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Allison Del Bene Davis PhD, RN March 17, 2011 1 Learning Objectives To describe the impact of improper waste disposal To identify proper methods to dispose of medications 2 Excess meds in assisted living facilities ‐ a common issue Frequent changes in prescription medications Large amounts of over‐the–counter medications Repeated hospitalizations Expired medications Discontinued medications Unused medications Having unnecessary medications sitting around can cause confusion for the technician administering the medications and can potentially lead to medication errors. 3 Ways to minimize this in the first place Periodic review of all medications by the delegating nurse, primary care physician or pharmacist Discontinuation of medications that are not needed Discussion of non pharmacological management of certain conditions IE: Constipation: Adequate fluid intake, increased insoluble fiber intake, increased activity To limit the number of medications: ‐ Do not order the medications if they are not needed in the first place. ‐ Periodic reviews of the patient’s medications is a good way to minimize excess. ‐ Try non‐pharmacological interventions first, before prescribing drugs. 4 How we used to handle medication disposal Medications have traditionally been disposed of by flushing them down the toilet. Some have been returned to the pharmacy for credit if they were un‐opened. We used to flush drugs but are now leaning towards alternatives. The issue with flushing drugs down the toilet is that flushed medications do not go to “heaven” but get incorporated into our water system. You could also try to return untouched, unopened and unexpired medications to the pharmacy. 5 Medications and drinking water Pharmaceuticals and personal care products (PPCPs) are a source of water pollution: PPCPs of concern include: Prescription and over‐the counter therapeutic drugs Veterinary drugs Fragrances Cosmetics Sun‐screen products Diagnostic agents Nutraceuticals (e.g., vitamins) 6 Medication pollution in drinking water “Officials in Philadelphia said testing there discovered 56 pharmaceuticals or byproducts in treated drinking water, including medicines for pain, infection, high cholesterol, asthma, epilepsy, mental illness and heart problems” “Anti‐epileptic and anti‐anxiety medications were detected in a portion of the treated drinking water for 18.5 million people in Southern California.” “Researchers at the U.S. Geological Survey analyzed a Passaic Valley Water Commission drinking water treatment plant, which serves 850,000 people in Northern New Jersey, and found a metabolized angina medicine and the mood‐stabilizing carbamazepine in drinking water.” “The drinking water for Washington, D.C., and surrounding areas tested positive for six pharmaceuticals.” 7 The hazards of flushing…….. Sewage treatment systems are not equipped to remove medications from water. There is no routine testing for medications in drinking water Pharmaceuticals have been found in streams, rivers, lakes and in drinking water . The effects of these chemicals and mixtures on human health are unknown. Sewage treatment plants are not equipped for screening out or removing pharmaceuticals from our drinking water. Some medications also get into the water system after having been used by humans and excreted in the commode. 8 The ideal situation for medication disposal Pharmaceutical waste take back programs are the wave of the future. In the meantime, we need to find safer ways to dispose of unused medications AND We need to ensure that the agencies we work for have safe pharmaceutical disposal policies in place So what are we supposed to do? There are, unfortunately, no straight answers. Take‐back programs are beginning to be introduced into legislation. We need to have policies in place to make sure that medications are being thrown away to the right place at the right time. 9 Strategies for unused, non‐expired medications Check with the pharmacy that they were dispensed by to see if they will take them back for credit or proper disposal. You may be able to take advantage of community drug take‐back programs or other programs, such as household hazardous waste collection events, that collect drugs at a central location for proper disposal This only applies to non‐controlled substances. Opportunities for donating medications are few and far between. 10 When disposal is the only answer If the medication is expired, refused or contaminated you will need to dispose of it. Do NOT flush prescription drugs down the toilet or drain unless the label or accompanying patient information specifically instructs you to do so. 11 Safe medication disposal ‐ non controlled substances Take prescription drugs out of their original containers. Mix drugs with an undesirable substance, such as cat litter or used coffee grounds. Put the mixture into a disposable container with a lid, such as an empty margarine tub, or into a sealable bag. Unused or expired medicines that do not have flushing directions in the label can be safely disposed in the household trash by following this procedure. The procedure is recommended by national guidelines. 