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(DBIO 01NR) ASSIGNMENT - 1, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper I — PRINCIPLES OF CELL AND MOLECULAR BIOLOGY AND BIOINFORMATICS Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Describe the Chloroplast structure and its functions 2) Write an account on Cell theory 3) Describe the Meoisis with well labelled diagrams 4) Enumerate Genome structure and its Organisation 5) Explain DNA as Genetic material _______ (DBIO 01) ASSIGNMENT - 2, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper I — PRINCIPLES OF CELL AND MOLECULAR BIOLOGY AND BIOINFORMATICS Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Describe Genetic code and its applications 2) Describe the Various types of Mutations 3) Explain the mechanisms of DNA repair 4) Write an account on the scope of Bioinformatics in Molecular biology 5) Describe the applications of Drug discovery _______ (DBIO 02NR) ASSIGNMENT - 1, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - II : NUMERICAL METHODS, OPTIMIZATION TECHNIQUES AND COMPUTER PROGRAMMING Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Explain the biological models and their phenomenon in inherent parallelism. 2) Explain parallel versus sequential computing. 3) Describe the operating systems and their Uses. 4) Write an account on generation of computers. 5) Describe optimization and explain any one of its technique. _______ (DBIO 02NR) ASSIGNMENT - 2, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - II : NUMERICAL METHODS, OPTIMIZATION TECHNIQUES AND COMPUTER PROGRAMMING Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Describe the errors involved in the construction of mathematical models. 2) Describe the randomized minimization techniques. 3) Explain the functions of minimization and maximization. 4) Describe the salient features in designing of a web page. 5) Explain the programming with HTML and its applications. _______ (DBIO 03NR) ASSIGNMENT - 1, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - III : DATABASE MANAGEMENT AND BIOLOGICAL DATA BANKS MOLECULAR DESIGNING Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Explain the information processing challenges in biology. 2) Describe biological data banks. 3) Explain Genomic data banks. 4) Enumerate the microbial data banks. 5) Describe the NCBI data model. _______ (DBIO 03NR) ASSIGNMENT - 2, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - III : DATABASE MANAGEMENT AND BIOLOGICAL DATA BANKS MOLECULAR DESIGNING Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Explain the PDB data model. 2) Describe the primary structure of proteins with suitable examples. 3) Describe the tertiary structure of DNA. 4) Describe the structural prediction of biopolymers. 5) Write an account on phylogenetic analysis and its importance. _______ (DBIO 04NR) ASSIGNMENT - 1, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - IV : GENOMIC AND PROTEOMICS AND SEQUENCING ANALYSIS Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Describe the structure and functions of Organellar genomes. 2) Write an account on Viral genomes. 3) Describe the regulation of gene expression. 4) Write an account on genome projects and their uses. 5) Describe the Protein purification and degradation. _______ (DBIO 04NR) ASSIGNMENT - 2, MAY-2014. P.G. DIPLOMA IN BIOINFORMATICS Paper - IV : GENOMIC AND PROTEOMICS AND SEQUENCING ANALYSIS Maximum : 20 MARKS Answer ALL questions. All questions carry equal marks. 1) Explain the post transcriptional modifications. 2) Describe the methods of drug design and delivery process. 3) Describe the predictive methods using DNA sequences. 4) Describe PCR and its applications in molecular biology. 5) Write an account on Bioethics. _______