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Lecture 12 - DNA, DNA Replication and Transcription Fill in the blank : fill in the blanks on the right with the correct word from the list on the left. Some words can be used more then once. 1. ___________ bonds make up the backbone of DNA 2. ________ and _________ are the two types of nucleic acids found in the human body 3. RNA is a ________ molecule 4. ______ are the bases found in RNA 5. ______ are the bases found in DNA 6. deoxyribose is found in ______ 7. DNA is a _______ molecule 8. ______________ bonds are what hold complementary nitrogenous bases together in DNA 9. DNA strands orientations run from ________ to _________ 10.The ____________ of replication is where DNA replication begins 11.DNA is a ________________ helix • • • • • • • • • • • • • • ss covalent A,U, G, C ds nucleotides 3’ ribose double origin DNA hydrogen T, A, C, G RNA 5’ 12. Watson and Crick deduced the structure of the molecule ________ 13. _____________ are the polymers of DNA and RNA True/ False: circle T or F for the given statements 1. T/F The character of the nucleotide is defined by its nitrogenous base 2. T/F A and G are purines and C and T pyrimidines 3. T/F Humans do not eat “genes” 4. T/F DNA is single helix 5. T/F The DNA sequence A-T-G-C-G-G-T-A would have a complementary strand of ! T-A-C-G-C-G-T-A 6. T/F DNA replication is semiconservative 7. T/F Genome is a segment of DNA 8. T/F There are approximately 24, 000 genes 9. T/F DNA can leave the nucleus to make a protein 10.T/F DNA can be made by body 11.T/F When the parent cell divides, only one daughter cell gets a copy of the original DNA 12. T/F Nucleotides are stored in the nucleus ! 1 Lecture 12 - DNA, DNA Replication and Transcription Multiple Choice : circle the correct answer 1. An RNA or DNA molecule is a polymer made of subunits called a. bases b. amino acids c. nucleic acids d. pyrimidines 2. The information carried by a DNA molecule is in a. its amino acids b. the sugars and phosphates forming the backbone c. the order of the bases in the molecule d. the total number of nucleotides it contains e. the RNA units that make up the molecule 3. A gene is a. the same thing as a chromosome b. the information for making a polypeptide c. made of RNA d. made of protein 4. Which of the following is NOT needed for DNA replication? a. ribosomes b. DNA c. nucleotides d. enzymes e. all of the above 5. How many letters do you have in the “genetic” alphabet? a. 1 b. 6 c. 20 d. 4 e. 3 6. _________ is analogous to the recipes of a cook book a. DNA b. amino acids c. genes d. RNA 7. DNA replication occurs inside the ________ and translation occurs inside the _______ ! 2 Lecture 12 - DNA, DNA Replication and Transcription a. cytoplasm; cytoplasm b. nucleus; cytoplasm c. DNA; ribosomes d. cytoplasm; nucleus 8. Genotype is expressed as a a. gene b. genome c. skin d. protein e. all of the above Short Answer 1. Draw the central dogma occurring within an eukaryotic cell, include all steps and what is occurring 2. How do we make a gene “visible” ? 3. Explain what is occurring in the three steps of transcription (i.e. initiation, elongation, termination) ! 3