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CURRICULUM VITAE Name: Kevin S. Choe, M.D., Ph.D. Office Address: University of Texas Southwestern Telephone #: (214) 645‐8525 Department of Radiation Oncology Fax #: (214) 645‐8526 5801 Forest Park Rd Dallas, TX 75390‐9183 Medical License/Certification: State of Texas Board Certification, American Board of Radiology Education: Massachusetts Institute of Technology, Cambridge, MA 1993‐1997, B.S. in Biology Albert Einstein College of Medicine, Bronx, NY 1997‐2005, M.D. and Ph.D. Postdoctoral Training: Internship Yale‐New Haven Hospital, Yale University School of Medicine 2005‐2006, Internal Medicine, New Haven, CT Residency University of Chicago Hospitals 2006‐2010, Radiation Oncology, Chicago, IL Externships Department of Oncology, Royal Marsden Hospital 11/2008, Clinical oncology elective, London, UK Seattle Prostate Institute and Puget Sound VA 5/2010, Low‐dose‐rate prostate brachytherapy, Seattle, WA Positions and Appointments: 8/2010‐present Assistant Professor, Department of Radiation Oncology University of Texas Southwestern, Dallas, TX 1/2011‐present Member, Simmons Cancer Center University of Texas Southwestern, Dallas, TX Scientific and Medical Societies: 2002‐present American Association for Cancer Research 2002‐present American Society for Therapeutic Radiology and Oncology 2006‐present Radiologic Society of North America Honors and Awards: 1993 Valedictorian, Lake Braddock Secondary School, Burke, Virginia 1994‐1996 Cancer Research Training Award, National Cancer Institute 1999‐2000 Fellowship Award, Howard Hughes Medical Institute 2006 Intern of the Year, Department of Medicine, Yale‐New Haven Hospital 2008 Chief Resident, Department of Radiation Oncology, University of Chicago 2009 Young Scientist/Investigator Award, American Society for Therapeutic Radiology and Oncology 2010 Fellowship Award, American Brachytherapy Society and Seattle Prostate Institute 2010 Roentgen Research Award, Radiological Society of North America Research and Education Foundation 2010 Scholarship, Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), University of California, San Francisco 2011 Brain Tumor Research Award, American Brain Tumor Association 2011 Distinguished Researcher Award, President's Research Council, University of Texas Southwestern Service to Professional Societies and Journals: 2009‐present Reviewer, Cancer 2010‐present Reviewer, American Journal of Clinical Oncology Committee Assignment: 2001‐2002 5‐year Reunion Committee, MIT 2
2008‐2009 Selection Committee for Radiation Oncology Residency, University of Chicago 2010‐present Selection Committee for Radiation Oncology Residency, University of Texas Southwestern 2011‐present Faculty Senate, University of Texas Southwestern Languages: Spoken: Studied: Publications: English, Korean Latin 1. Bai R, Choe K, Ewell JB, Nguyen NY, Hamel E. Direct photoaffinity labeling of cysteine‐295 of alpha‐tubulin by guanosine 5'‐triphosphate bound in the nonexchangeable site. J Biol Chem. 1998 Apr 17; 273(16):9894‐9897. 2. Peter DG, Hoover RR, Gerlach MJ, Koh EY, Zhang H, Choe K, Kirschmeier P, Bishop WR, Daley GQ. Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL‐
induced murine leukemia and primary cells from patients with chronic myeloid leukemia. Blood. 2001 Mar 1; 97(5): 1404‐1412. 3. Choe KS, Radparvar F, Matushansky I, Rekhtman N, Han X, Skoultchi AI. Reversal of tumorigenicity and the block to differentiation in erythroleukemia cells by GATA‐1. Cancer Res. 2003 Oct 1; 63(19): 6363‐6369. 4. Rekhtman N, Choe KS, Matushansky I, Murray S, Stopka T, Skoultchi AI. PU.1 and pRB interact and cooperate to repress GATA‐1 and block erythroid differentiation. Mol Cell Biol. 2003 Nov; 23(21): 7460‐7474. 5. Choe KS, Salama JK. Recent Advances in radiation therapy for tumors involving the mediastinum. Thorac Surg Clin. 2009 Feb; 19(1):133‐141. 6. Choe KS, Ujhelly O, Wontakal SN, Skoultchi AI. PU.1 directly regulates CDK6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells. J Biol Chem. 2010 Jan; 285(5): 3044‐3052. 7. Choe KS, Jani AB, Liauw SL. External beam radiotherapy for prostate cancer patients on anticoagulation: How significant is the bleeding toxicity? Int J Radiat Oncol Biol Phys. 2010 Mar; 76(3): 755‐760. 8. Choe KS, Correa D, Jani AB, Liauw SL. Use of anticoagulation therapy improves biochemical control of localized prostate cancer treated with radiotherapy. Cancer. 2010 April; 116(7): 1820‐1826. 3
