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CURRICULUM VITAE
DATE PREPARED: January 12, 2009
PART I: General Information
Name:
JOHN ISAAC LOEWENSTEIN
Education:
1969
1973
B.S., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
M.D., SUNY, BUFFALO
Postdoctoral Training:
01/73-12/74 Intern in Medicine, Medicine, Washington Hospital Center
01/74-12/77 Resident in Ophthalmology, Ophthalmology, Boston University
Affiliated Hospitals
01/77-12/79 Fellow in Retina, Retina, Boston University Affiliated Hospitals
01/77-12/79 Research Fellow, Retina, Boston University Medical School
Licensure and Certification:
1974
1978
Massachusetts Registered Physician
Diplomate, American Board of Ophthalmology
Academic Appointments:
1977-1979
1980-1983
1983-1984
1986-1994
1994-1999
1999-2005
20062008-
Instructor in Ophthalmology, Boston University Medical School,
Boston, MA
Assistant Professor of Ophthalmology, Boston University Medical
School, Boston, MA
Associate Professor of Ophthalmology, Boston University Medical
School, Boston, MA
Clinical Instructor in Ophthalmology, Harvard Medical School, Boston,
MA
Instructor in Ophthalmology, Harvard Medical School, Boston, MA
Assistant Professor of Ophthalmology, Harvard Medical School,
Boston, MA
Associate Professor of Ophthalmology, Harvard Medical School
Vice Chair for Education, Department of Ophthalmology, Harvard
Medical School, Boston, MA
Hospital or Affiliated Institution Appointments:
01/77-12/79 Assistant in Ophthalmology, University Hospital, Boston, MA
01/78-12/84 Assistant Director of Ophthalmology, Boston City Hospital, Boston,
MA
01/79-12/89 Assistant Visiting Surgeon in Ophthalmology, University Hospital,
Boston, MA
01/84-12/85 Director of Ophthalmology, Boston City Hospital, Boston, MA
01/84-12/90 Assistant in Ophthalmology, Massachusetts Eye and Ear Infirmary,
Boston, MA
01/91-12/95 Assistant Surgeon, Massachusetts Eye and Ear Infirmary, Boston, MA
01/96Surgeon, Massachusetts Eye and Ear Infirmary, Boston, MA
Hospital and Health Care Organization Clinical Service Responsibilities:
1978-1984
1985-
Attending Physician, Retina Service, University Hospital
Attending Physician, Retina Service, Massachusetts Eye and Ear
Infirmary
Major Administrative Responsibilities:
1994-2008
1996-1997
1997-1998
1997-2003
1997-2003
20022008-
Associate Chief of Ophthalmology for Managed Care, Massachusetts
Eye and Ear Infirmary
President, Ophthalmology Staff, Massachusetts Eye and Ear Infirmary
President, Medical Staff, Massachusetts Eye and Ear Infirmary
Board Member, Eye Care Excellence Network
Co-Medical Director, Eye Care Excellence Network
Director of Residency Training in Ophthalmology, Massachusetts Eye
and Ear Infirmary
Associate Chief of Ophthalmology for Clinical Affairs, Massachusetts
Eye and Ear Infirmary
Major Committee Assignments:
HMS / HSDM
2005-
Harvard Residency Managing Committee [Chairperson], Harvard
Medical School
2007Practice Advisory Committee, Massachusetts Eye and Ear Infirmary
Affiliated Inst
1988-1992
1989-2001
19911994-2004
Social Service Advisory Committee, Massachusetts Eye and Ear
Infirmary
Quality Assurance Committee, Massachusetts Eye and Ear Infirmary
Fellowship Committee, Massachusetts Eye and Ear Infirmary
Eye Utilization Review Committee [Chairperson], Massachusetts Eye
19961996-1997
200220022005-2006
2006-2007
2007-2008
and Ear Infirmary
Board of Surgeons, Massachusetts Eye and Ear Infirmary
Eye Service Executive Committee, Massachusetts Eye and Ear
