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Curriculum Vitae John Blair Hamner, M.D., FACS Work Address Assistant Professor-Surgical Oncology Department Of Surgery Tulane University School of Medicine 1430 Tulane Ave., SL-22 New Orleans, LA 70112 Phone: (504)988-2307 Medical Licensure Louisiana (number upon request) California (number upon request) Certification American Board of Surgery-General Surgery Medical Education July 2013-June 2015 City of Hope National Medical Center, Duarte, CA Clinical Fellow, Surgical Oncology July 2005-June 2007 St. Jude Children’s Research Hospital, Memphis, TN Resident Research Fellow, Department of Surgery Research Focus: Pediatric solid tumors Tumor angiogenesis/anti-angiogenic cancer therapy Tumor vascular normalization June 2003- July 2010 1 University of Tennessee Health Science Center, Memphis, TN Resident Physician in the Department of Surgery August 1999- June May 2003 Louisiana State University Health Science Center School of Medicine, Shreveport, LA Doctor of Medicine Undergraduate Education August 1993- May 1998 Nicholls State University, Thibodaux, LA Bachelor of Science (Biological Sciences) May 1997 Work Experience July 2013-Present City of Hope National Medical Center, Duarte, CA Clinical Fellow, Surgical Oncology August 2010-June 2013 Ochsner Health System: North Shore Region Covington, LA Attending General Surgeon June 2003- July 2010 University of Tennessee Health Science Center, Memphis, TN Resident Physician in the Department of Surgery Professional Memberships American College of Surgeons AHPBA ASCO Society of Surgical Oncology Harwell Wilson Surgical Society Awards and Honors City of Hope GME Research Travel Award, March 2015. Amount $1000. 2 Other Certificates Advanced Cardiac Life Support Fundamentals of Laparoscopic Surgery Clinical Investigator Training Program (City of Hope) Publications 1. Hamner JB, White M, Crowder C, Singh G. Resection of metachronous pancreatic cancer 4 years after pancreaticoduodenectomy for stage III pancreatic adenocarcinoma. World J Surg Oncol. 2015 Sept 30;13:290 2. Choi AH, Hamner JB, Merchant S, Trisal V, Chow W, Garberoglio CA, Kim J. Underreporting of Gatrointestinal Stromal Tumors: Is the True Incidence Being Captured? J Gastrointest Surg. 2015 Sept;19(9):1699-703 3. Luyimbazi D, Nelson RA, Choi AH, Li L, Chao J, Sun V, Hamner JB, Kim J. Estimates of conditional survival in gastric cancer reveal a reduction of racial disparities with longterm follow-up. J Gastrointest Surg. 2015 Feb;19(2):251-7. 4. McGee MC, Hamner JB, Williams RF, Rosatti SF, Sims TL, Ng CY, Gaber MW, Calabrese C, Wu J, Nathwani AC, Duntsch C, Merchant TE, Davidoff AM. Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1537-45 5. Sims TL, McGee M, Williams AL, Tracey L, Hamner JB, Ng C, Wu J, Gaber MW, McCarville B, Nathwani AC, Davidoff AM. IFN-beta restricts tumor growth and sensitizes alveolar rhabdomyosarcoma to ionizing radiation. Mol Cancer Ther. 2010 Mar;9(3):76171. 6. Sims TL Jr, Hamner JB, Bush RA, Fischer PE, Kim SU, Aboody KS, McCarville B, Danks, MK, Davidoff AM. Neural Progenitor cell-mediated delivery of osteoprotegerin limits disease progression in a preclinical model of neuroblastoma bone metastasis. Journal of Pediatric Surgery. 2009 Jan;44(1):204-210. 7. Sims TL Jr, Hamner JB, Bush RA, Williams RF, Zhou J, Kim SU, Aboody KS, Danks MK, Davidoff AM. Neural progenitor cell-mediated delivery of interferon-beta improves neuroblastoma response to cyclophosphamide. Annals of Surgical Oncology, 2008 November;15(11):3258-3267. 