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Endocrine Systems Hypothalamus-Secretes Several neurohormones, such as Dopamine, that stimulate or inhibit anterior pituitary function Pineal gland-Makes melatonin, which regulates daily rhythms and seasonal reproduction in some mammals Parathyroid glands-Make parathyroid hormone, which increases blood calcium Thyroid-Makes thyroxine and triiodothyronine, which regulate metabolic rate, growth, and differentiation Adrenal glands: Medulla-Makes epinephrine and norepinephrine, which mediate the “fight-orflight” response Cortex-Makes aldosterone, which regulates Na and K balance in the blood and makes glucocotricoids Kidneys-Secrete erythropoietin, which regulates production of red blood cells; also convert vitamin D to an active hormone Pituitary gland: Anterior Pituitary glandProduces 6 hormones with diverse actions (ACTH, GH, TSH, PRL, LH, FSH) Posterior Pituitary glandSecretes oxytocin and antidiuretic hormone Pancreas-Makes insulin, which lowers blood glucose, and glucagon, which raises blood glucose Testes-Produce androgens, such as testosterone, which control reproduction in males Acknowledgements: www.mic.ki.se, www.cdc.gov, www.brookerbiology.com Ovaries-Produce estorgens such as estradiol, and progesterone, which control reproduction in females Disorders: Hyperthyroidism: Results from excessive production of the thyroid hormones T-4 and T-3 Diabetes Mellitus: The body’s immune system destroys pancreatic beta cells, which make the hormone insulin Diabetes Insipidus: Caused by lack of the antidiuretic hormone vassopressin, which controls water balance by concentrating urine. Adrenoleukodystrophy: The enzyme that breaks down the very long chain fatty acids is not produced and these fatty acids accumulate in the brain and adrenal cortex Danielle Marsh 2009