Infirmary
Residency Selection Committee [Chairperson], Massachusetts Eye and
Ear Infirmary
Residency Steering Committee [Chairperson], Massachusetts Eye and
Ear Infirmary
Vision Rehabilitation Search Committee [Chairperson], Massachusetts
Eye and Ear Infirmary
Oculoplastics Search Committee [Chairperson], Massachusetts Eye and
Ear Infirmary
Eye Service Executive Committee, Massachusetts Eye and Ear
Infirmary
Professional Societies:
19761978197819801999-
Massachusetts Society of Eye Physicians and Surgeons, Member
(Executive Board 1986-9)
Association for Research in Vision and Ophthalmology, Member
New England Ophthalmologic Society, Member (Program Committee,
1979)
American Academy of Ophthalmology, Member
Retina Society, Member
Editorial Boards:
1986199520012001200220042004-
Ad-Hoc Reviewer, Journal of the American Medical Association
Member, Digital Journal of Ophthalmology
Ad-Hoc Reviewer, Proceedings of the National Academy of Sciences
Ad-Hoc Reviewer, Ophthalmic Surgery and Lasers
Ad-Hoc Reviewer, New England Journal of Medicine
Ad-Hoc Reviewer, American Journal of Ophthalmology
Ad-Hoc Reviewer, Documenta Ophthalmologica
Awards and Honors:
1996
1998
2001
2004
2007
Teacher of the Year Award, Massachusetts Eye and Ear Infirmary
Distinguished Service Award, Massachusetts Eye and Ear Infirmary
Teacher of the Year Award, Massachusetts Eye and Ear Infirmary
Scholar, Academy , Harvard Medical School
Nominee, Harvard Medical School Prize for Excellence in Teaching
(Years 3&4), Harvard Medical School
Part II: Bibliography
Original Articles
1. Loewenstein JI, Lessell S. Experimental cryosurgical lesion of the optic nerve.
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1980;215(2):97-103.
2. Green GJ, Lessell S, Loewenstein JI. Ischemic optic neuropathy in chronic
papilledema. Arch Ophthalmol. 1980;98(3):502-4.
3. Leibowitz HM, Krueger DE, Maunder LR, Milton RC, Kini MM, Kahn HA,
Nickerson RJ, Pool J, Colton TL, Ganley JP, Loewenstein JI, Dawber TR. The
Framingham Eye Study monograph: An ophthalmological and epidemiological
study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual
acuity in a general population of 2631 adults, 1973-1975. Surv Ophthalmol.
1980;24(Suppl):335-610.
4. Lubin JR, Loewenstein JI, Frederick AR. Vogt-Koyanagi-Harada syndrome with
focal neurologic signs. Am J Ophthalmol. 1981;91(3):332-41.
5. Loewenstein J. Abnormal Visual Phenomona. Clinical Experience. 1984;1:12-21.
6. Loewenstein JI, Palmberg PF, Connett JE, Wentworth DN. Effectiveness of a
pinhole method for visual acuity screening. Arch Ophthalmol. 1985;103(2):222-3.
7. Loewenstein JI. Visual hallucinations in patients with choroidal neovascularization.
JAMA. 1994;272(3):243.
8. Loewenstein JI. Bilateral macular holes in von Hippel-Lindau disease. Arch
Ophthalmol. 1995;113(2):143-4.
9. Loewenstein JI, Hogan RN, Jakobiec FA. Osseous metaplasia in a preretinal
membrane. Arch Ophthalmol. 1997;115(1):117-9.
10. Loewenstein JI. Clinical practice guidelines. Int Ophthalmol Clin. 1998;38(3):75-85.
11. Loewenstein JI. Introduction to capitation. Int Ophthalmol Clin. 1998;38(3):101-6.
12. Loewenstein JI. Overview of quality measurement and improvement. Int
Ophthalmol Clin. 1998;38(3):59-68.
13. Kim RY, Loewenstein JI. Systemic diseases manifesting as exudative retinal
detachment. Int Ophthalmol Clin. 1998;38(1):177-95.
14. Harris EW, Loewenstein JI, Azar D. Vitamin A deficiency and its effects on the eye.
Int Ophthalmol Clin. 1998;38(1):155-61.
