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NM ORDERING GUIDE Table of Contents CARDIAC Myocardial Perfusion Scan MUGA Scan IMG5491 IMG430 2 3 SKELETAL Whole Body Bone Scan Triple Phase Bone Scan Limited Body Bone Scan Multi-Body Bone Scan SPECT Bone Scan IMG401 IMG402 IMG399 IMG400 IMG8571 4 5 6 7 8 GASTROINTESTINAL Gastric Emptying Scan GI Bleed Scan HIDA w/Ejection Fraction Liver/Spleen Scan Meckels Diverticulum Scan IMG388 IMG394 IMG8575 IMG379 IMG396 9 10 11 12 13 PULMONARY Lung VQ Scan Lung Quantification Scan IMG5257 IMG442 14 15 ENDOCRINE Thyroid Uptake & Scan Parathyroid Scan Iodine 131 Whole Body Imaging IMG344 IMG351 IMG349 16 17 18 GENITOURINARY Renal Scan w/Lasix Renal Scan w/Captopril Renal Cortical Imaging IMG1161 IMG2149 IMG8616 19 20 21 ABSCESS/INFECTION Indium 111 Tagged WBC LTD Indium 111 Tagged WBC WB Triple Phase Bone Scan Gallium 67 Abscess/Infection Scan IMG1167 IMG1170 IMG402 IMG2410 22 23 24 25 TUMOR/ONCOLOGY Sentinel Node Lymphatic Imaging Octreotide Scan Gallium 67 Tumor Imaging IMG372 IMG8579 IMG8580 26 27 28 MYOCARDIAL PERFUSION SCAN EXAM CODE: BACK IMG5491 - NM MYOCARDIAL PERFUSION MULT SPECT INDICATIONS: • Detection and evaluation of coronary artery disease, coronary atherosclerosis, myocardial infarction, and history of heart disease. • Evaluation of precordial pain, abnormal EKG, and abnormal cardiac laboratory findings. RADIOPHARMACEUTICAL & DOSE: • 10 millicuries Technetium 99m sestamibi • 30 millicuries Technetium 99m sestamibi PATIENT PREPARATION: • NPO after midnight prior to scan. • No caffeine 12 hours prior to scan. • Check with Exam for medication hold list. PROCEDURE: • For most patients, both resting and stress scan are done on the same day. • Patient is intravenously injected with isotope followed by a resting scan. • A chemical or treadmill stress test will be performed during which another intravenous injection of isotope will occur. • The stress images will then be performed last. TOTAL EXAM TIME: • 3-4 hours for entire procedure REMINDERS: • • • • • NPO after midnight. No caffeine 12 hours prior to scan. Discontinue indicated meds per physician. Total exam time is 3-4 hours. Two-day patient studies will return the following day for injection and imaging (2 hours). NM Ordering Guide | Updated: 7.22.13 2 MUGA SCAN (Tagged RBC Imaging) EXAM CODE: BACK IMG430 - NM CARDIAC BLOOD POOL GATED SPECT W EF INDICATIONS: • Assessment of left ventricle ejection fraction and cardiac wall motion. • Scan is typically performed prior to chemotherapy administration. RADIOPHARMACEUTICAL & DOSE: • 30 millicuries Technetium 99m RBC (tagged red blood cells) PATIENT PREPARATION: • No caffeine 24 hours prior to exam. • No PET scan within last 24 hours. • 20g IV catheter or larger for RBC blood draw. PROCEDURE: • The patient will have a blood sample collected. • Patient’s red blood cells will be tagged to an isotope and intravenously injected 30 minutes post blood sample collection. • Gated planar imaging of the heart will be performed for 20 minutes. • SPECT tomographic images will also be taken for additional 20 minutes. TOTAL EXAM TIME: • 2 hours for entire procedure. REMINDERS: • Total exam time is 2 hours. • No PET scan within last 24 hours REMINDERS: • 20g IV catheter or larger for RBC blood draw. NM Ordering Guide | Updated: 7.22.13 3 WHOLE BODY BONE SCAN EXAM CODE: BACK IMG401 - NM BONE SCAN WHOLE BODY INDICATIONS: • Detection and evaluation of primary and metastatic disease of the bones, Paget’s disease of the bone, neoplasm, or known lesions. • Evaluation of abnormal x-rays or abnormal laboratory results such as; elevated alkaline phosphatase and elevated prostate specific antigen (PSA). RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after the bone scan injection. • Please provide current x-rays taken of any areas of interest for radiological comparison. