTG Spring Meeting.Toronto. 2008 Advances in Radiation treatment of Lung Cancer. The Future of Radiation Therapy in the 21st Century CME Day at the Juravinski Cancer Center/McMaster University. Hamilton. 2008 Bissonnette, Jean- Phillipe Avancées Techniques pour la Radiothérapie du Poumon. Mercredi d’Oncologie series at the Centre Hospitalier Universitaire de Québec. Quebec. 2007 Errors – Why they Occur, and How to Minimize them (Part II); Quality Assurance for IMRT and IGRT. American Association of Physicists in Medicine Continuing Education, Minneapolis. USA. 2007 Quality Assurance of image-guidance technologies. Radiological and Medical Physics Society of New York . New York, USA. 2007 Quality Assurance for kilovoltage Cone-beam CT Image-guidance. Emerging Technologies in Radiation Therapy: Impact on the Community Practice Medical Physicist. Educational Symposium for the Clinical Medical Physicist, Southeast Chapter of the American Association of Physicists in Medicine. Birmingham, USA. 2008 Image Guided Radiotherapy for Lung Cancer. Scientific Association of Swiss Radiation Oncology. Lausanne, Switzerland. 2008 Developing an Enhanced Quality Assurance Program in Radiation Therapy. Radiation Treatment Seminar Series, Hamilton. 2008 Bolderston, Amanda The Art of Qualitative Inquiry. Canadian Association of Medical Radiation Technology Conference. Moncton, 2008 132 Presentations Cont’d… An Update on Radiotherapy Advanced Practice in Ontario. Durham Regional Cancer Centre Grand Rounds. Oshawa. 2008 An Update on Radiotherapy Advanced Practice in Ontario. Kingston Regional Cancer Centre Grand Rounds. Kingston. 2008 An Update on Radiotherapy Advanced Practice in Ontario. Windsor Regional Cancer Centre Grand Rounds. Windsor. 2008 Helping students with performance difficulties. Toronto workshop for radiation therapists. Toronto. 2008 Brade, Anthony Challenges in the Design of Early Phase Clinical Trials Evaluating Combinations of radiotherapy and molecularly targeted therapies. Princess Margaret Hospital Conference, Toronto. 2007 Breen, Stephen Analysis of Spatial Variability in a Multi-Observer FDG-PET-CT Study of Primary Head-and-Neck GTVs. Process Control for IMRT Dosimetry. A Software Tool for Multimodal Target Definition. ICCR International Conference on the use of Computer in Radiation Therapy. Toronto. 2007 Brierley, James Organ motion during preoperative chemoradiation for rectal cancer. World Congress on Gastrointestinal Cancer. Barcelona, Spain. 2007 Panel Member Colorectal Cancer Symposium, Update on General Surgery, University of Toronto, Continuing Medical Education. Toronto. 2007 Best Practice in Staging. Cancer Care Ontario Workshop for Clinical Mentors. Toronto. 2007 Stage Capture. Cancer Care Ontario, Juravinski Cancer Centre. Hamilton. 2007 Stage Capture. Cancer Care Ontario, Ottawa General Hospital. Ottawa. 2007 How to Stage. McLaughlin Durham Regional Cancer Centre. Oshawa. 2007 Staging Practices. Cancer Care Ontario, Stage Capture Project, Clinical Mentor / Health Records Leads Meeting. Toronto. 2007 133 Presentations Cont’d… Treatment planning for Rectal and Anal Cancers. Addenbrookes Hospital. Cambridge, UK. 2007 Thyroid Cancer a Radiation Oncologists Perspective Canadian Society of Nuclear Medicine Annual Scientific Meeting , Toronto. 2008. Bristow, Robert p53 Phosphorylation and Interactions with ATM following DNA damage. 13th International Congress of Radiation Research. San Fransico, USA. 2007 DNA Repair Foci as a Biomarker on DNA damage. Golden Horseshoe Meeting, MacMaster University. Hamilton. 2007 Hypoxia and DNA Repair as Factors in Prostate Cancer Progression and Aggression. Prostate Cancer Research Program 2007 IMPaCT Meeting. Atlanta, USA. 2007 Future of Prostate Cancer Research. Canadian Prostate Cancer Research Initiative - Forum. Toronto. 2007 Measuring residual DNA damage in situ as a clinical biomarker of molecular target inhibition in radiotherapy and chemotherapy trials. Making Connections: A Canadian Cancer Research Conference Celebrating NCIC's 60th Anniversary. Toronto. 2007 Measuring residual DNA damage in situ as a clinical biomarker of molecular target inhibition in radiotherapy and chemotherapy trials. Princess Margaret Hospital Annual Conference. Toronto. 2007 Prostate Cancer Radiotherapy: New Targets and Therapies. Canadian Prostate Cancer Research Initiative Workshop. Vancouver, British Columbia. January. 2008 A Critical Review of DNA Repair in Tumour Stem Cells. RTOG Translational Symposium on Stem Cells and Radiotherapy, RTOG Meeting. USA. 2008 PARP Inhibition And The Tumour Microenvironment. CERRO-ESTRO. Presentations Cont’d… Les Meunieres, France. 2008 Hypoxia and DNA-dsb in Tumor Cells: Implications for Genetic Instability and Novel Therapies. Gordon Research Conference. Ventura Beach, USA. 2008 134 Presentations Cont’d… DNA Repair in Murine Skin Models: Repair Foci as Biologic Dosimeters CBARMF-NIAIDS Retreat, Univesity of Rochester. New York, USA. 2008 Hypoxia and DNA Repair. American Association for Cancer Research Annual Meeting. San Diego, USA. 2008 Hypoxia, DNA Repair and New Therapies. Meet-the-Expert Session, American Association for Cancer Research Annual Meeting. San Diego, USA. 2008 DNA Repair and Tumour Hypoxia. International Tumor Micorenvironment Meeting. Miami, USA. 2008 Individualizing Cancer Therapy on the Basis of Intratumoral DNA Repair. Scientific Meeting of the Prostate Cancer Research Foundation of the United Kingdom. King City, UK. 2008 Brock, Kristy Presented on behalf of the Deformable Registration Accuracy Consortium – A Multi-Institution Deformable Registration Accuracy Study. Los Angeles, USA. 2007 Characterization of Deformation and Treatment Response in Cervical Cancer Patients. Canadian Association of Radiation Oncology - Canadian Association of Medical Physics. Toronto. 2007 A Biomechanical Model-Based Approach to Deformable Registration: Technical Developments and Applications. MICe. Toronto. 2008 Imaging for Treatment Planning: Abdomen. Radiologic Society of North America Annual Meeting. Chicago, USA. 2007 Image Registration of Image Guided and Adaptive Radiotherapy. CAROCOMP. Toronto. 2007 Imaging for Treatment Planning; The Great Debate: The Future of IGRT is… American Association of Physicists in Medicine Annual Meeting. Minneapolis, USA. 2007 Cashell, Angela Development of an In House Training Model for Cone Beam X ray Volumetric Imaging. Canadian Association of Radiation Oncology. Toronto. 2007 135 Presentations Cont’d… Catton, Charles Sarcoma Refresher Course. Canadian Association of Radiation Oncology Annual Scientific Meeting. Toronto. 2007 Radiation Proctitis Workshop: Risk factors. Canadian Association of Radiation Oncology Annual Scientific Meeting, Toronto. 2007 International Collaboration on the RADICALS trial. RADICALS launch meeting. Medical Research Council, London, UK 2007 IMRT prostate-Clinical implications. Peel Regional Cancer Centre IMRT symposium, Mississauga. 2008 Post-operative therapy for prostate cancer. GU Conversations, Mississauga. 2008 Radiotherapy in the 21st century-prostate cancer. Juravinski Cancer Centre Hamilton. 2008 Catton, Pamela Survivorship Programs: Building Bridges Building Communities. Veronique Benk Symposium, Toronto. 2007 Panelist: Young Women Living with Breast Cancer, Toronto. 2007 Charman, Patricia Tips to Thrive And Not Just Survive! Seminar for 1st year Radiation Therapy Clinical Students: Orientation to the Clinical Environment, Toronto. 