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Blood Type Codominance Practice Problems
Human blood types are determined by genes that follow the CODOMINANCE pattern of inheritance. There are
two equally dominant alleles (A and B) and one recessive allele (O).
1. Fill in the following chart with the missing information.
Blood Type
(Phenotype)
Possible Genotype(s)
Can donate blood to:
Can receive blood from:
O
ii
A, B, AB, O
(“universal donor”)
O
AB
IAIB
AB
A, B, AB, O
(“universal recipient”)
A
IAIA, IAi
AB , A
O,A
B
IBIB, IBi
AB , B
O,A
2. Write the genotype for each person, based on the given description.
Homozygous for Type B Blood ____ IBIB ______
Heterozygous for Type A Blood ____ IAi ______
Type O Blood ____ii______
Type A Blood and had a parent with Type O Blood ___ IAi ____
Type AB Blood ____ IAIB ______
Blood can be given to any individual ____ii______
Heterozygous for Type B Blood ____ IBi ____
Homozygous for Type A Blood ____ IAIA ______
Can only receive blood from a Type O donor _____ii_____
IB
3. A father is heterozygous for his type B blood (BO) and the mother has
i
type O blood.
a. What are the possible blood types of the babies born from this
couple? Type B and Type O
i
i
IBi
ii
IBi
ii
4. A father has type AB blood and the mother has type O blood.
IA
IB
a. What percentage of their offspring would you expect to have…
i
IAi
IBi
Type A Blood ___50___%
Type B Blood __50____%
i
IAi
IBi
Type AB Blood ___0___%
Type O Blood __0____%
5. A father is heterozygous for his type A blood and a mother is heterozygous for her type B blood.
a. What percentage of their offspring would you expect to have…
IA
Type A Blood ___25___%
i
IB
IAIB
IBi
i
IAi
ii
Type B Blood __25____%
Type AB Blood ___25___%
Type O Blood __25____%
6. Mrs. Weasley has Type A blood but she is not sure if she is homozygous or
heterozygous. Mr. Weasley is completely unsure of his blood type. Their
children have the following blood types: Ron has Type O blood, Fred &
IB
George have type A blood, Ginny has type B blood and Percy has type AB
blood. Show the cross to answer the following questions.
i
IA
i
IAIB
IBi
IAi
ii
a. What is Mrs. Weasley’s genotype? ___IAi ______
b. What is Mr. Weasley’s genotype? ___IBi_____
IA
IA
IB
IAIA
IAIB
i
IAi
IBi
7. In 1968, a couple accused a hospital of switching their baby with
another. DNA fingerprinting did not exist at this time so the hospital traced the
blood types of the family in order to determine if a mistake was made. The
mother had type A blood, the father had type AB blood, and the baby had type
O blood. Use the punnett square to defend your answer to the following
question.
a. Did the hospital make a mistake and switch the baby? _yes!_
8. On a recent episode of CSI, multiple people came forward claiming to be
the parents of the victim. For the first set of parents, the man has type
i
AB blood, the woman has type O blood and yet the victim has type B
blood. Use the punnett square in order to determine if these people
could possibly be the parents of the victim.
i
a. Could these be the parents of the victim? ___yes!____
b. In the chart below, circle the other possible options for
the parents of the victim.
IA
IB
IAi
IBi
IAi
IBi
Couple
Blood Types
Bob and Gina
Type O and Type O
Ted and Susan
Rob and Kelly
Type AB and Type
AB
Type A and Type A
Tricia and James
Type A and Type B