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CURICULUM VITAE DATE: February 2017 NAME: MARCOS PAULO FERREIRA BOTELHO, M.D. PRESENT TITLE: Assistant Professor of Radiology ADDRESS: The University of Texas McGovern Medical School at Houston Department Diagnostic and Interventional Imaging 6431 Fannin Street, MSB 2.130B Houston, Texas 77030 CITIZENSHIP: Brazil USA Permanent Residency pending GRADUATE EDUCATION: Medical Degree, 1999 – 2004 Santa Casa of Sao Paulo, Medical School Sao Paulo, Brazil CLERKSHIP: Anatomic Radiology Clerkship, 2003 Mount Sinai School of Medicine New York, New York POSTGRADUATE TRAINING: TRANSITIONAL YEAR Escola Preparatória de Cadetes do Exército, 2005 - 2006 Campinas, Brazil RESIDENCY: Irmandade Santa Casa de Misericordia de São Paulo, 2006- 2009 São Paulo, Brazil CONTINUING EDUCATION: Harvard School of Medicine, 2009 - 2009 “Principles and Practice of Clinical Research”, Clinical Trials 2009, Live webinars from Scholars in Clinical Science Program & Department of Continuing Education FELLOWSHIPS: Oncologic Imaging and Non-Vascular Interventional Radiology, 2009 – 2010 Universidade de São Paulo Faculdade de Medicina – São Paulo State Cancer Institute, São Paulo, Brazil CT Research Fellowship, 2012 – 2013 Siemens Educational Grant Support Department of Radiology McGaw Medical Center - Northwestern University Chicago, Illinois, USA Cardiovascular Imaging Fellowship, 2013 – 2014 Department of Radiology Northwestern Memorial Hospital McGaw Medical Center - Northwestern University Chicago, Illinois Pediatric Radiology Fellowship, 2014 – 2015 Lurie Children’s Hospital McGaw Medical Center - Northwestern University Chicago, Illinois MRI Fellowship, 2015 – 2016 Department of Radiology Northwestern Memorial Hospital McGaw Medical Center - Northwestern University Chicago, Illinois In collaboration with North Shore University Health System Evanston, Illinois PROFESSIONAL EXPERIENCE: Hospital do Coração/Hospital Alemão Oswaldo Cruz, 2008 – 2010 São Paulo, Brazil Hospital Santa Julia, 2010 - 2011 Manaus, Brazil Prodimagem Clinic, 2011 – 2012 Manaus, Brazil CEMED Imagem, 2010 – 2012 Manaus, Brazil Federal University of Amazonas (UFAM) - Hospital Getulio Vargas, 2011 – 2012 Manaus, Brazil ACADEMIC APPOINTMENTS: Assistant Professor of Radiology, August 2016 – Present Pediatric and Cadiovascular Radiology Department of Diagnostic and Interventional Imaging, McGovern Medical School The University of Texas Health Science Center at Houston HOSPITAL APPOINTMENTS: Staff Physician, Radiology, August 2016 - Present Lyndon B. Johnson Hospital – Houston / TX Memorial Hermann Hospital – Texas Medical Center - Houston, Texas LICENSURE: Illinois – Full license: 036139319 Texas Faculty Permit: 45464 CERTIFICATION: American Board of Radiology: Certified in Diagnostic Radiology Brazilian College of Radiology: Certified in Radiology and Diagnostic Imaging Society for Cardiovascular Magnetic Resonance: Certified Level III reader PROFESSIONAL ORGANIZATIONS: NATIONAL: Society for Pediatric Radiology, 2014 American Roentgen Ray Society, 2012 Radiological Society of North America, 2006 North American Society of Cardiovascular Imaging, 2013 Society for Cardiovascular Magnetic Resonance, 2013 INTERNATIONAL SOCIETIES: European Society of Radiology, 2012 Brazilian College of Radiology, 2009 HONORS AND AWARDS: Education Exhibits at RSNA, 2012 Certificates of Merit: - State of the Art Radiation Dose Reduction in MDCT - Understanding Terminology and Imaging Endpoints in Oncological Trials: Closing the Gap in Communication between Oncologists and Abdominal Radiologists Scientific Abstract at Society of Abdominal Radiology, 2013 Roscoe E. Miller - Best GI Paper Presentation Award - Does 90Y-Radioembolization