2008 Cho, Young Bin Dosimetric comparison between Single iso-center and dual iso-center techniques for Gamma Knife Radiosurgery in Trigeminal Neuralgia. 14th International Meeting of the Leksell Gamma Knife Society. Quebec. 2008 Optimal Adaptive IMRT Strategy for Cervix Cancer. Canadian Association of Radiation Oncology Annual Scientific Meeting. Toronto. 2007 Inter-Observer Precision Of Cone-Beam CT Soft Tissue Matching and Contouring For Gynaecological Malignancies. Canadian Association of Radiation Oncology Annual Scientific Meeting. Toronto. 2007 136 Presentations Cont’d… Chow, Edward Are bone metastases from gastrointestinal primaries equally radiosensitive? 49th American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, USA. 2007. Measuring the impact of bone metastases on quality of life. How do we optimize prostate cancer outcomes? Panel discussion and interactive clinical cases. A second symposium on advanced GU malignancy: Optimizing clinical outcomes in prostate and renal cell carcinomas. 29th Congress of the International Society of Urology. Paris, France. 2007 Educational Session 412: Quality of life issues and the role for radiation therapy for the palliative care patient. American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, USA. 2007 Symptom clusters: concepts, measurement and opportunities for research. RTOG Scientific Meeting. San Diego, USA. 2008 Quality of life and pain flare in bone metastases. Grand Round. Royal Victoria Hospital. Barrie. 2008 Chow, James A Customized Radiation Sensor for the Study of Ionization Collection Efficiency, Symposium on Health Technology. Waterloo. 2007 Chung, Peter Closing the loop - Clinical Research in Prostate Cancer Radiotherapy Brampton Prostate Cancer Group. Brampton, Ontario 2007 Craig, Timothy Accuracy in Radiation Therapy: Current Achievements, Future Solutions. Fields Mathematics Institute, University of Toronto, Toronto. 2007. Crook, Juanita Early Stage Prostate Cancer Treatment Options. Guelph Prostate Cancer Support Group. Guelph. 2007. Prostate brachytherapy: Who Should Be Thinking About It and Why. Bramptom Us-Too, Brampton. 2008 Prostate Brachytherapy: Who Should Be Thinking About It and Why. Newmarket Man to Man Group, Newmarket. 2008 137 Presentations Cont’d… Best of Journals: Selected Articles on Prostate Cancer. Presenter and Moderator. ASTRO/ASCO/SUO Genito-urinary cancers symposium. San Francisco, USA. 2008 LDR Brachytherapy for Favorable Risk Prostate Cancer. 13th Annual Scottsdale Prostate Cancer Symposium. Scottsdale, USA. 2008 Hormonal Therapy plus Radiation for Intermediate Risk Prostate Cancer. 13th Annual Scottsdale Prostate Cancer Symposium. Scottsdale, USA. 2008 Use of MR spectroscopy to characterize metabolic activity during the benign PSA bounce following iodine 125 prostate brachytherapy. Final report of a randomized trial of 3 vs. 8 months neoadjuvant hormone therapy prior to standard dose radiotherapy for clinically localized prostate cancer. European Association of Urology 1st Multidisciplinary Meeting on Urological Cancers. Barcelona, Spain. 2007 Cummings, Bernard Cancer of the Anal Canal. Ninth Congress of the Radiotherapy Society of Brazil. Gramado, Brazil. 2007 Czarnota, Gregory Imaging Radiation Responses Using High - Frequency Ultrasound. Fraunhoffer Institute. Sankt Ingebert, Germany. 2007 Danjoux, Cyril Overview of Cancer Treatment – Annual Pain Preceptorship Program, TSRCC, Toronto 2002-2007. Odette Cancer Centre / Sunnybrook Health Sciences Centre. Toronto. 2007 Davey, Caroline Exploring personal and organizational factors that may influence radiation therapists’ participation in career management strategies. CAMRT Annual Conference.. Moncton. 2008 Dawson, Laura Radiology Pathology Correlative Study for Liver Metastases Using Deformable Image Registration. American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. San Francisco, USA. 2007 Image Guided Radiotherapy for Hepatocellular Carcinoma: Western Experience. Fifth International Meeting on Hepatocellular Carcinoma. Houston, USA. 2007 138 Presentations Cont’d… Iso-Toxicity based Stereotactic Radiotherapy for Primary and Metastatic Liver Cancer. The Methodist Hospital and Baylor College of Medicine Grand Rounds. Houston, USA. 2007 Technical Advances in High Precision Radiotherapy of Moving Tumors. Radiation Oncology Rounds. Baylor College of Medicine. Houston, USA. 2007 Individualized Stereotactic Radiotherapy for Primary and Metastatic Liver Cancer. MD Anderson. Houston, USA. 2007 Liver Image Guided Radiotherapy. Image Guided Radiation Therapy Educational Course. Toronto. 2007 Radiation Therapy for Hepatobiliary Malignancies. ASCO / ASTRO Gastrointestinal Cancers Multi-disciplinary Symposium. Orlando, USA. 2007 Evolution from IMRT to IGRT. American Society for Therapeutic Radiotherapy and Oncology IMRT Symposium. San Francisco, USA. 2007 Radiotherapy for Hepatobiliary Malignancies. Northwestern's GI Cancer Symposium Review. Chicago, USA. Highly Individualized SBRT for Primary and Metastatic Liver Cancer. Cleveland Clinic’s First International Symposium on Stereotactic Body Radiation Therapy and Stereotactic Body Radiosurgery. Orlando, USA. 2007 Stereotactic Radiotherapy for Primary and Metastatic Liver Cancer. MD Anderson Orlando. Orlando, USA. 2007 Individualized Stereotactic Radiotherapy for Hepatobiliary Malignancies. Best of ASCO GI 2007, Northwestern University. Chicago, USA. 2007 Image Guided Radiotherapy. Chicago Radiological Society. Rush University Medical Center. Chicago. 2007 IGRT for Upper Abdominal Malignancies, Biological Radiation Treatment Planning Symposium. Hallym University. Seoul, Korea. 2007 Individualized Stereotactic Radiotherapy for Hepatic Malignancies. Yonsei University, Seoul, Korea. 139 Presentations Cont’d… Individualized SBRT for Liver Cancers. 7th International Symposium on Image-Guided Stereotactic Body Radiation Therapy. Dallas, USA. 2007 Image Guidance in Liver Cancer. 3rd European Elekta Users Meeting. Sitges Spain 2007 Image Guided Radiotherapy. What? When? Why? And Why not? Motion Management in High Precision Radiotherapy; Stereotactic Body Radiotherapy; Adaptive Radiotherapy for head and neck Cancer; Technical Advances in Radiotherapy: The Liver Cancer Example; CT / Nuclear Medicine / Radiotherapy Conference. Gold Coast, Queensland, Australia. 2007 High Precision Radiation Therapy for Primary and Metastatic Liver cancer. Keynote Address - Australasian Gastro-Intestinal Trials Group Annual Scientific Meeting, Melbourne, Australia, 2007 Esophageal cancer Radiation Planning Workshop. Australasian GastroIntestinal Trials Group Annual Scientific Meeting. Melbourne, Australia. 2007 Image Registration for Radiotherapy Planning and Treatment. Educational Symposium. CARO Annual General Meeting. Toronto. 2007 Image Guided Radiotherapy; Keynote Lecture: Motion Management in Radiotherapy; Stereotactic Body Radiotherapy. VII Last Generation Radiotherapy Course. São Paulo, Brazil. 2007 Liver Cancer - Innovative Radiation Therapy Approaches that Avoid Major Surgical Resection, Presidential Symposium 2007 American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, California 2007 Multimodality Imaging – Fusion and Registration for Radiotherapy Planning and Treatment. Educational Symposium. American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, California 2007 In Room CT Panel. American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, California 2007 4DCT e-contouring Symposium American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting. Los Angeles, California 2007 140 Presentations Cont’d… Liver Cancer Radiotherapy. 