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Ministry of Higher Education
Salman Bin Abdulaziz University
College of Applied Medical Sciences
Department of Medical Lab Sciences
‫وزارة التعليم العالي‬
‫جامعة سلمان بن عبد العزيز‬
‫كلية العلوم الطبية التطبيقية‬
‫قسم علوم المختبرات الطبية‬
1st Midterm Examination of Basic Biochemistry (MLAB 242) – 1434/1435 AH.
Exam Period: 1 Hour
Full Marks= 15
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Student Name:
Student's University No:
Make sure that your name is on every page. Read each question carefully before answering,
points are indicated by the question within brackets [ ].
Question-1 [ 4 points ] Choose true (T) or false (F) to these statements:
( F ) An ionic bond is a bond that is formed when two atoms share electrons.
( T ) Monomers of nucleic acids are called nucleotides.
( F ) Pyrimidine bases are Adenine & Guanine.
( F ) Sucrose is a disaccharide consists of Glucose and Fructose linked by ester linkage.
( F ) The formation of a peptide bond between two amino acids is an example of a hydrolysis
reaction.
( F ) Acidic negatively charged amino acids are Arginine, Lysine, and Histidine.
( F ) Fibrous proteins are globular in shape, and compactly folded and coiled, they are soluble
in water and the axial ratio is 3-4.
( T ) Protein primary structure is the linear sequence of amino acids that make up a protein.
Question-2 [ 4 points ] Fill in the missing words in the following statements:
- The structural unit of living systems is …cell.....
- Carbohydrates are made from monomer called …..monosaccharide.....
- When amino acids combine, they form a special bond called a ….peptide bond.... and become
a polypeptide, or protein.
- Water is a …polar.... molecule, it is formed when two atoms of hydrogen bond covalently with
an atom of oxygen.
- Compounds that dissolve easily in water are called …hydrophilic... compounds.
- The forces that hold the non polar regions of the molecules together are called ..hydrophobic..
interactions.
- In the blood, the pH value normally ranges only between …7.35 and 7.45...
- Acids are those substances that can donate …hydrogen... ions.
Student Name:
Student's University No:
Question-3 [ 2 points ] Compare between DNA & RNA with regard to their location, structure,
containing sugar, and function in eukaryotic cell.
Molecule
DNA
RNA
Location
In the cell
Throughout
the cell
Structure
Containing sugar
Double strand Deoxyribose
Single strand
Ribose
Function
Stores genetic information
Translates genetic information
into amino acids sequence of
protein
Question-4 [ 2 points ] Write down four (4) important biological functions of proteins.
1234-
Carry oxygen in the blood
Provide support
Act as a catalyst
Regulate cell activities
Question-5 [ 3 points ] Draw the general chemical structure of amino acid, Zwitter ion, and
show how peptide bond is formed between two amino acids.
General Structure
Zwitter Ion