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 3 hours later for whole body imaging. TOTAL EXAM TIME: • 15 minutes for injection. • 1 hour for delayed whole body bone imaging. REMINDERS: • • • There is no patient preparation for this exam. The patient will receive an injection and will return about 3 hours later for imaging. Please provide any current and relative films for exam. NM Ordering Guide | Updated: 7.22.13 4 TRIPLE PHASE BONE SCAN EXAM CODE: BACK IMG402 - NM BONE SCAN 3 PHASE SCAN INDICATIONS: • Assessment of loosening or infected prosthesis, infection of extremities, and detection of osteomylitis. RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after the bone scan injection. • Please provide any current x-rays taken of the area of interest for radiological comparison to the triple phase bone scan. PROCEDURE: • Patient will receive intravenous injection of isotope. • During injection, blood flow images are taken of the area of interest, followed by blood pool images of the same area. • The patient will return 3 hours later for static bone imaging. TOTAL EXAM TIME: • 30 minutes for injection and blood flow imaging. • 1 hour for delayed bone imaging. REMINDERS: • • • • There is no patient preparation for this exam. The patient will receive an injection with immediate imaging, and will return about 3 hours later for delayed imaging. Please note the specific area of interest on physician order. Please provide any current and relative films for indicated area. NM Ordering Guide | Updated: 7.22.13 5 LIMITED BODY BONE SCAN EXAM CODE: BACK IMG399 - NM BONE SCAN LIMITED INDICATIONS: • Evaluation limited to one specific area of interest for abnormal x-rays, pain, trauma, occult fractures, neoplasm or known lesions. RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after the bone scan injection. • Please provide any current x-rays taken of the area of interest for radiological comparison. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 3 hours later for limited static imaging of area indicated for scan. TOTAL EXAM TIME: • 15 minutes for injection. • 1 hour for delayed bone imaging. REMINDERS: • • • • There is no patient preparation for this exam. The patient will receive an injection and will return about 3 hours later for imaging. Please note the specific area of interest on physician order. Please provide any current and relative films for indicated area. NM Ordering Guide | Updated: 7.22.13 6 MULTI BODY BONE SCAN EXAM CODE: BACK IMG400 - NM BONE SCAN MULTIPLE INDICATIONS: • Evaluation two or more specific areas of interest for abnormal x-rays, pain, trauma, occult fractures, neoplasm or known lesions. RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure; however the patient will be instructed to hydrate after the bone scan injection. • Please provide any current x-rays taken of the areas of interest for radiological comparison. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 3 hours later for multiple static imaging of areas indicated for scan. TOTAL EXAM TIME: • 15 minutes for injection. • 1 hour for delayed bone imaging. REMINDERS: • • • • There is no patient preparation for this exam. The patient will receive an injection and will return about 3 hours later for imaging. Please note the specific areas of interest on physician order. Please provide any current and relative films for indicated areas. NM Ordering Guide | Updated: 7.22.13 7 SPECT BONE SCAN EXAM CODE: BACK IMG8571 - NM BONE SCAN MULTIPLE W SPECT INDICATIONS: • Evaluation of back pain specific to the spine. RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after the bone scan injection. • Please provide current x-rays taken of area of interest for radiological comparison. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 3 hours later for tomographic imaging of the spine. TOTAL EXAM TIME: • 15 minutes for injection. • 1 hour for delayed whole body bone imaging. REMINDERS: • • • • There is no patient preparation for this exam. The patient will receive an injection and will return about 3 hours later for imaging. Please note the specific area of interest on physician order. Please provide any current and relative films for exam. NM Ordering Guide | Updated: 7.22.13 8 GASTRIC EMPTYING SCAN EXAM CODE: BACK IMG388 - NM GASTRIC EMPTYING INDICATIONS: • Evaluation of gastric emptying, pain, bloating, gastric regurgitation, diabetic gastroparesis, nausea and vomiting. RADIOPHARMACEUTICAL & DOSE: • 1 millicurie Technetium 99m SC (sulfur colloid) PATIENT PREPARATION: • NPO after midnight prior to scan. • Discontinue sedatives 12 hours prior to scan. PROCEDURE: • Patient eats a small isotope labeled meal consisting of 1 scrambled egg and 2 pieces of toast. • After meal is consumed images will be taken every hour for up to 4 hours. • Data will be processed and a percent of gastric emptying will be graphed on a time activity curve. TOTAL EXAM TIME: • 2-4 Hours for entire procedure. REMINDERS: • • • Patient NPO after midnight prior to scan. Discontinue sedatives 12 hours prior to scan. Total exam time is 2 hours. NM Ordering Guide | Updated: 7.22.13 9 GASTROINTESTINAL BLEED SCAN (Tagged RBC Scan) EXAM CODE: BACK IMG394 - NM GI BLOOD LOSS INDICATIONS: • Detection and localization of acute gastrointestinal bleeding. RADIOPHARMACEUTICAL & DOSE: • 30 millicuries Technetium 99m RBC (tagged red blood cells) PATIENT PREPARATION: • No patient prep, scan is typically ordered on an acute basis either from the ER, ICU, or unit floor. • 20g IV catheter or larger for RBC blood draw. PROCEDURE: • The patient will have a blood sample collected. • Patient’s red blood cells will be tagged to an isotope and intravenously injected 30 minutes post blood sample collection. • Imaging will start immediately after isotope injection. • Dynamic images of the abdominal cavity will be taken for approximately 1 hour. TOTAL EXAM TIME: • 2 hours for entire procedure. REMINDERS: • • • No patient preparation for exam. 20g IV catheter or larger for RBC blood draw. Total exam time is 2 hours. NM Ordering Guide | Updated: 7.22.13 10 HIDA SCAN W/ EJECTION FRACTION (Hepatobiliary or Gallbladder Imaging) EXAM CODE: BACK IMG8575 – NM HEPATOBILIARY W CCK W VASCULAR FLOW INDICATIONS: • Evaluation of biliary system for acute cholecystitis, cholelithiasis, biliary tree function and biliary leak after surgery. • Evaluation of abdominal pain and/or right upper quadrant (RUQ) pain. RADIOPHARMACEUTICAL & DOSE: • 4 millicuries Technetium 99m Choletec (mebrofenin) PATIENT PREPARATION: • NPO 4-12 hours prior to scan. • Discontinue opiate-based medications 4 hours prior to scan. PROCEDURE: • Patient will receive intravenous injection of isotope. • Dynamic imaging will be performed for 60 minutes. • For ejection fraction the patient will be given Kinevac (sincalide) to stimulate gallbladder contraction. • Dynamic ejection fraction images will be taken for another 30 minutes and will determine percent excretion of gallbladder. TOTAL EXAM TIME: • 2 hours for entire procedure. REMINDERS: • • • NPO 4-12 hours prior to scan Hold opiate based meds 4 hours prior to scan. Total exam time is 2 hours. NM Ordering Guide | Updated: 7.22.13 11 LIVER/SPLEEN