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7.1 Chromosomes and Phenotype Bell Ringer • Read the quote in small black text (under • connecting concepts) on page 199. Why is • there such a variation in eye color? 7.1 Chromosomes and Phenotype KEY CONCEPT The chromosomes on which genes are located can affect the expression of traits. 7.1 Chromosomes and Phenotype Two copies of each autosomal gene affect phenotype. • Mendel studied autosomal gene traits, like hair texture. 7.1 Chromosomes and Phenotype • Mendel’s rules of inheritance apply to autosomal genetic disorders. – A heterozygote for a recessive disorder is a carrier. – Disorders caused by dominant alleles are uncommon. (dominant) 7.1 Chromosomes and Phenotype “How are Mendel’s observations related to genes on autosomes?” What Mendel studied was due to the expression of 2 copies of autosomal genes. 7.1 Chromosomes and Phenotype Males and females can differ in sex-linked traits. • Genes on sex chromosomes are called sex-linked genes. – Y chromosome genes in mammals are responsible for male characteristics. – X chromosome genes in mammals affect many traits. 7.1 Chromosomes and Phenotype • Male mammals have an XY genotype. – All of a male’s sexlinked genes are expressed. – Males have no second copies of sex-linked genes. 7.1 Chromosomes and Phenotype • Female mammals have an XX genotype. – Expression of sex-linked genes is similar to autosomal genes in females. – X chromosome inactivation randomly “turns off” one X chromosome. 7.1 Chromosomes and Phenotype “Why are males more likely than females to have sex-linked genetic disorders?”