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No. of Printed Pages : 8 CHE-09 BACHELOR OF SCIENCE (B.Sc.) Term-End Examination June, 2016 00147 CHEMISTRY CHE-09 : BIOCHEMISTRY Maximum Marks : 50 Time : 2 hours Note : Answer any five questions. All questions carry equal marks. 1. (a) Fill in the blanks in the following : (i) 3 Fatty acid oxidation takes place in (ii) Glycolysis of each glucose residue of glycogen leads to a net generation of molecules of ATP. is major the (iii) immunoglobulin in normal human serum. (b) Give any four differences between prokaryotes and eukaryotes. 4 (c) What are isoenzymes ? Explain giving one example. 3 CHE-09 1 P.T.O. 2. (a) Write one scientific contribution of any four of the following : (i) Hershey and Chase (ii) Northrop and Kunitz (iii) S.J. Singer and G.L. Nicolson (iv) Melvin Kelvin (v) Watson and Crick (b) Give one difference (structure and function) between any three of the following : 3. (i) Glycogen and Cellulose (ii) Lipoprotein and Prostaglandin (iii) a-helix and [3-pleated sheet (iv) Deoxyribonucleic acid and Ribonucleic acid (a) 'What is metastasis ? Why is it life threatening ? (b) (c) (d) CHE-09 4 6 2 Why is ATP called the energy currency of a living cell ? 3 What are the forces stabilising the tertiary structure of proteins ? 2 How is pyruvate metabolised under different physiological conditions ? 3 2 4. (a) Name the coenzyme form of vitamin B5. Write the structure of this coenzyme. What is genetic code ? Give any three salient features of the genetic code. 4 Explain the mode of action of streptomycin and puromycin. 3 (a) Write the structures of any four of the following : 4 (b) (c) 5. (b) (c) 6. 3 (i) Adenosine (ii) Sucrose (iii) Glutamine (iv) Phosphatidylcholine (v) Nicotinic acid (vi) Acetyl CoA Name any four factors that modify the immune response and describe in brief any one of these. 4 Define melting point of DNA. What are the factors affecting it ? 2 (a) Humans can convert glucose into fatty acids but cannot convert fatty acids into glucose. Explain why. 3 (b) (c) CHE-09 What is substrate level phosphorylation ? Give an example. 3 Give the names of any two fat soluble and water soluble vitamins and one disease each caused by their deficiency. 4 3 P.T.O. 7. (a) Explain the term enzyme immobilization. Write any one method used for immobilization of enzymes. (b) Describe the similarities between DNA replication and RNA transcription. (c) 4 3 Write the role of thylakoid membrane and stroma in the photosynthetic process. What are the products formed in the light reactions of photosynthesis ? CHE-09 4 3 T11.7w.t.-o9 (*LT; Tft.) Trgta trftwr V', 2016 firoT4 tilich 117714 :*47TIT417 317WRIT 3* : 50 0401 : 2 E74 adz : 1. fk4fi w RFT JR? e07 Alf* A ikw *441-1 . () (i) ATIT 3T4:11 (ii) loiqen : 3 A d‘ozitoi tI ar4fOrz * • Ta 014eniomi drif apjaff , ATP t -grgstr (iii) 3* f14114 / USlt • *PT 04016,51.1 err /Lk-We -4t A t R 3 4 lcil4l I ? til-RAIPI WU " dqwui ct)t 3 I CHE-09 Apt 5 P.T.O. 14 *7.41 2. (T) 'PHiCiRgo wrf. twf* zhTgrq foRg7 : 4 1-1MTT (i) tt11TEF MIT Tr-4 -7 (ii) M1T1. cr . 'Pct) (iii) (iv) '14fq (v) ale,tm MTT PHRIRSCI fpm 14 aiffK 6 WalT Ncbiti TWO 'FP? *1147 : (i) 1 (1W;t:A41•1 MTT4Ta M-1T I*14(,1141 (ii) 41 MIT (3-chrolfZio a- (iv) tattwftti aTgF e.14. 3. 7z11 (1g) tiki) 4fle. a.T11- TAT &I*611-eketc-114) TEIT ? miumott 2 ? ATP Irkff ch)Dicni 41' crti) 4)1 3 ? (Tr) (V) A* tr Itzr* TATfir 41.1-4-1-4 old few. 41(1k1;neno-i4h 3414'11 I CHE-09 -P,Tra741 ? 6 2 ? trro---dz rchi 3 4. vtr. 'Rd* B5 t1 fA17 I 3 *4111 ?ARI ,711§14 ? aTrOftm cns aTFORm ails err alai q;li 4ri idDit.e.Mitrr 61014 m:fr 0441(9en *If*I iir 5. 4'i 4 ci *1 %-if W7f 3 titbitcr PAR : - 4 (i) ta*RTR(ii) Vt) (iii) Tiftq (iv) it ei§ rig) (v) PchlaPet, aTru (vi) ted-F CoA fcl t 3-1-1WzIT 4 TIr WR~ trMfrc (1 W4 al -CK We rr1-4 14.4. -qw *Oct > au`-1 *04R 4 DNA 71-Ttf d. crairl cbRen 6. *IP47..t.)) ? kichoi -4'EfT 3.11 11 iiRago TT414 iT*- 1- lifkago Tef t "7 .4m aTI:11 t I eqtt9qi *if4R, TO I ? 7-* f*-4P-TR art lilitAtARichtui err 1:1-164 3 3 3qWul tr4R r mrr 31F1- -14 47 dcWul tP* chltui -04 aKs) trt?AR I aur CHE-09 2 7 * ail t-t 4=t 4 P.T.O. 7. trq *1- oeittatil 41-PA7 Pgarfl cntui 14.441.hvii f4N- fAi7 mgm q - crw I 4 (Iii) DNA 313T% Wall RNA alZfq "45M *'ri* I 3 (IT) mctoi-TiWt Nst)+-1 14 2TRAWRMf rc'ffAT tfrUT 1:bag) CHE-09 iftwr foR§R alfiftErrall -q:ETT 8 I mctoi-TiEruT 3Ccl iq 61-1 ? 3 4,000