SCAN EXAM CODE: BACK IMG379 - NM LIVER SPLEEN SCAN W VASCULAR FLOW INDICATIONS: • Detection and localization of hepatic tumors, abscesses, cysts, and hematomas. • Evaluation of thrombocytopenia and hepatic diseases such as cirrhosis and fatty infiltration. • Evaluation of anatomy, size, and position of the liver and spleen. RADIOPHARMACEUTICAL & DOSE: • 10 millicuries Technetium 99m SC (sulfur colloid) PATIENT PREPARATION: • NPO 4 hours. PROCEDURE: • Patient is intravenously injected with isotope. • Imaging starts 15 minutes post injection. • Static images are taken in various projections for approx. 45 minutes. TOTAL EXAM TIME: • 1 hour for entire procedure. REMINDERS: • • Patient must be NPO for at least 4 hours. Total exam time is 1 hour. NM Ordering Guide | Updated: 7.22.13 12 MECKELS DIVERTICULUM SCAN EXAM CODE: BACK IMG396 – NM MECKELS DIVERTICULUM INDICATIONS: • Detection and evaluation of meckels diverticulum. • Localization of functional gastric mucosa not found in the stomach. RADIOPHARMACEUTICAL & DOSE: • 10 millicuries Technetium TC04 (sodium pertechnetate) PATIENT PREPARATION: • There is no prep for this procedure. PROCEDURE: • Patient will receive intravenous injection of isotope. • Imaging will start immediately after isotope injection. • Dynamic images will be taken for approximately 1 hour. TOTAL EXAM TIME: • 90 minutes for entire procedure. REMINDERS: • • There is no patient preparation for this exam. Total exam time is 90 minutes. NM Ordering Guide | Updated: 7.22.13 13 LUNG VENTILATION & PERFUSION SCAN (Lung VQ Scan) EXAM CODE: BACK IMG5257 - NM LUNG PERFUSION VENTILATION INDICATIONS: • Detection and evaluation of pulmonary embolism (PE). RADIOPHARMACEUTICAL & DOSE: • 15 millicuries Xenon 133 gas • 5 millicuries Technetium 99m MAA (macro-aggregated albumin) PATIENT PREPARATION: • Obtain a recent chest x-ray within 24 hours to correlate with lung scan. PROCEDURE: • Ventilation images are acquired first followed by the perfusion imaging. • Dynamic ventilation images are taken for 5 minutes while patient breathes in isotope. • Patient is then intravenously injected with isotope for perfusion imaging. • Static perfusion imaging is performed in various projections for approx. 20 minutes. TOTAL EXAM TIME: • 1 Hour for entire procedure. REMINDERS: • • Patient needs a chest x-ray within 24 hours to correlate with lung scan. Patient must be able to remain off administered oxygen for 6 minutes to complete ventilation study. NM Ordering Guide | Updated: 7.22.13 14 LUNG QUANTITATION SCAN EXAM CODE: BACK IMG442 - NM LUNG DIFFERENTIAL PERF VENT INDICATIONS: • A pre-operative evaluation to access regional lung functions. RADIOPHARMACEUTICAL & DOSE: • 15 millicuries Xenon 133 gas • 5 millicuries Technetium 99m MAA (macro-aggregated albumin) PATIENT PREPARATION: • Obtain a recent chest x-ray within 24 hours to correlate with lung scan. PROCEDURE: • Ventilation images are acquired first followed by the perfusion imaging. • Dynamic ventilation images are taken for 5 minutes while patient breathes in isotope. • Patient is intravenously injected with isotope for perfusion imaging. • Static perfusion imaging is performed in various projections for approx. 