Download hypertensive prescriptions in university of nigeria

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ABSTRACT
BACKGROUND: Drug therapy problems (DTP) pose significant challenges to health
care providers and affect morbidity, mortality and a patients quality of life. There is a
high prevalence of drug therapy problems in a population with diabetes and
hypertension.
OBJECTIVE:
To identify the drug therapy problems that occur in prescriptions of the
diabetic and hypertensive patients; to determine the frequency of their occurrence and
the causes of drug therapy problems and to relate the DTP with the demographics of
the patients.
METHOD: This descriptive retrospective study was conducted at a tertiary institution
using patients medical files that have been diagnosed of both diabetes and
hypertension. Their prescription over a one year period were assessed; data was
collected using a designed data collection form. Data was analyzed using ANOVA.
RESULTS: 92 patients folders with a total of 619 prescriptions were assessed and 407
DTPs Identified, the most common DTP encountered was inappropriate adherence (IA)
(43%) followed by drug interaction (DI) (14%) and wrong drug (WD) (12%) and dose too
high (DTH) (11%). The major cause of the problem being that patients prefers not to
take their medications. There were more females 54.3% than males, more urban
dwellers (59.72%) than rural dwellers (40.22%). Mostly the trading occupation has the
highest no of DTP. The mean age of the subjects was 60-69 age range and they had
the highest frequency of the DTP alongside the 50-59 age groups .The drug therapy
problems are independent of patients social demographic.
CONCLUSION: Early identification of the types and the causes can enhance the
prevention and management of DTPs in type 2 diabetes mellitus (T2DM) with
hypertension. Pharmacists included in the health come team can improve quality of life
of patients with diabetes mellitus and hypertension through pharmaceutical care
practices