4th ISC International Conference on Cancer Therapeutics and the 7th Princess Margaret Hospital Conference: New Developments in Cancer Management. Toronto. 2007 PMH Experience with Radiotherapy for Hepatocellular Carcinoma and Future Opportunities. CIHR Canadian-Taiwanese Workshop. Taipei, Taiwan 2007 High Precision Radiation Therapy in Hepatocellular Carcinoma, Radiation Oncology Grand Rounds, Department of Oncology, National Taiwan University Hospital. Taipei, Taiwan 2007 Motion Management in IMRT Panel. American Society for Therapeutic Radiotherapy and Oncology IMRT Symposium. Orlando, Florida. February 2008 Liver IGRT at PMH. Elekta Synergy Research Consortium. Crawley, UK 2008 Keynote Address - IGRT: A Physician’s Perspective; IGRT for Thoracic and Abdominal Cancers; IGRT debate: Volumetric IGRT is required for IGRT; Moderator: Image Quality is the Limiting Factor in IGRT; American Society for Therapeutic Radiotherapy and Oncology IGRT Symposium. Newport Beach, CA. 2008 Can Radiation Therapy Help Patients with Primary and Metastatic Liver Cancer? Radiation Oncology Palliative Care Rounds. Odette Cancer Centre / Sunnybrook Health Sciences Centre Toronto. 2008 Dinniwell, Robert Inguinal lymph node topography and vascular anatomy for the radiotherapy treatment planning of cancers of the vulva, anal canal, and penis: a threedimensional radiotherapy treatment-planning atlas. Annual Meeting of the Radiological Society of North America (RSNA). Chicago, USA. 2007 Eccles, Cynthia Preliminary Evaluation of Diffusion MRI to Assess Liver Radiotherapy. CARO-COMP 2007 Annual Scientific Meeting. Toronto. Do you see what I see? IGRT, the Radiation Therapist perspective. American Society for Therapeutic Radiotherapy and Oncology IGRT III, Newport Beach, USA. 2008 141 Presentations Cont’d… Estimated Dosimetric Impact of Image Guided Radiotherapy in Liver SBRT with Active Breathing Co-ordination 2nd Annual Radiation Therapist Research Symposium. Toronto. 2008 Role of the Research Radiation Therapist in Image Guided Radiotherapy (IGRT), Hamilton Regional Cancer Centre –MRT Week. Hamilton. 2007 Fyles, Anthony NCI US. Cervical Cancer State of the Science Meeting, Bethesda Maryland , 2007 What’s New in Gynecologic Cancer, Canadian Cancer Registry Professionals Workshop #27, Toronto. 2007 Gillies, Carol An Instructional Strategy to Improve Inter-rater Reliability in the Assessment and Evaluation of Student Clinical Performance, Teaching & Learning Symposium, University of Toronto, Toronto. 2007 Gospodarowicz, Mary Prognosis and Prognostic Factors in Cancer. Dept of Radiation Oncology, University of Zurich – Visiting Professor – July 2007 Treatment of diffuse of large B-cell lymphoma. Workshop on Aggressive Lymphomas, German Lymphoma Study Group. Germany. 2007 TNM and Cancer Staging. European Cancer Conference - ECCO Annual Meeting, Barcelona.2007 Testis Cancer – Cure Without Compromise - Keynote Speaker. First Canadian Germ Cell Cancer Consensus Meeting. Kingbridge, Ontario. Management of primary, refractory and recurrent diffuse large B cell and other aggressive lymphomas. Refresher course, American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting, Los Angeles. 2007 Case discussions in Hodgkin’s disease and non-Hodgkin’s lymphoma Audience Interactive Course 213. American Society for Therapeutic Radiotherapy and Oncology Annual Scientific Meeting, Los Angeles. 2007 Prognostic Factors and Cancer Staging. Image Guided Therapy in Urologic Cancers. Schiffer Exchange Program Visiting Speaker. ISCORT - Israel 142 Presentations Cont’d… Society of Clinical Oncology and Radiation Therapy Conference, Israel January 2008 Hodgkin Lymphoma Update: Making Treatment Decisions - telephone education program, Leukemia & Lymphoma Society of Canada Walking the Tightrope in Bladder Cancer – discussion session. ASCO GU Symposium, San Francisco, February 2008 Surveillance Programs in Testicular Tumours, Oncology Summit, Arlington, March 2008 MALT Gastric Lymphoma Trial, 11th Annual Meeting of the International Extranodal Lymphoma Study Group, Lugano, April 2008 Radiotherapy and chemotherapy for stage II seminoma, ESMO Symposium on Germ Cell Testis Tumours, Munich, Germany, May 2008 Communicating Risks. Second Cancers. ASCO Educational Symposium, Chicago, June 2008 Radiotherapy in Malignant Lymphoma. Meet the Professor Session. Case panel discussion. 10th International Conference on Malignant Lymphoma, Lugano, June 2008 Harnett, Nicole The Questions of Advancing Practice. International Conference on Advanced Practice in Radiotherapy & Oncology. Sheffield, UK. 2007 Radiation Therapy Advanced Practice – How did we get there and where are we now? OAMRT, 2007 Annual General Meeting. Hamilton. 2007 The Clinical Specialist Radiation Therapist: a “novel” therapy. Radiation Medicine Program Rounds, Toronto. 2008 Heydarian, Mostafa Target Volume Treatment Margin for the CBCT-based Intracranial Stereotactic Radiosurgery / Radiotherapy. CaRS conference, MontTremblant, 2008 Higgins, Jane Stereotactic Lung Radiotherapy; New Information Reforming Clinical Practice. Ongoing Invited Talks/Oral Presentation – IGRT Education, PMH, Toronto 2008 143 Presentations Cont’d… Geometric Accuracy in Cone-Beam CT Guided Lung Radiotherapy – What Should we Match to? 2nd RT Research Symposium, TMI, Toronto. 2008 A retrospective comparison of carina and bone as registration landmarks for volumetric image-guided lung radiotherapy (RT). CARO-COMP Annual Scientific Meeting, Toronto. 2007 Hill, Richard Effect of genistein diet on radiation response of rat lung. CMCR Annual Meeting by NIAID/NIH, Washington, DC. June 2007. The tumour microenvironment and metastasis ICRR, July 2007 Biomarkers Quantec Meeting. Madison, WI. October 2007. Cancer stem cells and metastatic disease. NIH Workhsop, Washington, DC. December 2007. Animal Models for Radiation Toxicity: Lung CMCR Animal Models Workshop, San Antonio, CA. January 2008. Discussion leader: Panel discussion - point/counterpoint RTOG Stem Cell Symposium, San Diego, CA. January 2008. Assessing skin exposure by measuring DNA damage in skin cells CBARMFI Retreat, Pittsford, NY. March 2008 Biodosimetry in Skin and Mitigation in Lung following radiation exposure Armed Forces Radiobiological Research Institute. Bethesda MD May 2008. Hodgson, David Radiation Therapy for Aggressive Histology Lymphoma: Appropriate Selection of RT. Annual Meeting of the American Society of Therapeutic Radiology and Oncology, Los Angeles, October, 2007. Modeling Second Cancer Risks: Importance of Sex and Age on Estimates of Risk. Workshop on Late Effects in Hodgkin Lymphoma Survivors. 7th International Symposium on Hodgkin Lymphoma. Cologne, Germany, November, 2007. Innovations in Radiation Therapy for Childhood Brain Tumours. b.r.a.i.n. child Foundation Educational Event. Toronto, April, 2008. Jaffray, David 144 Presentations Cont’d… The Newest Frontier in Research and Treatment. Image guided Radiology Professional Advisors Breakfast PMH Foundation, Toronto. 2007 Are we equipped to integrate and support technology in the RT setting? CARO: The Royal College of Physicians and Surgeons of Canada at the Meeting of the Canadian Association of Radiation Oncology, Toronto, 2007. Count on me Campaign. The Southlake Regional Health Centre Foundation. 