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Genotypes
HH
Hh
hh
XHXH
XHXh
XhXh
XHY
XhY
Homozygous Dominant
Heterozygous Dominant
Homozygous Recessive
Homozygous Dominant Female
Heterozygous Dominant Female
Homozygous Recessive Female
Dominant Male
Recessive Male
A woman has the recessive disorder cystic
fibrosis and marries a man without the disease.
Determine the genotypic and phenotypic ratio
of the children they plan to have.
What are the chances of a child having cystic
fibrosis from the couple?
A woman and a man are both heterozygous for
the dominant disorder Huntington’s disease.
What are the chances of their children NOT
having the disorder?
Determining inheritance patterns of Pedigrees
• Dominant inheritance– Trait appears in every generation
– Many individuals have the trait
• Recessive inheritance– Trait skips generations
– Few individuals have the trait
• Sex-linked inheritance– More males have the trait than females
– Can be dominant or recessive
What is the inheritance pattern of the following
pedigree?
What are the genotypes of individuals I-1 and I-2?
What were the chances of I-1 and I-2’s children
having the trait?
What is the inheritance pattern of the following
pedigree?
What are the genotypes of I1 and I2?
What are the chances of III3 and III4’s next child
having the trait?
• A woman is heterozygous for Type A blood
and her husband has Type AB blood. What
are the chances of their child having Type A
blood? Type AB blood? Type O blood? Type
B blood?
• A man has the sex-linked, recessive trait redgreen colorblindness and his wife is a carrier
for red-green colorblindness. What are the
chances of their child having red-green
colorblindness? What are the chances of their
next girl having red-green colorblindness?