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Respiratory
Control
Apneas
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Sleep
Apnea Pulmonary
Genetics Consequencesphysiology
A condition characterized by a
pH= 7.38 and HCO3 = 32.
What is Respiratory acidosis or
Hypoventilation?
A condition where there is waxing
and waning of ventilation during
sleep.
What is Cheyne-Stokes Respiration?
Young Female Patients have more of
these stage-related events than male
patients.
What are REM related apneas?
A patient with recurrent central
apnea is the result of this
mechanism?
What is High Loop Gain?
Hypoventilation during sleep has
this definition.
What is a PCO2 increase greater
than 10 mmHg, or a PCO2 higher
than 50mmHg during sleep
Patient with emergent central apnea
during CPAP titration has this
condition.
What is Complex Sleep Apnea?
A name for central apneas
occurring over five cycles of
hyperpnea and apnea.
What is periodic breathing?
This apneic pattern of
breathing is seen in
premature infants.
What is apnea of prematurity?
These apneas during resting
breathing are completely normal.
What is a post-sigh apnea?
The ICSD2 classification irregular
breathing pattern as a result of ShyDrager syndrome.
What is an apnea secondary to a
neurologic disorder?
A condition where there is a large
tongue, wide spaced
eyes, and
.
obstructive sleep apnea.
What is Down’s syndrome
A 10 year old boy who
exhibits sleep apnea and
hypersomnia that remits
every 3 months has this
condition.
What is Klein-Levin syndrome?
Alanine repeat number of this
gene determines the severity of
the phenotype.
What is Phox2B?
A condition recurrent apneas during
wakefulness and improves during
sleep.
What is RETT syndrome
A knock out mouse for this peptide
exhibits a reduction in hypercapnic
drive as well as spontaneous drop
attacks.
What is orexin?
A person with an AHI >15 has a
1.4OR of developing this
cardiovascular risk factor.
What is a hypertension?
Awakens out of REM apneas during
a PSG, reporting soldiers attacking
and gets out of bed to punch out the
window.
What is REM behavior disorder
or RBD?
An obstructive apnea causes this
specific stress on the left ventricle.
What is increased afterload?
The most consistent behavioral
improvement with CPAP in a
patient with obstructive sleep
apnea syndrome.
What is Excessive Daytime
Sleepiness? Also accept What is
improved Quality of Life?
An arrhythmia occasionaly
seen at the end of an
obstructive apnea that can
be treated with atropine but
better treated with CPAP.
What is heart block?
What muscles are required for
exhalation during normal breathing
at rest?
None, exhalation is passive at rest
The type of obstruction depicted
in the floow-volume loop.
What is an extrathoracic
obstructive?
Define (mathematically) the
respiratory quotient used to calculate
the Aa gradient.
What is the amount of CO2
produced per unit of O2 consumed?
(or some such variation)
Define compliance
Volume/unit pressure
VE = 10L/min, PaCO2 = 50
What VE will reduce the PaCO2 to
40?
12.5L/min