15. Zacks DN, Samson CM, Loewenstein J, Foster CS. Electroretinograms as an
indicator of disease activity in birdshot retinochoroidopathy. Graefes Arch Clin Exp
Ophthalmol. 2002;240(8):601-7.
16. EyeTech Study Group. Anti-vascular endothelial growth factor therapy for
subfoveal choroidal neovascularization secondary to age-related macular
degeneration. Ophthalmology. 2003;240:601-7.
17. Ray S, Loewenstein J. Atypical manifestation of multiple evanescent white dot
syndrome with large peripapillary lesion. Arch Ophthalmol. 2003;121(12):1794-6.
18. Rizzo JF, Wyatt J, Loewenstein J, Kelly S, Shire D. Methods and perceptual
thresholds for short-term electrical stimulation of human retina with microelectrode
arrays. Invest Ophthalmol Vis Sci. 2003;44(12):5355-61.
19. Rizzo JF, Wyatt J, Loewenstein J, Kelly S, Shire D. Perceptual efficacy of electrical
stimulation of human retina with a microelectrode array during short-term surgical
trials. Invest Ophthalmol Vis Sci. 2003;44(12):5362-9.
20. Husain D, Loewenstein JI. Surgical approaches to retinal prosthesis implantation. Int
Ophthalmol Clin. 2004;44(1):105-11.
21. Loewenstein JI, Montezuma SR, Rizzo JF. Outer retinal degeneration: an electronic
retinal prosthesis as a treatment strategy. Arch Ophthalmol. 2004;122(4):587-96.
22. Ray S, Friberg TA, Beatty RR, Loewenstein J. Late posterior migration of glass
intraocular foreign bodies. Arch Ophthalmol. 2004;122(6):923-6.
23. Hatton MP, Loewenstein J. Attrition from ophthalmology residency programs. Am J
Ophthalmol. 2004;138(5):863-4.
24. Lee MS, Gupta N, Penson RT, Loewenstein J, Wepner MS, Seiden MV, Milam AH.
Cone damage in patients receiving high-dose irofulven treatment. Arch Ophthalmol.
2005;123(1):29-34.
25. Durand ML, Kim IK, D'Amico DJ, Loewenstein JI, Tobin EH, Kieval SJ, Martin
SS, Azar DT, Miller FS, Lujan BJ, Miller JW. Successful treatment of Fusarium
endophthalmitis with voriconazole and Aspergillus endophthalmitis with
voriconazole plus caspofungin. Am J Ophthalmol. 2005;140(3):552-4.
26. Krzystolik MG, Filippopoulos T, Ducharme JF, Loewenstein JI. Pegaptanib as an
adjunctive treatment for complicated neovascular diabetic retinopathy. Arch
Ophthalmol. 2006;124(6):920-1.
27. Henderson BA, Neaman A, Kim BH, Loewenstein J. Virtual training tool.
Ophthalmology. 2006;113(6):1058-9.
28. Ament CS, Zacks DN, Lane AM, Krzystolik M, D'Amico DJ, Mukai S, Young LH,
Loewenstein J, Arroyo J, Miller JW. Predictors of visual outcome and choroidal
neovascular membrane formation after traumatic choroidal rupture. Arch
Ophthalmol. 2006;124(7):957-66.
29. Montezuma SR, Loewenstein J, Scholz C, Rizzo JF. Biocompatibility of materials
implanted into the subretinal space of yucatan pigs. Invest Ophthalmol Vis Sci.
2006;47(8):3514-22.
30. Warden SM, Pachydaki SI, Christoforidis JB, D'Amico DJ, Loewenstein JI.
Choroidal neovascularization after epiretinal membrane removal. Arch Ophthalmol.
2006;124(11):1652-4.
31. Andreoli CM, Husain D, Davis TS, Loewenstein JI. Chorioretinal changes heralding
metastatic malignancy. Arch Ophthalmol. 2006;124(12):1790-2.