2007 IGRT, Cone-beam CT Primer, IGRT Implementation Strategies, Exploring the Frontiers of Image Guidance, Princess Margaret Hospital, Toronto, Ontario, January, 2008 Detector characterization of Trixel (Pixium 4343) Flat Panel Imager & lead discussion Reliability & performance of Synergy, Crawley, UK, Elekta February, 2008 Novel Technologies for SBRT. Second International Symposium on SBRT and SRS, Cleveland Clinic, Florida, USA, February, 2008 High-Precision, Image-Guided Radiation Therapy. Toronto Frontiers of Radiation Medicine Research, Toronto, Ontario, March 26th2008 IGRT, Cone-beam CT Primer, IGRT Implementation Strategies, Exploring the Frontiers of Image Guidance .Princess Margaret Hospital, Toronto, Ontario, March 27-29, 2008 Advances in Radiation therapy for targets in the lung. 3rd Ontario Thoracic Cancer Conference, Niagara on the Lake, Ontario. March 29, 2008 Implementation and Advancement of the IGRT Paradigm University of Chicago, Chicago, Illinois, USA April, 2008 Radiosurgery of Spinal Lesions: New Technologies Opportunities. Spinefest Toronto, Ontario. April 18, 2008 Bring New Explorations in Nano-modulated Radiation Therapy: Gold or Pyrite? RMP Rounds Princess Margaret Hospital, Toronto, Ontario- April 24, 2008( teaching) Physics and Biology Reforming Clinical Practice in Radiation Therapy. Fifth Annual Toronto Radiation Medicine Conference: Global Perspectives, Local Outcomes. Kingsbridge, King City, Ontario. April 26-27, 2008. 145 Presentations Cont’d… Biological applications panel-speaker. AAPM FOREM, Washington University, St Louis, Illinois USA, USA, May 1-2, 2008 Future Developments in Radiation Physics to Improve Patient Care. CME Day Juravinski Cancer Centre- Hamilton, Ontario. May 9th, 2008 IGRT, Cone-beam CT Primer, IGRT Implementation Strategies, Exploring the Frontiers of Image Guidance. Princess Margaret Hospital, Toronto, Ontario, June 5-7, 2008 Integrating Diagnostic and Therapeutic Modalities, New Developments in Molecular Imaging for Translational Research for Clinical Applications. Dresden, Germany, Oncoray, June 19-22, 2008 Kelly, Vallerie The Distribution of Kolb Learning Styles Across Radiation Therapy, Physics and Oncology. European Interprofessional Education Network in health and social care (EIPEN) First International Conference, Krakow, Poland. 2007 Laperriere, Normand Pseudoprogression in High Grade Glioma after Radiotherapy and Temozolomide. 25th Annual Meeting of the Quebec Association of Radiation Oncology, Orford. 2007 Update on the NCIC-CTG EORTC Elderly GBM study. Temodal Canadian Research Update Meeting, Barcelona, Spain. 2007 Neuro-imaging: how can we identify pseudo-progression. Temodal Canadian Research Update Meeting, Barcelona, Spain. 2007 Pseudoprogression in high-grade glioma after radiotherapy temozolomide. Windsor Regional Cancer Centre, Windsor. 2007 and Glioblastoma Multiforme following concurrent RT/temozolomide: a multiparametric MRI study to examine pseudoprogression. London Regional Cancer Centre, London. 2007 Multiparametric MRI study following concurrent radiotherapy / temozolomide in glioblastoma. Juravinski Cancer Centre, Hamilton. 2007 Overview of best practices in Glioblastoma Multiforme. Southern Ontario Neuro-Oncology Group meeting, Toronto. 2007 146 Presentations Cont’d… Radiation Treatment in Neuro-Oncology. Neurosciences Symposium, Toronto. 2007 4th Annual Krembil Gamma Knife versus Linac: Friends or foes. Annual 2007 E Harry Botterell Lectureship in Neurosurgery, University of Toronto, Toronto. 2007 Pseudoprogression in High-Grade Glioma after concurrent radiotherapy and temozolomide: a multiparametric MRI study. Dr. H. Bliss Murphy Cancer Centre, St John’s. 2007 Multiparametric magnetic resonance imaging in patients undergoing concurrent temozolomide and radiotherapy. Temodar North American Advisory Board meeting, Tampa, USA. 2007 New methods of radiation delivery in childhood. Pediatric Oncology Group of Ontario Satellite Education Day, Toronto. 2008 Pseudoprogression and multiparametric MRI in patients with glioblastoma. Grand River Cancer Centre, Kitchener. 2008 Strategies for treatment and new frontiers in elderly patients with GBM. IVth International Conference on Future Trends in the Treatment of Brain Tumors, Bologna, Italy. 2008 Optimum management for newly diagnosed GBM – does it make a difference to quality and duration of life? Optimum Management of Adult Gliomas in Ireland: Obtaining Consensus, Royal College of Physicians. Dublin, Ireland. 2008 Imaging and defining progression: Introduction to various imaging techniques. Temozolomide International Research Update Meeting. Geneva, Switzerland. 2008 Invited participant in NCI Consensus Meeting on Diffusion Weighted Magnetic Resonance Imaging as a Cancer Biomarker. Toronto, May 2008. Update on EORT-NCIC 4 year results; Pitfalls in response assessment. Current Trends in the Management of Malignant Gliomas II. Rio de Janeiro, Brazil, 2008 Update on the Elderly study; New approaches to understanding pseudoprogression. Temozolomide Canadian Research Update Meeting, Banff. 2008 147 Presentations Cont’d… Advances in the radiation management of pediatric CNS tumours. 13th Biennual Canadian Neuro-Oncology Meeting, Banff. 2008. Multiparametric MRI assessment of response in malignant gliomas. Update on Current and Future Approaches in the Management of Brain Tumours. London, UK, 2008 Pseudoprogression in Malignant Gliomas. Moving Forward in the Treatment of Brain Cancer: Developing a Local Neuroscience Service. Leeds, UK. 2008 Role of high dose radiotherapy in high grade gliomas. Current Trends in the Management of Malignant Gliomas II. Seoul, South Korea. 2008 Lightstone, Alexander Fractionated stereotactic treatment of brain metastases using Tomotherapy and image guided MVCT: follow-up on patients who could not be treated with radiosurgery. Canadian Radiosurgery Society Meeting. Mt. Tremblant, Quebec. 2008 Liu, Fei Fei Translational Research in Head & Neck Cancers. PMH/OCI 50th Anniversary Conference. Toronto. 2008 Loblaw, Andrew Improving functional outcomes of metastatic spinal cord compression through screening MRI and prophylactic radiotherapy (SMaRT). AO North America Spine Tumor Symposium. Vancouver, Sept 28, 2007 Current update on non-surgical treatments for prostate cancer. AO North America Spine Tumor Symposium.Vancouver, Sept 29, 2007 Mah, Katherine Advances in CT and PET Imaging for Radiation Treatment Planning Educational Course at ASTRO, San Francisco, USA. 2007. Manchul, Lee Innovative Strategies for Needs Assessment. Royal College of Physicians and Surgeons of Canada Annual Meeting. Winnipeg. 2007 Collaborations and CME: Educating and enhancing performance of the health care team. Presented to 20 participants at the Northeast Group on education Affairs, Association of American Medical Colleges Annual Educational Retreat. Burlington USA. 2008 148 Presentations Cont’d… Envisioning the New CME: better methods, better learning, better outcomes. Northeast Group on Education Affairs, Association of American Medical Colleges annual educational retreat. Burlington USA. 2008. Defining Educational scholarship in a Continuing Education/Professional Development Environment. Workshop delivered at the CME Congress. Vancouver. 2008 From strategic plan to scholarly activity: Moving beyond ideas to advance research and scholarship in CME. Poster presentation at the CME Congress, Vancouver. 2008 Ménard, Cynthia Targeted Radiotherapy in Urologic Cancer. Princess Margaret Hospital Conference. 