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Human Endocrine
System
Endocrine Overview


Hormones- chemical
messengers travel
through body
Target cell or organorgan or cells that a
hormone affects
Control of Hormone Release


Negative feedback mechanism- hormone
release is triggered by stimulus, rising levels
of hormone inhibit further release
Endocrine stimuli


Hormonal- hormones stimulate the release of
others
Humoral- blood stimulates release of hormones
Neural- nerves stimulate hormone release
Anterior Pituitary Gland




Growth Hormone (GH)- affects growth of
skeletal muscles and bones
Prolactin (PRL)- stimulates milk production
after pregnancy
Gonadotropic- regulates hormone activity of
sex organs
Also effects adrenal cortex and thyroid
hormone release
Posterior Pituitary


Oxytocin- helps during
pregnancy
Antidiuretic hormone
(ADH)- inhibits urine
production

Alcohol inhibits ADH
causing increased output
of urine
Thyroid Gland

Thyroid hormone


Controls the rate at
which glucose is
“burned”
Calcitonin

Decreases calcium
levels in blood deposits
on bone
Parathyroid Gland

Parathyroid hormone
(PTH)- regulates
Ca2+ in blood

If Ca2+ level drops
bones is broken down
Adrenal Gland

Adrenal Cortex


Releases hormones that
regulate mineral content in
blood
Adrenal Medulla


Produces epinephrine and
norepinephrine
Helps with stressful situations
Pancreas


Insulin- increases
glucose uptake into cells
and stores in liver
Glucagon- stimulates
breakdown of glucose
stores in the liver
Pineal Gland

Melatonin

Establishes body’s day/ night cycle
Thymus

Thymosin

“Programs” T cells
Gonads


Androgens (male)- sperm formation,
development of male char
Estrogens (female)- development of female
char
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