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4.1 What is a Cell? Each cell has a plasma membrane, cytoplasm, and a nucleus (in eukaryotic cells) or a nucleoid (in prokaryotic cells) Cell Structure and Function Chapter 4 cytoplasm DNA in nucleus cytoplasm DNA plasma membrane plasma membrane a Bacterial cell (prokaryotic) b Plant cell (eukaryotic) Fig. 4.3, p. 52 Fig. 4.3, p. 52 1 Components of Cell Membranes cytoplasm Lipid bilayer DNA in nucleus plasma membrane c Animal cell (eukaryotic) Fig. 4.3, p. 52 Key Concepts: Cell Size and Shape WHAT ALL CELLS HAVE IN COMMON Surface-to-volume ratio limits cell size Each cell has a plasma membrane, a boundary between its interior and the outside environment The interior consists of cytoplasm and an innermost region of DNA 2 4.2 How Do We See Cells? Relative Sizes Three key points of the cell theory: • All organisms consist of one or more cells • The cell is the smallest unit that retains the capacity for life • A cell arises from the growth and division of another cell 4.3 Membrane Structure and Function Common Membrane Proteins Each cell membrane is a boundary (lipid bilayer) that controls the flow of substances across it Fluid mosaic model • Membrane is composed of phospholipids, sterols, proteins, and other components • Phospholipids drift within the bilayer 3 4.4 Introducing Prokaryotic Cells Prokaryote Structure Cell wall Bacteria and archaeans • Surrounds plasma membrane • The simplest cells • The groups with greatest metabolic diversity Flagella • Used for motion Biofilms Pili • Shared living arrangements of prokaryotes • Protein filaments used for attachment • “Sex” pilus transfers genetic material 4.6 Introducing Eukaryotic Cells cytoplasm, with ribosomes Most prokaryotic cells have a cell wall outside the plasma membrane, and many have a thick, jellylike capsule around the wall. Start with a nucleus and other organelles • Carry out specialized functions inside a cell bacterial flagellum DNA in cell plasma pilus capsule wall membrane nucleoid Fig. 4.11, p. 58 4 Components of Eukaryotic Cells 4.7 Components of The Nucleus Nucleus separates DNA from cytoplasm • Chromatin (all chromosomal DNA with proteins) • Chromosomes (condensed) Nucleolus assembles ribosome subunits Nuclear envelope encloses nucleoplasm • Pores, receptors, transport proteins Nucleus and Nuclear Envelope Nucleus and Nuclear Envelope 5 Nucleus and Nuclear Envelope 4.8 The Endomembrane System Endoplasmic reticulum (ER) • An extension of the nuclear envelope • RER modifies new polypeptide chains • SER makes lipids; other metabolic functions Golgi bodies • Further modify polypeptides • Assemble lipids The Endomembrane System Endomembrane System Vesicles • Endocytic and exocytic: Transport or store polypeptides and lipids • Peroxisomes: Digest fatty acids and amino acids; break down toxins and metabolic by-products • Lysosomes: Intracellular digestion (animals) • Central vacuole: Storage; fluid pressure (plants) 6 Endomembrane System Endomembrane System 4.9 Mitochondria and Chloroplasts Mitochondria and Chloroplasts Mitochondria • Break down organic compounds by aerobic respiration (oxygen-requiring) • Produce ATP Chloroplasts • Produce sugars by photosynthesis 7 Plant Cuticle free surface of epithelial tissue Protective surface secretion, limits water loss different kinds of tight junctions gap junction basement membrane (extracellular matrix) 4.12 The Dynamic Cytoskeleton adhering junction Fig. 4.23, p. 67 Components of the Cytoskeleton Components of the cytoskeleton • Microtubules • Microfilaments • Intermediate filaments (in most) 8 Cytoskeleton Function Flagellum and Pseudopods Organizes and moves cell parts Reinforces cell shape Interactions between motor proteins and microtubules in cilia, flagella, and pseudopods can move the whole cell 9