3 8. Hamner JB, Sims TL, Cutshaw A, Dickson PV, Rosati S, McGee M, Ng CY, Davidoff AM. The efficacy of combination therapy using adeno-associated virus interferon-beta and Trichostatin A in vitro and in a murine model of neuroblastoma. Journal of Pediatric Surgery, 2008 January;43(1):177-182. 9. Hamner JB, Dickson PV, Sims TL, Zhou J, Spence Y, Ng CY, Davidoff AM. Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma. Surgery. 2007 August;142(2):793-799. 10. Dickson PV, Hamner B, Ng CY, Hall MM, Zhou J, Hargrove PW, McCarville MB, Davidoff AM. In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma. Journal of Pediatric Surgery. 2007 July;42(7):1172-1179. 11. Dickson PV, Hamner JB, Sims TL, Fraga CH, Ng CY, Rajasekeran S, Hagedorn NL, McCarville MD, Stewart CF, Davidoff AM. Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy. Clinical Cancer Research. 2007 July 1;13(13):3942-3950. 12. Dickson PV, Hamner, JB, Streck CJ, Ng CY, McCarville MB, Calabrese C, Gilbertson RJ, Stewart CF, Wilson CM, Gaber MW, Pfeffer LM, Skapwk SX, Nathwani AC, Davidoff AM. Continuous delivery of IFN-β promotes sustained maturation of intratumoral vasculature. Molecular Cancer Research. 2007 June;5(6):531-42. 13. Hamner JB and Fleming MD. Lymphedema therapy reduces the volume of edema and pain in breast patients with breast cancer. Annals of Surgical Oncology. 2007 June:14(6);1904-08. 14. Calbrese C, Poppleton H, Kocak M, Fuller C, Hamner B, Oh EY, Gaber MW, Finklestein D, Allen M, Frank A, Bayazitov IE, Zakharenko SS, Gajjar A, Davidoff A, Gilbertson RJ. A perivascular niche for brain tumor stem cells. Cancer Cell. 2007 Jan;11(1):69-82. 15. Dickson PV, Hagedorn NL, Hamner JB, Fraga CH, Ng CY, Stewart CF, Davidoff AM. Interferon-β mediated vessel stabilization improves delivery and efficacy of systemically administered topotecan in a murine neuroblastoma model. Journal of Pediatric Surgery. 2007 Jan;42(1):160-165. 16. Dickson PV, Hamner JB, Burger RA, Garcia E, Ouma AA, Kim SU, Ng CY, Gray JT, Aboody KS, Danks MK, Davidoff AM. Intravascular administration of tumor tropic neural progenitor cells permits targeted delivery of interferon-β and restricts tumor growth in a murine model of disseminated neuroblastoma. Journal of Pediatric Surgery. 2007 Jan;42(1): 48-53. 4 17. Dickson PV, Hamner JB, Cauthen LA, Ng CY, McCarville MB, Davidoff AM. Efficacy of Zoledronate against neuroblastoma. Surgery. 2006 Aug:140(2): 227-35. Book Chapters 1. Hamner, J, Kim J: Laparoscopic Distal Gastrectomy: in Surgery for Cancers of the Gastrointestinal Tract: A Step-by-Step Approach. Kim and Garcia-Agguillar (eds). 2014. 2. Hamner J, Davidoff A, Shochat S. Neuroblastoma: in Reoperative Pediatric Surgery. Teich and Caniano (Eds). 2008. Presentations at National/International Meetings 1. Surgery for Recurrent Pancreatic Cancer. March 2015, Society of Surgical Oncology Cancer Symposium. Presented in the fellows educational session. Houston, TX. 2. Outpatient Thyroidectomy: Current Practice and Utilization Trends in California. February 2015, Academic Surgical Congress. Las Vegas, NV. 3. The Evolving Role of Liver Resection for Metastatic Urologic Tumors. March 2014, IHPBA World Congress. Seoul, South Korea 4. Pre-operative Staging of Gastric Adenocarcinoma with CT Gastrography and 3-D Reconstruction: Report of a Pilot Study. March 2014, Society of Surgical Oncology Cancer Symposium. Phoenix, AZ (Poster Presentation). 