of Colon Cancer Liver Metastases in One Lobe Alter the Growth Kinetics of Contralateral Untreated Lesions? Scientific abstracts at NASCI 2014 and SMRA, 2015 - Cardiac MR derived myocardial global strain in biopsy-proven non-ischemic cardiomyopathies: A Feasibility study AHA CVRI Young Investigator Award finalist at NASCI, 2014 Travel Award recipient Society for MRA, 2015 Best image contest at SCMR 2016 – 3rd place Image: “Coronary Dream” PAST GRANT SUPPORT: Siemens AG Educational Grant Support – 2012/2013 - $40000 PUBLICATIONS: 1. SOUZA, F.; PEDRO, J.; VIEIRA, J.; BOTELHO, MPF; MATHIAS, L. The validity of the Electrocardiogram accomplishment in the elderly surgical patient preoperative evaluation. Rev Bras Anestesiol, vol.55, Fev 2005, No.1, p.59-71. 2. MATHIAS, L.; BOTELHO, MPF; OLIVEIRA, L.; et al. Prevalence of signs/symptoms suggestive of latex sensitization in health care workers. Rev Bras Anestesiol, Vol. 56 N°2, Mar- Apr, 2006, p.137–146 3. GONZALEZ-GUINDALINI, F.; BOTELHO, M.; HARMATH, C.; SANDRASEGARAN, K.; MILLER, F.; SALEM, R.; YAGHMAI, V. Assessment of Liver Tumor Response to Therapy: Role of Quantitative Imaging. Radiographics, Oct/2013 4. GONZALEZ-GUINDALINI, F.; BOTELHO, M.; TORE, H.; AHN, R.; GORDON, L.; YAGHMAI, V. MDCT of Chest, Abdomen and Pelvis Using Automated Attenuation-based Tube Voltage Selection in Combination with Iterative Reconstruction: An Intra-Patient Study of Radiation Dose and Image Quality. AJR, Nov/2013 5. BOTELHO, M.; AGRAWAL, R.; GONZALEZ-GUINDALINI, F.; HART, E.; PATEL, S..; TORE, H.; YAGHMAI, V. Effect of radiation dose and iterative reconstruction on lung lesion conspicuity at MDCT: Does one size fit all? European Journal of Radiology, Nov/2013 6. TORE, H.; ENTEZARI, P.; CHALIAN H.; GONZALEZ-GUINDALINI, F.; BOTELHO, M.; YAGHMAI, V. Optimization of Reduced Dose MDCT of Thoracic Aorta Using Iterative Reconstruction. J Compute Assist Tomogr, Jan-Feb 2014 7. BOTELHO, M.; SEYAL, A.; GONZALEZ-GUINDALINI, F.; HARMATH, C.; GALIZIA, M. YAGHMAI, V. The combined effect of MDCT tube voltage, tube current and image reconstruction algorithm on the detection of pneumothorax after intervention. J Compute Assist Tomogr EPub ahead of print/ March 27, 2014 8. LIBERMAN, A.; DARUWALLA, V.; COLLINS, J.; MAAS, M.; BOTELHO, M.; BOU AYACHE, J.; CARR, J.; RUFF, I.; BERNSTEIN, R.; ALBERTS, M.; PRABHAKARAN, S. Yield of Pelvic Magnetic Resonance Venography in Cryptogenic Stroke with Patent Foramen Ovale – Stroke – AHA - EPub ahead of print – June 17, 2014 9. EDELMAN, R.; GIRI, S.; PURSNANI, A.; BOTELHO, M.; LI, W.; KOKZTOGLOU, I. BreathHold Imaging of the Coronary Arteries using Quiescent-Interval Slice-Selective (QISS) Magnetic Resonance Angiography: Evaluation at 1.5 Tesla and 3 Tesla – (2015) 17:101 Journal of Cardiovascular Magnetic Resonance 10. ALLEN, B; CARR, M; BOTELHO, MPF.; RAHSEPAR, A; MARKL, M; ZENGE, M; SCHMIDT, M; NADAR, M; SPOTTISWOOD, B; COLLINS, J; CARR, J - Highly accelerated cardiac MRI using iterative SENSE reconstruction- initial clinical experience - Int J Cardiovasc Imaging - Feb 2016 11. BOTELHO, MPF; KOKTZOGLOU, I.; COLLINS, JD; GIRI, S; CARR, JC; GUPTA, N; EDELMAN, RR - MR Imaging of Ilio-Femoral Peripheral Vascular Calcifications using Proton Density- Weighted, In-Phase 3D Stack-of-Stars Gradient-Echo – Mag Res Med –June 2016 12. BRIAN TRINH, IRAM DUBIN, OZAIR RAHMAN, MARCOS P FERREIRA BOTELHO, NICHOLAS NARO, JAMES C CARR, JEREMY D COLLINS, ALEX J BARKER, Aortic Volumetry at Contrast-enhanced MR Angiography: Feasibility as a Sensitive Method for Monitoring Bicuspid Aortic Valve Aortopathy – Academic Radiology – Jan 2017 13. EDELMAN, RR; BOTELHO, MPF; PURSNANI, A; GIRI, S; KOKTZOGLOU, I - Improved Dark Blood Imaging of the Heart using Radial Balanced