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Cardiovascular: The Heart
Anatomy and Physiology
Heart Anatomy
mediastinum
Coverings of the Heart
pericardium
fibrous pericardium
serous pericardium
parietal layer
visceral layer (AKA epicardium)
pericardial cavity
Pericarditis - inflammation of the
pericardium
Layers of the Heart Wall
superficial epicardium
visceral layer of the serous pericardium
middle myocardium
made mostly of cardiac muscle and forms
the bulk of the heart
deep endocardium
sheet of endothelium on a connective
tissue layer
lines the heart chambers and covers the
connective tissue skeleton on the valves
fibrous skeleton
Chambers and Great Vessels
4 chambers
2 superior atria
2 inferior ventricles
intraventricular septum
atrioventricular groove (coronary sulcus)
anterior interventricular sulcus
posterior interventricular sulcus
Atria
auricle
pectinate muscles
fossa ovalis
superior vena cava
inferior vena cava
pulmonary veins
Ventricles
trabeculae carneae
papillary muscles
Pulmonary arteries
aorta
Pathway of Blood through the Heart
right side - pulmonary circuit
Superior and inferior vena cava
right atrium
Right atrioventricular valve
(tricuspid)
right ventricle
Right semilunar valve
(pulmonary SL)
Pulmonary arteries
Lung capillaries
Pathway of Blood through the Heart
Left side – systemic circuit
(stronger)
Pulmonary veins
left atrium
Left atrioventricular valve
(bicuspid, mitral)
left ventricle
Left semilunar valve (aortic SL)
Aorta
arteries
Capillaries
veins
Heart Valves
Atrioventricular (AV) Valves
atrio-ventricular junction
right AV valve
tricuspid valve
has three flexible flaps
left AV valve
bicuspid or mitral valve
has two flaps
Heart Valves
Semilunar (SL) Valves
aortic and pulmonary semilunar valves
valvular stenosis
Coronary Circulation
right and left
coronary arteries
atrioventricular
groove
cardiac veins
coronary sinus
Angina pectoris
Myocardial
Infarction
Cardiac Muscle
Striated and
interconnected
intercalated discs
Desmosomes
gap junctions
Autorhythmicity
Heart Physiology
Intrinsic Conduction System
non contractile cardiac cells
autorhythmic cells
autorhythmic cardiac cell locations
sinoatrial (SA) node
atrioventricular (AV) node
atrioventricular (AV) bundle (bindle of
His)
right and left bundle branches
ventricular walls as Purkinji fibers
Sequence of Excitation
sinoatrial (SA) node
usually generates an impulse about 75
times a minute
atrioventricular (AV) node
depolarization goes through gap junctions
in the atria to the AV node
part of the interatrial septum just above
the tricuspid valve
Sequence of Excitation
atrioventricular (AV) bundle (bundle of His)
inferior part of interatrial septum
right and left bundle branches
go along interventricular septum towards the apex
Purkinji fibers
ventricular contraction starts at the apex and
moves towards the atria
Sequence of Excitation
Arrhythmias
irregular heartrates
uncoordinated atrial and ventricular
contractions
Heartblock
pacemaker
Fibrillation
rapid, out-of-phase, irregular contractions
defective pacemaker (SA node)
ectopic focus
Extrinsic Innervation of the Heart
autonomic nervous system
sympathetic accelerates the rate and force
of the beats
parasympathetic slows the heart
Electrocardiography
electrocardiogram (EKG or ECG)
three deflection waves
P wave is first and small
depolarization of the SA node
QRS wave is large
ventricular polarization
T wave
ventricular repolarization
Electrocardiography
P-R (P-Q) interval
from the beginning of atrial excitation to
the beginning of ventricular excitation - about .16 s
Q-T interval
beginning of ventricular depolarization
through repolarization - .36s
enlarged R wave
enlarged ventricles
prolonged Q-T
abnormal repolarization
Cardiac Cycle Vocabulary
systole – contraction
diastole – relaxation
Mechanical Events of the Cardiac Cycle
ventricular filling - mid-to-late diastole
ventricular systole
Isovalumetric relaxation - early diastole
Heart Sounds
lub-dup
lub is closing of AV valves
dup is closing of SL valves
mitral before tricuspid - aortic SL before
pulmonary
Murmurs
unusual or abnormal heart sounds
incompetent valve
stenotic valve
Cardiac Output
product of heart rate and stroke volume
volume of blood being pumped out by a
ventricle with each beat
can easily be 5.25 liters a minute
Homeostatic Imbalances
Tachycardia
Bradycardia
Congestive Heart Failure
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