12 Continued Conceal or remove any personal information, including Rx number, on the empty containers by covering it with black permanent marker or duct tape, or by scratching it off. Place the sealed container with the mixture, and the empty drug containers, in the trash. http://www.smarxtdisposal.net/ 13 Disposal of controlled substances On October 12, 2010, President Obama signed the Secure and Responsible Drug Disposal Act. This bill amends the Controlled Substances Act to allow a user of a legal pharmaceutical to deliver the drugs to another person for disposal as long as the disposal is handled in a way that will keep the drugs from being diverted to another user. Controlled substances pose a hazard because they have a high potential of being abused. This law allows states and private entities to create programs to collect and safely dispose of unwanted prescription drugs. Previously, it was illegal to deliver a controlled substance to someone else for disposal. Now responsible parties can take back controlled substances. 14 Safe medication disposal ‐ controlled substances Because of this law there may now be programs that take back and dispose of controlled substances. The FDA still recommends that controlled medications be disposed of by flushing. Agencies should have policies to deal with the disposal of controlled substances. Often these policies involve disposal by the delegating nurse. The first national take‐back day was in September 2010. 121 tons of pills were collected from 3000 sites that day. Go to nationaltakebackday.com website, put in your zip code to see where and when you can bring back your excess drugs. Next national take back day is April 30th, 2011. The FDA recommendation about flushing medications is a guideline and not a policy. 15 This list from FDA tells you what unused or expired medicines you should flush down the sink or toilet. Actiq, oral transmucosal lozenge * Avinza, capsules (extended release) Daytrana, transdermal patch system Demerol, tablets * Demerol, oral solution * Diastat/Diastat AcuDial, rectal gel Dilaudid, tablets * Dilaudid, oral liquid * Dolophine Hydrochloride, tablets * Duragesic, patch (extended release) * Embeda, capsules (extended release) Exalgo, tablets (extended release) Fentora, tablets (buccal) Kadian, capsules (extended release) Methadone Hydrochloride, oral solution * Methadose, tablets * Morphine Sulfate, tablets (immediate release) * Morphine Sulfate, oral solution * MS Contin, tablets (extended release) * Onsolis, soluble film (buccal) Opana, tablets (immediate release) Opana ER, tablets (extended release) Oramorph SR, tablets (sustained release) Oxycontin, tablets (extended release) * Percocet, tablets * Percodan, tablets * Xyrem, oral solution To find this list, search for “FDA pharmaceutical disposal”. We still do not want these medications in the water system, but we definitely do not want them in our kids. It is therefore recommended that we flush them. 16 Compliance with Medication Technician Training When we are writing our agencies policies we need to make sure we are also complying with the medication technician training curriculum and the procedures set in place by the delegating nurse Procedures and clear guidelines are needed. 17 Model Programs in Maryland In Calvert County, the Calvert Alliance Against Substance Abuse has established a prescription drug disposal programs developed through a local public/private partnership have ensured the proper disposal of more than 700 pounds of prescription medications in just the first year of operation. Participating Calvert County pharmacies collected 600 pounds of unused prescription drugs in 2010 while county residents dropped off more than 146 pounds of medications at a Calvert County Sheriff’s Office drop box. 18 Take back partners Chesapeake Pharmacy of Chesapeake Beach and Calvert‐Arundel Pharmacy in Owings, are part of Maryland’s “Take‐Back” Program and accept the return of non‐narcotic prescriptions, over‐the‐counter drugs and supplements. The Calvert County Sheriff’s Office maintains a “24/7” pharmaceuticals drop box at its headquarters on Church Street in Prince Frederick that can be utilized at any time with no questions asked. County residents may also dispose of unused pharmaceuticals through one of the quarterly household hazardous waste disposal events sponsored by the Calvert County Division of Solid Waste. These one‐ day events give residents the opportunity to safely dispose of a wide variety of hazardous chemicals and substances, including unused medications. 19 Conclusions and Questions Flushing medication down the toilet is contributing to the pollution of our recreational and drinking water supply. Safer medication disposal techniques are available and effective . Watch for changes in your county as take back programs and waste management programs develop. Encourage your pharmacy to participate in efforts to reduce the unsafe disposal of medications ‐ Flushing is not the answer except for those controlled drugs. Procedures and policies for disposal of controlled drugs are needed. ‐ Trashbags with disposed of drugs go the landfill or are incinerated, so it is not perfect. ‐ Large facilities can have the pharmacies to take back unused medication. ‐ Should we get the drug manufacturers to be involved with disposal of drugs? 20