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Online Appendix
Supplement to: Editorial Commentary for JACC:HF
Unraveling the Relationship between Aging and Heart Failure with Preserved
Ejection Fraction: The Importance of Exercise and Normative Reference
Standards
Dalane W. Kitzman,1 Thomas J. O’Neill IV, 1 and Peter H. Brubaker2
Additional References:
1. Kitzman DW, Gardin JM, Gottdiener JS, et al. Importance of heart failure with preserved systolic
function in patients > or = 65 Years of Age. CHS Research Group. Cardiovascular Health Study. Am
J Cardiol 2001; 87:413-9.
2. Senni M, Tribouilloy CM, Rodeheffer RJ, et al. Congestive heart failure in the community: a study
of all incident cases in Olmsted County, Minnesota, in 1991. Circulation 1998; 98:2282-9.
3. Aurigemma GP, Gottdiener JS, Shemanski L, Gardin JM, Kitzman DW. Predictive value of systolic
and diastolic function for incident congestive heart failure in the elderly: The Cardiovacular Health
Study. J Am Coll Cardiol 2001; 37:1042-8.
4. John JM, Haykowsky M, Brubaker P, Stewart K, Kitzman DW. Decreased left ventricular
distensibility in response to postural change in older patients with heart failure and preserved
ejection fraction. American Journal of Physiology - Heart and Circulatory Physiology 2010;
299:H883-H889.
5. Ogawa T, Spina RJ, Martin WH, Kohrt WM, Schechtman KB. Effect of aging, sex, and physical
training on cardiovacular responses to exercise. Circulation 1992; 86:494-503.
6. Kitzman DW, Upadhya B, Taffet GE. Effects of Aging on Cardiovascular Structure and Function. In:
Hazzard's Principles of Geriatric Medicine and Gerontology. McGraw-Hill, 2017.
7. Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA Guideline for the management of heartfailure: a report of the American College of Cardiology Foundation/American Heart Association
Task Force on Practice Guidelines. J Am Coll Cardiol 2013; 62:e147-e239.
8. Edelmann F, Gelbrich G, Dungen H, et al. Exercise Training Improves Exercise Capacity and
Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction: Results of the
Ex-DHF (Exercise training in Diastolic Heart Failure) Pilot Study. J Am Coll Cardiol 2011; 58:1780-91.