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Final study guide Function of circulatory system (transportation, regulation, protection) Composition of blood Plasma (proteins, coagulation factors…) Erythrocytes (function, structures, hemoglobin, most common anemias – iron deficiency, B12 folate deficiency) Leucocytes – granular and agranular – function of different cell lines Platelets – function Erythropoiesis Blood types – transfusion, blood types antigens and antibodies Rh System erythroblastosis fetalis Blood clothing - intrinsic extrinsic pathways – hemophilias - heparin/warfarin(coumadin)/ Vit K deficiency Function of the lymphatic system – interstitial fluid transport, fat, immunological defense. – Cardiac output – factors affecting CO Blood Volume (angiotensin system) Factors influencing blood pressure, edema (lymphatic and / cardiac causes) Cardiac regulation Pulmonary/systemic circulation Arteries structure vaso constriction/ Veins – venus valves, muscle pump, /Capilaries – microcirculation Electrical activity of the heart (SA Node, AV node, Bundle of His, Purkinje system) - ECG Immunity Innate (nonspecific) adaptive (specific) Passive, active Antigen, B cell / T cell immunity, clone selection, memory cell MHC class I, MHC class II Immunoglobulins: IgG, IgM, IgA, IgE, IgD characteristic function Autoimmune diseases Rspiratory system anatomic divisions, conducting zone, gas exchange areas… Lung volumes and capacities/ lung function tests Mechanics of respiration (muscles involved, difference in pressure..) Asthma, Emphysema, fibrosis Hemoglobin role/ inherited defects; 2,3-DPG, gas (O2, CO2) exchange and transport Blood gas/ blood pH/ Acid base balance. Structure of the kidneys Glomerular filtration, reabsorption salt water Acid Base balance renal involvement Diuretic drugs Digestion absorption of Sugars, lipids, proteins Stomach small intestine large intestine: products secreted by or delivered at that aids digestion; what is absorbed at the different structures. Liver, gallbladder, and pancreas (products produced and their function)