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BIOLOGY You know that the carbohydrate and lipids of the food we take in are converted to carbondioxide and water at the end of metabolism liberating energy, and it is this energy that is utilized for life activities and growth.... Didn't you notice Ammu's doubt? Didn't you also have this doubt? What may happen to the proteins in our food? Biology Std. X Sir, then what happens to the proteins in our food? Analyse the given description, form inferences about this and record it in the Science diary. Synthesis of Urea Aminoacids are formed due to the breakdown of proteins. These aminoacids are utilized for the synthesis of new proteins necessary for body building, enzymes and many other substances. During these reactions, many byproducts are formed. Many of these are waste materials which are harmful to the body. Ammonia is a major waste product formed in this way. It is very much harmful to the body. The ammonia formed in the cells diffuses 52 BIOLOGY into the blood and the blood carries it to the liver. In the liver, with the help of enzymes, it combines with CO2 and water, and is converted to a substance called urea. NH3+ CO2+H2O → Urea The formation of urea, known as Urea cycle, takes place in a cyclic manner in several steps. Urea is a relatively less toxic substance which is highly soluble in water. Urea formed in the liver is transferred to blood from where it is eliminated through urine. Like urea, other byproducts of metabolism such as carbondioxide, water, etc., also, in excess in the body adversely affect homeostasis. These are to be removed from the body to avoid such a situation. How are carbondioxide and water removed from the body? List the organs which facilitate this. Planning Aim .................................................................. Materials required .................................................................. Procedure ..................................................................... — Skin — ................................................................... Observation .................................................................. — Urine, the main excretory material in the body, contains mainly water, urea and salts. Let us plan an experiment to test the presence of urea in urine. Using the given description conduct an experiment with your friends, and record the findings in the Science diary. Experiment Add 2 or 3 drops of phenolphthalein to 5 ml of urine. Observe the colour change. Add the enzyme urease into this. Observe the colour change again. Inference .................................................................. .................................................................. Indication Phenolphthalein + Urea → milk colour Urea + Urease → Red colour How is urine formed from blood? Which is the organ that helps this ? 53 BIOLOGY Analysing the given description and Figure 4.1, prepare notes on the structure, position, size, etc., of this organ. ..................................................................................................................... Kidneys Kidneys are the organs which purify blood by eliminating impurities in the form of urine. There is a pair of kidneys in human beings. They are seen against the posterior muscles of the abdominal cavity in the lumbar region, on either side of the vertebral column. They are bean-shaped and are about 11cm long, 5cm broad and 3 cm thick. Each kidney is dark red in colour and weighs about 150g and is covered by a rigid but soft membrane. Blood reaches the kidneys from the heart at high pressure, through the renal artery and returns through the renal vein. About 1100mL. of blood passes through the kidneys per minute. Urea, salts, excess amount of medicines taken into the body, vitamins and other harmful substances that reach the body are filtered and removed from the blood by the kidneys. thoracic cavity adrenal gland kidney vertebral column abdominal cavity ureter urinary bladder urethra Fig - 4.1. Kidneys and associated parts In order to know how kidneys filter and remove impurities from blood, their internal structure is to be understood. Analyse Fig. 4.2, complete the given illustration and present it in the class room. 54 BIOLOGY Cortex Renal artery The outer part where lakhs of micro filters are seen The vessel which carries blood to the kidney Renal vein Medulla The vessel which carries blood from the kidney The inner part where long tubes of the filters are seen Pelvis The part to which urine flows from the filters Pyramid The part to which the collecting ducts of micro filters open Ureter Fig - 4.2. Longitudinal section of kidney Functions The vessel which carries urine from the kidney to the urinary bladder Position, size, shape $ $ Kidneys Internal structure, main parts $ Major blood vessels and their functions $ Each kidney has about twelve lakhs of micro filters inside. These are the nephrons. Nephrons are the basic functional units of kidney. Analysing Figure 4.3, draw inferences about how nephrons are arranged inside the kidney. Fig - 4.3. The arrangement of nephrons in the kidney nephron 55 BIOLOGY Ultrafiltration How might kidneys be filtering out the excretory wastes in the blood? What might be the adaptations facilitating this ? Using the indicators, analyse Figures 4.4 and 4.5. Glomerulus Bowman's capsule Inside the kidney the renal artery breaks up into minute capillary networks which look like a bundle of threads. Each bundle is called glomerulus. Minute pores are present on its walls which effect ultra filtration. Bowman’s capsule is a double-walled cuplike covering surrounding the glomerulus. Helps to collect glomerular filtrate formed as a result of ultra filtration. Renal tubule The vessel connecting the Bowman’s capsule and the collecting duct. The reabsorption of essential substances and elimination of