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A. Functional analysis of fibroblasts stimulated by B. burgdorferi sensu stricto strain IBS19 -log(p-value) Threshold 0,0 2,5 5,0 7,5 10,0 12,5 15,0 C. Functional analysis of fibroblasts stimulated by B. afzelii strain IBS17 B. Functional analysis of fibroblasts stimulated by B. garinii strain IBS6 17,5 -log(p-value) Threshold 20,0 22,5 25,0 27,5 30,0 0,0 2,5 5,0 7,5 10,0 12,5 15,0 17,5 -log(p-value) Threshold 20,0 22,5 25,0 27,5 30,0 32,5 0,0 Dermatological Diseases and Conditions Dermatological Diseases and Conditions Dermatological Diseases and Conditions Infectious Disease Immunological Disease Antimicrobial Response Antimicrobial Response Antimicrobial Response Inflammatory Response Inflammatory Response Inflammatory Response Infectious Disease Inflammatory Disease Infectious Disease Immunological Disease Neurological Disease Endocrine System Disorders Inflammatory Disease Skeletal and Muscular Disorders Gastrointestinal Disease Neurological Disease Immunological Disease Metabolic Disease Skeletal and Muscular Disorders Endocrine System Disorders Cell Signaling Endocrine System Disorders Gastrointestinal Disease Inflammatory Disease Gastrointestinal Disease Metabolic Disease Neurological Disease Metabolic Disease Ophthalmic Disease Skeletal and Muscular Disorders Cell Signaling Digestive System Development and Function Cell Death and Survival Ophthalmic Disease Hepatic System Development and Function Ophthalmic Disease Digestive System Development and Function Hepatic System Disease Digestive System Development and Function Hepatic System Development and Function Organ Development Hepatic System Development and Function Hepatic System Disease Cell Death and Survival Hepatic System Disease Organ Development Cancer Organ Development Cellular Movement Organismal Injury and Abnormalities Connective Tissue Disorders Hematological System Development and Function Reproductive System Disease Cellular Movement Immune Cell Trafficking Cell-To-Cell Signaling and Interaction Hematological System Development and Function Cell Death and Survival Cellular Movement Immune Cell Trafficking Connective Tissue Disorders Hematological System Development and Function Cell-To-Cell Signaling and Interaction Cell-To-Cell Signaling and Interaction Immune Cell Trafficking Cancer Cancer Gene Expression Organismal Injury and Abnormalities Hematological Disease Hematological Disease Reproductive System Disease Respiratory Disease Cell Signaling Hematological Disease Cell-mediated Immune Response Cellular Function and Maintenance Respiratory Disease Organismal Injury and Abnormalities Connective Tissue Disorders Tissue Development Renal and Urological Disease Hematopoiesis Renal and Urological Disease Reproductive System Disease Respiratory Disease Cell-mediated Immune Response Cellular Function and Maintenance Renal and Urological Disease Cell Morphology Tissue Development Cell Cycle Hypersensitivity Response Cell Morphology Organismal Survival Tumor Morphology Hypersensitivity Response Tissue Development Cellular Function and Maintenance Tumor Morphology Cellular Development Cellular Development Cardiovascular Disease Cellular Growth and Proliferation Cellular Growth and Proliferation Cellular Development Lymphoid Tissue Structure and Development Hematopoiesis Cellular Growth and Proliferation Cellular Compromise Gene Expression Hematopoiesis Cardiovascular System Development and Function Organismal Survival Cellular Compromise Organismal Development Cell Cycle Organismal Survival Tissue Morphology Cardiovascular Disease Tissue Morphology Cell-mediated Immune Response Skeletal and Muscular System Development and Function Cardiovascular System Development and Function Connective Tissue Development and Function Tissue Morphology Organismal Development Embryonic Development Cardiovascular System Development and Function Gene Expression Skeletal and Muscular System Development and Function Organismal Development Cell Cycle DNA Replication, Recombination, and Repair Cellular Compromise Free Radical Scavenging Free Radical Scavenging Cellular Assembly and Organization Molecular Transport Molecular Transport DNA Replication, Recombination, and Repair DNA Replication, Recombination, and Repair Cardiovascular Disease Renal and Urological System Development and Function Renal and Urological System Development and Function Cellular Response to Therapeutics Cellular Response to Therapeutics Lymphoid Tissue Structure and Development Nervous System Development and Function Lymphoid Tissue Structure and Development Skeletal and Muscular System Development and Function Reproductive System Development and Function Organismal Functions Connective Tissue Development and Function Renal and Urological System Development and Function Lipid Metabolism Embryonic Development Protein Synthesis Small Molecule Biochemistry Nervous System Development and Function Hair and Skin Development and Function Connective Tissue Development and Function Hair and Skin Development and Function Post-Translational Modification Embryonic Development Cellular Response to Therapeutics Protein Folding Molecular Transport Developmental Disorder Hypersensitivity Response Nervous System Development and Function Hereditary Disorder Cell Morphology Developmental Disorder Organ Morphology Tumor Morphology Drug Metabolism Psychological Disorders Carbohydrate Metabolism Hereditary Disorder Reproductive System Development and Function Small Molecule Biochemistry Organ Morphology Small Molecule Biochemistry Amino Acid Metabolism Psychological Disorders Humoral Immune Response Humoral Immune Response Reproductive System Development and Function Protein Synthesis Free Radical Scavenging Lipid Metabolism Hair and Skin Development and Function Vitamin and Mineral Metabolism Post-Translational Modification Protein Folding 2,5 5,0 7,5 10,0 12,5 15,0 17,5 20,0 22,5 25,0 27,5 30,0