2007 Image-Guidance for Radiotherapeutic Interventions in Prostate Cancer. NIH-NIBIB-NCIGT Workshop on Image-Guided Therapy. 2008 Milosevic, Michael Prostate cancer hypoxia in patients and the impact of androgen withdrawal: Implications for disease progression and radiation response. Presented at the Department of Defence Innovative Minds in Prostate Cancer Today (IMPaCT) Meeting. Atlanta, USA. 2007 Adapting to change: Opportunities and challenges for individualized radiotherapy. XV International Conference on the use of Computers in Radiation Therapy. Toronto. 2007 Adapting to change in cervix cancer. Department of Radiation Oncology, University of California, San Diego, USA. 2007 Canadian Radiation Oncology and CARO. European Society for Therapeutic Radiology and Oncology (ESTRO) Board Meeting. European Cancer Conference (ECCO) 14, Barcelona, Spain. 2007 Cervix cancer movement, regression and deformation during radiotherapy. Annual Scientific Meeting of the Canadian Association of Radiation Oncology, Toronto. 2007 Biologic enhancement of radiation response of radiation response in metastatic renal carcinoma. Canadian Kidney Cancer Forum, Tremblant. 2008 149 Presentations Cont’d… Functional imaging of tumor biology in clinical trials. Keynote Speaker, Annual Meeting of the Canadian Association of Medical Oncologists (CAMO). Toronto. 2008 Hypoxia and angiogenesis in cervix cancer. American Radium Society 90th Annual Meeting, Dana Point, USA. 2008 Radiotherapy and molecular targeting in the 21st century. Juravinski Cancer Centre Symposium: The Future of Radiation Therapy in the 21st Century, Hamilton. 2008 Hypoxia in prostate cancer: Implications for radiation and hormonal therapy. Visiting Professor, Juravinski Cancer Centre, Hamilton. 2008 Moline, Karen An Instructional Strategy to Improve Inter-rater Reliability in the Assessment and Evaluation of Student Clinical Performance, Teaching & Learning Symposium, University of Toronto, Toronto. 2007 An Instructional Strategy to Improve Inter-rater Reliability in the Assessment and Evaluation of Student Clinical Performance, Ontario Association of Medical Radiation Technologists Annual General Conference, Windsor. 2008 Percy Ghent Exhibit – Certificate of Merit Morton, Gerard High Dose-Rate Brachytherapy. Grand Rounds, BC Cancer Agency for the Southern Interior, Kelowna. 2008 Radiation Oncology Update. GU Oncology Experts Forum, Collingwood. 2008 HDR for Prostate Cancer. Nucletron Essentials in Brachytherapy Workshop, Baltimore, USA. 2008 Intensity Modulated Radiotherapy. Mater Private Hospital, Dublin, Ireland. 2007 Prostate HDR Brachytherapy: the nuts and bolts. Canadian Brachytherapy Group Workshop, Toronto. 2007 Moseley, Doug Emerging Technologies in Radiation Therapy: Impact on the Community Practice Medical Physicist An Educational Symposium for the Clinical 150 Presentations Cont’d… Medical Physicist. Southeast AAPM Chapter Meeting: Birmingham, USA. 2008 How does Evolving Technology influence Treatment Outcomes? 5th Annual Toronto Radiation Medicine Conference, Toronto. 2008. Nyhof-Young, Joyce An Assessment of the Spiritual Needs of Breast Cancer Patients Undergoing Treatment at Princess Margaret Hospital. Comprehensive Research Experience for Medical Students Research Day. 2007 O’Brien, Peter Safety First: Quality Assurance Standards at Canadian Radiotherapy Treatment Centres. Interdisciplinary rounds (IROR), Odette Cancer Centre / Sunnybrook Health Sciences Centre Centre. Toronto. 2007 Software, Radiotherapy and Risk Management. Mortality and Morbidity Rounds, G.I. Site Group, Odette Cancer Centre / Sunnybrook Health Sciences Centre. Toronto. 2007 O’Sullivan, Brian Radiotherapy of soft tissue Sarcoma. Education Course. American Society of Clinical Oncology. Chicago, USA. 2007 Nasopharyngeal carcinoma: State of the Art in Multimodality Treatment. Catholic University of Louvain, St - Luc University Hospital, Head and Neck Oncology Program. Brussels, Belgium. 2007 Management Dilemmas of Incurable/Recurrent Head and Neck Cancer. 9th Annual Scientific Meeting of the Australia New Zealand Head and Neck Society. Brisbane, Australia. 2007 Evolving knowledge about the biology and management of Nasopharyngeal Carcinoma. Princess Alexandra Hospital Cancer Collaborative Group 2007 Seminar Series. Brisbane, Australia. 2007 Evolving tools for Guidance in decision making, treatment delivery and post treatment surveillance in the management of NPC.East-West Symposiumon Nasopharyngeal Carcinoma. Twin Waters Resort, Sunshine Coast. Australia. 2007 Round Table Discussant: Intricacies of RT technique and delivery of NPC with Drs June Corry, Anne Lee, and Joseph Wee. East-West Symposium on Nasopharyngeal Carcinoma. Twin Waters Resort, Sunshine Coast. Australia. 2007 151 Presentations Cont’d… Multidisciplinary Collaborative Approaches for Planning and Delivery of Radiotherapy for Soft Tissue Sarcoma. Presidential Symposium on “Organ and Function Preservation in the Management of Cancer. 49th Annual Meeting of the American Society of Therapeutic Radiology and Oncology, Los Angeles, USA. 2007 Soft Tissue Sarcoma in Panel: “Masters of Radiation Oncology”. 49th Annual Meeting of the American Society of Therapeutic Radiology and Oncology. Los Angeles, USA. 2007 Multidisciplinary Collaborative Approaches for Planning and Delivery of Radiotherapy for Soft Tissue Sarcoma. 49th Annual Meeting of the American Society of Therapeutic Radiology and Oncology, Los Angeles, USA. 2007 Education Course: Nasopharynx Cancer, 49th Annual Meeting of the American Society of Therapeutic Radiology and Oncology. Los Angeles, USA. 2007 Oncodiagnosis Panel Moderator, Coordinator, Speaker: Multidisciplinary Management of Soft-Tissue Sarcoma. With co-panelist Drs R Bleakney and P Ferguson. Radiological Society of North America. Chicago, USA. 2007 The Multidisciplinary Management of Soft-Tissue Sarcoma. Radiological Society of North America. Chicago, USA. 2007 Reaffirming the role of Pre-operative Radiotherapy in the management of Soft Tissue Sarcoma. Vancouver Cancer Centre, Radiation Oncology Rounds. University of British Columbia, Vancouver, 2007 Keynote Lecture: The Treatment of Locally advanced head and neck Cancer: current status and future directions” at the British Columbia Provincial Head and Neck Tumour Group Retreat. Vancouver. 2007 Molecular Targeting in Head and Neck SCC: observations, challenges, and opportunities. Hong Kong Head and Neck Society. Hong Kong, China. 2007 The Local Management of Soft Tissue Sarcoma;The Changing Management of Oropharyngeal Cancer. University of Hong Kong, Queen Mary Hospital, China. 2007 152 Presentations Cont’d… Staging and Prognostic Factors in NPC: from Ho to the UICC and AJCC. Inaugural Visiting Professorship Lecture, Department of Clinical Oncology University of Hong Kong, Queen Mary Hospital. 2007 Opportunities to optimize the local management of soft tissue sarcoma;NPC: Head and Neck’s most unusual mucosal cancer. Dept of Radiation Medicine, University of Wisconsin, Madison USA. 2008 The management of head and neck cancer in the era of Molecular Oncology. Irish Cancer Society Lecture, Irish Association for Cancer Research, Newcastle, Northern Ireland. 2008 Case-based Discussion: Target Delineation and IMRT planning of Postoperative radiotherapy for Soft tissue sarcoma”. Grupo de Sarcomas de la Sociedad de Oncologia Radioterapica (SEOR) (Spanish Radiation Oncology Sarcoma Group) – Aula Magna de la Casa de Convalescencia del Hospital Santa Creu y San Pau, Barcelona, Spain. 