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Turk A&P reproduction growth and development mobilization of body defenses maintenance of electrolytes, water, and nutrient balance regulation of cellular metabolism and energy endocrine pituitary, thyroid, parathyroid, adrenal, pineal, and thymus exocrine small intestine, stomach, kidneys, and heart Endocrine Gland Stimuli humoral stimuli Neural stimuli Hormonal stimuli Nervous System Modulation spenoid bone infundibulum connects it to the hypothalamus Posterior lobe Neurohormones oxcytosin antidiuretic hormone anterior lobe – adenohypophysis TSH, ACTH, FSH, and LH GH and PRL stimulates uptake of amino acids stimulates uptake of sulfur mobilizes fats decreases glucose uptake and metabolism growth hormone-releasing hormone (GHRH) growth hormone-inhibiting hormone (GHIH) chondroitin sulfate Somatostatin Gigantism Acromegaly progeris pituitary dwarfism thyrotropin thyrotropin-releasing hormone (TRH) somatostatin corticotropin Adenohypophysis Adrenal cortex corticosteroid hormones glucocorticoids corticotropin-releasing hormone (CRH) Follicle-stimulating hormone (FSH) Stimulates gamete production Luteinizing hormone (LH) Promotes production of gonadal hormones estrogens and progesterone Testosterone gonadotropin-releasing hormone (GnRH) Lactotropes prolactin-inhibiting hormone (PIH) oxytocin paraventricular nuclei antidiuretic hormone supraoptic nucleus diabetes insipidus Isthmus Thyroglobulin Colloid parafollicular cells Calcitonin antagonist to the parathyroid hormone lowers blood calcium levels inhibits osteoclast activity stimulates calcium uptake and incorporation into bone thyroxine (T4) Triiodothyronine (T3) thyroxin-binding globulin (TBG) thyroxine thyroid-stimulating hormone (TSH) thyrotropin-releasing hormone (TRH) hypothyroid disorders Myxedema endemic goiter Cretinism Graves disease oxyphil cells chief cells (principle cells) parathyroid hormone (PTH) or parathormone skeleton osteoclasts kidneys intestine Hyperparathyroidism hypoparathyroidism inner adrenal medulla epinephrine and norepinephrine outer adrenal cortex aldosterone renin-angiotensin mechanism Sodium and potassium ions ACTH Atrial natriuretic peptide (ANP) cortisol (hydrocortisone) gonadocorticoids - adrenal sex hormones Cushing’s disease Addison’s disease acinar cells Pancreatic juice pancreatic islets Alpha and beta cells Glucagon and insulin Diabetes mellitus Ketoacidosis polyuria polydipsia Polyphagia Hypoglycemia delta cells somatostatin ovaries testes progesterone Estrogen testosterone gonadotropins pinealocytes melatonin thymopoietins thymosins T lymphocytes Heart gastrointestinal tract enteroendocrine cells placenta kidney atrial natriuretic peptide erythropoietin skin cholecalciferol