Steady-State Free Precession – JCMR – Jan/2017 14 - AMIR ALI RAHSEPAR, MD, AHMADREZA GHASEMIESFE, MD, RAHUL N SAWLANI, MD, MARCOS P FERREIRA BOTELHO, MD, AJIT S PAINTAL, MD, YANKI TUMER, MD, S. CHRIS MALAISRIE, MD, BENJAMIN H FREED, MD, JEREMY D. COLLINS, MD, JAMES C. CARR, MD - A Papillary Fibroelastoma involving aortic and pulmonary valves: findings on multimodality imaging – The Annals of Thoracic Surgery – Jan/2017 MANUSCRIPT UNDER REVISION: 15 - Amir Ali Rahsepar, Haris Saybasili, Ahmadreza Ghasemiesfe, Marcos P. Ferreira Botelho, Ann Ragin, Michael Markl, Bruce Spottiswoode, Jeremy D. Collins, James C. Carr. - Motion Corrected Real Time Cine MRI of the Heart: Initial Clinical Experience ABSTRACTS: 1. Scientific initiation project with financial support from the Brazilian government (CNPq) ($5000) “Prevalence of Latex Sensitive Healthcare Professionals: Comparative Study between the different levels and duration of exposure” São Paulo, 2003 2. Monitoring Radiation Dose from MDCT Examinations of Patients Referred to a Large Tertiary Center Scientific Abstract Presentation at R.S.N.A., 2012 3. Association of automated kVp selection and Sinogram affirmed iterative reconstruction in CT Angiography for renal donors - Scientific Abstract Presentation at E.C.R., 2013 4. Automated kVp Selection and Sinogram Affirmed Iterative Reconstruction to Reduce CT Dose in Oncological Patients with Abdominal cancer undergoing surveillance Scientific Abstract Presentation at A.R.R.S., 2013 5. Using volumetric attenuation change at one month to predict future response based on EASL criteria at three months in Hepatocellular Carcinoma (HCC) treated with 90Y radioembolization Scientific Abstract Presentation at A.R.R.S. 2013 6. Effect of acquisition parameters and reconstruction algorithm on lesion conspicuity in low dose MDCT of the thorax Scientific Abstract Presentation at E.C.R. 2013 7. Semi-automated Volume try of Pleural Effusion Scientific Abstract Presentation at E.C.R., 2013 with special report at AuntMinnie.com 8. Does 90Y-Radioembolization of Colon Cancer Liver Metastases in One Lobe Alter the Growth Kinetics of Contralateral Untreated Lesions? Roscoe E. Miller Best GI Paper Presentation Award SAR 2013 9. Effect of Using Automated kVp Selection and Sinogram Affirmed Iterative Reconstruction in Reducing Patient Dose Exposure in CT Enterography Scientific Abstract Presentation at S.A.R. and A.R.R.S. 2013 10. Attenuation based automated kVp selection with sinogram affirmed iterative reconstruction To reduce radiation dose in emergent CT scans of abdomen and pelvis: an intra-patient comparison Scientific Abstract Presentation at S.A.R. and A.R.R.S. 2013 11. Detecting Pneumothorax at Very Low Dose MDCT after Intervention. How Low Can We Go? Scientific Abstract presentation at R.S.N.A. 2013 12. Assessing Viable Tissue within Hepatocellular Carcinoma (HCC) Lesions after Locoregional Therapy: A Comparison between Modified RECIST (mRECIST) and Volumetric Quantification Scientific Abstract presentation at R.S.N.A. 2013 13. Reproducibility of mRECIST and Volumetric Quantification of Viable Tissue in HCC Lesions Scientific Abstract presentation at R.S.N.A. 2013 14. Effects of Different Voltages and Tube Currents on MDCT Attenuation of Vertebral Trabecular Bone Using Different Reconstruction Algorithms – Scientific Poster presentation at R.S.N.A., 2013 15. The Validity of a Free Breathing Motion Corrected Phase Sensitive Inversion Recovery sequence in the detection of Delayed Myocardial Enhancement in Non-Ischemic Heart Disease, Scientific Poster Presentation at S.C.M.R. 2014 16. Application of feature tracking at cine Cardiac MR for the semi-automated prediction of normal right ventricular systolic function: A feasibility