2008 Keynote Lecture: Treatment Strategies and Conformal radiotherapy in STS of the extremity. Combined Meeting of the Spanish Orthopedic Society and the Grupo de Sarcomas de la Sociedad de Oncologia Radioterapica (SEOR) Spanish Radiation Oncology Sarcoma Group) – Aula Magna de la Casa de Convalescencia del Hospital Santa Creu y San Pau. Barcelona, Spain. 2008 Paszat, Lawrence Helicobacter pylori: epidemiologia y oportunidades para prevencion del cancer gastrico. El tercero congreso de oncologia de Nicaragua, La prevencion de cancer entre los hombres. Universidad Nacional Autonoma de Nicaragua a Managua, Departemento de la medicina preventiva. Nicaragua. 2007 Pignol, Jean-Philippe Innovative Radiation Treatments for Breast Cancer Patients. Canadian Association of Radiation Oncology and Canadian Organisation of Medical Physicist Joint Public Lecture. Toronto. 2007 Permanent Breast Seed Implant. Plenary panel discussion.American Brachytherapy Society. Chicago, USA. 2007 Rakovitch, Eileen Controversies in Breast Cancer. University of Toronto, Surgical Update Symposium. Toronto. 2007 153 Presentations Cont’d… What is New in the Management of Early Breast Cancer. Perceptive from Surgical, Medical and Radiation Oncology. Toronto Surgical Oncology Rounds. Toronto. 2007 Epidemiology of DCIS. Progress in Pathology Rounds. Odette Cancer Centre / Sunnybrook Health Sciences Centre. Toronto. 2007 Ringash, Jolie Meet the Professor: Adjuvant Radiotherapy for Gastric Cancer: Is it Necessary? Gastrointestinal Cancers Symposium ASCO / ASTRO / SSO / AGA, Orlando, USA. 2008 Interpreting the Magnitude of QOL Changes. Visiting Professor. National Cancer Centre Singapore, Singapore 2008 Minimal Important Difference: Can we Generalize?” PROBE Kick-off Meeting, EORTC QOL Committee. Brussels, Belgium. 2008 Adjuvant Radiotherapy for Gastric Cancer: Why and How?. Visiting Professor. Juravinski Cancer Centre, Hamilton. 2008 Case Study #2: SR.2 NCIC Clinical Trials Group, Quality of Life Committee Educational Workshop. Toronto. 2008. Rowlands, John Noise, Quantum noise and Psychophysics: their role in medical imaging. University of Toronto Mississauga. Mississauga, 2008. Saghal, Arjun Partial Volume Tolerance of the Spinal Cord. 8th bi-annual International Stereotactic Radiosurgery Society. San Francisco, USA, 2007 Adjuvant Therapies Emerging Techniques in Radiation Oncology: Spine IMRT/Radiosurgery; Current Updates on Non-Surgical Treatments, Specific Tumor Types, What the Surgeon Needs to Know: Renal Cancer. AO Spine North America Spine Tumor Symposium. Vancouver, 2007 Spine radiosurgery for vertebral metastases: Current technologies and preliminary results from UCSF. 2007 E. Harry Botterell Lectureship in Neurosurgery. The Toronto Western Hospital, University of Toronto, Toronto, Toronto. 2007 154 Presentations Cont’d… Acoustic Neuroma and Radiation: Technology and Options. Acoustic Neuroma Socitety of Canada. 25th Anniversary Annual Meeting for Patients. London. 2008 Sharpe, Michael Image-Guided Radiation Therapy: Implications for Treatment Planning. Department of Oncology, Cancer Research Institute, Queen’s University, Kingston. 2007 Sheika, Aisha Facilitator – “Conflict in Professional Life” -An Inter-professional Workshop for Upper Year Medical, Nursing, and Social Work Students. University of Toronto. Toronto. 2007 Facilitator – “Preclinical Prep.” -Orientation Session for MRS Class of 2010 PCRT 120 – Patient Care in Radiation Therapy 1. Toronto. 2008 Siewerdsen, Jeffrey The New X-Ray: Advances in the Science and Application of Flat-Panel Detectors,” Department of Radiology, University of Chicago, Chicago USA. 2007 Image Quality in Cone-Beam CT. SAMS Educational Symposium, 49th Annual Meeting of the AAPM, Minneapolis, USA. 2007 Multi-Modality Medical Imaging. Continuing Education Symposium, 49th Annual Meeting of the AAPM, Minneapolis MN, USA. 2007 The Great Debate: The Future of IGRT is…? Scientific Symposium, 49th Annual Meeting of the AAPM, Minneapolis USA,. 2007. On the Noise-Power Spectrum of 3D Computed Tomography. Imaging Workshop, 49th Annual Meeting of the AAPM, Minneapolis USA. 2007. Guided Therapeutics (GTx): A Translational Research Program for Advanced Image-Guided Interventions. University Health Network Research Day, Toronto. 2007 Szumacher, Ewa Risk for clinical failure-strategies to facilitate academic success. AMEE, Trondheim, Norway, September 2007. Multiprofessional education short communication Trondheim, Norway, September 2007. 155 session. AMEE, Presentations Cont’d… Demonstrating interprofessional and collaborative roles for patient-centered care (PCC) in Radiation Medicine – a workshop model. First International European Interprofessional Education Network (EIPEN) Conference, Krakow, Poland, September 2007. Exploring interprofessional and collaborative roles for patient-centered care – workshop. CARO, Toronto, Ontario, October 2007. Improving access to radiotherapy services in the Simcoe-Muskoka region of Ontario-needs Assessment Study. CARO, Toronto, Ontario, October 2007. ASTRO, Los Angeles, October 2007. - ? 2 different presentations Ontario radiation oncology residents needs in the PGY – 1 year- residents’ perspective survey. CARO, Toronto. 2007. ASTRO, Los Angeles, October 2007. The Decision Making Process for Treatment of Prostate Cancer”. Wellspring, Toronto. 2007 Thomas, Gillian Moderator: Current and Future Trials Addressing Staging and Imaging in Cervical cancer NCI State of the Science Meeting , Cervical Cancer . Washington USA. 2007. ESA’s and Impact on Cancer and Thrombosis. Aarhus, Denmark. 2007 Treatment of Locally advanced Cervix Cancer. A State of the Art Gynecologic Cancer Symposium, Management of Cervix Cancer. Odense, Denmark . 2007 Optimal Therapy for High Risk Early cervical cancer; Management of Cervical Adenocarcinoma Stage IB2; Updates on Chemo- Radiation in Cervical Cancer .Worldwide Meta analysis; Optimal Management of Recurrent Cervical Cancer; Importance of Lymph Nodes in Early Endometrial Carcinoma; Management of Recurrent Endometrial Cancer. First Congress of Chilean Society of Gynecologic Oncology. Valdivia, Chile. 2007 Endometrial Cancer: Implications of Nodal Staging & Adjuvant Therapy. Jerzy and Nina Einhorn Memorial Lecture. Swedish Oncology Society, Stockholm. Sweden. 2007. 156 Presentations Cont’d… Perspectives in Gynecologic Oncology. FIGO Stage Ib2 Ca Cervix: Which Patients Should Receive Radiotherapy? Radiation Oncologist’s Perspective. Cannes ,France. 2008. Radiation Therapy, Chemotherapy and Cervical Carcinoma. Oncology Summit. Washington DC USA. 2008 Management of Cervical Carcinoma. Current Issues in Gynecologic Cancer. 40th Annual Southeastern Wisconsin Cancer Conference. Wisconsin, USA. 2008 Tsang, Richard Skin Cancer Management with Radiation Therapy. Medical Radiation Sciences Program, Michener Institute and University of Toronto. Toronto, September, 2007. Review of management of non-Hodgkin’s lymphomas, and modern definition of the involved field. Refresher Course, Joint Annual Scientific Meeting of the Canadian Association of Radiation Oncology and the Canadian Organization of Medical Physicists (CARO-COMP). Toronto, October, 2007. Educational Session #311: Management of primary, refractory and recurrent diffuse large B-cell and other aggressive Lymphomas. 