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長庚大學生物醫學研究所 Chang Gung University, Graduate Institute of Biomedical Sciences 博士學位論文公開演講 Doctoral Oral Defence Seminar 演講者Speaker:林育存博士候選人PhD candidate 主持人Host:葉昭廷 教授 指導教授Advisor : 余兆松 教授 題 目 Title : Systemic exploration of dysregulated protein phosphorylation events in hepatocellular carcinoma by mass spectrometry-based approaches 時 間Time:民國106年3月30日 上午10:00 地 點Place:第一醫學大樓九樓B區會議室 ※※※ 歡迎參加 Welcome ※※※ 生物醫學研究所 Graduate Institute of BioMedical Sciences CURRICULUM VITAE Name : 林育存 (英文: Yu-Tsun Lin ) Education : 2007.9 ~ 2009.7 陽明大學醫學生物技術暨檢驗學系暨研究所 碩士 2003.9 ~ 2007.6 中國醫藥大學醫學檢驗生物技術學系 學士 Publication : 1. Chang KP, Lin SJ, Liu SC, Yi JS, Chien KY, Chi LM, Kao HK, Liang Y, Lin YT, Chang YS, Yu JS. (2015) Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma. Sci Rep. 2015 Jul 3;5:11689. 2. Chen H, Hsiao YC, Chiang SF, Wu CC, Lin YT, Liu H, Zhao H, Chen JS, Chang YS, Yu JS. (2016) Quantitative analysis of wild-type and V600E mutant BRAF proteins in colorectal carcinoma using immunoenrichment and targeted mass spectrometry. Anal Chim Acta. 2016 Aug 24;933:144-55. 3. Lin YT, Chien KY, Wu CC, Chang WY, Chu LJ, Chen MC, Yeh CT, Yu JS. (2017) Super-SILAC mix coupled with SIM/AIMS assays for targeted verification of phosphopeptides discovered in a large-scale phosphoproteome analysis of hepatocellular carcinoma. J Proteomics. 2017 Mar 22;157:40-51 Posters: 1. Lin YT, Yu JS. Identification of Dysregulated Kinase-Mediated Pathways in Hepatocellular Carcinoma by a Quantitative Phosphoproteome Approach. Graduate Institute of Biomedical Sciences, Chang Gung University, Tao-Yuan, Taiwan, June 2012. 2. Lin YT, Chien KY, Yeh CT, Yu JS. Identification of Dysregulated Kinase-Mediated Pathways in Hepatocellular Carcinoma by a Quantitative Phosphoproteome Approach. The 4th World Chinese Mass Spectrometry Conference, Tainan, Taiwan, June, 2012 3. Lin YT, Chien KY, Yeh CT, Yu JS. Identification of Dysregulated Kinase-Mediated Pathways in Hepatocellular Carcinoma by a Quantitative Phosphoproteome Approach. Taiwan Proteomics Society International Conference: Recent Advances in Translational Medicine, Taipei, Taiwan, May, 2013 4. Lin YT, Chien KY, Yeh CT, Yu JS. Mass Spectrometry-Based Discovery and Verification of Dysregulated Phosphoproteins in Human Liver Cancer. 第 14 屆 兩岸生物醫學討論會─蛋白質科學的研究, Shanghai, China, October, 2015. 5. Lin YT, Chien KY, Yeh CT, Yu JS. Super-SILAC mix Coupled with SIM/AIMS Assay for Targeted Verification of Phosphopeptides Discovered from Large Scale Phosphoproteome Analysis of Hepatocellular Carcinoma. (MP05-015) 15th Human Proteome Organization World Congress. Taipei, Taiwan, September, 2016. Oral presentation : Lin YT, Chien KY, Yeh CT, Yu JS. Mass Spectrometry-Based Discovery and Verification of Dysregulated Phosphoproteins in Human Liver Cancer 第 14 屆 兩岸 生物醫學討論會─蛋白質科學的研究, Shanghai, China, October, 2015.