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AP2 Lab 2 Cardiac Conduction System, ECG/EKG, Pacemakers, and Cardiac Output J. James Video: Heart beats outside of body Intrinsic Conduction System Fig 18.13 Autorhythmic fibers of the intrinsic conducting system • Not the same as contractile fibers • Are muscle cells but act like neurons • Coordinate the sequence of contraction among the contractile fibers • Components 1. SA Node (sinoatrial) 2. AV Node (atrioventricular ) 3. Bundle of His (AV bundle) 4. L&R bundle branches 5. Purkinje fibers • All have autorhythmicity… • Why? 1. Always ‘leaks’ Na+ and Ca++ inward 2. Become progressively impermeable to K+ leaking outward • The normal sequence … • The advantage … Autorhythmicity / Automaticity Fig 18.12 Pacemakers Single chamber Electrocardiogram = ECG = EKG Fig 18.16 Video: Sinus rhythms 4 min Normal Sinus Rhythm Sinus Bradycardia Sinus Tachycardia ECG Tracings: one ‘normal,’ three dysrhythmias / arrhythmias Fig 18.18 Normal sinus rhythm, NSR Junctional rhythm 2nd degree heart block Ventricular fibrillation Asystole Implantable Cardioverter Defibrillators, ICDs Cardiac Output CO def… Formula: CO = HR x SV HR… SV… Avg. 70 ml/beat Formula: SV = EDV-ESV SV/EDV = “ejection fraction” - usually 60-90% of EDV CO can increase 7X (700%) - Q&A Q&A Q&A Q&A