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DNA Replication Practice Worksheet
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True False Questions
Indicate True or False for the following Statements.
1. DNA polymerase can only build a strand in the 3’ to 5’ direction. ( True/False )
2. Meselson and Stahl grew E. coli for several generations in a medium with 15 N. ( True/False )
3. DNA replication produces two copies and each contains one of the original strands and one new strand. (
True/False )
4. After replication, each resulting DNA molecule is identical to the original DNA molecule, even if the molecule
is 200 million bases long. ( True/False )
Fill in the Blanks Questions
Fill in the answer blanks with correct answer.
5. __________ is an enzyme that builds a short RNA primer on the lagging strand during DNA replication.
Answer:
6. DNA is replicated through the __________ mechanism.
Answer:
7. __________ is the process in which a cell’s entire DNA is copied.
Answer:
8. DNA __________ is the enzyme that builds a new DNA strand during replication.
Answer:
9. During replication, the lagging strand is synthesized in short segments known as __________ fragments.
Answer:
Multiple Choice Questions
For each question, four alternative choices are given, of which only one is correct. You have to select the correct
alternative and mark it in the appropriate option.
10. __________ is the enzyme that can attach together, the DNA strands, with double strand breaks.
a.
b.
c.
d.
DNA helicase
Primase
DNA polymerase
DNA ligase
1
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Answer Keys
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
2
FALSE
TRUE
TRUE
TRUE
Primase
semi-conservative (or) semi conservative
DNA replication
polymerase
Okazaki
DNA ligase