9. Choe KS, Liauw SL. Radiotherapeutic strategies in the management of low‐risk prostate cancer. Scientific World Journal. 2010 Sept; 1854‐1869. 10. Choe KS, Salama JK, Stenson KM, Blair EA, Witt ME, Cohen EEW, Haraf DJ, Vokes EE. Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer. Radiother Oncol. 2010 Nov; 97(2): 318‐321. 11. Choe KS, Haraf DJ, Solanki A, Cohen EE, Seiwert TY, Stenson KM, Blair EA, Portugal L, Villaflor VM, Witt ME, Vokes EE, Salama JK. Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation. Cancer. 2011 Oct 15; 117(20): 4671‐4678. 12. Kim DN, Nam TK, Choe KS, Choy H. Personalized combined modality therapy for locally advanced non‐small cell lung cancer. Cancer Res Treat. 2012 Jun; 44(2): 74‐84. 13. Chun, SG, Choe KS, Iyengar P, Yordy JS, Timmerman RD. Isolated central nervous system progression on Crizotinib: An Achilles heel of non‐small cell lung cancer with EML4‐ALK translocation? Cancer Biol Ther. 2012 Sep; 17(14) 14. Choe KS, Cowan JE, Chan JM, Carroll PR, D’Amico AV, Liauw SL. Aspirin use and the risk of prostate cancer mortality in men treated with prostatectomy or radiotherapy. J Clin Oncol. 2012 Oct 1; 30(28): 3540‐3544. Abstracts: 1. Bai R, Choe K, Hamel E. Localization of the nonexchangeable GTP binding site on tubulin by direct photoaffinity labeling. Poster, American Association for Cancer Research (AACR), Annual Meeting, San Diego, CA, April 1997. 2. Choe KS, Skoultchi, AI. Role of hematopoietic transcription factors, PU.1 and GATA‐1 in erythroleukemogenesis. Oral Presentation, Howard Hughes Medical Institute, Chevy Chase, MD, May 2000. 3. Choe KS, Matushansky I, Skoultchi AI. Linking proliferation and the block to differentiation in leukemia: A potential regulatory loop between PU.1 and CDK6. Poster, ASTRO Annual Meeting, New Orleans, LA, Oct 2002. 4. Choe KS, Matushansky I, Rekhtman, M, Skoultchi, AI. Linking proliferation and the block to differentiation in leukemia: A potential regulatory loop between CDK6 and PU.1. Poster, American Association for Cancer Research (AACR), Annual Meeting, Washington, DC, July 2003. 5. Devisetty K, Jani AB, Choe KS, Liauw SL. Should prior TURP Influence the decision to treat prostate cancer with external beam radiation therapy? Poster, ASTRO Annual Meeting, Los Angeles, CA, Oct 2007. 6. Choe KS, Jani AB, Liauw SL. Should radiation therapy be modified for patients with prostate cancer on anticoagulants? Poster, ASTRO Annual Meeting, Los Angeles, CA, Oct 2007. 4
7. Solanki A, Stenson K, Haraf DJ, Choe KS, Cohen E, Seiwert T, Blair E, Vokes E, Salama JK. Pathologic predictors for outcome in recurrent and second primary head and neck cancer patients undergoing surgery followed by concurrent chemo‐reirradiation. Poster, ASTRO Annual Meeting, Boston, MA, Sept 2008. 8. Choe KS, Solanki A, Haraf DJ, Cohen EE, Seiwert T, Stenson K, Blair E, Witt ME, Dekker A, Salama JK. Previous chemoradiotherapy predicts for worse survival in patients undergoing chemo‐reirradiation for recurrent and second primary head and neck cancer. Poster, ASTRO Annual Meeting, Boston, MA, Sept 2008. 9. Choe KS, Correa D, Jani AB, Liauw SL. Use of anticoagulants improves biochemical control of localized prostate cancer treated with radiotherapy. Poster, ASTRO Annual Meeting, Chicago, IL, Oct 2009. 10. Choe KS, Salama JK, Stenson KM, Blair E, Witt ME, Cohen EE, Haraf DJ, Vokes EE. Postoperative chemotherapy prior to adjuvant concurrent chemoradiotherapy improves local and distant control in locoregionally advanced head and neck cancer. Poster, Multidisciplinary Head and Neck Cancer Symposium, Chandler, AZ, Feb 2010. 11. Malik R, Pederson AW, Choe KS, Witt ME, Salama JK, Cohen EE, Blair EA, Stenson KM, Vokes EE, Haraf DJ. Impact of induction chemotherapy on treatment outcomes in locoregionally advanced head and neck carcinoma patients treated with concurrent chemotherapy and hyperfractionated radiotherapy. Poster, ASTRO Annual Meeting, San Diego, CA, Oct 2010. 12. Choe KS, Cowan JE, Carroll PR, D’Amico AV, Liauw SL. Aspirin use and the risk of prostate cancer death in men treated with prostatectomy or radiotherapy: results from the CaPSURE database. Oral Presentation, ASTRO Annual Meeting, San Diego, CA, Oct 2010. 13. Yoon T, Loughlin D, Yu S, Desai B, Choe KS, Minn AJ. Functional characterization of a DNA damage response network in glioblastoma associated with long‐term patient survival. Poster, American Association for Cancer Research (AACR) Annual Meeting, Chicago, IL, March 2012. Books and Chapters: 1. Nedzi LA, Choe KS, Ramirez E, Pompos A. “Central Nervous System”. In: Treatment Planning in Radiation Oncology, Third Edition. Edited by Faiz M. Khan, Bruce J. Gerbi, and Kathryn E. Dusenbery., Lippincott Williams & Wilkins, Philadelphia. 2011. 2. Choe KS, Salama JK, Cohen RR. “Concurrent Chemotherapy and Reirradiation for Recurrent Head and Neck Cancer”. In: Management of Head and Neck Recurrence. Edited by Hisham Mehanna nd Kian K. Ang., Thieme Publishing Group, Stuttgart. 2012. 5