certain waste materials take place. Collecting duct Urine Fig - 4.4. Structure of a nephron afferent vessel efferent vessel Glomerular filtrate Contains water, glucose, amino acids, ions of Sodium, Potassium and Calcium, vitamins, urea, uric acid, creatinine, etc. Fig - 4.5. Ultrafiltration 56 Urine is collected from the nephron. It opens out into the pelvis. BIOLOGY Indicators — Is there any difference in size between afferent and efferent vessels? How does this difference affect the flow of blood? — What is the advantage of the breaking up of the afferent vessel into very minute capillaries inside the Bowman’s capsule? — Will there be any difference in the pressure of blood in the glomerulus in relation to the afferent and efferent vessels? If yes, what is the reason? — What is the necessity of micropores on the capillary wall? You have observed the picture of ultra filtration and the components of the glomerular filtrate. — What are the components of the glomerular filtrate? — What may be the reason for the absence of RBC and protein in the glomerular filtrate? Now you have learnt the composition of the glomerular filtrate. About 127 mL of glomerular filtrate is formed per minute. If the whole of the glomerular filtrate is transformed into urine, a person would have to expel about 180 litres of urine per day. Does this happen? How much urine does an individual expel in a day, on an average? Record your guess. ..................................................................... filterate including water and glucose are essential for the body. While glomerular filtrate flows through the renal tubule, these components are reabsorbed at different parts of the tubule. Along with this, certain substances which are not useful to the body are discharged into the glomerular filtrate. Around 126 mL of glomerular filtrate is reabsorbed and the remaining portion becomes urine. This reaches the ureter through the collecting duct. Subsequently, it is stored temporarily in the urinary bladder situated at the lower part of the abdominal cavity. As and when the bladder fills, the urge to urinate occurs and urine is expelled through the urethra. Components of Urine You know that urine contains water, urea etc. What are the other components of urine? Water 96% Urea 2% Salts and other substances NaCl, KCl, Creatinine, Uric acid, Salts of Phosphorus, Calcium, etc. } 2% The pale yellow colour of urine is due to the pigment called urochrome formed as a result of the break down of haemoglobin. Is it now clear that all of the glomerular filtrate is not converted to urine? What happens to the remaining glomerular filterate? You have learnt that human beings excrete on an average 1.5 litres of urine per day. Is there any difference in this quantity due to the changes in climate? If so, what may be the reason? Many components of the glomerular ..................................................................... 57 BIOLOGY Observe Illustration 4.1., analyse the conditions causing changes in the quantity of urine, and the mechanisms which make this possible and form inferences. ..................................................................................................................... Rainy season/ winter Summer Secretion of ADH decreases Secretion of ADH increases Quantity of urine increases Quantity of urine decreases Illustration - 4.1. When kidneys fail Unhealthy habits and life style influence the health of kidneys to a great extent. Kidneys may fail due to several reasons and life itself may be in danger. Read the details given in Table 4.1., gather more information and prepare a pamphlet on diseases of the kidneys, their symptoms, reasons, etc. Disease Nephritis Chronic renal failure Kidney stone Major Symptoms Reasons Dark coloured and turbid urine, backpain and fever, swelling of the face, ankles and feet. Streptococcus infection, infection of urinary bladder, Autoimmune deficiency syndrome, etc. Anaemia, weight loss, giddiness, vomiting, etc. Urea and other excretory wastes are not filtered out, but retained in the blood itself. Various types of renal diseases, diabetes, hypertension, etc. Pain in the lower abdomen, urinary block, backpain, giddiness and vomiting. Calcium oxalate, calcium phosphate etc., get sedimented in the kidney and ureter as grains. Table - 4.1 Is there any means to sustain life of an individual whose kidneys fail to function? Have you heard of dialysis? What is dialysis? It is the process of purification of the blood 58 by filtering out impurities from it using complex machinery. Dialysis is conducted when both the kidneys fail. Observe Illustration 4.2 and identify the stages of dialysis and record it in the Science diary. BIOLOGY 2. The chemical substance called heparin is mixed with blood to prevent coagulation 1. The blood containing high amount of excretory wastes is collected from the artery 3. Artificial kidney (filters the blood and separates excretory wastes ) Dialysing fluid 4. Purified blood is passed back to vein Illustration - 4.2. Dialysis Kidney Transplantation Given below are the contents of a poster pasted on the wall of a Primary Health Centre. Using this, discuss the significance and limitations of kidney donation and record the details in the Science diary. Collect more information and pictures of kidney donation and display them on the bulletin board. Donate kidneys...... Share life...... • Kidney transplantation becomes necessary in a condition in which both the kidneys completely fail beyond treatment. • The kidney of a healthy individual who dies in an accident (deceased donor) or that of a healthy person (living donor) can be donated. • Whatever be the category of donor, the blood groups of the donor and the recipient must be compatible. • It is a functional kidney that is transplanted from the donor to the recipient. Kidney transplantation is successful only when the recipient’s body completely accepts the kidney. 