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MITOSIS AND MEIOSIS: SOME DEFINITIONS Haploid: A cell containing a single set (n) of chromosomes. May be the natural state of the organism or a gamete of a diploid organism. Diploid: A cell containing two sets (2n) of chromosomes (one from each parent). Chromatids: Identical daughter chromosomes resulting after duplication and are joined at the centromere (also called sister chromatids). Homologous chromosomes: Chromosomes that code for the same genes but come from different parents (also called non-sister chromatids). Crossing over: Occurs in Meiosis I. Involves swapping of DNA fragments between homologous chromosomes. Produces chromosomes with different allelic complements. Mitosis: Needed for growth, repair, and development in multicellular organisms. Yields two daughter cells that are identical (barring mutation) to the parental cell in allelic complement and chromosome number, n. Referred to as a mechanism of constancy. - Sequence – Figure 12.5 page #218. Meiosis: Needed for gamete cell formation in sexual organisms. Involves two rounds of cell division, Meiosis I (reduction division) and Meiosis II (analogous to Mitosis). Yields cells that have half the number of chromosomes and different gene combinations (because of crossing over) when compared to parental cell. Referred to as a mechanism of diversity. - Sequence – Figure 13.7 page #240. Table 1: A brief comparison of mitosis and meiosis. Interphase (I) Prophase (I) Metaphase (I) Anaphase (I) Telophase (I) Cytokinesis Prophase (II) Metaphase (II) Anaphase (II) Telophase (II) Cytokinesis - Meiosis chromosomes, centrosomes duplicate chromosomes condense centrosomes - opposite ends of cell homologous chromosomes pair - form tetrads nuclear membrane disappears crossing over occurs tetrads line up at equator homologous chromosomes pulled apart nuclear membranes appear two haploid (n) cells are formed - chromosomes are still doubled no replication is required chromosomes condense centrosomes - opposite ends of cell nuclear membranes in both cells disappear chromosomes line up at equator chromatids pulled apart nuclear membranes appear four haploid (n) cells are formed each is different if crossing over occurs - two pairs of identical cells If not - meiosis is complete - - Mitosis chromosomes, centrosomes duplicate chromosomes condense centrosomes - opposite ends of cell nuclear membrane disappears chromosomes line up at equator chromatids pulled apart nuclear membranes appear two diploid (2n) cells are formed - identical to parent cell - mitosis is complete