20 minutes. • Image processing will determine regional lung quantification. TOTAL EXAM TIME: • 1 Hour for entire procedure. REMINDERS: • • Patient needs a chest x-ray within 24 hours to correlate with lung scan. Patient must be able to remain off administered oxygen for 6 minutes to complete ventilation study. NM Ordering Guide | Updated: 7.22.13 15 THYROID UPTAKE AND SCAN EXAM CODE: BACK IMG344 - NM THYROID UPTAKE AND SCAN MULTIPLE INDICATIONS: • Detection and evaluation of hypothyroidism, hyperthyroidism, toxic and non-toxic nodules, goiter, and differentiation of benign from malignant nodules. RADIOPHARMACEUTICAL & DOSE: • 500 microcuries Iodine 123 sodium iodine capsule PATIENT PREPARATION: • Discontinue thyroid medications 4 weeks prior to scan. • No intravenous iodinated contrast 4 weeks prior to scan. • NPO after midnight. • Avoid large amounts of salt prior to scan. • Current thyroid labs available to NM department. • Related study information available to NM department. PROCEDURE: • Isotope is administered orally in pill form. • Patient returns 4 hours later for imaging and uptake to determine percent localization of isotope in thyroid. • The patient also returns the following morning for a 24 hour uptake. TOTAL EXAM TIME: • Patient assessment and isotope administration 30 minutes. • 4 Hour uptake and scan will take approx. 1 hour. • 24 Hour uptake only requires 15 minutes. REMINDERS: • • • • • Discontinue thyroid meds 4 weeks prior to exam. NPO after midnight. Current thyroid labs available to NM department. Related study information (ultrasound) available to NM department. Patient will return to NM department at 4 hrs and 24 hrs for imaging & uptake. NM Ordering Guide | Updated: 7.22.13 16 PARATHYROID SCAN EXAM CODE: BACK IMG351 - NM PARATHYROID SCAN INDICATIONS: • Evaluation of hyperparathyroidism to detect parathyroid adenomas. RADIOPHARMACEUTICAL & DOSE: • 20 millicuries Technetium 99m sestamibi PATIENT PREPARATION: • Patient needs to discontinue thyroid medications and calcium medications for 1 week. • No previous iodinated contrast studies for 2 weeks prior to scan. PROCEDURE: • Patient is intravenously injected with isotope. • Immediate static imaging of parathyroid and thyroid glands from multiple projections. • Delayed static images are then acquired 90 minutes post isotope injection. TOTAL EXAM TIME: • 3 hours for entire procedure. REMINDERS: • • • • Patient needs to discontinue thyroid and calcium meds for 1 week prior to exam. No previous iodinated contrast studies for 2 weeks prior to exam. Current thyroid/parathyroid labs available to NM department. Total exam time is 3 hours. NM Ordering Guide | Updated: 7.22.13 17 IODINE 131 WHOLE BODY IMAGING EXAM CODE: BACK IMG349 - NM THYROID CANCER METASTATIC SCAN WHOLE BODY INDICATIONS: • Detection and localization of residual thyroid tissue post thyroidectomy. • Evaluation of recurrent thyroid carcinoma. RADIOPHARMACEUTICAL & DOSE: • 1-5 millicuries Iodine 131 sodium iodine capsule. PATIENT PREPARATION: • Patient is required to have 2 forms of identification. • Discontinue thyroid medications 4 weeks prior to scan. • No intravenous iodinated contrast within 4 weeks prior to scan. • NPO after midnight. • Avoid large amounts of salt and seafood prior to scan. PROCEDURE: • Isotope is administered orally in pill form. • Whole body imaging is then performed at 24 & 48 hours after isotope administration. TOTAL EXAM TIME: • 30 minutes for isotope administration. • 1 hour for whole body imaging each day. REMINDERS: • • • • • Patient is required to have 2 forms of identification. Discontinue thyroid medications x 4 weeks. No IV contrast x 4 weeks. NPO after midnight. Imaging is performed at 24 and 48 hours post dose administration. NM Ordering Guide | Updated: 7.22.13 18 RENAL SCAN W/LASIX WASHOUT (Flow & Function w/Lasix Washout) EXAM CODE: BACK IMG1161 - NM KIDNEY W FLOW AND FUNCTION W DIURETIC INDICATIONS: • Evaluation of renal function, vascular flow, drainage, obstruction, and differential renal function RADIOPHARMACEUTICAL & DOSE: • 10 millicuries Technetium MAG3 (mercaptoacetyltriglycine) PATIENT PREPARATION: • Patient is to be well