59 BIOLOGY Other Excretory Organs in the Body You have learnt that the lungs, liver and skin are the other organs which eliminate excretory materials formed in the body. What are the wastes that they expel? How do they function? Analyse the figures and notes given below ( 4.6 to 4.8) and complete Table 4.2. The carbon dioxide formed as a result of metabolic activities is collected and expelled from the body along with water vapour. Fig - 4.6 Lungs The waste management plant that maintains homeostasis by detoxifying most of the toxins that reach the blood. Liver does not directly eliminate excretory materials. Fig - 4.7 Liver Excretory Organs Fig - 4.8 The sweat glands in the skin expel water and wastes like urea and uric acid through sweat. Sweat contains 99% water and 1% salts and other substances. Skin Organ Excretory Materials Method of Elimination Table - 4.2. Like human beings, other animals also have systems to remove wastes formed as metabolic byproducts. But depending on the peculiarities of the circumstances in which they live, they are diverse in structure. Analyse the given description and compare the excretory organs, excretory materials, mechanisms of excretion, etc., of other organisms. Find out the similarities and differences, and the main reasons thereof and record them in the Science diary. 60 BIOLOGY Excretion in Other Organisms Amoeba contractile vacuole Fig - 4.9. There are no excretory organs in amoeba which is a unicellular organism. But this function is performed with the help of contractile vacuoles. Excess water that reaches the body is also expelled through the contractile vacuole. Earthworm Fig - 4.10. Nephridia Nephridia are the excretory organs in earthworm. They separate water, nitrogenous wastes, etc., from the body cavity and expel them through the pores on the body surface. Insects Fig - 4.11. The excretory organs of insects are known as Malpighian tubules. They are minute tubes spread out in the body fluid that fills the body cavity and open out into the alimentary canal. Malpighian tubules separate impurities from the body fluid and carry them to the alimentary canal, from where they are expelled. Malpighian tubule Fish The major excretory material in fish is ammonia, which is excreted directly into water through the kidneys. Fig - 4.12. Frog Nn{Xw 4.13 Fig - 4.13. Kidneys are the organs of excretion in frogs too. In tadpoles which are fully aquatic, ammonia is the excretory material. But when tadpole metamorphose into frog, instead of ammonia, urea is eliminated as the excretory material. Reptiles and Birds Fig - 4.14. Uric acid is the excretory material in birds and reptiles. It is solid or semisolid in form and insoluble in water. This minimises the loss of water through excretion. Kidneys are the excretory organs in them too. Fig - 4.15. 61 BIOLOGY Do Plants Excrete ? Did you notice the question? Read the description given below, observe the plants around you carefully, discuss the findings with friends, and present them in the class. Excretion in Plants In plants too there are mechanisms to eliminate excretory materials formed as a result of metabolic reactions. In plants there is no specific excretory system as in animals. The quantity of wastes formed in plants is also very low compared to that in animals. The main reason for this is said to be the lesser rate of activity in plants when compared to animals. The excess oxygen produced as a byproduct of photosynthesis is eliminated through stomata. Carbon dioxide formed as a result of cell respiration is also expelled through the stomata. From the soil plants absorb more water than required. This excess water is expelled through stomata and hydathodes. Hydathodes are minute pores at the tip of the leaves of plants of the grass species to eliminate water. Water is expelled as vapour through the stomata, and as droplets through the hydathode. Certain excretory products reach the older xylem vessels in the stem and accumulate there. This activity has a significant role in the gradual formation of heart wood. Shedding of leaves is another mechanism for the elimination of excretory products in plants. Plants reabsorb the essential components from leaves as they ripen and fall. Therefore in the falling leaves, excretory materials will be the major content. You have learnt that in order to maintain homeostasis, organisms keep the internal environment free of wastes. If so, shouldn’t we conserve our external environment for the wellbeing of nature and its countless species of living beings? Observe Figure 4.16. Fig - 4.16. 62 BIOLOGY Have you come across such heaps of waste? — What impacts do this bring about? — Enlist them. — — Shouldn’t we put an end to such pollution? How? — Does your school premises get dirty like this? If so, by what all means does it get dirty? Enlist them. The leftover of lunch, packing leaves etc. By group activity, form an action plan to eliminate such heaps of waste . After presenting it in the class room, implement it collectively for the welfare of the public. Be a model to society. 63 BIOLOGY Follow up Activities 1. Observe the figure. A B a. Label the parts termed A and B. b. What difference has occurred in the structure of A and B? c. How will this affect the function of the kidneys? 2. Given below is the last part of the pamphlet about kidney diseases, prepared by Sajin. Our health habits and life style, to a great extent, influence the health of the kidneys. And due to many reasons, the kidneys are damaged, sometimes even endangering life itself. By taking necessary precautions, the kidneys can be retained healthy to a certain extent. Suggest any four precautions and complete the pamphlet 3. Prepare 2 slogans for the awareness rally organized by the Environment Club of your school as part of the waste disposal scheme. 64