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EEG (Electroencephalogram) EEG (Electroencephalogram) The brain generates rhythmical potential which originate in the individual neurons of the brain. These potential get summated as millions of cell discharge synchronously & appear as a surface waveform, known as the “Electroencephalogram”. a nerve impulse which is seen as a change in membrane potential, resulting from depolarization of the cell, shortly afterwards, repolarization occurs. EEG Generation of large EEG signals by synchronous activity Typical EEG signal waveform Bands F Range Delta (δ) 0.5-4 Hz Theta (θ) 4-8 Hz Alpha (𝛼) 8-13 Hz Beta (β) 13-22Hz Gamma (γ) >30Hz EEG signal can be picked up with electrodes from the scalp. Amplitude of wave from scalp is around 50μV PP to hundreds of μ V PP from brain. Its normal Frequency range from 0.5 to 50Hz. Frequency information is significant thus its range classified into 5 bands Delta Wave Theta Wave Alpha Wave Beta Wave Gamm a wave EEG signal waveform Results: • Signal range : 2µV (brain death ) – several hundred µV. • The frequency bands in EEG: 1- Delta (<4 Hz): sleep of infants & deep sleep stages of normal adults. 2- Theta (4-8 Hz):normal children as well as during drowsiness and sleep in adults. 3- Alpha (8-14 Hz): mostly around 50 µV, normal adults during relaxed and mentally inactive awaken state. 4- Beta (14-30 Hz): mostly below 30 µV , by stress and tension. 5- Gamma (>30 Hz): Usually, it is not of clinical and physiological interests and therefore often filtered out in EEG recordings Different types of brain waves in normal EEG Rhythm Frequency Amplitude (Hz) (uV) Recording & Location Beta(β) 14 - 30 20 mental activity, emotional distress, tension Frontal region Alpha(α) 8 – 13 50 – 100 Adults, rest, eyes closed. Occipital region Theta(θ) 5–7 50 Children, drowsy adult, Occipital Delta(δ) 2–4 50 infants in sleep Use of EEG In Medical Science: • Epilepsy »Generalized seizures. (a sudden attack of illness, especially a stroke or an epileptic fit.) • Localize brain tumors. • Sleep disorders »Narcolepsy »Sleep apnea syndrome »Insomnia and parasomnia • Helpful in knowing the cortical activity, toxicity, hypoxia and encephalopathy Use of EEG In Medical Science: • Detects cortical dysfunction. • Helpful in paralytic patients. • Determination of brain death. – Flat EEG(absence of electrical activity) with voltage around 2uV. ELECTROMYOGRAM (EMG) ELECTROMYOGRAM (EMG) • Electromyogram (EMG) is a technique for evaluating and recording the activation signal of muscles. • Electromyograph detects the electrical potential generated by muscle cells when these cells contract and relax. Fluid Distribution • Concentration of ions different inside vs. outside of cell membrane • This results in an electrical potential difference known as a MEMBRANE POTENTIAL • Typical magnitude of membrane potential is -60 and -90 mV (interior of cell is negatively charged) (resting) • This potential can change within fractions of seconds to +20 to +50 mV • This rapid change is called an ACTION POTENTIAL Skeletal Muscle Organization • Series Elastic Components – Tendons & Bones – Fascia, Endomysium, Perimysium and the Epimysium • Excitable Vs NonExcitable – Muscle tissue IS The Muscle Fiber at the electrophysiological level • • • Resting Potential – the voltage across an unstimulated cell Muscle Cell = -90mV Established by Depolarization- entering +ve ion inside cell Repolarization -: +ve ion moves outside of cell Action Potential of a Neuron EMG Waves Raw EMG Full-wave Rectified EMG EMG Waves • Typical EMG signal has 0.1 to 0.5 mV peak • They may contain frequency component up to 10 KHz. Use of EMG: • Detection of Sensory Loss • In patient of paralysis.