49th Meeting of the American Society for Therapeutic Radiology and Oncology. Los Angeles, USA. 2007 Radiation Therapy Management in Non-Hodgkin’s Lymphoma. Seton Cancer Centre, St. Mary’s Hospital, Saginaw, Michigan, November 2007. Radiation therapy for localized MALT lymphomas. Eighth Annual Canadian Oncology Winter Conference (COWC), B.C. March, 2008. Ung, Yee CT, PET and Pathology: Validating Imaging to Improve Radiation Targeting in Non-Small Cell Lung Cancer; Regional Cancer Centre (RCC) and Community Hospital (CH) Collaboration: A New Paradigm For Lung Cancer (LC) Service Organization?; 8Fluorodeoxyglucose Positron Emission Tomography and Co-registered Computed Tomography for Radiation Treatment Planning In Lung Cancer: A Systematic Review; Lung Cancer Guideline Development in Ontario: Knowledge Transference and Practitioner Feedback. NCIC 60th Anniversary Meeting. Toronto. 157 Presentations Cont’d… Workshop: Image guidance and adaptive radiation therapy with tomotherapy: Canadian Experience, Tomotherapy for Upper Abdominal Malignancies: Gastric, Pancreas and Hepatobiliary. CARO Annual Meeting. Toronto. 2007 Pancreatic Cancer: Is it time for a paradigm shift to induction treatment? GI Site Group, Academic Presentation. Toronto. 2007 The Lung Site: We’ve come a long way but there’s still a long road ahead”! Lung Site Group. Academic Presentation. Toronto. 2008 Yeung, Ivan Comparison of image texture between dynamic contrast enhanced CT and RMI in cervix cancer. National Cancer Institute of Canada 60th Anniversary Conference. Toronto 2007. Vines, Doug PET-CT Research in Radiation Oncology at PMH. GE Healthcare MultiModality Educational Symposium, Niagara Falls, Ontario, September 15, 2007. PET/CT in Radiation Oncology. The Canadian Society of Nuclear Medicine 2008 Annual Scientific Meeting, Toronto, Ontario, April 24, 2008. Vitkin, Alex Structrual and functional tissue imaging with light. Canadian Organization of Medical Physicists Annual Meeting, co invited by CCPM. Quebec. 2008 Turbid polarimetry for photodianosis. Center for Optics, Photonics, and Lasers biomedical rounds, Universite Laval. Quebec. 2008 Biomedical optics – uses of light in medicine. Diffusion-Wave Technologies seminar, Mechanical Engineering , University of Toronto. Toronto. 2008. Polarimetry for photodiagnosis: what’s polarized light got to do with it? Harvard Medical School / Mass General Hospital Photomedicine Rounds (Boston, MA, USA, 2008) Photo mayhem: Doppler optical coherence tomography for real-time invivo tissue characterization. Lawson Imaging Institute, Medical Imaging Rounds (London, ON, Canada, 2008) Doppler optical coherence tomography: underlying physics, enabling technologies, and biomedical applications. University of Houston Biomedical Engineering seminar (Houston, TX, USA, 2008) 158 Presentations Cont’d… Dynamic treatment feedback with biophotonics: wither ‘blind’ thereapies? Image-Guided Therapeutics colloquium, University Health Network. Toronto. 2008 Plenary at the Saratov Fall Confeence: “Doppler optical coherence Tomography for endoscopic diagnosis and treatment monitoring; Course: Introduction to Biophotonics Saratov Fall Conference. Saratov, Russia. 2007 Useful metrics for PDT-induced microvascular shutdown -- the role of Doppler optical coherence tomography. General Physics Institute, Russian Academy of Sciences. Moscow, Russia, 2007 Issues and challenges in tissue turbid polarimetry. Laser Applications in Life Sciences conference. Moscow, Russia. 2007 Introduction to biomedical optics; Optical fiber sensors for biomedicine; Turbid polarimetry for photodiagnosis; Biomedical Doppler optical coherence tomography; Towards the quantification of low level laser therapy effects (and beyond) - the uses of Doppler optical coherence tomography Lecture Series & Talk. Universidade de Sao Paolo, Brazil, 2007 Waldron, John Factors predicting prolonged percutaneous tube feeding in patients treated with hyperfractionated acceleration radiation therapy for advanced head and neck cancer. European Society of Therapeutic Radiation Oncologists Meeting (ESTRO) Barcelona, Spain, September, 2007 Warde, Padraig State of the Art Radiotherapy for Prostate Cancer – Should Surgeons be Worried? New Ideas, Approaches and Techniques - Urology Update 2007. Toronto. 2007 Role of Radiation Therapy in Prostate Cancer" - Prostate Cancer Survivors Group, Markham. 2007. Current Concepts and Controversies in the Management of Clinical Stage I Seminoma Surveillance. GU Cancers Symposium, a Multidisciplinary Approach – San Francisco, USA. 2008 Wiljer, David Patient Destiny: The movement to bring patients closer to their health information and empowerment! Alberta Cancer Board, Alberta. 2007. 159 Presentations Cont’d… Patient Access to Electronic Medical records: Health System Shares Lessons Learned. National HIPPA Compliance Audio Conference, November 2007. Conference, Wired for Safety, Advancing Patient Safety through e-Health. Keynote address “Vision of the Future”. Ontario Hospital Association. January 2008 Patient Portals: The Delicate Balance Between Access and Privacy. Insight Information. 2008 Exploring New Models for Survivorship Care in Lymphedema: A Feasibility Study for Online Care. CBCRA Conference, Vancouver. 2008 Wong, C Shun The role of acid sphingomyelinase in apoptosis of neural progenitors and inhibition of neurogenesis after ionizing radiation. Society for Neuroscience, 37th Annual Meeting, San Diego, November 2007. Wong, Rebecca The management of dyspnea in advanced diseases: a systematic review. Accepted for oral presentation at the Canadian Hospice Palliative Care Conference, Hospice Palliative Care: At a Crossroads, Westin Harbour Castle Hotel in Toronto, Ontario, Canada, November 4 - 7, 2007. Palliative Radiation – the New Era. Palliative Care Rounds. Community Care Access Center, Toronto. Mar 05 2008 160 Awards 2007-2008 Faculty Education Awards Resident’s Award for Excellence in Resident Teaching Woodrow Wells MRS Classroom Teaching Award Katherine Mah MRS Clinical Supervision Award Gwen Llewellyn Siobhan McArdle MRS Research Supervision Award Maureen Engel MRS Guest Lecturer Award Ida Ackerman Postgraduate Classroom Teaching Award Patrick Cheung Postgraduate Advocacy & Mentorship Award Normand Laperriere Postgraduate Medical Education Research Supervision Award Robert Bristow The Cummings Leadership Award Edward Chow Faculty Research Awards Sustained Excellence in Research Award John Rowlands Outstanding Research Potential Award Kristy Brock Research Leadership Award Edward Chow Best Annual Research Performance Award Lawrence Paszat 161 Awards Cont’d… Other Awards and Honours Professional Recognition Award: Special Service Certificate. Ontario Association of Medical Radiation Technologists. Amanda Bolderston E. I. Hood Award Essay Competition Certificate of Merit. Canadian Association of Medical Radiation Technology Conference. Ottawa. Amanda Bolderston Razcer Award - Rapid AstraZeneca & CARO Evaluation of Radiomodifiers “Effect of AZD2171 on late radiation toxicities in critical normal tissues.” $16,873 Cdn Anthony Brade Radiation Medicine Program Education Award–PMH Research Supervisor Award 2007 Robert Bristow Virginia Logan Award Lecturer, Kimmel Cancer Center; Thomas Jefferson University 2007 Robert Bristow CAMRT Certificate of Merit Award in the Sister Mary Arthur; Sharing the Light award for a paper entitled “The Psychosocial Issues faced by men with testicular Cancer” 2007 Angela Cashell Mickles Fellowship Award, University of Toronto Postgraduate Medical Education 2008 Pamela Catton Radiation Medicine Program-PMH Research Productivity Award 2007 Juanita Crook Best Clinical Abstract Award CARO 2007 Juanita Crook National Cancer Institute of Canada’s Robert L. Noble Prize, Sponsored by the Canadian Cancer Society for Outstanding Achievements in Cancer Research 2007 Richard Hill Inventor of the year Award - University Health Network, Technology Development & Commercialization. Toronto, Ontario. 