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Chapter 11.4: Meiosis How many chromosomes do humans have? Diploid: Haploid: What are homologous chromosomes? Meiosis: Remember: this is DIFFERENT from mitosis because mitosis results in 2 identical, diploid cells. Phases of Meiosis (PMAT) Interphase: DNA replication & cell growth (same as in mitosis) Chromosome count: Meiosis I: separation of homologous chromosomes • Prophase I: homologous chromosomes form a tetrad (crossing over occurs); nuclear membrane breaks down; centrioles separate • Metaphase I: homologous chromosomes line up side-by-side in the middle of the cell; spindles attach at centromere • Anaphase I: homologous chromosomes separate to opposite sides of the cell • Telophase I: nuclear membrane reforms & cell begins to separate into two. Cytokinesis: Cell separates into two diploid cells **No Interphase = No DNA Replication** Chromosomes Count: Meiosis II: separation of sister chromatids (very similar to mitosis) • Prophase II: nuclear membrane breaks down, centrioles separate • Metaphase II: chromosomes move to the middle of the cell (not side-by-side); spindles attach at centromere • Anaphase II: sister chromatids pulled apart by spindles; move to opposite sides of the cell • Telophase II: each cell begins to cleave into two cells Cytokinesis: Cell separates into 4 genetically different, haploid cells