Study Scientific Poster Presentation at S.C.M.R. 2014 17. Volumetric Quantification of Treatment Response to loco regional Therapy In Hepatocellular Carcinoma (HCC) Scientific Abstract Presentation at A.R.R.S. 2014 18. Effect of reconstruction algorithm on semi-automated quantification of liver lesion size and density at MDCT, Scientific Abstract Presentation at A.R.R.S., 2014 19. Free breathing (FB) motion corrected (MOCO) SSFP delayed enhanced imaging of left ventricular scar in patients with non-ischemic cardiomyopathy. Scientific Abstract at ISMRM Annual Meeting, 2014 20. The validity of a free breathing motion corrected phase sensitive inversion recovery sequence in the detection of delayed myocardial enhancement at 3T. Scientific Abstract Presentation at ISMRM Annual Meeting, 2014 21. Cardiac MR derived myocardial global strain in biopsy-proven non-ischemic cardiomyopathies: A feasibility study AHA CVRI Young Investigator Award finalist at NASCI Annual Meeting, 2014 Travel Award recipient at the MRA Club 2015 22. The Transition to Quantitative Cardiac Imaging: Navigating Quantitative Maps Where Do We Stand and Where Do We Go from Here? Educational exhibit presented at R.S.N.A., 2014 23. “Heart of Brightness” Delayed Enhancement Detection using Motion Corrected (MOCO) Phase Sensitive Inversion Recovery (PSIR) Imaging in Non-ischemic Cardiomyopathy Scientific Paper presented at R.S.N.A. 2014 24. Low Dose CT Angiography for Pre-procedural Assessment of Patients Undergoing TAVI Scientific Poster presented at R.S.N.A., 2014 25. Cardiac MR feature tracking identifies abnormal biventricular global strain values in biopsy Proven non-ischemic cardiomyopathies Scientific Paper presented at S.C.M.R 2015 26. Evaluation of late gadolinium enhancement in non-ischemic cardiomyopathy at 3T using motion corrected free breathing single shot SSFP, Scientific Paper presented at I.S.M.R.M., 2015 27. Accelerated segmented and real-time aortic flow sequences compared with standard 2D phase contrast MR in children Scientific Paper presented at S.P.R 2015 28. Reduction in Metal Susceptibility Artifact from Hip Prostheses Using QISS with Fast Low Angle Shot Readout, Scientific Paper presented at R.S.N.A. 2015 29. Breath-hold imaging of the coronary arteries using quiescent-interval slice-selective (QISS) magnetic resonance angiography pilot study at 1.5 tesla and 3 Tesla Scientific Paper presented at S.C.M.R. 2016 30. Rapid imaging of peripheral vascular calcifications using in-phase, two-dimensional radial FLASH at 3 Tesla Scientific Paper presented at S.C.M.R. 2016 31. Comprehensive non-contrast MR assessment of the iliofemoral arteries with visualization of vascular calcifications in TAVR candidates initial experience Scientific Paper presented at S.C.M.R. 2016 32. Dark Blood Imaging of the Heart using Dual-Inversion, Balanced Steady-State Free Precession, Scientific Paper presented at S.C.M.R. 2016 33. Super-Resolution Quiescent-Interval Slice-Selective Magnetic Resonance Angiography of the Intracranial Circulation– Scientific Paper presented at SMRA 2016 34. QISS non-contrast MRA for assessment of the iliofemoral arteries in TAVR candidates – Scientific Paper presented at SMRA 2016 35. MRI imaging for aortic annular sizing – Scientific Paper presented at SMRA 2016 36. Assessment of Contrast Enhanced MRA Volumetry to Detect Growth of the Ascending Aorta in Patients with Bicuspid Aortic Valves - Scientific Paper presented at R.S.N.A. 2016 37. Improved Dark Blood Imaging of the Heart using Dual-Inversion, Balanced Steady-State Free Precession, Scientific Paper presented at S.C.M.R. 2017 38. The spectrum of Pulmonary Sequestrations – Pre- and Post-natal Imaging - Scientific Paper to be presented at SPR 2017