32. Ho J, Loewenstein JI. Endophthalmitis associated with intravitreal injections. Int
Ophthalmol Clin. 2007;47(2):199-208.
33. Singh RP, Hatton M, Sprich S, Loewenstein J. Posttraumatic stress. Ophthalmology.
2007;114(6):1238.
34. Ahmed E, Loewenstein J. Leber congenital amaurosis: disease, genetics and therapy.
Semin Ophthalmol. 2008;23(1):39-43.
35. de Bruin DM, Burnes D, Loewenstein J, Chen Y, Chang S, Chen T, Esmaili D, de
Boer JF. In-vivo three-dimensional imaging of neovascular age related macular
degeneration using optical frequency domain imaging at 1050 nm. Invest
Ophthalmol Vis Sci. 2008.
Reviews/Chapters/Editorials
1. Loewenstein J. Vitrectomy. In: Snow JC Ed. Anesthesia in Otolaryngology and
Ophthalmology. New York: Appleton Century Crofts;1982.
2. Loewenstein J, Putnoi D. Common Ocular Problems. In: Noble J, ed. Textbook of
General Medicine and Primary Care. Boston/Toronto: Little, Brown;1987. p. 705722.
3. Loewenstein J. Eye Emergencies. In: Noble J, ed. Textbook of General Medicine
and Primary Care. Boston/Toronto: Little, Brown;1987. p. 689-703.
4. Loewenstein J. The Eye in Systemic Disease. In: Noble J, ed. Textbook of General
Medicine and Primary Care. Boston/Toronto: Little, Brown;1987. p. 737-743.
5. Loewenstein J. The Ocular Examination. In: Noble J, ed. Textbook of General
Medicine and Primary Care. Boston/Toronto: Little, Brown;1987. p. 683-687.
6. Rizzo JF, Loewenstein J, Wyatt J. Development of an Epiretinal Electronic Visual
Prosthesis. In: Hollyfield JG, ANderson RE, LaVail MM, eds. Retinal Degenerative
Diseases and Experimental Therapy. New York: Plenum Publishers;1999. p. 463469.
7. Loewenstein J. Retinopathy associated with blood anomalies. In: Albert D, Jakobiec
F, editors. Principles and Practice of Ophthalmology. Philadelphia: W.B.
Saunders;1999.
8. Friedman D Loewenstein J. Strategies for improving the physician-patient
relationship. In: Albert D, Jakobiec F. Principles and Practice of Ophthalmology.
Philadelphia: W.B. Saunders;1999.
9. Reddy HS, Loewenstein JI. Visual Function. In: Loewenstein JI and Lee S, eds.
Ophthalmology: Just the Facts. New York: McGraw-Hill;2003.
10. Loewenstein JI. Vitreous, Retina, and Choroid. In: Loewenstein JI and Lee S, eds.
Ophthalmology: Just the Facts. New York: McGraw-Hill;2003.
11. Loewenstein JI, Warden SM, Rizzo JF. Visual Prostheses. In: Hartnett ME, ed.
Pediatric Retinal Disease: Medical and Surgical Approaches. Philadelphia:
Lippincott Williams and Wilkins;2004.
Books, Monographs, and Textbooks
1. Loewenstein J, editor, section on ophthalmology; In Noble J, editor. Textbook of
General Medicine and Primary Care. Boston: Little, Brown;1987. p. 683-743.
2. Loewenstein J, editor. Managed Care. In: International Ophthalmology Clinics.
Volume 38 Philadelphia: Lippincott-Raven;1998.
3. Loewenstein JI and Lee S, editors. Ophthalmology: Just the Facts. New York:
McGraw-Hill;2003.
Abstracts
1. Shahin ME, Rizzo JF, Wyatt J, Loewenstein J. Evaluation of external electrical
stimulation studies. Inv Ophthalmol Vis Sci Suppl. 2000;40:S860.
2. Loewenstein JI, Rizzo JF, Montezuma SR. Implantation of subretinal polyimide in
Yucatan pigs. . Inv ophthalmol Vis Sci Suppl. 2002;43:S178.