hydrated and should void before test begins. • Patient should discontinue angiotensin converting enzyme (ACE) inhibitors. PROCEDURE: • Patient is intravenously injected with an isotope; flow and function images are immediately acquired. • Once renal pelvises are full, Lasix is administered at 0.5 mg/kg up to 40 mg to obtain a Lasix washout. • Pre and Post void images are also acquired. TOTAL EXAM TIME: • 1.5 hours for entire procedure. REMINDERS: • • Patient needs to be well hydrated prior to exam. ACE inhibitors should be discontinued for exam. NM Ordering Guide | Updated: 7.22.13 19 RENAL SCAN W/CAPTOPRIL (Flow & Function w/Captopril) EXAM CODE: BACK IMG2149 - NM KIDNEY W FLOW & FUNCTION W WO CAPTOPRIL INDICATIONS: • Detection and Evaluation of renovascular hypertension. RADIOPHARMACEUTICAL & DOSE: • 10 millicuries Technetium MAG3 (mercaptoacetyltriglycine) PATIENT PREPARATION: • Patient should be well hydrated prior to exam. • Patient should discontinue captopril meds 48 hours prior to exam. • Patient should discontinue enalapril and lisinopril medications for 1 week prior to exam. PROCEDURE: • The Captopril exam is performed first. • On day of Captopril exam patient will be given 50mg Captopril and have blood pressure monitored for 1 hour prior to imaging. • Flow and functional images are then performed. • On day of Baseline exam flow & functional images are performed without using Captopril stimulation. • The Captopril and Baseline exams should be performed no sooner than 48 hours between each other, then compared to evaluate for renovascular hypertension. TOTAL EXAM TIME: • 2 hours for Captopril exam. • 1 hour for Baseline exam. REMINDERS: • • • Patient needs to be well hydrated prior to exam. Patient should discontinue Captopril meds for 48 hrs prior to exam. Captopril and baseline scans are performed no sooner than 48 hrs between each other. NM Ordering Guide | Updated: 7.22.13 20 RENAL CORTICAL IMAGING EXAM CODE: BACK IMG8616 - NM KIDNEY MORPHOLOGY INDICATIONS: • Assessment of the renal cortex for scarring, infarct, or renal mass, and evaluation of renal transplant. RADIOPHARMACEUTICAL & DOSE: • 6 millicuries Technetium 99m DMSA (dimercaptosuccinic acid) PATIENT PREPARATION: • Patient is to be well hydrated and should void before test begins. • Patient should discontinue angiotensin converting enzyme (ACE) inhibitors. PROCEDURE: • Patient will receive intravenous injection of isotope and return 3 hours later for imaging. • Patient should continue hydrating between injection and acquisition of images. • Static imaging of kidneys will be performed in multiple projections. TOTAL EXAM TIME: • 15 minutes for injection. • 1 hour for delayed renal imaging. REMINDERS: • • • Patient needs to be well hydrated prior to exam. ACE inhibitors should be discontinued for exam. Patient will return 3 hours after injection for imaging. NM Ordering Guide | Updated: 7.22.13 21 INDIUM 111 WBC LIMITED BODY IMAGING (Indium 111 Tagged WBC) EXAM CODE: BACK IMG1167 - NM INFLAMMATORY WBC W INDIUM111 LIMITED INDICATIONS: • Detection and evaluation of osteomylitis, infected joint prosthesis, abscess, or infection. RADIOPHARMACEUTICAL & DOSE: • 500 microcuries Indium 111 WBC (tagged white blood cells) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after injection. PROCEDURE: • The patient will arrive the morning of procedure to have a blood sample collected. • Patient will return 4 hours later for white cell labeled intravenous isotope injection. • The patient will be instructed to return the following day for delayed 24 hour imaging. TOTAL EXAM TIME: • 30 minutes for blood sample collection. • 15 minutes for labeled white cell injection. • 