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Welcome to the invisible world of microbiology The World of Microbiology: Mastering the invisible, invincible, treatable and preventable Early life-forms The Beginning of Microbiology Anton van Leeuwenhoek (1674) Animalcules Louis Pasteur (1857) Golden age of microbiology Spontaneous generation controversy Robert Koch Koch’s postulates Anton van Leeuwenhoek The Beginning of Microbiology Anton van Leeuwenhoek (1674) Animalcules Louis Pasteur (1857) Golden age of microbiology Spontaneous generation controversy Robert Koch Koch’s postulates Louis Pasteur The Beginning of Microbiology Anton van Leeuwenhoek (1674) Animalcules Louis Pasteur (1857) Golden age of microbiology Spontaneous generation controversy Robert Koch Koch’s postulates Robert Koch What are bacteria? Typical Bacterial Cell Why can’t we see them with the naked eye? Because they are very, very small Rod 2mm long Coccus 1mm Under the microscope But how small it that? To make a bacterium on your hand grow as big as this one, how big would the hand need to grow? Your hand would need to be as long as 150 busses! 150 Time for an experiment Let’s try and see some real bacteria Under the microscope Good bugs & Bad bugs Bad Good Salmonella Good bugs & Bad bugs Bad Good Gonococcus Good bugs & Bad bugs Bad Good Lactobacillus Good bugs & Bad bugs Bad Good Campylobacter Good bugs & Bad bugs Bad Good Staphylococcus Good bugs & Bad bugs Bad Good Penicillium Bacterial Growth Favourable conditions Cells rapidly increase in number Bacterial Growth! Microorganisms and Temperature Bacteria can spread easily Later in the course Superbugs & infection control Experiments on hand washing