3. Shire DB, Rizzo JF, Loewenstein JI. Micromachined tacks to attach a prosthesis to
the retina. . Inv Ophthalmol Vis Sci Suppl. 2002;43:S179.
4. Ament CS, Zacks D, Lane AM, D’Amico DJ, Young L, Mukai S, Loewenstein
J,Gragoudas E, Arroyo J, Miller J . Traumatic choroidal rupture: visual outcome and
treatment of choroidal vascular membranes. . Inv. Ophthalmol. Vis Sci Suppl. .
2002;43:S179.
5. Shire DB, Gingerich M, Theogarajan L, Wyatt J, Loewenstein J, Montezuma S,
Rizzo J. Packaging development for retinal prosthesis. Inv. Ophthalmol. Vis Sci
Suppl. 2003;44:S210.
6. Lee MS, Gupta N, Loewenstein JI, Wepner M, Milam AM. Retinal cone toxicity in
an ovarian cancer patient treated with Irofulven. Inv. Ophthalmol. Vis Sci Suppl.
2003;44:S21.
7. Rizzo JF, Jensen RJ, Loewenstein J, Wyatt J. Unexpectedly small percepts evoked
by epi-retinal electrical stimulation in blind humans. Inv. Ophthalmol. Vis Sci
Suppl. . 2003;44:S174.
8. Iaccheri B, Fiore T, Androudi S, Papadaki T, Loewenstein JI, Miller JW, Young
LHY, D’Amico D, Foster CS. Acute posterior multifocal placoid pigment
epitheliopathy (APMPPE): final outcome and visual prognosis. Inv. Ophthalmol.
Vis. Sci. Suppl. 2004;45:2692.
9. Montezuma SR, Loewenstein J, Scholz C, Rizzo JF. Biocompatibility of subretinal
materials in Yucatan pigs. Inv. Ophthalmol. Vis Sci Suppl. 2004;45:4169.
10. Rizzo JF, Wyatt JL, Loewenstein J, Montezuma S, Shire DB, Theogarajan L, Kelly
SK. Development of a wireless, ab externo retinal prosthesis. Inv. Ophthalmol. Vis
Sci Suppl. 2004;45:45.
11. Reddy HS, Loewenstein JI, Lane A, Shen L. Peripapillary choroidal
neovascularization. Inv. Ophthalmol. Vis Sci Suppl. 2004;45:3077.
12. Sun JK, Montezuma SR, Loewenstein J, Rizzo JF. Progress toward a minimally
invasive ab externo technique for subretinal prosthetic implantation. Inv.
Ophthalmol. Vis Sci Suppl. 2004;45:4190.
13. J. Chen, J. Loewenstein, H.A. Shah, C.D. Herbert, J.F. Rizzo. Extraction of a
Chronically Implanted Sub-Retinal Electrode Array. Inv Ophthalmol Vis Sci Suppl.
2005;46:1488.
14. R. Singh, M. Hatton, S. Sprich, J. Loewenstein. Post Traumatic Stress Disorder and
Depressive Symptoms After Open Globe Injuries. Inv Ophthalmol Vis Sci Suppl.
2005;46:5031.
15. M.D. Gingerich, D.B. Shire, J. Chen, J. Loewenstein, H.A. Shah, J. Sun, J.L. Wyatt,
J.F. Rizzo. Surgical Guides for Electrode Implantation Into the Subretinal Space. Inv
Ophthalmol Vis Sci Suppl. 2005;46:1494.
16. T. Fillippopoulos, J.F. Ducharme, J.I. Loewenstein, M.G. Krzytolik. Antiangiogenic
Agents as an Adjunctive Treatment for Complicated Neovascular Glaucoma. Inv
Ophthalmol Vis Sci Suppl. 2006;47:4476.
17. S.Chang, J.F. de Boer, M. de Bruin, A. Yun, D. Burns. Optical Frequency Domain
Imaging: High Speed OCT at 1050 nm to Image Choroidal Neovascularization in
Age-Related Macular Degereation Patients. Inv Ophthalmol Vis Sci Suppl.
2007;48:135.
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