5. The Combination of Interferon-Beta and Trichostatin A Inhibits Tumor Growth In Vivo and in a Murine Model of Neuroblastoma. May 2007, American Pediatric Surgical Association 38th Annual Meeting. Orlando, FL 6. Bortezomib Inhibits Angiogenesis and Reduces Tumor Burden in a Murine Model of Neuroblastoma. February 2007, 2nd Annual Academic Surgical Congress (abstract accepted by the Society of University Surgeons). Phoenix, AZ. 7. Continuous Delivery of Interferon-beta Sensitizes Human Gliomas to Ionizing Radiation. October 2006, Clinical Congress of the American College of Surgeons: Surgical Forum. Chicago, IL 5 8. Interferon-beta Mediated Vessel Stabilization Improves Delivery and Efficacy of Systemically Administered Topotecan in a Murine Model of Neuroblastoma. March 2006, American Pediatric Surgical Association. Hilton Head, SC. 9. Lymphedema Therapy Reduces the Volume of Edema and Pain in Breast Cancer Patients. February 2006, Society of Surgical Oncology Cancer Symposium. San Diego, CA Abstracts Presented as Posters 1. Hamner JB, White M, Ituarte P, Singh G. Outcomes of Liver Directed Therapy for Metastatic Carcinoid Tumors. March 2015, Society of Surgical Oncology Cancer Symposium. Houston, TX. 2. Hamner JB, Choi AH, Merchant S, Trisal V, Chow W, Garberoglio CA, Kim J. Underreporting of Gatrointestinal Stromal Tumors: Is the True Incidence Being Captured? March 2015, Society of Surgical Oncology Cancer Symposium. Houston, TX. 3. Lewis A, Ituarte PH, Hamner JB, Singh G, Kessler J. Major Liver Resection Followed by Radioembolization: Is it Safe? March 2015, Society of Surgical Oncology Cancer Symposium. Houston, TX. 4. Hamner JB, Nelson RA, Lee B, Singh G, Park J, Kim J. Pre-operative Staging of Gastric Adenocarcinoma with CT Gastrography and 3-D Reconstruction: Report of a Pilot Study. March 2014, Society of Surgical Oncology Cancer Symposium. Phoenix, AZ. Other Presentations 1. Multidisciplinary Treatment of Rectal Cancer. Department of Radiation Oncology Education Conference. City of Hope National Medical Center, Duarte, CA. June 2015. 2. Workup of Thyroid Nodules and the Management of Well Differentiated Thyroid Cancer. Division of Surgical General Surgical Oncology Education Conference. City of Hope National Medical Center, Duarte, CA December 2014. 3. Transanal Excision in Rectal Cancer. Division of General Surgical Oncology Education Conference. City of Hope National Medical Center, Duarte, CA April 2014. 6 4. Cystic Neoplasms of the Pancreas. Department of Surgery Grand Rounds. University of Tennessee Health Science Center, Memphis, TN May 2010. 5. Bortezomib Restricts Tumor Progression and Angiogenesis in a Murine Model of Neuroblastoma. Tennessee Chapter of the American College of Surgeons, Paris Landing, TN, August 2007. 6. The Anti-tumor Efficacy of continuous Delivery of Interferon-Beta in a Murine Model of Glioblastoma. Harwell-Wilson Surgical Society, Memphis, TN June 2007. 7. Continuous Delivery of Interferon-beta Sensitizes Human Gliomas to Ionizing Radiation. Tennessee Chapter of the American College of Surgeons, Fall Creek Falls, TN, August 2006. 8. The Anti-tumor and Anti-angiogenic Effects of Bortezomib in a Murine Model of Glioblastoma. Harwell-Wilson Surgical Society, Memphis, TN, June 2006. 9. Does Gene Therapy With Interferon-Beta Sensitize Human Gliomas to Ionizing Radiation? Memphis Surgical Society, February 2006 Clinical Interests Melanoma Sarcoma Gastric Cancer HPB Oncology Multidisciplinary Cancer Care Interests and Hobbies Saltwater fishing College and NFL football Cooking 7