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Case Notification Request (CNR) Statement In order for a condition to be added to the list of Nationally Notifiable Conditions, a Case Notification Request (CNR) statement must be submitted along with the CSTE position statement template for placing diseases or conditions under national surveillance. The requirement is outlined in CSTE position statement 08-EC-02. Nationally Notifiable Condition: _Acute hepatitis C_________________ Date: _12/17_/2008__ CDC programmatic unit: _NCHHSTP/DVH/ESB_____________________ CDC staff completing form: _Monina Klevens_ Contact info: [email protected]__ (email) and 404-718-8506 (phone) Please check requested timeliness of case notification to CDC: ___ Immediate notification _X_ Standard notification ___ Both Immediate and Standard notification. Notification timeliness may be specific to sub-types of condition or circumstances associated with the event. Please Specify: ______________________________________________________________________________ Please check requested case notification to CDC by classification: __X_ Confirmed cases ___ Probable (presumptive) cases ___ Suspected (possible) cases ___ All cases prior to classification Instructions: For all conditions answer questions 1-6 below. In addition, for conditions requiring immediate notification (for either all or some of cases), answer questions 7-11. Yes No 1. Is there a law/rule requiring reporting for the condition in the majority of state and territorial X jurisdictions, or in a combination of state/territorial jurisdictions that taken together comprise 50% or more of the US population? (NCPHI staff can assist CDC Programs with the response to this question, if needed) 2. What purposes, goals, and objectives will be met by case notification to the national level? Hepatitis C virus (HCV) infection is the most common bloodborne infection in the United States. National recommendations for controlling HCV infection emphasize primary prevention, including screening and testing of blood donors, viral inactivation of plasma-derived products, risk reduction counseling and screening of persons at risk, and routine infection control practices in healthcare settings. Objectives of notification of acute hepatitis C cases which represent recent infections include: To identify outbreaks of disease, which are followed by investigations to determine the source of transmission and control and prevention of additional cases. Recent outbreaks of healthcare associated transmission illustrate the importance of following up on reports of cases of acute hepatitis C. To counsel cases about prevention of secondary transmission to contacts. To characterize groups at risk and target prevention activities accordingly. To monitor trends in disease incidence and risk factors for infection, which is useful to assess the effectiveness of prevention. 3. How will the cumulative or aggregate case data be used, including both standard periodic analyses of nationally-compiled data and anticipated ad-hoc analyses? Case reports of acute hepatitis C are analyzed weekly internally, and clusters are confirmed with state health departments. Reports of hepatitis C are summarized annually in the MMWR. Also, an extensive analysis of data is conducted for publication annually as a MMWR Surveillance Summary, along with case reports of acute hepatitis A and B. 4. How frequently will information be provided to states and territories regarding the results of analyses of the compiled case data? At minimum, all states receive a quarterly report of cases, as well as the annual MMWR and the MMWR surveillance summary for acute viral hepatitis. 5. What is the anticipated schedule of release of published data based on case notifications, as well as any rules for restrictions on the printing of counts of case data? Acute Hep C_CNRCSTE Case Notification Request (CNR) acute HCV.doc Publication of data will follow this schedule (at a minimum): Quarterly feedback to state health departments Annually in the MMWR annual report of notifiable diseases. Annually in the MMWR surveillance summary of acute viral hepatitis. 6. What is the anticipated plan for the re-release of case data, including re-release to WHO or other parties? There is no current plan to re-release case data. Aggregate reports are publicly available, and states maintain confidential surveillance databases. Conditions Requiring Immediate Notification 7. Does this condition have special importance for the international health regulations [i.e., a public health event that may constitute a "public health emergency of international concern" as defined in IHR 2005 including, but not limited to: smallpox, novel influenza, wild-type polio, Severe Acute Respiratory Syndrome (SARS)]? 8. Is this condition included on the list of Category A possible bioterrorism agents and toxins? 9. Has this condition or disease been declared eliminated (absence of endemic disease transmission) in the United States or eradicated globally? 10. Why is immediate case notification to the national level necessary? 11. How will CDC respond to the case notification? Acute Hep C_CNRCSTE Case Notification Request (CNR) acute HCV.doc Yes No