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Transcript 
INTRODUCTION TO
IMMUNOLOGY
Janoš Terzić
Immunology
•  Latin immunitas - exemption from civic
duties and legal prosecution offered to
Roman senators
•  Immunolgy - experimental science in
which explanation of immunological
phenomena are based on experimental
observations
R. Koch, 1880. Infectious diseases
caused by microorganisms
L. Paster, 1880. rabies and cholera
vaccination
E. Methchnikoff, 1883.
phagocytosis
E. von Behring i S. Kitasato, 1890.
“antibodies”
EDWARD JENNER, 1796
Cowpox protects from smallpox
Lat. vaccinus = cow
1979. WHO smallpox eradicated
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© 2005 Elsevier
FUNCTIONS OF IMMUNE SYSTEM
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© 2005 Elsevier
IMMUNE SYSTEM
•  ADAPTIVE – INATE
specific – nonspecific
•  HUMORAL – CELL MEDIATED
•  ACTIVE – PASIVE
•  PRIMARY – SECONDARY
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© 2005 Elsevier
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© 2005 Elsevier
Downloaded from: StudentConsult (on 6 January 2013 09:46 AM)
© 2005 Elsevier
IMMUNOLOGY
•  ADAPTIVE – INATE
specific – nonspecific
•  HUMORAL – CELL MEDIATED
•  ACTIVE – PASIVE
•  PRIMARY – SECONDARY
CLONAL SELECTION
ANTIGEN RECEPTORS
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© 2005 Elsevier
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© 2005 Elsevier
ANTIBODIES
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© 2005 Elsevier
CELLS OF THE IMMUNE
SYSTEM
LYMPHOCYTES
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© 2005 Elsevier
DENDRITIC CELLS
MACROPHAGES
TISSUES OF THE IMMUNE
SYSTEM
Bursa of Fabricius
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© 2005 Elsevier
BONE MARROW
THYMUS
LYMPH NODE
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SPLEEN
SKIN
GUT
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© 2005 Elsevier
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