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Download Table Breed predisposition and heritability 2010 - Acapulco-Vet
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TABLE : BREED PREDISPOSITION AND HERITABILITY FOR CONGENITAL AND ACQUIRED CARDIAC DISEASE IN CATS AND DOGS (UPDATED JANUARY 2010) BREED INCREASED RISK HERITABILITY All breeds Airedale Akita American shorthair cat PDA PS VSD HCM Bichon frise Basset Beagle Bordeaux Dog PDA VSD PS SAS TD Bouvier Boxer SAS SAS PS ASD ARVC British short hair cat HCM Bull terrier Burmese cats CKCS Chihuahua Cocker Spaniel Cocker Spaniel (English) Collie Cornish Rex Dalmatian Dachshund Deerhound MD SAS Atrial standstill PDA MVE PDA PS PDA PS SSS DCM PDA HCM AV dysplasia DCM MVE DCM Doberman ASD DCM English Bulldog PS TOF VSD English Springer spaniel SAS ARVC PDA VSD proven, polygenic threshold trait proven, polygenic threshold trait unknown autosomal dominant possibly modified by modifier genes or by environmental triggers proven, polygenic threshold trait unknown proven, polygenic threshold trait strongly suspected strongly suspected strongly suspected strongly suspected proven, polygenic threshold trait unknown autosomal dominant trait one mutation recognised autosomal dominant possibly modified by modifier genes or by environmental triggers strongly suspected strongly suspected suspected proven, polygenic threshold trait proven, polygenic threshold trait proven, polygenic threshold trait proven, polygenic threshold trait proven, polygenic threshold trait proven, polygenic threshold trait unknown hereditary, pattern unknown proven, polygenic threshold trait autosomal dominant possibly modified by modifier genes or by environmental triggers unknown suspected hereditary proven, polygenic threshold trait familial or genetic basis suspected unknown suspected autosomal dominant with reduced penetrance proven, polygenic threshold trait strongly suspected autosomal recessive with variable expression strongly suspected Strongly suspected proven, polygenic threshold trait proven German Shepherd dog PDA SAS MD TD PRAA DCM German Short Hair Pointer Golden Retriever SAS SAS MD TD DCM Great Dane MD TD AS PRAA DCM Great Pyrenees Greyhound Irish Setter TD PRAA PRAA Irish Wolfhound TD DCM IAF Keeshond TOF VSD Labrador retriever PDA PS TD PDA DCM WPW Lakeland Terrier Maine Coon VSD PPDH HCM Maltese Mastiff PDA MD PS proven, polygenic threshold trait strongly suspected strongly suspected strongly suspected strongly suspected, complex inheritance familial or genetic basis suspected strongly suspected proven strongly suspected proven Study 1: single recessive allele with a substantial impact on the expression of TVD Study 2: an autosomal dominant trait with reduced penetrance. chromosome 9 mutation familial or genetic basis suspected strongly suspected strongly suspected strongly suspected strongly suspected, complex inheritance X-linked recessive trait suspected strongly suspected Strongly suspected strongly suspected, complex inheritance unknown suspected autosomal dominant unknown, association with DCM suspected autosomal recessive autosomal recessive with variable expression proven, polygenic threshold trait proven, polygenic threshold trait proven recessive proven, polygenic threshold trait familial or genetic basis suspected Proven recessive if in association with TD unknown unknown autosomal dominant possibly modified by modifier genes or by environmental triggers Myosin binding protein C mutation proven, polygenic threshold trait strongly suspected polygenic threshold Newfoundland SAS MD PDA DCM IAF Norwegian Forest Cat HCM OESD TD DCM Persian cats Poodle Pomeranian Portuguese water dog Pugs Rottweiler Samoyed AV canal defect HCM Moderator band CM PDA PDA DCM Sheltie Shih tzu Sint Bernard PS AS PS AS ASD PS PDA SSS PDA VSD DCM Ragdoll cat HCM Sphynx HCM Terriers Weimaraner PS TD PPDH DCM Welsh Corgi WHWT PDA PS VSD TOF SSS PDA Schnauzer Yorkshire Terrier autosomal dominant with variable expression strongly suspected proven, polygenic threshold trait suspected autosomal dominant unknown, association with DCM suspected autosomal dominant possibly modified by modifier genes or by environmental triggers strongly suspected familial or genetic basis suspected proven autosomal dominant possibly modified by modifier genes or by environmental triggers suspected proven, polygenic threshold trait proven, polygenic threshold trait proven, autosomal recessive trait proven, polygenic threshold trait proven proven, polygenic threshold trait strongly suspected unknown proven, polygenic threshold trait proven, polygenic threshold trait unknown proven, polygenic threshold trait unknown familial or genetic basis suspected autosomal dominant possibly modified by modifier genes or by environmental triggers Myosin binding protein C mutation autosomal dominant possibly modified by modifier genes or by environmental triggers proven, polygenic threshold trait strongly suspected unknown familial or genetic basis suspected proven, polygenic threshold trait polygenic threshold strongly suspected strongly suspected unknown proven, polygenic threshold trait
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