162 Awards Cont’d… David Jaffray Peter’s Boyd Academy Award for Clinical Teaching for 2006 - 2007, Faculty of Medicine, University of Toronto 2007 Juhu Kamra Outstanding Research Potential Award 2007 – Dept of Radiation Oncology, University of Toronto Cynthia Menard 48th Annual AAPM Reviewer’s Choice Session for Highly Rated Abstracts Doug Moseley The best paper award of the Symposium on Circuits, Devices and Systems of CCECE 2008 John Rowlands Michael B. Merickel Best Student Paper Competition, First Place. San Diego, Feb. 2008. Jeffrey H. Siewerdsen 163 Research Day – May 10, 2007 Presentations Gaurav Bahl, Radiation Oncology Fellow Reirradiation for Recurrent Meningiomas: Outcomes and Complications Supervisor: N. Laperriere Robert Case, Radiation Therapy Graduate Student Inter-and Intra-Fraction Variability in Liver Motion for Patients Receiving Stereotactic Liver Radiotherapy Supervisor: LA. Dawson Eva Christensen, Radiation Therapy Graduate Student Novel Blood and Protein Biomarkers of Radiotherapy Response in Prostate Cancer: a Longitudinal Proteomic Study. Supervisor: R. Bristow Supriya Chopra, Radiation Oncology Fellow Correlation of BOLD MRI with Measures of Tumor Hypoxia in Prostate Cancer Supervisor: C. Ménard Max Dahele, Radiation Oncology Fellow The Early Metabolic Response of Non-Small Cell lung Cancer (NSCLC) to Stereotactic Body Radiation Therapy (SBRT) Supervisor: A. Bezjak David Fitzpatrick, Radiation Oncology Fellow Online Palliative Radiotherapy Planning and Treatment using Cone-Beam Computerized Tomography (CBCT) Supervisor: R. Wong Matthew Follwell, Radiation Oncology Resident Neovascular Glaucoma Following Stereotactic Radiotherapy for Choroidal Melanoma: A Dosimetric Analysis Supervisor: A. Sahgal Adrian Ishkanian, Radiation Oncology Resident High-resolution Array CGH Identifies Novel Regions of Genomic Alteration in Intermediate-risk Prostate Cancer Supervisor: R. Bristow 164 Research Day Cont’d… Justin Lee, Radiation Oncology Fellow Ultrasound Microbubble-potentiated Enhancement of Tumour Response to Radiation Preliminary Results Supervisor: G. Czarnota Eric Leung, Radiation Oncology Fellow Effects of Radiotherapy on Tumour Interstitial Architecture and Fluid Dynamics Supervisor: M. Milosevic Gerald Lim, Radiation Oncology y Fellow A Pilot Prospective Study of Metabolic and Anatomic Response Using FDG PET CT Before, During and After Radiotherapy in Lung Cancer Supervisor: A. Sun Gerald Lim, Radiation Oncology Fellow Respiratory Correlated Cone Beam CT in the Assessment of Volumetric and Geometric Tumour Changes in Non-Small Cell Lung Cancer During Radiotherapy Supervisor: A. Bezjak Nikhilesh Patil, Radiation Oncology Fellow What Treatment Margins Should We Achieve with Iodine 125 Prostate Brachytherapy? Supervisor: J. Crook Nikhilesh Patil, Radiation Oncology Fellow Prospective Evaluation of Erectile Function Using International Index of Erectile Dysfunctions (IIEF-5) Score After Iodine-125 Permanent Prostate Brachytherapy. Supervisor: J. Crook Paul Sanghera, Radiation Oncology Fellow Pseudoprogression Following Chemoradiotherapy for Glioblastoma Supervisor: M. Tsao Hany Soliman, Radiation Oncology Resident The Dosimetric Significance of Catheter Displacement in Prostate High Dose-Rate Brachytherapy. Supervisor: G. Morton Hany Soliman, Radiation Oncology Resident Accelerated Hypofractionated Radiotherapy for Early-Stage Non-Small Cell Lung Cancer: Long Term Results. Supervisor: P. Cheung 165 Research Day Cont’d… Hany Soliman, Radiation Oncology Resident Preliminary Results of a Phase II Study of Single Fraction Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases Supervisor: L. Dawson Hany Soliman, Radiation Oncology Resident Monitoring Treatment Response in Locally Advanced Breast Cancer Using Pulsed Time-Domain Diffuse Optical Spectroscopy Supervisor: G. Czarnota Alina Sturdza, Radiation Oncology Resident Uncertainties in Assessing Sigmoid Dose Volume Parameters in MRI Guided Fractionated HDR-Brachytherapy for Cervical Cancer Supervisor: G. Thomas Qiulin Tang, Radiation Physics Fellow On-Line Dynamic Contrast Enhanced Cone-Beam CT for Measuring Changes in Tumor Perudion due to Radiation Therapy. Danny Vesprini, Radiation Oncology Fellow Clinical and Pre-Clinical Measures of Radiosensitivity in Male BRCA1/2 Carriers Receiving Radiotherapy. Supervisor: R. Bristow Fred Yoon, Radiation Oncology Resident Alterations in Hormone Levels After Adjuvant Chemoradiation in Male Rectal Cancer Patients. Supervisor: F. Perera Posters Gaurav Bahl, Radiation Oncology Fellow Atypical and Malignant Meningiomas: Long-term Results with Radiation Therapy. Supervisor: N. Laperriere Debashis Biswas, Radiation Oncology Fellow CT Breast Density Volumes and Improved Prediction of Breast Cancer Risk Supervisor: A. Fyles Elisa Chan, Radiation Oncology Resident Palliation by Low Dose Local Radiotherapy for Indolent Non Hodgkin’s Lymphoma Supervisor: RW. Tsang 166 Research Day Cont’d… Lee Chin, Radiation Physics Resident Assessment and Development of a Wedge-free Radiation Physics Program: Experience at Princess Margaret Hospital (PMH). Supervisor: M. Sharpe Lee Chin, Radiation Physics Resident Experimental and Pinnacle3 Evaluation of ModPTV Margins for DMPO Optimization in a Solid Water Cylindrical IMRT Phantom Supervisor: S. Breen Richard Clarkson, Radiation Physics Fellow A Phantom for CT/CBCT Breast Cancer Research Supervisor: I. Yeung Max Dahele, Radiation Oncology Fellow What is the Impact of a Multidisciplinary Thoracic Cancer Conference? Supervisor: Y. Ung David Fitzpatrick, Radiation Oncology Fellow Malignant Cord Compression: Identifying Patients Suitable for Surgery Supervisor: R. Wong David Fitzpatrick, Radiation Oncology Fellow Bone Metastases – Rapid Effective Visualization of Overlapping Treatments. (Bone Met REVOLT) Supervisor: W. Levin Jayant Goda, Radiation Oncology Fellow Long-term Outcome Following Radiotherapy in Localized Extranodal MALT Lymphomas Supervisor: RW. Tsang Dawit Assefa Haile, Radiation Physics Fellow Texture Analysis as a Potential Tool for Monitoring Radiation Treatment Response for Patients with Glioblastoma Multiforme Supervisor: I. Yeung Rick Holly, Radiation Physics Resident Image Guided Brachytherapy(IGBT) for HDR Prostate Treatment: PreTreatment Verification Using Conebeam Imaging to Determine Catheter Displacement Supervisor: G. Morton Frank Hoebers, Radiation Oncology Fellow 167 Research Day Cont’d… A Pilot Study to Evaluate Swallowing and Dysphagia after (Chemo-) radiation in Head and Neck Cancer Patients, Using Magnetic Resonance Imaging Supervisor: J Waldron Dylan Hunt, Radiation Physics Resident Design and Construction of a Contrast-detail Test Phantom for PET and SPECT Supervisor: C.Caldwell Asim Karman, Radiation Oncology Fellow Acute Toxicity of Single Fraction High Dose-Rate Brachytherapy with Hypofractionated External Beam Radiotherapy in Intermediate Risk Prostate Cancer Supervisor: G. 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