45 minutes for the delayed images done at 24 hours post isotope injection. REMINDERS: • • • • • There is no patient preparation for this exam. Patient will need to hydrate after injection Patient will return at 4 hours for isotope injection and at 24 hours for imaging. Please note the specific area of interest on physician order. Please provide any current and relative films for indicated area. NM Ordering Guide | Updated: 7.22.13 22 INDIUM 111 WBC WHOLE BODY IMAGING (Indium 111 Tagged WBC) EXAM CODE: BACK IMG1170 - NM INFLAMMATORY WBC WHOLE BODY W INDIUM111 INDICATIONS: • Evaluation of fever of unknown origin. • Detection and evaluation of osteomylitis, infected joint prosthesis, abscess, or infection. RADIOPHARMACEUTICAL & DOSE: • 500 microcuries Indium 111 WBC (tagged white blood cells) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after injection. PROCEDURE: • The patient will arrive the morning of procedure to have a blood sample collected. • Patient will return 4 hours later for white cell labeled intravenous isotope injection. • The patient will be instructed to return the following day for delayed 24 hour imaging. TOTAL EXAM TIME: • 30 minutes for blood sample collection. • 15 minutes for labeled white cell injection. • 45 minutes for the delayed images done at 24 hours post isotope injection. REMINDERS: • • • There is no patient preparation for this exam. Patient will need to hydrate after injection. Patient will return at 4 hours for isotope injection and at 24 hours for imaging. NM Ordering Guide | Updated: 7.22.13 23 TRIPLE PHASE BONE SCAN EXAM CODE: BACK IMG402 - NM BONE SCAN 3 PHASE SCAN INDICATIONS: • Assessment of loosening or infected prosthesis, infection of extremities, and detection of osteomylitis. RADIOPHARMACEUTICAL & DOSE: • 25 millicuries Technetium 99m MDP (methylene diphosphonate) PATIENT PREPARATION: • There is no prep for this procedure, however the patient will be instructed to hydrate after the bone scan injection. • Please provide any current x-rays taken of the area of interest for radiological comparison to the triple phase bone scan. PROCEDURE: • Patient will receive intravenous injection of isotope. • During injection, blood flow images are taken of the area of interest, followed by blood pool images of the same area. • The patient will return 3 hours later for static bone imaging. TOTAL EXAM TIME: • 30 minutes for injection and blood flow imaging. • 1 hour for delayed bone imaging. REMINDERS: • • • • There is no patient preparation for this exam. The patient will receive an injection with immediate imaging, and will return about 3 hours later for delayed imaging. Please note the specific area of interest on physician order. Please provide any current and relative films for indicated area. NM Ordering Guide | Updated: 7.22.13 24 GALLIUM 67 ABSCESS/INFECTION SCAN EXAM CODE: BACK IMG2410 - NM ABSCESS LOCALIZATION WHOLE BODY W GALLIUM INDICATIONS: • Detection and evaluation of inflammatory processes, fever of unknown origin, osteomylitis and disc space infection. RADIOPHARMACEUTICAL & DOSE: • 5 millicuries Gallium 67 citrate PATIENT PREPARATION: • Patient should remain well hydrated throughout the course of the examination. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 6 hours later for whole body imaging. • The patient will also have whole body imaging performed at 24 and 48 hours post isotope injection. • Optional SPECT tomographic imaging may also be performed in conjunction with whole body imaging. TOTAL EXAM TIME: • 15 minutes for injection. • Delayed imaging done at 6, 24, and 48 hours will take approximately 1 hour each day. REMINDERS: • • • Patient should remain well hydrated throughout exam. Patient will return at 6, 24, and 48 hours for imaging. Imaging times are about 1 hour each day. NM Ordering Guide | Updated: 7.22.13 25 SENTINEL NODE LOCALIZATION (Lymphatic Imaging) EXAM CODE: BACK IMG372 - NM LYMPHATICS LYMPH NODE INDICATIONS: • Localization and evaluation of sentinel node in patients with breast cancer or melanoma. RADIOPHARMACEUTICAL & DOSE: • Four 500 microcurie doses of Technetium 99m SC (sulfur colloid) PATIENT PREPARATION: • There is no prep for this procedure, however breast cancer patients need current mammography & Ultrasound films available for radiologist evaluation prior to injection. PROCEDURE: • The patient receives 4 small intradermal injections of isotope around the lesion. • Dynamic flow images are acquired immediately following the injection. • Static imaging will then be performed of the area of interest. TOTAL EXAM TIME: • For patients with breast cancer the total exam time is 30-60 minutes. • Total exam time for patients with melanoma is 60-90 minutes. REMINDERS: • • There is no prep for this procedure. Breast cancer patients need current mammography and ultrasound films available for radiologist evaluation prior to injection. NM Ordering Guide | Updated: 7.22.13 26 OCTREOTIDE SCAN (Somatostatin Receptor Imaging) EXAM CODE: BACK IMG8579 - NM TUMOR OCTREOSCAN WHOLE BODY > 2 DAY INDICATIONS: • Detection and localization of neuroendocrine tumors bearing somatostatin receptors such as; carcinoids, neuroblastomas, small cell lung cancer, gastrinoma, islet cell tumor of the pancreas, meningiomas, pheochromocytomas, paragangliomas, pituitary adenomas, and medullary thyroid cancer. RADIOPHARMACEUTICAL & DOSE: • 6 millicuries Indium 111 Pentetreotide (Octreotide labeled peptides) PATIENT PREPARATION: • Patient is to be well hydrated before and after injection. • A mild laxative will be used the evening before imaging and continued with light meals recommended and clear liquids until all images are completed. PROCEDURE: • Patient will receive intravenous injection of isotope and return 4 hours later for whole body imaging. • The patient will also have whole body imaging performed at 24 and 48 hours post isotope injection. • Optional SPECT tomographic imaging may also be performed in conjunction with whole body imaging. TOTAL EXAM TIME: • 15 minutes for injection. • Delayed imaging done at 4, 24, and 48 hours will take approximately 1 hour each day. REMINDERS: • • • Patient should remain well hydrated before and after isotope injection. Patient will return at 4, 24, and 48 hours for imaging. Imaging times are about 1 hour each day. NM Ordering Guide | Updated: 7.22.13 27 GALLIUM 67 TUMOR IMAGING EXAM CODE: BACK IMG8580 - NM TUMOR GALLIUM WHOLE BODY > 2 DAY W SPECT INDICATIONS: • Detection and evaluation of Hodgkin’s disease, Non-Hodgkin’s and Burkitt’s lymphoma. RADIOPHARMACEUTICAL & DOSE: • 5 millicuries Gallium 67 citrate PATIENT PREPARATION: • Patient should remain well hydrated throughout the course of the examination. PROCEDURE: • Patient will receive intravenous injection of isotope. • The patient will return 6 hours later for whole body imaging. • The patient will also have whole body imaging performed at 24 and 48 hours post isotope injection. • Optional SPECT tomographic imaging may also be performed in conjunction with whole body imaging. TOTAL EXAM TIME: • 15 minutes for injection. • Delayed imaging done at 6, 24, and 48 hours will take approximately 1 hour each day. REMINDERS: • • • Patient should remain well hydrated throughout exam. Patient will return at 6, 24, and 48 hours for imaging. Imaging times are about 1 hour each day. NM Ordering Guide | Updated: 7.22.13 28